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PDB: 155 results

7M3F
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BU of 7m3f by Molmil
Asymmetric Activation of the Calcium Sensing Receptor Homodimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G.
Deposit date:2021-03-18
Release date:2021-06-30
Last modified:2021-07-21
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Asymmetric activation of the calcium-sensing receptor homodimer.
Nature, 595, 2021
8V6U
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BU of 8v6u by Molmil
5HT2AR-miniGq heterotrimer in complex with a novel agonist obtained from large scale docking
Descriptor: 4-{(3R)-1-[(1R)-1-(pyrimidin-2-yl)ethyl]piperidin-3-yl}phenol, 5-hydroxytryptamine receptor 2A, G protein alpha-subunit q (Gi2-mini-Gq chimera), ...
Authors:Gumpper, R.H, Wang, L, Kapolka, N, Skiniotis, G, Roth, B.L.
Deposit date:2023-12-03
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:AlphaFold2 structures guide prospective ligand discovery.
Science, 2024
8EL7
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BU of 8el7 by Molmil
CryoEM structure of Resistance to Inhibitors of Cholinesterase-8B (Ric-8B) in complex with G alpha s
Descriptor: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Isoform 1 of Synembryn-B
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2022-09-23
Release date:2023-03-01
Last modified:2023-05-17
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structures of Ric-8B in complex with G alpha protein folding clients reveal isoform specificity mechanisms.
Structure, 31, 2023
8EL8
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BU of 8el8 by Molmil
CryoEM structure of Resistance to Inhibitors of Cholinesterase-8B (Ric-8B) in complex with olfactory G protein alpha olf
Descriptor: Guanine nucleotide-binding protein G(olf) subunit alpha, Isoform 1 of Synembryn-B
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2022-09-23
Release date:2023-03-01
Last modified:2023-05-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of Ric-8B in complex with G alpha protein folding clients reveal isoform specificity mechanisms.
Structure, 31, 2023
8GHV
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BU of 8ghv by Molmil
Cannabinoid Receptor 1-G Protein Complex
Descriptor: (5Z,8Z,11Z,13S,14Z)-N-[(2R)-1-hydroxypropan-2-yl]-13-methylicosa-5,8,11,14-tetraenamide, Cannabinoid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Krishna Kumar, K, Robertson, M.J, Skiniotis, G, Kobilka, B.K.
Deposit date:2023-03-12
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis for activation of CB1 by an endocannabinoid analog.
Nat Commun, 14, 2023

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數據於2024-06-05公開中

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