8JDK
| Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2023-05-14 | Release date: | 2023-12-06 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.26 Å) | Cite: | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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8JDJ
| Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2023-05-14 | Release date: | 2023-12-06 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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5ZEA
| Crystal structure of the nucleotide-free mutant A3B3 | Descriptor: | GLYCEROL, V-type sodium ATPase catalytic subunit A, V-type sodium ATPase subunit B | Authors: | Maruyama, S, Suzuki, K, Mizutani, K, Saito, Y, Imai, F.L, Ishizuka-Katsura, Y, Shirouzu, M, Ichiro, Y, Murata, T. | Deposit date: | 2018-02-27 | Release date: | 2019-02-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.384 Å) | Cite: | Metastable asymmetrical structure of a shaftless V1motor. Sci Adv, 5, 2019
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6IP6
| Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | Deposit date: | 2018-11-02 | Release date: | 2019-05-29 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | HCV IRES Captures an Actively Translating 80S Ribosome. Mol.Cell, 74, 2019
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2RU3
| Solution structure of c.elegans SUP-12 RRM in complex with RNA | Descriptor: | Protein SUP-12, isoform a, RNA (5'-R(*GP*UP*GP*UP*GP*C)-3') | Authors: | Takahashi, M, Kuwasako, K, Unzai, S, Tsuda, K, Yoshikawa, S, He, F, Kobayashi, N, Guntert, P, Shirouzu, M, Ito, T, Tanaka, A, Yokoyama, S, Hagiwara, M, Kuroyanagi, H, Muto, Y. | Deposit date: | 2013-11-12 | Release date: | 2014-08-13 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | RBFOX and SUP-12 sandwich a G base to cooperatively regulate tissue-specific splicing Nat.Struct.Mol.Biol., 21, 2014
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6IP5
| Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | Deposit date: | 2018-11-02 | Release date: | 2019-05-29 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | HCV IRES Captures an Actively Translating 80S Ribosome. Mol.Cell, 74, 2019
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2RPP
| Solution structure of Tandem zinc finger domain 12 in Muscleblind-like protein 2 | Descriptor: | Muscleblind-like protein 2, ZINC ION | Authors: | Abe, C, Dang, W, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2008-06-24 | Release date: | 2009-05-12 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the RNA binding domain in the human muscleblind-like protein 2 Protein Sci., 18, 2009
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6KRO
| Tankyrase-2 in complex with RK-582 | Descriptor: | 6-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-4-fluoranyl-1-methyl-1'-(8-methyl-4-oxidanylidene-3,5,6,7-tetrahydropyrido[2,3-d]pyrimidin-2-yl)spiro[indole-3,4'-piperidine]-2-one, GLYCEROL, PHOSPHATE ION, ... | Authors: | Niwa, H, Shirai, F, Sato, S, Tsumura, T, Okue, M, Shirouzu, M, Seimiya, H, Umehara, T. | Deposit date: | 2019-08-22 | Release date: | 2020-04-01 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer. J.Med.Chem., 63, 2020
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1VDY
| NMR Structure of the hypothetical ENTH-VHS domain At3g16270 from Arabidopsis thaliana | Descriptor: | hypothetical protein (RAFL09-17-B18) | Authors: | Lopez-Mendez, B, Pantoja-Uceda, D, Tomizawa, T, Koshiba, S, Kigawa, T, Shirouzu, M, Terada, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Seki, M, Shinozaki, K, Yokoyama, S, Guntert, P, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-03-25 | Release date: | 2005-05-03 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of the hypothetical ENTH-VHS domain AT3G16270 from arabidopsis thaliana To be Published
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7DQC
| Crystal structure of nucleotide-free mutant A(S23C)3B(N64C)3 complex from Enterococcus hirae V-ATPase | Descriptor: | GLYCEROL, V-type sodium ATPase catalytic subunit A, V-type sodium ATPase subunit B | Authors: | Maruyama, S, Suzuki, K, Mizutani, K, Imai, F.L, Ishizuka-Katsura, Y, Shirouzu, M, Murata, M. | Deposit date: | 2020-12-23 | Release date: | 2021-12-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.706 Å) | Cite: | The combination of high-speed AFM and X-ray crystallography reveals rotary catalytic mechanism of shaftless V1-ATPase To Be Published
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7CLX
| Crystal structure of the DOCK8 DHR-1 domain | Descriptor: | Dedicator of cytokinesis protein 8 | Authors: | Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S, Fukui, Y, Uruno, T. | Deposit date: | 2020-07-22 | Release date: | 2021-02-10 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A conserved PI(4,5)P2-binding domain is critical for immune regulatory function of DOCK8. Life Sci Alliance, 4, 2021
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7CLY
| Structure of the DOCK8 DHR-1 domain crystallized with di-C8-phosphatidylinositol-(4,5)-bisphosphate | Descriptor: | Dedicator of cytokinesis protein 8 | Authors: | Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S, Fukui, Y, Uruno, T. | Deposit date: | 2020-07-22 | Release date: | 2021-02-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.432 Å) | Cite: | A conserved PI(4,5)P2-binding domain is critical for immune regulatory function of DOCK8. Life Sci Alliance, 4, 2021
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7CD1
| Crystal structure of inhibitory Smad, Smad7 | Descriptor: | CHLORIDE ION, Mothers against decapentaplegic homolog 7, SULFATE ION | Authors: | Murayama, K, Kato-Murayama, M, Shirouzu, M. | Deposit date: | 2020-06-18 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structural basis for inhibitory effects of Smad7 on TGF-beta family signaling. J.Struct.Biol., 212, 2020
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7DEX
| Crystal Structures of Anthocyanin 5,3'-aromatic acyltransferase H174A mutant with caffeoyl-CoA | Descriptor: | Anthocyanin 5-aromatic acyltransferase, S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] (E)-3-[3,4-bis(oxidanyl)phenyl]prop-2-enethioate | Authors: | Murayama, K, Kato-Murayama, M, Shirouzu, M. | Deposit date: | 2020-11-05 | Release date: | 2021-09-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Anthocyanin 5,3'-aromatic acyltransferase from Gentiana triflora, a structural insight into biosynthesis of a blue anthocyanin. Phytochemistry, 186, 2021
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7DEV
| Crystal Structures of Anthocyanin 5,3'-aromatic acyltransferase from Gentiana triflora | Descriptor: | Anthocyanin 5-aromatic acyltransferase | Authors: | Murayama, K, Kato-Murayama, M, Shirouzu, M. | Deposit date: | 2020-11-05 | Release date: | 2021-09-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Anthocyanin 5,3'-aromatic acyltransferase from Gentiana triflora, a structural insight into biosynthesis of a blue anthocyanin. Phytochemistry, 186, 2021
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1VEE
| NMR structure of the hypothetical rhodanese domain At4g01050 from Arabidopsis thaliana | Descriptor: | proline-rich protein family | Authors: | Pantoja-Uceda, D, Lopez-Mendez, B, Koshiba, S, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Tanaka, A, Seki, M, Shinozaki, K, Yokoyama, S, Guntert, P, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-03-30 | Release date: | 2005-01-25 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of the rhodanese homology domain At4g01050(175-295) from Arabidopsis thaliana Protein Sci., 14, 2005
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2RUG
| Refined solution structure of the first RNA recognition motif domain in CPEB3 | Descriptor: | Cytoplasmic polyadenylation element-binding protein 3 | Authors: | Tsuda, K, Kuwasako, K, Nagata, T, Takahashi, M, Kigawa, T, Kobayashi, N, Guntert, P, Shirouzu, M, Yokoyama, S, Muto, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2014-04-15 | Release date: | 2014-09-17 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Novel RNA recognition motif domain in the cytoplasmic polyadenylation element binding protein 3. Proteins, 82, 2014
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2ROK
| Solution structure of the cap-binding domain of PARN complexed with the cap analog | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, poly(A)-specific ribonuclease | Authors: | Nagata, T, Suzuki, S, Endo, R, Shirouzu, M, Terada, T, Inoue, M, Kigawa, T, Guntert, P, Hayashizaki, Y, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2008-03-28 | Release date: | 2009-02-10 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The RRM domain of poly(A)-specific ribonuclease has a noncanonical binding site for mRNA cap analog recognition. Nucleic Acids Res., 36, 2008
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5B0U
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1WQU
| Solution structure of the human FES SH2 domain | Descriptor: | Proto-oncogene tyrosine-protein kinase FES/FPS | Authors: | Scott, A, Pantoja-Uceda, D, Koshiba, S, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Tanaka, A, Sugano, S, Yokoyama, S, Guntert, P, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-10-02 | Release date: | 2005-06-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the Src homology 2 domain from the human feline sarcoma oncogene Fes J.Biomol.NMR, 31, 2005
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7DQE
| Crystal structure of the ADP-bound mutant A(S23C)3B(N64C)3 complex from enterococcus hirae V-ATPase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SULFATE ION, ... | Authors: | Maruyama, S, Nakamoto, K, Suzuki, K, Mizutani, K, Imai, F.L, Ishizuka-Katsura, Y, Shirouzu, M, Murata, T. | Deposit date: | 2020-12-23 | Release date: | 2021-12-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.694 Å) | Cite: | The Combination of High-Speed AFM and X-ray Crystallography Reveals Rotary Catalytic Mechanism of Shaftless V1-ATPase To Be Published
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7DQD
| Crystal structure of the AMP-PNP-bound mutant A(S23C)3B(N64C)3 complex from enterococcus hirae V-ATPase | Descriptor: | GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Maruyama, S, Suzuki, K, Mizutani, K, Imai, F.L, Ishizuka-Katsura, Y, Shirouzu, M, Murata, T. | Deposit date: | 2020-12-23 | Release date: | 2021-12-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.383 Å) | Cite: | The combination of high-speed AFM and X-ray crystallography reveals rotary catalysis To Be Published
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7VP0
| Crystal structure of P domain from norovirus GI.9 capsid protein. | Descriptor: | MAGNESIUM ION, VP1 | Authors: | Katsura, K, Sakai, N, Hasegawa, K, Kimura-Someya, T, Shirouzu, M. | Deposit date: | 2021-10-15 | Release date: | 2022-08-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Lewis fucose is a key moiety for the recognition of histo-blood group antigens by GI.9 norovirus, as revealed by structural analysis. Febs Open Bio, 12, 2022
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7VA9
| Rba sphaeroides PufY-KO RC-LH1 dimer type-1 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN B, ... | Authors: | Bracun, L, Yamagata, A, Liu, L.N, Shirouzu, M. | Deposit date: | 2021-08-27 | Release date: | 2022-05-04 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Structural basis for the assembly and quinone transport mechanisms of the dimeric photosynthetic RC-LH1 supercomplex. Nat Commun, 13, 2022
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7VNM
| Rba sphaeroides PufY-KO RC-LH1 monomer | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, ... | Authors: | Bracun, L, Yamagata, A, Liu, L.N, Shirouzu, M. | Deposit date: | 2021-10-11 | Release date: | 2022-05-04 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Structural basis for the assembly and quinone transport mechanisms of the dimeric photosynthetic RC-LH1 supercomplex. Nat Commun, 13, 2022
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