3ELP
Structure of cystationine gamma lyase
Summary for 3ELP
Entry DOI | 10.2210/pdb3elp/pdb |
Descriptor | Cystathionine gamma-lyase (2 entities in total) |
Functional Keywords | alpha beta protein, alternative splicing, amino-acid biosynthesis, cysteine biosynthesis, cytoplasm, disease mutation, lyase, phosphoprotein, polymorphism, pyridoxal phosphate |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: P32929 |
Total number of polymer chains | 4 |
Total formula weight | 180013.26 |
Authors | Sun, Q.,Sivaraman, J. (deposition date: 2008-09-23, release date: 2008-11-18, Last modification date: 2023-11-01) |
Primary citation | Sun, Q.,Collins, R.,Huang, S.,Holmberg-Schiavone, L.,Anand, G.S.,Tan, C.H.,van-den-Berg, S.,Deng, L.-W.,Moore, P.K.,Karlberg, T.,Sivaraman, J. Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S J.Biol.Chem., 284:3076-3085, 2009 Cited by PubMed: 19019829DOI: 10.1074/jbc.M805459200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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