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PDB: 13 件

5UIV
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Structure of Thymidylate Kinase from Candida albicans Reveals Origin of Broad Substrate Specificity and a Novel Structural Element.
分子名称: ADENOSINE-5'-DIPHOSPHATE, Bifunctional thymidylate/uridylate kinase, MAGNESIUM ION, ...
著者Sinha, K, Rule, G.S.
登録日2017-01-15
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The Structure of Thymidylate Kinase from Candida albicans Reveals a Unique Structural Element.
Biochemistry, 56, 2017
8G88
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Human Oct4 bound to nucleosome with human nMatn1 sequence
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G8B
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Nucleosome with human nMatn1 sequence in complex with Human Oct4
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G8G
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Interaction of H3 tail in LIN28B nucleosome with Oct4
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G87
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Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of Oct4 bound region)
分子名称: POU domain, class 5, transcription factor 1, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G86
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BU of 8g86 by Molmil
Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of nucleosome)
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G8E
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Human Oct4 bound to nucleosome with human LIN28B sequence
分子名称: LIN28B DNA (32-MER), POU domain, class 5, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
1FV3
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THE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH AN ANALOGUE OF ITS GANGLIOSIDE RECEPTOR GT1B
分子名称: ETHYL-TRIMETHYL-SILANE, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-beta-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, PHOSPHATE ION, ...
著者Fotinou, C, Emsley, P, Black, I, Ando, H, Ishida, H, Kiso, M, Sinha, K.A, Fairweather, N.F, Isaacs, N.W.
登録日2000-09-18
公開日2001-09-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin.
J.Biol.Chem., 276, 2001
1FV2
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The Hc fragment of tetanus toxin complexed with an analogue of its ganglioside receptor GT1B
分子名称: ETHYL-TRIMETHYL-SILANE, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-beta-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, PHOSPHATE ION, ...
著者Fotinou, C, Emsley, P, Black, I, Ando, H, Ishida, H, Kiso, M, Sinha, K.A, Fairweather, N.F, Isaacs, N.W.
登録日2000-09-18
公開日2001-09-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin.
J.Biol.Chem., 276, 2001
5HLK
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BU of 5hlk by Molmil
Crystal structure of the ternary EcoRV-DNA-Lu complex with cleaved DNA substrate.
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*AP*GP*AP*TP)-3'), DNA (5'-D(*AP*TP*CP*TP*TP*TP)-3'), ...
著者Sangani, S.S, Kehr, A.D, Sinha, K, Rule, G.S, Jen-Jacobson, L.
登録日2016-01-15
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Metal Ion Binding at the Catalytic Site Induces Widely Distributed Changes in a Sequence Specific Protein-DNA Complex.
Biochemistry, 55, 2016
5F8A
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Crystal structure of the ternary EcoRV-DNA-Lu complex with uncleaved DNA substrate. Lanthanide binding to EcoRV-DNA complex inhibits cleavage.
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*T)-3'), LUTETIUM (III) ION, ...
著者Sangani, S.S, Kehr, A.D, Sinha, K, Rule, G.S, Jen-Jacobson, L.
登録日2015-12-09
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Metal Ion Binding at the Catalytic Site Induces Widely Distributed Changes in a Sequence Specific Protein-DNA Complex.
Biochemistry, 55, 2016
6AIE
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Crystal structure of a new form of RsmD-like RNA methyl transferase from Mycobacterium tuberculosis determined at 1.74 A resolution
分子名称: Putative methyltransferase
著者Venkataraman, S, Dhankar, A, Sinha, K.M, Manivasakan, P, Iqbal, N, Singh, T.P, Prasad, B.V.L.S.
登録日2018-08-22
公開日2018-09-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystal structure of a new form of RsmD-like RNA methyl transferase from Mycobacterium tuberculosis determined at 1.74 A resolution
To Be Published
3P9N
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BU of 3p9n by Molmil
Rv2966c of M. tuberculosis is a RsmD-like methyltransferase
分子名称: ACETATE ION, POSSIBLE METHYLTRANSFERASE (METHYLASE)
著者Kumar, A, Malhotra, K, Saigal, K, Sinha, K.M, Taneja, B.
登録日2010-10-18
公開日2011-04-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and functional characterization of Rv2966c protein reveals an RsmD-like methyltransferase from Mycobacterium tuberculosis and the role of its N-terminal domain in target recognition
J.Biol.Chem., 286, 2011

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件を2024-08-14に公開中

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