6GPI
Tc-DNA/DNA duplex
Summary for 6GPI
Entry DOI | 10.2210/pdb6gpi/pdb |
NMR Information | BMRB: 34280 |
Descriptor | tc-DNA (5'-D(*(TCJ)P*(TTK)P*(TCJ)P*(TCS)P*(TCS)P*(TCJ)P*(TTK)P*(TTK)P*(TCY)P*(TCJ))-3'), DNA (5'-D(*GP*TP*AP*AP*GP*CP*CP*GP*AP*G)-3') (2 entities in total) |
Functional Keywords | tricyclo-dna, modified nucleic acids, modified oligonucleotide, tc-dna, dna-rna hybrid |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 6446.62 |
Authors | Istrate, A.,Johannsen, S.,Istrate, A.,Sigel, R.K.O.,Leumann, C. (deposition date: 2018-06-05, release date: 2018-06-13, Last modification date: 2024-05-15) |
Primary citation | Istrate, A.,Johannsen, S.,Istrate, A.,Sigel, R.K.O.,Leumann, C.J. NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance. Nucleic Acids Res., 47:4872-4882, 2019 Cited by PubMed: 30916334DOI: 10.1093/nar/gkz197 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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