Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 263 results
1JWV
DownloadVisualize
BU of 1jwv by Molmil
Crystal structure of G238A mutant of TEM-1 beta-lactamase in complex with a boronic acid inhibitor (sefb4)
Descriptor: BETA-LACTAMASE TEM, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE, POTASSIUM ION
Authors:Wang, X, Minasov, G, Shoichet, B.K.
Deposit date:2001-09-05
Release date:2002-06-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs.
J.Mol.Biol., 320, 2002
1JWP
DownloadVisualize
BU of 1jwp by Molmil
Structure of M182T mutant of TEM-1 beta-lactamase
Descriptor: BETA-LACTAMASE TEM, PHOSPHATE ION
Authors:Wang, X, Minasov, G, Shoichet, B.K.
Deposit date:2001-09-04
Release date:2002-06-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs.
J.Mol.Biol., 320, 2002
1KE0
DownloadVisualize
BU of 1ke0 by Molmil
X-ray crystal structure of AmpC beta-lactamase from E. coli in complex with the inhibitor 4-(carboxyvin-2-yl)phenylboronic acid
Descriptor: 4-(CARBOXYVIN-2-YL)PHENYLBORONIC ACID, PHOSPHATE ION, beta-lactamase
Authors:Powers, R.A, Shoichet, B.K.
Deposit date:2001-11-13
Release date:2002-07-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-based approach for binding site identification on AmpC beta-lactamase.
J.Med.Chem., 45, 2002
1KE3
DownloadVisualize
BU of 1ke3 by Molmil
X-ray crystal structure of AmpC beta-lactamase from E. coli in complex with the inhibitor 4,4'-biphenyldiboronic acid
Descriptor: 4,4'-BIPHENYLDIBORONIC ACID, PHOSPHATE ION, beta-lactamase
Authors:Powers, R.A, Shoichet, B.K.
Deposit date:2001-11-14
Release date:2002-07-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure-based approach for binding site identification on AmpC beta-lactamase.
J.Med.Chem., 45, 2002
1KDW
DownloadVisualize
BU of 1kdw by Molmil
X-ray crystal structure of AmpC beta-lactamase from E. coli in complex with the inhibitor 4-carboxyphenylboronic acid
Descriptor: 4-CARBOXYPHENYLBORONIC ACID, PHOSPHATE ION, beta-lactamase
Authors:Powers, R.A, Shoichet, B.K.
Deposit date:2001-11-13
Release date:2002-07-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structure-based approach for binding site identification on AmpC beta-lactamase.
J.Med.Chem., 45, 2002
1KDS
DownloadVisualize
BU of 1kds by Molmil
X-ray crystal structure of AmpC beta-lactamase from E. coli in complex with the inhibitor 3-nitrophenylboronic acid
Descriptor: 3-NITROPHENYLBORONIC ACID, BETA-LACTAMASE
Authors:Powers, R.A, Shoichet, B.K.
Deposit date:2001-11-13
Release date:2002-07-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure-based approach for binding site identification on AmpC beta-lactamase.
J.Med.Chem., 45, 2002
1KVL
DownloadVisualize
BU of 1kvl by Molmil
X-ray Crystal Structure of AmpC S64G Mutant beta-Lactamase in Complex with Substrate and Product Forms of Cephalothin
Descriptor: 2-[CARBOXY-(2-THIOPHEN-2-YL-ACETYLAMINO)-METHYL]-5-METHYL-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, 2-[CARBOXY-(2-THIOPHEN-2-YL-ACETYLAMINO)-METHYL]-5-METHYLENE-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase, ...
Authors:Beadle, B.M, Trehan, I, Focia, P.J, Shoichet, B.K.
Deposit date:2002-01-27
Release date:2002-03-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Structural milestones in the reaction pathway of an amide hydrolase: substrate, acyl, and product complexes of cephalothin with AmpC beta-lactamase.
Structure, 10, 2002
1KVM
DownloadVisualize
BU of 1kvm by Molmil
X-ray Crystal Structure of AmpC WT beta-Lactamase in Complex with Covalently Bound Cephalothin
Descriptor: 5-METHYLENE-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, PHOSPHATE ION, beta-lactamase
Authors:Beadle, B.M, Trehan, I, Focia, P.J, Shoichet, B.K.
Deposit date:2002-01-27
Release date:2002-03-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural milestones in the reaction pathway of an amide hydrolase: substrate, acyl, and product complexes of cephalothin with AmpC beta-lactamase.
Structure, 10, 2002
1KE4
DownloadVisualize
BU of 1ke4 by Molmil
X-ray crystal structure of AmpC beta-lactamase from E. coli
Descriptor: PHOSPHATE ION, beta-lactamase
Authors:Powers, R.A, Shoichet, B.K.
Deposit date:2001-11-14
Release date:2002-07-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structure-based approach for binding site identification on AmpC beta-lactamase.
J.Med.Chem., 45, 2002
1LGW
DownloadVisualize
BU of 1lgw by Molmil
T4 Lysozyme Mutant L99A/M102Q Bound by 2-fluoroaniline
Descriptor: 2-FLUOROANILINE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:2002-04-16
Release date:2002-05-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A Model Binding Site for Testing Scoring Functions in Molecular Docking
J.Mol.Biol., 322, 2002
1LL9
DownloadVisualize
BU of 1ll9 by Molmil
Crystal Structure Of AmpC beta-Lactamase From E. Coli In Complex With Amoxicillin
Descriptor: 2-{1-[2-AMINO-2-(4-HYDROXY-PHENYL)-ACETYLAMINO]-2-OXO-ETHYL}-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID, beta-lactamase
Authors:Trehan, I, Morandi, F, Blaszczak, L.C, Shoichet, B.K.
Deposit date:2002-04-26
Release date:2002-10-02
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Using steric hindrance to design new inhibitors of class C beta-lactamases.
Chem.Biol., 9, 2002
1L0G
DownloadVisualize
BU of 1l0g by Molmil
X-ray Crystal Structure of AmpC S64G Mutant beta-Lactamase
Descriptor: PHOSPHATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, beta-lactamase
Authors:Beadle, B.M, Shoichet, B.K.
Deposit date:2002-02-09
Release date:2002-08-14
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural bases of stability-function tradeoffs in enzymes.
J.Mol.Biol., 321, 2002
1LGU
DownloadVisualize
BU of 1lgu by Molmil
T4 Lysozyme Mutant L99A/M102Q
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme
Authors:Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:2002-04-16
Release date:2002-05-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Model Binding Site for Testing Scoring Functions in Molecular Docking
J.Mol.Biol., 322, 2002
1LLB
DownloadVisualize
BU of 1llb by Molmil
Crystal Structure Of AmpC beta-Lactamase From E. Coli In Complex With ATMO-penicillin
Descriptor: 2-{1-[2-(2-AMINO-THIAZOL-4-YL)-2-METHOXYIMINO-ACETYLAMINO]-2-OXO-ETHYL}-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID, beta-lactamase
Authors:Trehan, I, Morandi, F, Blaszczak, L.C, Shoichet, B.K.
Deposit date:2002-04-26
Release date:2002-10-02
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Using steric hindrance to design new inhibitors of class C beta-lactamases.
Chem.Biol., 9, 2002
1LL5
DownloadVisualize
BU of 1ll5 by Molmil
X-ray crystal structure of AmpC WT beta-lactamase in complex with covalently bound imipenem
Descriptor: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, beta-lactamase
Authors:Beadle, B.M, Shoichet, B.K.
Deposit date:2002-04-26
Release date:2002-11-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for Imipenem Inhibition of Class C beta-lactamases
ANTIMICROB.AGENTS CHEMOTHER., 46, 2002
1LI0
DownloadVisualize
BU of 1li0 by Molmil
Crystal structure of TEM-32 beta-Lactamase at 1.6 Angstrom
Descriptor: BICARBONATE ION, Class A beta-Lactamase- TEM-32, POTASSIUM ION
Authors:Wang, X, Minasov, G, Shoichet, B.K.
Deposit date:2002-04-17
Release date:2002-09-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:The structural bases of antibiotic resistance in the clinically derived mutant beta-lactamases TEM-30, TEM-32, and TEM-34.
J.Biol.Chem., 277, 2002
1L0D
DownloadVisualize
BU of 1l0d by Molmil
X-ray Crystal Structure of AmpC S64D Mutant beta-Lactamase
Descriptor: PHOSPHATE ION, beta-lactamase
Authors:Beadle, B.M, Shoichet, B.K.
Deposit date:2002-02-09
Release date:2002-08-14
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Structural bases of stability-function tradeoffs in enzymes.
J.Mol.Biol., 321, 2002
1L2S
DownloadVisualize
BU of 1l2s by Molmil
X-ray crystal structure of AmpC beta-lactamase from E. coli in complex with a DOCK-predicted non-covalent inhibitor
Descriptor: 3-[(4-CHLOROANILINO)SULFONYL]THIOPHENE-2-CARBOXYLIC ACID, beta-lactamase
Authors:Powers, R.A, Morandi, F, Shoichet, B.K.
Deposit date:2002-02-24
Release date:2002-07-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase.
Structure, 10, 2002
1L0F
DownloadVisualize
BU of 1l0f by Molmil
X-ray Crystal Structure of AmpC N152H Mutant beta-Lactamase
Descriptor: PHOSPHATE ION, beta-lactamase
Authors:Beadle, B.M, Shoichet, B.K.
Deposit date:2002-02-09
Release date:2002-08-14
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural bases of stability-function tradeoffs in enzymes.
J.Mol.Biol., 321, 2002
1LGX
DownloadVisualize
BU of 1lgx by Molmil
T4 Lysozyme Mutant L99A/M102Q Bound by 3,5-difluoroaniline
Descriptor: 3,5-DIFLUOROANILINE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:2002-04-16
Release date:2002-05-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Model Binding Site for Testing Scoring Functions in Molecular Docking
J.Mol.Biol., 322, 2002
1LHY
DownloadVisualize
BU of 1lhy by Molmil
Crystal structure of TEM-30 beta-Lactamase at 2.0 Angstrom
Descriptor: Class A beta-Lactamase- TEM 30, PHOSPHATE ION
Authors:Wang, X, Minasov, G, Shoichet, B.K.
Deposit date:2002-04-17
Release date:2002-09-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structural bases of antibiotic resistance in the clinically derived mutant beta-lactamases TEM-30, TEM-32, and TEM-34.
J.Biol.Chem., 277, 2002
1L0E
DownloadVisualize
BU of 1l0e by Molmil
X-ray Crystal Structure of AmpC K67Q Mutant beta-Lactamase
Descriptor: PHOSPHATE ION, beta-lactamase
Authors:Beadle, B.M, Shoichet, B.K.
Deposit date:2002-02-09
Release date:2002-08-14
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural bases of stability-function tradeoffs in enzymes.
J.Mol.Biol., 321, 2002
1LI3
DownloadVisualize
BU of 1li3 by Molmil
T4 lysozyme mutant L99A/M102Q bound by 3-chlorophenol
Descriptor: 3-CHLOROPHENOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:2002-04-17
Release date:2002-05-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A Model Binding Site for Testing Scoring Functions in Molecular Docking
J.Mol.Biol., 322, 2002
1LI6
DownloadVisualize
BU of 1li6 by Molmil
T4 lysozyme mutant L99A/M102Q bound by 5-methylpyrrole
Descriptor: 5-METHYLPYRROLE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:2002-04-17
Release date:2002-05-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Model Binding Site for Testing Scoring Functions in Molecular Docking
J.Mol.Biol., 322, 2002
1LI2
DownloadVisualize
BU of 1li2 by Molmil
T4 Lysozyme Mutant L99A/M102Q Bound by Phenol
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme, ...
Authors:Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:2002-04-17
Release date:2002-05-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Model Binding Site for Testing Scoring Functions in Molecular Docking
J.Mol.Biol., 322, 2002

220472

건을2024-05-29부터공개중

PDB statisticsPDBj update infoContact PDBjnumon