2ZQU
 
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2ZR4
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2ZR5
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6K3O
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6K43
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2ZQS
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6K4M
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2ZR6
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3ELP
 | | Structure of cystationine gamma lyase | | Descriptor: | Cystathionine gamma-lyase | | Authors: | Sun, Q, Sivaraman, J. | | Deposit date: | 2008-09-23 | | Release date: | 2008-11-18 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S
J.Biol.Chem., 284, 2009
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2ZQT
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3EBW
 | | Crystal structure of major allergens, Per a 4 from cockroaches | | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Per a 4 allergen | | Authors: | Tan, Y.W, Chan, S.L, Chew, F.T, Sivaraman, J, Mok, Y.K. | | Deposit date: | 2008-08-28 | | Release date: | 2008-12-02 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structures of two major allergens, Bla g 4 and Per a 4, from cockroaches and their IgE binding epitopes.
J.Biol.Chem., 284, 2008
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2MQ1
 | | Phosphotyrosine binding domain | | Descriptor: | E3 ubiquitin-protein ligase Hakai, ZINC ION | | Authors: | Mukherjee, M, Jing-Song, F, Sivaraman, J. | | Deposit date: | 2014-06-11 | | Release date: | 2014-08-06 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Dimeric switch of Hakai-truncated monomers during substrate recognition: insights from solution studies and NMR structure.
J.Biol.Chem., 289, 2014
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2OVS
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1K75
 | | The L-histidinol dehydrogenase (hisD) structure implicates domain swapping and gene duplication. | | Descriptor: | GLYCEROL, L-histidinol dehydrogenase, SULFATE ION | | Authors: | Barbosa, J.A.R.G, Sivaraman, J, Li, Y, Larocque, R, Matte, A, Schrag, J, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | Deposit date: | 2001-10-18 | | Release date: | 2002-02-27 | | Last modified: | 2014-11-12 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1MHW
 | | Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides | | Descriptor: | 4-biphenylacetyl-Cys-(D)Arg-Tyr-N-(2-phenylethyl) amide, Cathepsin L | | Authors: | Chowdhury, S, Sivaraman, J, Wang, J, Devanathan, G, Lachance, P, Qi, H, Menard, R, Lefebvre, J, Konishi, Y, Cygler, M, Sulea, T, Purisima, E.O. | | Deposit date: | 2002-08-21 | | Release date: | 2002-12-11 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides
J.Med.Chem., 45, 2002
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4O7D
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1CJL
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4N7D
 | | Selenomethionine incorporated Bla g 4 | | Descriptor: | Bla g 4 allergen variant 1, CITRIC ACID, GLYCEROL | | Authors: | Offermann, L.R, Chan, S.L, Osinski, T, Tan, Y.W, Chew, F.T, Sivaraman, J, Mok, Y.K, Minor, W, Chruszcz, M. | | Deposit date: | 2013-10-15 | | Release date: | 2014-05-21 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The major cockroach allergen Bla g 4 binds tyramine and octopamine.
Mol.Immunol., 60, 2014
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1PVJ
 | | Crystal structure of the Streptococcal pyrogenic exotoxin B (SpeB)- inhibitor complex | | Descriptor: | (3R)-3-{[(BENZYLOXY)CARBONYL]AMINO}-2-OXO-4-PHENYLBUTANE-1-DIAZONIUM, pyrogenic exotoxin B | | Authors: | Ziomek, E, Sivaraman, J, Doran, J, Menard, R, Cygler, M. | | Deposit date: | 2003-06-27 | | Release date: | 2004-09-28 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Inhibition of autoprocessing of the streptococcal pyrogenic exotoxin B (speB). Crystal structure of the proenzyme-inhibitor complex
To be published
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5XWE
 | | Structure of a three finger toxin from Ophiophagus hannah venom | | Descriptor: | CHLORIDE ION, GLYCEROL, Weak toxin DE-1 homolog 1, ... | | Authors: | Jobichen, C, Roy, A, Kini, R.M, Sivaraman, J. | | Deposit date: | 2017-06-29 | | Release date: | 2018-07-11 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of a three finger toxin from Ophiophagus hannah venom
To Be Published
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5YDX
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5YDY
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7EDD
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7E0W
 | | Crystal Structure of BCH domain from S. pombe | | Descriptor: | Putative Rho GTPase-activating protein C1565.02c, TETRAETHYLENE GLYCOL | | Authors: | Chichili, V.P.R, Jobichen, C, Sivaraman, J. | | Deposit date: | 2021-01-28 | | Release date: | 2021-03-31 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | A novel intertwined anti-parallel dimeric structure of scaffold BCH domain regulates RhoA and RhoGAP functions
Proc.Natl.Acad.Sci.USA, 2021
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7FCF
 | | Crystal structure of T6SS Hcp protein | | Descriptor: | Fimbrial protein | | Authors: | Jobichen, C, Sivaraman, J. | | Deposit date: | 2021-07-14 | | Release date: | 2022-07-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Bacterial antagonism of Chromobacterium haemolyticum and characterization of its putative type VI secretion system.
Res.Microbiol., 173, 2022
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