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PDB: 34 results

4JIY
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BU of 4jiy by Molmil
RNA three-way junction stabilized by a supramolecular di-iron(II) cylinder drug
Descriptor: 5'-(CGUACG)-3', FE (II) ION, N-[(1E)-PYRIDIN-2-YLMETHYLENE]-N-[4-(4-{[(1E)-PYRIDIN-2-YLMETHYLENE]AMINO}BENZYL)PHENYL]AMINE
Authors:Sigel, R.K.O, Schnabl, J.A, Freisinger, E, Spingler, B, Hannon, M.J.
Deposit date:2013-03-07
Release date:2013-09-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Binding of a designed anti-cancer drug to the central cavity of an RNA three-way junction.
Angew.Chem.Int.Ed.Engl., 52, 2013
1R2P
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BU of 1r2p by Molmil
Solution structure of domain 5 from the ai5(gamma) group II intron
Descriptor: 34-MER
Authors:Sigel, R.K.O, Sashital, D.G, Abramovitz, D.L, Palmer III, A.G, Butcher, S.E, Pyle, A.M.
Deposit date:2003-09-29
Release date:2004-02-03
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of domain 5 of a group II intron ribozyme reveals a new RNA motif.
Nat.Struct.Mol.Biol., 11, 2004
6EZ0
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BU of 6ez0 by Molmil
Specific phosphorothioate substitution within domain 6 of a group II intron ribozyme leads to changes in local structure and metal ion binding
Descriptor: RNA (27-MER)
Authors:Erat, M.C, Besic, E, Oberhuber, M, Johannsen, S, Sigel, R.K.O.
Deposit date:2017-11-13
Release date:2018-01-03
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Specific phosphorothioate substitution within domain 6 of a group II intron ribozyme leads to changes in local structure and metal ion binding.
J. Biol. Inorg. Chem., 23, 2018
6RLS
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BU of 6rls by Molmil
Concerted dynamics of metallo-base pairs in an A/B-form helical transition (apo species)
Descriptor: DNA (5'-D(*CP*GP*TP*CP*TP*CP*AP*TP*GP*AP*TP*AP*CP*G)-3')_apo
Authors:Schmidt, O.P, Jurt, S, Johannsen, S, Karimi, A, Sigel, R.K.O, Luedtke, N.W.
Deposit date:2019-05-02
Release date:2019-10-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Concerted dynamics of metallo-base pairs in an A/B-form helical transition.
Nat Commun, 10, 2019
2AHT
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BU of 2aht by Molmil
Solution structure of domain 6 from the ai5(gamma)group II intron
Descriptor: 27-MER
Authors:Erat, M.C, Zerbe, O, Fox, T, Sigel, R.K.O.
Deposit date:2005-07-28
Release date:2006-10-17
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of domain 6 from a self-splicing group II intron ribozyme: a Mg(2+) binding site is located close to the stacked branch adenosine.
Chembiochem, 8, 2007
2K66
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BU of 2k66 by Molmil
NMR solution structure of the d3'-stem closed by a GAAA tetraloop of the group II intron Sc.ai5(gamma)
Descriptor: 5'-R(*GP*GP*AP*GP*UP*AP*UP*GP*UP*GP*AP*AP*AP*GP*CP*AP*UP*AP*CP*UP*CP*C)-3'
Authors:Kruschel, D, Sigel, R.K.O.
Deposit date:2008-07-04
Release date:2009-07-14
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:NMR structure of the 5' splice site in the group IIB intron Sc.ai5 gamma--conformational requirements for exon-intron recognition.
Rna, 20, 2014
4U78
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BU of 4u78 by Molmil
Octameric RNA duplex soaked in copper(II)chloride
Descriptor: CALCIUM ION, COPPER (II) ION, RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3')
Authors:Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O.
Deposit date:2014-07-30
Release date:2015-08-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016
4U47
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BU of 4u47 by Molmil
Octameric RNA duplex soaked in terbium(III)chloride
Descriptor: RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3'), TERBIUM(III) ION
Authors:Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O.
Deposit date:2014-07-23
Release date:2015-08-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.952 Å)
Cite:The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016
4U3P
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BU of 4u3p by Molmil
Octameric RNA duplex co-crystallized with strontium(II)chloride
Descriptor: RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3'), STRONTIUM ION
Authors:Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O.
Deposit date:2014-07-22
Release date:2015-07-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.866 Å)
Cite:The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016
4U3R
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BU of 4u3r by Molmil
Octameric RNA duplex co-crystallized with cobalt(II)chloride
Descriptor: COBALT (II) ION, RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3')
Authors:Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O.
Deposit date:2014-07-22
Release date:2015-07-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016
4U3L
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BU of 4u3l by Molmil
octameric RNA duplex co-crystallized in calcium(II)chloride
Descriptor: CALCIUM ION, RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3')
Authors:Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O.
Deposit date:2014-07-22
Release date:2015-07-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.482 Å)
Cite:The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016
4U3O
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BU of 4u3o by Molmil
Octameric RNA duplex soaked in manganese(II)chloride
Descriptor: MANGANESE (II) ION, RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3')
Authors:Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O.
Deposit date:2014-07-22
Release date:2015-07-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016
2K69
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BU of 2k69 by Molmil
NMR solution structure of modified DNA containing imidazole nucleosides at basic pH
Descriptor: DNA (5'-D(*DTP*DTP*DAP*DAP*DTP*DTP*DTP*(D33)P*(D33)P*(D33)P*DAP*DAP*DAP*DTP*DTP*DAP*DA)-3')
Authors:Johannsen, S, Boehme, D, Duepre, N, Mueller, J, Sigel, R.K.O.
Deposit date:2008-07-04
Release date:2009-07-07
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure at different pHs of a DNA hairpin containing artificial nucleotides
To be Published
2K68
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BU of 2k68 by Molmil
NMR solution structure of modified DNA containing imidazole nucleosides at neutral pH
Descriptor: DNA (5'-D(*DTP*DTP*DAP*DAP*DTP*DTP*DTP*(D33)P*(D33)P*(D33)P*DAP*DAP*DAP*DTP*DTP*DAP*DA)-3')
Authors:Johannsen, S, Boehme, D, Duepre, N, Mueller, J, Sigel, R.K.O.
Deposit date:2008-07-04
Release date:2009-07-07
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure at different pHs of a DNA hairpin containing artificial nucleotides
To be Published
2K65
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BU of 2k65 by Molmil
NMR solution structure of the exon/intron binding site 1 (EBS1/IBS1) of the group II intron Sc.ai5(gamma)
Descriptor: 5'-R(*CP*AP*GP*UP*GP*UP*C)-3', 5'-R(*GP*GP*CP*AP*CP*UP*G)-3'
Authors:Kruschel, D, Sigel, R.K.O.
Deposit date:2008-07-04
Release date:2009-07-14
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the 5'-splice site of a group II intron ribozyme
To be Published
7Q6L
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BU of 7q6l by Molmil
Solution structure of an intramolecular RNA G-quadruplex formed by the 6A8A17U mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto-oncogene
Descriptor: RNA (5'-R(*GP*GP*GP*CP*CP*AP*UP*AP*GP*GP*GP*UP*GP*GP*GP*AP*UP*CP*UP*GP*GP*G)-3')
Authors:Wang, Z, Jurt, S, Dominguez-Martin, A, Johannsen, S, Sigel, R.K.O.
Deposit date:2021-11-08
Release date:2022-11-16
Last modified:2024-01-31
Method:SOLUTION NMR
Cite:Solution structure of an intramolecular RNA G-quadruplex formed by the 6A8A17U mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto-oncogene
To Be Published
7Q48
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BU of 7q48 by Molmil
Solution structure of an intramolecular RNA G-quadruplex formed by the 6A8U17U mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto onco-gene
Descriptor: RNA (5'-R(*GP*GP*GP*CP*CP*AP*UP*UP*GP*GP*GP*UP*GP*GP*GP*AP*UP*CP*UP*GP*GP*G)-3')
Authors:Wang, Z, Jurt, S, Dominguez-Martin, A, Johannsen, S, Sigel, R.K.O.
Deposit date:2021-10-29
Release date:2022-11-16
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Solution structure of an intramolecular RNA G-quadruplex formed by the 6A8U17U mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto onco-gene
To Be Published
7QA2
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BU of 7qa2 by Molmil
Solution structure of an intramolecular RNA G-quadruplex formed by the 6A mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto-oncogene
Descriptor: RNA (5'-R(*GP*GP*GP*CP*CP*AP*UP*GP*GP*GP*GP*UP*GP*GP*GP*AP*GP*CP*UP*GP*GP*G)-3')
Authors:Wang, Z, Falk, T, Jurt, S, Johannsen, S, Sigel, R.K.O.
Deposit date:2021-11-15
Release date:2022-11-23
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Solution structure of an intramolecular RNA G-quadruplex formed by the 6A mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto-oncogene
To Be Published
6FY6
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BU of 6fy6 by Molmil
Concerted dynamics of metallo-base pairs in an A/B-form helical transition (major species)
Descriptor: DNA (5'-D(*CP*GP*TP*CP*TP*CP*AP*TP*GP*AP*TP*AP*CP*G)-3')_major, MERCURY (II) ION
Authors:Schmidt, O.P, Jurt, S, Johannsen, S, Karimi, A, Sigel, R.K.O, Luedtke, N.W.
Deposit date:2018-03-11
Release date:2019-10-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Concerted dynamics of metallo-base pairs in an A/B-form helical transition.
Nat Commun, 10, 2019
6FY7
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BU of 6fy7 by Molmil
Concerted dynamics of metallo-base pairs in an A/B-form helical transition (minor species)
Descriptor: DNA (5'-D(*CP*GP*TP*CP*TP*CP*AP*TP*GP*AP*TP*AP*CP*G)-3')_minor, MERCURY (II) ION
Authors:Schmidt, O.P, Jurt, S, Johannsen, S, Karimi, A, Sigel, R.K.O, Luedtke, N.W.
Deposit date:2018-03-11
Release date:2019-10-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Concerted dynamics of metallo-base pairs in an A/B-form helical transition.
Nat Commun, 10, 2019
6GN4
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BU of 6gn4 by Molmil
tc-DNA/tc-DNA duplex
Descriptor: Tc-DNA (5'-D(*(TCJ)P*(TTK)P*(TCJ)P*(TCS)P*(TCS)P*(TCJ)P*(TTK)P*(TTK)P*(TCY)P*(TCJ))-3'), Tc-DNA (5'-D(*(TCS)P*(TTK)P*(TCY)P*(TCY)P*(TCS)P*(TCJ)P*(TCJ)P*(TCS)P*(TCY)P*(TCS))-3')
Authors:Istrate, A, Johannsen, S, Istrate, A, Sigel, R.K.O, Leumann, C.
Deposit date:2018-05-29
Release date:2018-06-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance.
Nucleic Acids Res., 47, 2019
6GMY
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BU of 6gmy by Molmil
Tc-DNA/RNA duplex
Descriptor: RNA (5'-R(*GP*UP*AP*AP*GP*CP*CP*GP*AP*G)-3'), Tc-DNA (5'-(*(TCJ)P*(TTK)P*(TCJ)P*(TCS)P*(TCS)P*(TCJ)P*(TTK)P*(TTK)P*(TCY)P*(TCJ))-3')
Authors:Istrate, A, Johannsen, S, Istrate, A, Sigel, R.K.O, Leumann, C.
Deposit date:2018-05-28
Release date:2018-06-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance.
Nucleic Acids Res., 47, 2019
6GPI
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BU of 6gpi by Molmil
Tc-DNA/DNA duplex
Descriptor: DNA (5'-D(*GP*TP*AP*AP*GP*CP*CP*GP*AP*G)-3'), tc-DNA (5'-D(*(TCJ)P*(TTK)P*(TCJ)P*(TCS)P*(TCS)P*(TCJ)P*(TTK)P*(TTK)P*(TCY)P*(TCJ))-3')
Authors:Istrate, A, Johannsen, S, Istrate, A, Sigel, R.K.O, Leumann, C.
Deposit date:2018-06-05
Release date:2018-06-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance.
Nucleic Acids Res., 47, 2019
7QR4
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BU of 7qr4 by Molmil
human CPEB3 HDV-like ribozyme
Descriptor: RNA CPEB3 ribozyme, U1 small nuclear ribonucleoprotein A
Authors:Przytula-Mally, A.I, Engilberge, S, Johannsen, S, Olieric, V, Masquida, B, Sigel, R.K.O.
Deposit date:2022-01-17
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Anticodon-like loop-mediated dimerization in the crystal structures of HdV-like CPEB3 ribozymes
Biorxiv, 2022
7QR3
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BU of 7qr3 by Molmil
Chimpanzee CPEB3 HDV-like ribozyme
Descriptor: GLYCEROL, POTASSIUM ION, U1 small nuclear ribonucleoprotein A, ...
Authors:Przytula-Mally, A.I, Engilberge, S, Johannsen, S, Olieric, V, Masquida, B, Sigel, R.K.O.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Anticodon-like loop-mediated dimerization in the crystal structures of HdV-like CPEB3 ribozymes
Biorxiv, 2022

 

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