3LY8
| |
3LRH
| |
3LYA
| |
3LRG
| Structure of anti-huntingtin VL domain | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, IMIDAZOLE, anti-huntingtin VL domain | 著者 | Schiefner, A, Chatwell, L, Skerra, A. | 登録日 | 2010-02-11 | 公開日 | 2011-02-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | A Disulfide-Free Single-Domain V(L) Intrabody with Blocking Activity towards Huntingtin Reveals a Novel Mode of Epitope Recognition. J.Mol.Biol., 414, 2011
|
|
3LY9
| |
3LY7
| |
5N5U
| |
3MBT
| |
1N0S
| ENGINEERED LIPOCALIN FLUA IN COMPLEX WITH FLUORESCEIN | 分子名称: | 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, Bilin-binding protein, SULFATE ION | 著者 | Korndoerfer, I.P, Skerra, A. | 登録日 | 2002-10-15 | 公開日 | 2003-08-05 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystallographic analysis of an "anticalin" with tailored specificity for fluorescein reveals high structural plasticity of the lipocalin loop region. Proteins, 53, 2003
|
|
3KQ0
| Crystal structure of human alpha1-acid glycoprotein | 分子名称: | (2R)-2,3-dihydroxypropyl acetate, Alpha-1-acid glycoprotein 1, CHLORIDE ION | 著者 | Schiefner, A, Schonfeld, D.L, Ravelli, R.B.G, Mueller, U, Skerra, A. | 登録日 | 2009-11-17 | 公開日 | 2010-02-02 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The 1.8-A crystal structure of alpha1-acid glycoprotein (Orosomucoid) solved by UV RIP reveals the broad drug-binding activity of this human plasma lipocalin. J.Mol.Biol., 384, 2008
|
|
4I5D
| Crystal structure of Ralstonia sp. alcohol dehydrogenase in its apo form | 分子名称: | Alclohol dehydrogenase/short-chain dehydrogenase, SULFATE ION | 著者 | Jarasch, A, Lerchner, A, Meining, W, Schiefner, A, Skerra, A. | 登録日 | 2012-11-28 | 公開日 | 2013-06-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. Alcohol dehydrogenase toward NADH cosubstrate specificity. Biotechnol.Bioeng., 110, 2013
|
|
4I5E
| Crystal structure of Ralstonia sp. alcohol dehydrogenase in complex with NADP+ | 分子名称: | Alclohol dehydrogenase/short-chain dehydrogenase, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Jarasch, A, Lerchner, A, Meining, W, Schiefner, A, Skerra, A. | 登録日 | 2012-11-28 | 公開日 | 2013-06-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. Alcohol dehydrogenase toward NADH cosubstrate specificity. Biotechnol.Bioeng., 110, 2013
|
|
4I5G
| Crystal structure of Ralstonia sp. alcohol dehydrogenase mutant N15G, G37D, R38V, R39S, A86N, S88A | 分子名称: | Alclohol dehydrogenase/short-chain dehydrogenase | 著者 | Jarasch, A, Lerchner, A, Meining, W, Schiefner, A, Skerra, A. | 登録日 | 2012-11-28 | 公開日 | 2013-06-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. Alcohol dehydrogenase toward NADH cosubstrate specificity. Biotechnol.Bioeng., 110, 2013
|
|
4I5F
| Crystal structure of Ralstonia sp. alcohol dehydrogenase mutant N15G, G37D, R38V, R39S | 分子名称: | Alclohol dehydrogenase/short-chain dehydrogenase | 著者 | Jarasch, A, Lerchner, A, Meining, W, Schiefner, A, Skerra, A. | 登録日 | 2012-11-28 | 公開日 | 2013-06-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. Alcohol dehydrogenase toward NADH cosubstrate specificity. Biotechnol.Bioeng., 110, 2013
|
|
1T0V
| NMR Solution Structure of the Engineered Lipocalin FluA(R95K) Northeast Structural Genomics Target OR17 | 分子名称: | BILIN-BINDING PROTEIN | 著者 | Mills, J.L, Liu, G, Skerra, A, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2004-04-13 | 公開日 | 2005-06-14 | 最終更新日 | 2024-10-30 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure and dynamics of the engineered fluorescein-binding lipocalin FluA reveal rigidification of beta-barrel and variable loops upon enthalpy-driven ligand binding. Biochemistry, 48, 2009
|
|
4IAW
| Engineered human lipocalin 2 (C26) in complex with Y-DTPA | 分子名称: | N-{(1S,2S)-2-[bis(carboxymethyl)amino]cyclohexyl}-N-{(2R)-2-[bis(carboxymethyl)amino]-3-[4-({[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamothioyl}amino)phenyl]propyl}glycine, Neutrophil gelatinase-associated lipocalin, YTTRIUM (III) ION | 著者 | Eichinger, A, Skerra, A. | 登録日 | 2012-12-07 | 公開日 | 2013-06-19 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-guided engineering of Anticalins with improved binding behavior and biochemical characteristics for application in radio-immuno imaging and/or therapy J.Struct.Biol., 185, 2014
|
|
4IDF
| Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADPH and HMF | 分子名称: | 1,2-ETHANEDIOL, 4-hydroxy-5-methylfuran-3(2H)-one, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Schiefner, A, Skerra, A. | 登録日 | 2012-12-12 | 公開日 | 2013-04-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone J.Biol.Chem., 288, 2013
|
|
4IDC
| Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADPH and HDMF | 分子名称: | (2R)-4-hydroxy-2,5-dimethylfuran-3(2H)-one, 1,2-ETHANEDIOL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Schiefner, A, Skerra, A. | 登録日 | 2012-12-12 | 公開日 | 2013-04-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone J.Biol.Chem., 288, 2013
|
|
4IDB
| Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADP+ | 分子名称: | 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Ripening-induced protein, ... | 著者 | Schiefner, A, Skerra, A. | 登録日 | 2012-12-12 | 公開日 | 2013-04-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone J.Biol.Chem., 288, 2013
|
|
4IDD
| Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADPH and EHMF | 分子名称: | (2R)-2-ethyl-4-hydroxy-5-methylfuran-3(2H)-one, 1,2-ETHANEDIOL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Schiefner, A, Skerra, A. | 登録日 | 2012-12-12 | 公開日 | 2013-04-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone J.Biol.Chem., 288, 2013
|
|
4IDE
| Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADP+ and EDHMF | 分子名称: | (2E)-2-ethylidene-4-hydroxy-5-methylfuran-3(2H)-one, 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Schiefner, A, Skerra, A. | 登録日 | 2012-12-12 | 公開日 | 2013-04-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone J.Biol.Chem., 288, 2013
|
|
4IDA
| |
4IAX
| Engineered human lipocalin 2 (CL31) in complex with Y-DTPA | 分子名称: | N-{(1S,2S)-2-[bis(carboxymethyl)amino]cyclohexyl}-N-{(2R)-2-[bis(carboxymethyl)amino]-3-[4-({[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamothioyl}amino)phenyl]propyl}glycine, Neutrophil gelatinase-associated lipocalin, YTTRIUM (III) ION | 著者 | Eichinger, A, Skerra, A. | 登録日 | 2012-12-07 | 公開日 | 2013-06-19 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-guided engineering of Anticalins with improved binding behavior and biochemical characteristics for application in radio-immuno imaging and/or therapy J.Struct.Biol., 185, 2014
|
|