1L2S
X-ray crystal structure of AmpC beta-lactamase from E. coli in complex with a DOCK-predicted non-covalent inhibitor
Summary for 1L2S
| Entry DOI | 10.2210/pdb1l2s/pdb |
| Descriptor | beta-lactamase, 3-[(4-CHLOROANILINO)SULFONYL]THIOPHENE-2-CARBOXYLIC ACID (3 entities in total) |
| Functional Keywords | beta-lactamase-inhibitor complex, cephalosporinase, hydrolase |
| Biological source | Escherichia coli |
| Cellular location | Periplasm: P00811 |
| Total number of polymer chains | 2 |
| Total formula weight | 80129.15 |
| Authors | Powers, R.A.,Morandi, F.,Shoichet, B.K. (deposition date: 2002-02-24, release date: 2002-07-17, Last modification date: 2023-08-16) |
| Primary citation | Powers, R.A.,Morandi, F.,Shoichet, B.K. Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase. Structure, 10:1013-1023, 2002 Cited by PubMed: 12121656DOI: 10.1016/S0969-2126(02)00799-2 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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