6J4Z
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![BU of 6j4z by Molmil](/molmil-images/mine/6j4z) | RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome | 分子名称: | DNA (198-MER), DNA (42-MER), DNA-directed RNA polymerase subunit, ... | 著者 | Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S. | 登録日 | 2019-01-10 | 公開日 | 2019-02-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural insight into nucleosome transcription by RNA polymerase II with elongation factors. Science, 363, 2019
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6J51
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![BU of 6j51 by Molmil](/molmil-images/mine/6j51) | RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome, weak Elf1 (+1 position) | 分子名称: | DNA (198-MER), DNA (36-MER), DNA-directed RNA polymerase subunit, ... | 著者 | Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S. | 登録日 | 2019-01-10 | 公開日 | 2019-02-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural insight into nucleosome transcription by RNA polymerase II with elongation factors. Science, 363, 2019
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2Z10
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![BU of 2z10 by Molmil](/molmil-images/mine/2z10) | Crystal structure of putative acetyltransferase | 分子名称: | Ribosomal-protein-alanine acetyltransferase | 著者 | Murayama, K, Kato-Murayama, M, Terada, T, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-05-07 | 公開日 | 2007-11-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Genetic Encoding of 3-Iodo-l-Tyrosine in Escherichia coli for Single-Wavelength Anomalous Dispersion Phasing in Protein Crystallography Structure, 17, 2009
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6J4Y
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![BU of 6j4y by Molmil](/molmil-images/mine/6j4y) | RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-1) of the nucleosome (+1B) | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S. | 登録日 | 2019-01-10 | 公開日 | 2019-02-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural insight into nucleosome transcription by RNA polymerase II with elongation factors. Science, 363, 2019
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6JO0
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![BU of 6jo0 by Molmil](/molmil-images/mine/6jo0) | Crystal structure of the DTS-motif rhodopsin from Phaeocystis globosa virus 12T | 分子名称: | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DECANE, DODECANE, ... | 著者 | Hosaka, T, Kimura-Someya, T, Shirouzu, M. | 登録日 | 2019-03-19 | 公開日 | 2019-10-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.651 Å) | 主引用文献 | A distinct lineage of giant viruses brings a rhodopsin photosystem to unicellular marine predators. Proc.Natl.Acad.Sci.USA, 116, 2019
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5XOG
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![BU of 5xog by Molmil](/molmil-images/mine/5xog) | RNA Polymerase II elongation complex bound with Spt5 KOW5 and Elf1 | 分子名称: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (30-MER), DNA (39-MER), ... | 著者 | Ehara, H, Shirouzu, M, Sekine, S. | 登録日 | 2017-05-28 | 公開日 | 2017-08-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of the complete elongation complex of RNA polymerase II with basal factors Science, 357, 2017
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6JMR
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![BU of 6jmr by Molmil](/molmil-images/mine/6jmr) | CD98hc extracellular domain bound to HBJ127 Fab and MEM-108 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, ... | 著者 | Lee, Y, Nishizawa, T, Kusakizako, T, Oda, K, Ishitani, R, Yokoyama, T, Nakane, T, Shirouzu, M, Nureki, O. | 登録日 | 2019-03-13 | 公開日 | 2019-06-19 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc. Nat.Struct.Mol.Biol., 26, 2019
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5ZAB
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![BU of 5zab by Molmil](/molmil-images/mine/5zab) | Crystal structure of cf3-aequorin | 分子名称: | (2S)-8-benzyl-2-hydroperoxy-6-(4-hydroxyphenyl)-2-{[4-(trifluoromethyl)phenyl]methyl}imidazo[1,2-a]pyrazin-3(2H)-one, Aequorin-2 | 著者 | Inouye, S, Tomabechi, Y, Sekine, S.I, Shirouzu, M, Hosoya, T. | 登録日 | 2018-02-07 | 公開日 | 2018-06-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.147 Å) | 主引用文献 | Slow luminescence kinetics of semi-synthetic aequorin: expression, purification and structure determination of cf3-aequorin. J. Biochem., 164, 2018
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6JUX
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![BU of 6jux by Molmil](/molmil-images/mine/6jux) | Crystal structure of human ALK2 kinase domain with R206H mutation in complex with RK-71807 | 分子名称: | 4-(1-ethyl-3-pyridin-3-yl-pyrazol-4-yl)-~{N}-(4-piperazin-1-ylphenyl)pyrimidin-2-amine, Activin receptor type-1, SULFATE ION | 著者 | Sakai, N, Mishima-Tsumagari, C, Matsumoto, T, Shirouzu, M. | 登録日 | 2019-04-15 | 公開日 | 2020-04-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Basis of Activin Receptor-Like Kinase 2 (R206H) Inhibition by Bis-heteroaryl Pyrazole-Based Inhibitors for the Treatment of Fibrodysplasia Ossificans Progressiva Identified by the Integration of Ligand-Based and Structure-Based Drug Design Approaches. Acs Omega, 5, 2020
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7XN1
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![BU of 7xn1 by Molmil](/molmil-images/mine/7xn1) | Crystal structure of human acetylcholinesterase in complex with tacrine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Acetylcholinesterase, ... | 著者 | Dileep, K.V, Ihara, K, Mishima-Tsumagari, C, Kukimoto-Niino, M, Yonemochi, M, Hanada, K, Shirouzu, M, Zhang, K.Y.J. | 登録日 | 2022-04-27 | 公開日 | 2023-03-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Crystal structure of human acetylcholinesterase in complex with tacrine: Implications for drug discovery Int.J.Biol.Macromol., 210, 2022
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3AB3
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![BU of 3ab3 by Molmil](/molmil-images/mine/3ab3) | Crystal structure of p115RhoGEF RGS domain in complex with G alpha 13 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(k) subunit alpha, Guanine nucleotide-binding protein subunit alpha-13, ... | 著者 | Kukimoto-Niino, M, Mishima, C, Shirouzu, M, Kozasa, T, Yokoyama, S. | 登録日 | 2009-11-30 | 公開日 | 2010-12-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Identification of critical residues in G(alpha)13 for stimulation of p115RhoGEF activity and the structure of the G(alpha)13-p115RhoGEF regulator of G protein signaling homology (RH) domain complex. J.Biol.Chem., 286, 2011
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1WD5
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![BU of 1wd5 by Molmil](/molmil-images/mine/1wd5) | Crystal structure of TT1426 from Thermus thermophilus HB8 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, hypothetical protein TT1426 | 著者 | Shibata, R, Kukimoto-Niino, M, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2004-05-11 | 公開日 | 2004-11-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of a predicted phosphoribosyltransferase (TT1426) from Thermus thermophilus HB8 at 2.01 A resolution Protein Sci., 14, 2005
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7VGU
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![BU of 7vgu by Molmil](/molmil-images/mine/7vgu) | Time-resolved serial femtosecond crystallography structure of light-driven chloride ion-pumping rhodopsin, NM-R3 : structure obtained 1 msec after photoexcitation with bromide ion | 分子名称: | BROMIDE ION, Chloride pumping rhodopsin, DECANE, ... | 著者 | Hosaka, T, Nango, E, Nakane, T, Luo, F, Kimura-Someya, T, Shirouzu, M. | 登録日 | 2021-09-18 | 公開日 | 2022-02-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Conformational alterations in unidirectional ion transport of a light-driven chloride pump revealed using X-ray free electron lasers. Proc.Natl.Acad.Sci.USA, 119, 2022
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7VGT
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![BU of 7vgt by Molmil](/molmil-images/mine/7vgt) | Time-resolved serial femtosecond crystallography structure of light-driven chloride ion-pumping rhodopsin, NM-R3: resting state structure with bromide ion | 分子名称: | BROMIDE ION, Chloride pumping rhodopsin, DECANE, ... | 著者 | Hosaka, T, Nango, E, Nakane, T, Luo, F, Kimura-Someya, T, Shirouzu, M. | 登録日 | 2021-09-18 | 公開日 | 2022-02-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Conformational alterations in unidirectional ion transport of a light-driven chloride pump revealed using X-ray free electron lasers. Proc.Natl.Acad.Sci.USA, 119, 2022
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7VGV
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![BU of 7vgv by Molmil](/molmil-images/mine/7vgv) | Anion free form of light-driven chloride ion-pumping rhodopsin, NM-R3, structure determined by serial femtosecond crystallography at SACLA | 分子名称: | CHLORIDE ION, Chloride pumping rhodopsin, HEXADECANE, ... | 著者 | Hosaka, T, Nango, E, Nakane, T, Luo, F, Kimura-Someya, T, Shirouzu, M. | 登録日 | 2021-09-18 | 公開日 | 2022-02-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Conformational alterations in unidirectional ion transport of a light-driven chloride pump revealed using X-ray free electron lasers. Proc.Natl.Acad.Sci.USA, 119, 2022
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1X4S
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![BU of 1x4s by Molmil](/molmil-images/mine/1x4s) | Solution structure of zinc finger HIT domain in protein FON | 分子名称: | ZINC ION, Zinc finger HIT domain containing protein 2 | 著者 | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-05-14 | 公開日 | 2005-11-14 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the zinc finger HIT domain in protein FON Protein Sci., 16, 2007
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1WV8
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![BU of 1wv8 by Molmil](/molmil-images/mine/1wv8) | Crystal structure of hypothetical protein TTHA1013 from an extremely thermophilic bacterium thermus thermophilus HB8 | 分子名称: | hypothetical protein TTHA1013 | 著者 | Mizohata, E, Hattori, M, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2004-12-12 | 公開日 | 2005-06-12 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of the hypothetical protein TTHA1013 from Thermus thermophilus HB8 Proteins, 61, 2005
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1X42
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![BU of 1x42 by Molmil](/molmil-images/mine/1x42) | Crystal structure of a haloacid dehalogenase family protein (PH0459) from Pyrococcus horikoshii OT3 | 分子名称: | hypothetical protein PH0459 | 著者 | Arai, R, Kukimoto-Niino, M, Sugahara, M, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-05-12 | 公開日 | 2005-11-12 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the probable haloacid dehalogenase PH0459 from Pyrococcus horikoshii OT3 Protein Sci., 15, 2006
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3AQF
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![BU of 3aqf by Molmil](/molmil-images/mine/3aqf) | Crystal structure of the human CRLR/RAMP2 extracellular complex | 分子名称: | Calcitonin gene-related peptide type 1 receptor, Receptor activity-modifying protein 2 | 著者 | Kusano, S, Kukimono-Niino, M, Shirouzu, M, Shindo, T, Yokoyama, S. | 登録日 | 2010-10-29 | 公開日 | 2011-11-02 | 最終更新日 | 2012-07-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding Protein Sci., 21, 2012
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2YQP
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![BU of 2yqp by Molmil](/molmil-images/mine/2yqp) | Solution structure of the zf-HIT domain in DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 | 分子名称: | Probable ATP-dependent RNA helicase DDX59, ZINC ION | 著者 | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-30 | 公開日 | 2007-10-02 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the zf-HIT domain in DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 To be Published
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2Z0O
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![BU of 2z0o by Molmil](/molmil-images/mine/2z0o) | Crystal structure of APPL1-BAR-PH domain | 分子名称: | DCC-interacting protein 13-alpha | 著者 | Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-05-07 | 公開日 | 2008-05-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Crystal structure of APPL1-BAR-PH domain To be Published
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2YU4
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![BU of 2yu4 by Molmil](/molmil-images/mine/2yu4) | Solution structure of the SP-RING domain in non-SMC element 2 homolog (MMS21, S. cerevisiae) | 分子名称: | E3 SUMO-protein ligase NSE2, ZINC ION | 著者 | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-05 | 公開日 | 2007-10-09 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the SP-RING domain in non-SMC element 2 homolog (MMS21, S. cerevisiae) To be Published
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2YWH
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![BU of 2ywh by Molmil](/molmil-images/mine/2ywh) | Crystal structure of GDP-bound LepA from Aquifex aeolicus | 分子名称: | GTP-binding protein LepA, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Kawazoe, M, Takemoto, C, Kaminishi, T, Nishino, A, Nakayama-Ushikoshi, R, Hanawa-Suetsugu, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-20 | 公開日 | 2008-04-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Crystal structures of GTP-binding protein LepA from Aquifex aeolicus. To be Published
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2Z0V
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![BU of 2z0v by Molmil](/molmil-images/mine/2z0v) | Crystal structure of BAR domain of Endophilin-III | 分子名称: | SH3-containing GRB2-like protein 3 | 著者 | Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-05-07 | 公開日 | 2008-05-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Crystal structure of BAR domain of Endophilin-III To be Published
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2YSV
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![BU of 2ysv by Molmil](/molmil-images/mine/2ysv) | Solution structure of C2H2 type Zinc finger domain 17 in Zinc finger protein 473 | 分子名称: | ZINC ION, Zinc finger protein 473 | 著者 | Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-04 | 公開日 | 2007-10-09 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of C2H2 type Zinc finger domain 17 in Zinc finger protein 473 To be Published
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