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PDB: 35 件

4JIY
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RNA three-way junction stabilized by a supramolecular di-iron(II) cylinder drug
分子名称: 5'-(CGUACG)-3', FE (II) ION, N-[(1E)-PYRIDIN-2-YLMETHYLENE]-N-[4-(4-{[(1E)-PYRIDIN-2-YLMETHYLENE]AMINO}BENZYL)PHENYL]AMINE
著者Sigel, R.K.O, Schnabl, J.A, Freisinger, E, Spingler, B, Hannon, M.J.
登録日2013-03-07
公開日2013-09-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Binding of a designed anti-cancer drug to the central cavity of an RNA three-way junction.
Angew.Chem.Int.Ed.Engl., 52, 2013
1R2P
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BU of 1r2p by Molmil
Solution structure of domain 5 from the ai5(gamma) group II intron
分子名称: 34-MER
著者Sigel, R.K.O, Sashital, D.G, Abramovitz, D.L, Palmer III, A.G, Butcher, S.E, Pyle, A.M.
登録日2003-09-29
公開日2004-02-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of domain 5 of a group II intron ribozyme reveals a new RNA motif.
Nat.Struct.Mol.Biol., 11, 2004
6EZ0
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BU of 6ez0 by Molmil
Specific phosphorothioate substitution within domain 6 of a group II intron ribozyme leads to changes in local structure and metal ion binding
分子名称: RNA (27-MER)
著者Erat, M.C, Besic, E, Oberhuber, M, Johannsen, S, Sigel, R.K.O.
登録日2017-11-13
公開日2018-01-03
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Specific phosphorothioate substitution within domain 6 of a group II intron ribozyme leads to changes in local structure and metal ion binding.
J. Biol. Inorg. Chem., 23, 2018
6RLS
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BU of 6rls by Molmil
Concerted dynamics of metallo-base pairs in an A/B-form helical transition (apo species)
分子名称: DNA (5'-D(*CP*GP*TP*CP*TP*CP*AP*TP*GP*AP*TP*AP*CP*G)-3')_apo
著者Schmidt, O.P, Jurt, S, Johannsen, S, Karimi, A, Sigel, R.K.O, Luedtke, N.W.
登録日2019-05-02
公開日2019-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Concerted dynamics of metallo-base pairs in an A/B-form helical transition.
Nat Commun, 10, 2019
2AHT
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BU of 2aht by Molmil
Solution structure of domain 6 from the ai5(gamma)group II intron
分子名称: 27-MER
著者Erat, M.C, Zerbe, O, Fox, T, Sigel, R.K.O.
登録日2005-07-28
公開日2006-10-17
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of domain 6 from a self-splicing group II intron ribozyme: a Mg(2+) binding site is located close to the stacked branch adenosine.
Chembiochem, 8, 2007
2K66
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BU of 2k66 by Molmil
NMR solution structure of the d3'-stem closed by a GAAA tetraloop of the group II intron Sc.ai5(gamma)
分子名称: 5'-R(*GP*GP*AP*GP*UP*AP*UP*GP*UP*GP*AP*AP*AP*GP*CP*AP*UP*AP*CP*UP*CP*C)-3'
著者Kruschel, D, Sigel, R.K.O.
登録日2008-07-04
公開日2009-07-14
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR structure of the 5' splice site in the group IIB intron Sc.ai5 gamma--conformational requirements for exon-intron recognition.
Rna, 20, 2014
2KE8
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BU of 2ke8 by Molmil
NMR solution structure of metal-modified DNA
分子名称: DNA (5'-D(*TP*TP*AP*AP*TP*TP*TP*(D33)P*(D33)P*(D33)P*AP*AP*AP*TP*TP*AP*A)-3'), SILVER ION
著者Johannsen, S, Duepre, N, Boehme, D, Mueller, J, Sigel, R.K.O.
登録日2009-01-27
公開日2010-02-09
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of a DNA double helix with consecutive metal-mediated base pairs.
Nat.Chem., 2, 2010
4U3O
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BU of 4u3o by Molmil
Octameric RNA duplex soaked in manganese(II)chloride
分子名称: MANGANESE (II) ION, RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3')
著者Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O.
登録日2014-07-22
公開日2015-07-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016
4U3L
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octameric RNA duplex co-crystallized in calcium(II)chloride
分子名称: CALCIUM ION, RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3')
著者Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O.
登録日2014-07-22
公開日2015-07-29
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.482 Å)
主引用文献The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016
4U78
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Octameric RNA duplex soaked in copper(II)chloride
分子名称: CALCIUM ION, COPPER (II) ION, RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3')
著者Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O.
登録日2014-07-30
公開日2015-08-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016
4U47
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Octameric RNA duplex soaked in terbium(III)chloride
分子名称: RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3'), TERBIUM(III) ION
著者Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O.
登録日2014-07-23
公開日2015-08-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.952 Å)
主引用文献The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016
4U3P
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BU of 4u3p by Molmil
Octameric RNA duplex co-crystallized with strontium(II)chloride
分子名称: RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3'), STRONTIUM ION
著者Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O.
登録日2014-07-22
公開日2015-07-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.866 Å)
主引用文献The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016
4U3R
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BU of 4u3r by Molmil
Octameric RNA duplex co-crystallized with cobalt(II)chloride
分子名称: COBALT (II) ION, RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3')
著者Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O.
登録日2014-07-22
公開日2015-07-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016
6FY6
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BU of 6fy6 by Molmil
Concerted dynamics of metallo-base pairs in an A/B-form helical transition (major species)
分子名称: DNA (5'-D(*CP*GP*TP*CP*TP*CP*AP*TP*GP*AP*TP*AP*CP*G)-3')_major, MERCURY (II) ION
著者Schmidt, O.P, Jurt, S, Johannsen, S, Karimi, A, Sigel, R.K.O, Luedtke, N.W.
登録日2018-03-11
公開日2019-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Concerted dynamics of metallo-base pairs in an A/B-form helical transition.
Nat Commun, 10, 2019
2K69
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BU of 2k69 by Molmil
NMR solution structure of modified DNA containing imidazole nucleosides at basic pH
分子名称: DNA (5'-D(*DTP*DTP*DAP*DAP*DTP*DTP*DTP*(D33)P*(D33)P*(D33)P*DAP*DAP*DAP*DTP*DTP*DAP*DA)-3')
著者Johannsen, S, Boehme, D, Duepre, N, Mueller, J, Sigel, R.K.O.
登録日2008-07-04
公開日2009-07-07
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure at different pHs of a DNA hairpin containing artificial nucleotides
To be Published
6FY7
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BU of 6fy7 by Molmil
Concerted dynamics of metallo-base pairs in an A/B-form helical transition (minor species)
分子名称: DNA (5'-D(*CP*GP*TP*CP*TP*CP*AP*TP*GP*AP*TP*AP*CP*G)-3')_minor, MERCURY (II) ION
著者Schmidt, O.P, Jurt, S, Johannsen, S, Karimi, A, Sigel, R.K.O, Luedtke, N.W.
登録日2018-03-11
公開日2019-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Concerted dynamics of metallo-base pairs in an A/B-form helical transition.
Nat Commun, 10, 2019
2K68
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BU of 2k68 by Molmil
NMR solution structure of modified DNA containing imidazole nucleosides at neutral pH
分子名称: DNA (5'-D(*DTP*DTP*DAP*DAP*DTP*DTP*DTP*(D33)P*(D33)P*(D33)P*DAP*DAP*DAP*DTP*DTP*DAP*DA)-3')
著者Johannsen, S, Boehme, D, Duepre, N, Mueller, J, Sigel, R.K.O.
登録日2008-07-04
公開日2009-07-07
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure at different pHs of a DNA hairpin containing artificial nucleotides
To be Published
2K65
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BU of 2k65 by Molmil
NMR solution structure of the exon/intron binding site 1 (EBS1/IBS1) of the group II intron Sc.ai5(gamma)
分子名称: 5'-R(*CP*AP*GP*UP*GP*UP*C)-3', 5'-R(*GP*GP*CP*AP*CP*UP*G)-3'
著者Kruschel, D, Sigel, R.K.O.
登録日2008-07-04
公開日2009-07-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the 5'-splice site of a group II intron ribozyme
To be Published
2K67
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BU of 2k67 by Molmil
NMR solution structure of modified DNA containing imidazole nucleosides at acidic pH
分子名称: DNA (5'-D(*DTP*DTP*DAP*DAP*DTP*DTP*DTP*(D33)P*(D33)P*(D33)P*DAP*DAP*DAP*DTP*DTP*DAP*DA)-3')
著者Johannsen, S, Boehme, D, Duepre, N, Mueller, J, Sigel, R.K.O.
登録日2008-07-04
公開日2009-07-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure at different pHs of a DNA hairpin containing artificial nucleotides
To be Published
6GN4
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BU of 6gn4 by Molmil
tc-DNA/tc-DNA duplex
分子名称: Tc-DNA (5'-D(*(TCJ)P*(TTK)P*(TCJ)P*(TCS)P*(TCS)P*(TCJ)P*(TTK)P*(TTK)P*(TCY)P*(TCJ))-3'), Tc-DNA (5'-D(*(TCS)P*(TTK)P*(TCY)P*(TCY)P*(TCS)P*(TCJ)P*(TCJ)P*(TCS)P*(TCY)P*(TCS))-3')
著者Istrate, A, Johannsen, S, Istrate, A, Sigel, R.K.O, Leumann, C.
登録日2018-05-29
公開日2018-06-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance.
Nucleic Acids Res., 47, 2019
6GMY
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BU of 6gmy by Molmil
Tc-DNA/RNA duplex
分子名称: RNA (5'-R(*GP*UP*AP*AP*GP*CP*CP*GP*AP*G)-3'), Tc-DNA (5'-(*(TCJ)P*(TTK)P*(TCJ)P*(TCS)P*(TCS)P*(TCJ)P*(TTK)P*(TTK)P*(TCY)P*(TCJ))-3')
著者Istrate, A, Johannsen, S, Istrate, A, Sigel, R.K.O, Leumann, C.
登録日2018-05-28
公開日2018-06-13
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance.
Nucleic Acids Res., 47, 2019
6GPI
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BU of 6gpi by Molmil
Tc-DNA/DNA duplex
分子名称: DNA (5'-D(*GP*TP*AP*AP*GP*CP*CP*GP*AP*G)-3'), tc-DNA (5'-D(*(TCJ)P*(TTK)P*(TCJ)P*(TCS)P*(TCS)P*(TCJ)P*(TTK)P*(TTK)P*(TCY)P*(TCJ))-3')
著者Istrate, A, Johannsen, S, Istrate, A, Sigel, R.K.O, Leumann, C.
登録日2018-06-05
公開日2018-06-13
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance.
Nucleic Acids Res., 47, 2019
2M23
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BU of 2m23 by Molmil
NMR solution structure of the d3'-hairpin of the group II intron Sc.ai5gamma including EBS1 bound to IBS1
分子名称: RNA (29-MER), RNA_(5'-R(*CP*AP*GP*UP*GP*UP*C)-3')_
著者Kruschel, D, Skilandat, M, Sigel, R.K.O.
登録日2012-12-12
公開日2013-12-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure of the 5' splice site in the group IIB intron Sc.ai5 gamma--conformational requirements for exon-intron recognition.
Rna, 20, 2014
2M5U
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BU of 2m5u by Molmil
NMR structure of the P4 hairpin of the CPEB3 ribozyme
分子名称: RNA_(5'-R(*GP*GP*CP*AP*GP*AP*UP*UP*CP*UP*GP*GP*UP*GP*AP*AP*UP*CP*UP*GP*CP*C)-3')
著者Skilandat, M, Rowinska-Zyrek, M, Sigel, R.K.O.
登録日2013-03-08
公開日2014-04-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure and metal ion binding sites of the human CPEB3 ribozyme's P4 domain.
J.Biol.Inorg.Chem., 19, 2014
2M1V
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BU of 2m1v by Molmil
NMR solution structure of the d3'-hairpin from the Sc.ai5gamma group II intron including the EBS1:dIBS1 RNA:DNA hybrid
分子名称: DNA_(5'-D(*CP*AP*GP*TP*GP*TP*C)-3')_, RNA (29-MER)
著者Skilandat, M, Sigel, R.K.O.
登録日2012-12-07
公開日2014-06-11
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The Role of Mg(II) in DNA Cleavage Site Recognition in Group II Intron Ribozymes: SOLUTION STRUCTURE AND METAL ION BINDING SITES OF THE RNADNA COMPLEX.
J.Biol.Chem., 289, 2014

 

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件を2024-08-07に公開中

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