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PDB: 17 件
1HIQ
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PARADOXICAL STRUCTURE AND FUNCTION IN A MUTANT HUMAN INSULIN ASSOCIATED WITH DIABETES MELLITUS
分子名称: INSULIN
著者Hua, Q.X, Shoelson, S.E, Inouye, K, Weiss, M.A.
登録日1993-03-05
公開日1994-01-31
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Paradoxical structure and function in a mutant human insulin associated with diabetes mellitus.
Proc.Natl.Acad.Sci.USA, 90, 1993
2PLE
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BU of 2ple by Molmil
NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE
分子名称: PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF
著者Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D.
登録日1994-08-19
公開日1995-01-26
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide.
Cell(Cambridge,Mass.), 77, 1994
2PLD
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NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE
分子名称: PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF
著者Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D.
登録日1994-08-19
公開日1995-01-26
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide.
Cell(Cambridge,Mass.), 77, 1994
2SHP
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TYROSINE PHOSPHATASE SHP-2
分子名称: DODECANE-TRIMETHYLAMINE, SHP-2
著者Hof, P, Pluskey, S, Dhe-Paganon, S, Eck, M.J, Shoelson, S.E.
登録日1997-12-01
公開日1999-02-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the tyrosine phosphatase SHP-2.
Cell(Cambridge,Mass.), 92, 1998
4FZ5
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Crystal Structure of Human TIRAP TIR-domain
分子名称: Toll/interleukin-1 receptor domain-containing adapter protein
著者Woo, J.R, Kim, S, Shoelson, S.E, Park, S.
登録日2012-07-06
公開日2013-05-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献X-ray Crystallographic Structure of TIR-Domain from the Human TIR-Domain Containing Adaptor Protein/MyD88 Adaptor-Like Protein (TIRAP/MAL)
Bull.Korean Chem.Soc., 33, 2013
3QYB
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X-ray Crystal Structure of Human TBC1D4 (AS160) RabGAP domain
分子名称: TBC1 domain family member 4
著者Park, S.Y, Shoelson, S.E.
登録日2011-03-03
公開日2011-03-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structures of human TBC1D1 and TBC1D4 (AS160) RabGTPase-activating protein (RabGAP) domains reveal critical elements for GLUT4 translocation.
J.Biol.Chem., 286, 2011
3QYE
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Crystal Structure of Human TBC1D1 RabGAP domain
分子名称: TBC1 domain family member 1
著者Park, S.Y, Shoelson, S.E.
登録日2011-03-03
公開日2011-03-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of human TBC1D1 and TBC1D4 (AS160) RabGTPase-activating protein (RabGAP) domains reveal critical elements for GLUT4 translocation.
J.Biol.Chem., 286, 2011
1EKG
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MATURE HUMAN FRATAXIN
分子名称: FRATAXIN
著者Dhe-Paganon, S, Shigeta, R, Chi, Y.I, Ristow, M, Shoelson, S.E.
登録日2000-03-08
公開日2000-11-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of human frataxin.
J.Biol.Chem., 275, 2000
1IRS
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IRS-1 PTB DOMAIN COMPLEXED WITH A IL-4 RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: IL-4 RECEPTOR PHOSPHOPEPTIDE, IRS-1
著者Zhou, M.-M, Huang, B, Olejniczak, E.T, Meadows, R.P, Shuker, S.B, Miyazaki, M, Trub, T, Shoelson, S.E, Feisk, S.W.
登録日1996-03-22
公開日1997-05-15
最終更新日2024-10-09
実験手法SOLUTION NMR
主引用文献Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain.
Nat.Struct.Biol., 3, 1996
2IUH
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Crystal structure of the PI3-kinase p85 N-terminal SH2 domain in complex with c-Kit phosphotyrosyl peptide
分子名称: C-KIT PHOSPHOTYROSYL PEPTIDE, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT
著者Nolte, R.T, Eck, M.J, Schlessinger, J, Shoelson, S.E, Harrison, S.C.
登録日2006-06-03
公開日2006-06-06
最終更新日2021-04-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Pi 3-Kinase P85 Amino-Terminal Sh2 Domain and its Phosphopeptide Complexes
Nat.Struct.Biol., 3, 1996
2IUG
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Crystal structure of the PI3-kinase p85 N-terminal SH2 domain
分子名称: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT
著者Nolte, R.T, Eck, M.J, Schlessinger, J, Shoelson, S.E, Harrison, S.C.
登録日2006-06-03
公開日2006-06-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystal Structure of the Pi 3-Kinase P85 Amino-Terminal Sh2 Domain and its Phosphopeptide Complexes
Nat.Struct.Biol., 3, 1996
2IUI
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Crystal structure of the PI3-kinase p85 N-terminal SH2 domain in complex with PDGFR phosphotyrosyl peptide
分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, Platelet-derived growth factor receptor beta
著者Nolte, R.T, Eck, M.J, Schlessinger, J, Shoelson, S.E, Harrison, S.C.
登録日2006-06-03
公開日2006-06-06
最終更新日2021-04-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of the Pi 3-Kinase P85 Amino- Terminal Sh2 Domain and its Phosphopeptide Complexes
Nat.Struct.Biol., 3, 1996
1Q2H
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Phenylalanine Zipper Mediates APS Dimerization
分子名称: adaptor protein with pleckstrin homology and src homology 2 domains
著者Dhe-Paganon, S, Werner, E.D, Nishi, M, Chi, Y.-I, Shoelson, S.E.
登録日2003-07-24
公開日2004-08-03
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A phenylalanine zipper mediates APS dimerization.
Nat.Struct.Mol.Biol., 11, 2004
1QQG
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CRYSTAL STRUCTURE OF THE PH-PTB TARGETING REGION OF IRS-1
分子名称: INSULIN RECEPTOR SUBSTRATE 1
著者Dhe-Paganon, S, Shoelson, S.E.
登録日1999-06-04
公開日1999-08-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1.
Proc.Natl.Acad.Sci.USA, 96, 1999
1IFR
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Structure of Lamin A/C Globular Domain
分子名称: GLYCEROL, Lamin A/C
著者Dhe-Paganon, S, Werner, E.D, Shoelson, S.E.
登録日2001-04-13
公開日2002-07-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of the globular tail of nuclear lamin.
J.Biol.Chem., 277, 2002
1IC8
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HEPATOCYTE NUCLEAR FACTOR 1A BOUND TO DNA : MODY3 GENE PRODUCT
分子名称: 5'-D(*CP*TP*TP*GP*GP*TP*TP*AP*AP*TP*AP*AP*TP*TP*CP*AP*CP*CP*AP*GP*A)-3', 5'-D(*TP*CP*TP*GP*GP*TP*GP*AP*AP*TP*TP*AP*TP*TP*AP*AP*CP*CP*AP*AP*G)-3', HEPATOCYTE NUCLEAR FACTOR 1-ALPHA
著者Chi, Y.-I, Frantz, J.D, Oh, B.-C, Hansen, L, Dhe-Paganon, S, Shoelson, S.E.
登録日2001-03-30
公開日2002-11-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Diabetes mutations delineate an atypical POU domains in HNF1-Alpha
Mol.Cell, 10, 2002
1M7W
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HNF4a ligand binding domain with bound fatty acid
分子名称: Hepatocyte nuclear factor 4-alpha, LAURIC ACID
著者Dhe-Paganon, S, Duda, K, Iwamoto, M, Chi, Y.I, Shoelson, S.E.
登録日2002-07-22
公開日2003-07-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand
J.Biol.Chem., 277, 2002

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