2P6M
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![BU of 2p6m by Molmil](/molmil-images/mine/2p6m) | Crystal structure of TTHB049 from Thermus thermophilus HB8 | Descriptor: | Alpha-ribazole-5'-phosphate phosphatase, GLYCEROL, SODIUM ION | Authors: | Sugahara, M, Matsuura, Y, Morikawa, Y, Shimada, H, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-19 | Release date: | 2007-09-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of TTHB049 from Thermus thermophilus HB8 To be Published
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4TKC
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![BU of 4tkc by Molmil](/molmil-images/mine/4tkc) | Japanese Marasmius oreades lectin complexed with mannose | Descriptor: | GLYCEROL, Mannose recognizing lectin, alpha-D-mannopyranose, ... | Authors: | Noma, Y, Shimokawa, M, Maeganeku, C, Motoshima, H, Watanabe, K, Minami, Y, Yagi, F. | Deposit date: | 2014-05-26 | Release date: | 2015-06-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | Structure of Japanese Marasmius oreades lectin complexed with mannose. To Be Published
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6AEK
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![BU of 6aek by Molmil](/molmil-images/mine/6aek) | Crystal structure of ENPP1 in complex with pApG | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, ... | Authors: | Kato, K, Nishimasu, H, Hirano, S, Hirano, H, Ishitani, R, Nureki, O. | Deposit date: | 2018-08-05 | Release date: | 2019-03-06 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1. Nat Commun, 9, 2018
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4XZG
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![BU of 4xzg by Molmil](/molmil-images/mine/4xzg) | Crystal structure of HIRAN domain of human HLTF | Descriptor: | Helicase-like transcription factor | Authors: | Ikegaya, Y, Hara, K, Hashimoto, H. | Deposit date: | 2015-02-04 | Release date: | 2015-04-15 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of a Novel DNA-binding Domain of Helicase-like Transcription Factor (HLTF) and Its Functional Implication in DNA Damage Tolerance J.Biol.Chem., 290, 2015
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6AEL
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![BU of 6ael by Molmil](/molmil-images/mine/6ael) | Crystal structure of ENPP1 in complex with 3'3'-cGAMP | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, ... | Authors: | Kato, K, Nishimasu, H, Hirano, S, Hirano, H, Ishitani, R, Nureki, O. | Deposit date: | 2018-08-05 | Release date: | 2019-03-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1. Nat Commun, 9, 2018
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4YBG
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![BU of 4ybg by Molmil](/molmil-images/mine/4ybg) | Crystal structure of the MAEL domain of Drosophila melanogaster Maelstrom | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Protein maelstrom, ... | Authors: | Matsumoto, N, Ishitani, R, Nishimasu, H, Nureki, O. | Deposit date: | 2015-02-18 | Release date: | 2015-04-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.602 Å) | Cite: | Crystal Structure and Activity of the Endoribonuclease Domain of the piRNA Pathway Factor Maelstrom Cell Rep, 11, 2015
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4L3O
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![BU of 4l3o by Molmil](/molmil-images/mine/4l3o) | Crystal Structure of SIRT2 in complex with the macrocyclic peptide S2iL5 | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, NAD-dependent protein deacetylase sirtuin-2, ... | Authors: | Yamagata, K, Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2013-06-06 | Release date: | 2014-02-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.518 Å) | Cite: | Structural Basis for Potent Inhibition of SIRT2 Deacetylase by a Macrocyclic Peptide Inducing Dynamic Structural Change Structure, 22, 2013
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6LMU
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![BU of 6lmu by Molmil](/molmil-images/mine/6lmu) | Cryo-EM structure of the human CALHM2 | Descriptor: | Calcium homeostasis modulator protein 2 | Authors: | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-12-26 | Release date: | 2020-07-29 | Last modified: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Sci Adv, 6, 2020
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6LMX
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![BU of 6lmx by Molmil](/molmil-images/mine/6lmx) | Cryo-EM structure of the CALHM chimeric construct (9-mer) | Descriptor: | Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2 | Authors: | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-12-26 | Release date: | 2020-07-29 | Last modified: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Sci Adv, 6, 2020
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6LMV
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![BU of 6lmv by Molmil](/molmil-images/mine/6lmv) | Cryo-EM structure of the C. elegans CLHM-1 | Descriptor: | Calcium homeostasis modulator protein | Authors: | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-12-26 | Release date: | 2020-07-29 | Last modified: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Sci Adv, 6, 2020
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6LMW
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![BU of 6lmw by Molmil](/molmil-images/mine/6lmw) | Cryo-EM structure of the CALHM chimeric construct (8-mer) | Descriptor: | Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2 | Authors: | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-12-26 | Release date: | 2020-07-29 | Last modified: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Sci Adv, 6, 2020
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1WD8
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![BU of 1wd8 by Molmil](/molmil-images/mine/1wd8) | Calcium free form of human peptidylarginine deiminase type4 (PAD4) | Descriptor: | Protein-arginine deiminase type IV | Authors: | Arita, K, Hashimoto, H, Shimizu, T, Nakashima, K, Yamada, M, Sato, M. | Deposit date: | 2004-05-12 | Release date: | 2004-07-13 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for Ca(2+)-induced activation of human PAD4 Nat.Struct.Mol.Biol., 11, 2004
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2RU7
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![BU of 2ru7 by Molmil](/molmil-images/mine/2ru7) | Refined structure of RNA aptamer in complex with the partial binding peptide of prion protein | Descriptor: | P16 peptide from Major prion protein, RNA_(5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3') | Authors: | Hayashi, T, Oshima, H, Mashima, T, Nagata, T, Katahira, M, Kinoshita, M. | Deposit date: | 2013-12-24 | Release date: | 2014-05-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Binding of an RNA aptamer and a partial peptide of a prion protein: crucial importance of water entropy in molecular recognition. Nucleic Acids Res., 42, 2014
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7W86
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![BU of 7w86 by Molmil](/molmil-images/mine/7w86) | Crystal structure of the DYW domain of DYW1 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ... | Authors: | Sawada, Y, Shimizu, H, Toma-Fukai, S, Shimizu, T. | Deposit date: | 2021-12-07 | Release date: | 2022-12-14 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insight into the activation of an Arabidopsis organellar C-to-U RNA editing enzyme by active site complementation. Plant Cell, 35, 2023
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1NI6
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![BU of 1ni6 by Molmil](/molmil-images/mine/1ni6) | Comparisions of the Heme-Free and-Bound Crystal Structures of Human Heme Oxygenase-1 | Descriptor: | CHLORIDE ION, Heme oxygenase 1, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | Authors: | Lad, L, Schuller, D.J, Friedman, J, Li, H, Shimizu, H, Ortiz de Montellano, P.R, Poulos, T.L. | Deposit date: | 2002-12-21 | Release date: | 2003-04-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Comparison of the heme-free and -bound crystal structures of human heme oxygenase-1 J.Biol.Chem., 278, 2003
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8FJN
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![BU of 8fjn by Molmil](/molmil-images/mine/8fjn) | Crystal Structure of the Trypanosoma brucei DOT1A histone H3K76 methyltransferase in complex with AdoHcy - C2221 space group | Descriptor: | CALCIUM ION, CHLORIDE ION, Histone-lysine N-methyltransferase, ... | Authors: | Frisbie, V.S, Hashimoto, H, Debler, E.W. | Deposit date: | 2022-12-20 | Release date: | 2024-02-07 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Two DOT1 enzymes cooperatively mediate efficient ubiquitin-independent histone H3 lysine 76 tri-methylation in kinetoplastids. Nat Commun, 15, 2024
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1GEB
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![BU of 1geb by Molmil](/molmil-images/mine/1geb) | X-RAY CRYSTAL STRUCTURE AND CATALYTIC PROPERTIES OF THR252ILE MUTANT OF CYTOCHROME P450CAM | Descriptor: | CAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Hishiki, T, Shimada, H, Nagano, S, Park, S.-Y, Ishimura, Y. | Deposit date: | 2000-11-01 | Release date: | 2000-11-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | X-ray crystal structure and catalytic properties of Thr252Ile mutant of cytochrome P450cam: roles of Thr252 and water in the active center. J.Biochem., 128, 2000
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5HRT
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![BU of 5hrt by Molmil](/molmil-images/mine/5hrt) | Crystal structure of mouse autotaxin in complex with a DNA aptamer | Descriptor: | CALCIUM ION, CHLORIDE ION, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, ... | Authors: | Kato, K, Nishimasu, H, Morita, J, Ishitani, R, Nureki, O. | Deposit date: | 2016-01-24 | Release date: | 2016-04-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | Structural basis for specific inhibition of Autotaxin by a DNA aptamer Nat.Struct.Mol.Biol., 23, 2016
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1PKF
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![BU of 1pkf by Molmil](/molmil-images/mine/1pkf) | Crystal Structure of Epothilone D-bound Cytochrome P450epoK | Descriptor: | EPOTHILONE D, PROTOPORPHYRIN IX CONTAINING FE, cytochrome p450EpoK | Authors: | Nagano, S, Li, H, Shimizu, H, Nishida, C, Ogura, H, Ortiz de Montellano, P.R, Poulos, T.L. | Deposit date: | 2003-06-05 | Release date: | 2003-10-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Epothilone D-bound, Epothilone B-bound, and Substrate-free Forms of Cytochrome P450epoK J.Biol.Chem., 278, 2003
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5F8B
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![BU of 5f8b by Molmil](/molmil-images/mine/5f8b) | Crystallographic Structure of PsoE with Co | Descriptor: | (5~{S},8~{S},9~{R})-2-[(~{E})-hex-1-enyl]-8-methoxy-3-methyl-9-oxidanyl-8-(phenylcarbonyl)-1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione, COBALT (II) ION, GLUTATHIONE, ... | Authors: | Hara, K, Hashimoto, H, Yamamoto, T, Tsunematsu, Y, Watanabe, K. | Deposit date: | 2015-12-09 | Release date: | 2016-04-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Oxidative trans to cis Isomerization of Olefins in Polyketide Biosynthesis. Angew. Chem. Int. Ed. Engl., 55, 2016
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1Q5D
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![BU of 1q5d by Molmil](/molmil-images/mine/1q5d) | Epothilone B-bound Cytochrome P450epoK | Descriptor: | 7,11-DIHYDROXY-8,8,10,12,16-PENTAMETHYL-3-[1-METHYL-2-(2-METHYL-THIAZOL-4-YL)VINYL]-4,17-DIOXABICYCLO[14.1.0]HEPTADECANE-5,9-DIONE, P450 epoxidase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Nagano, S, Li, H, Shimizu, H, Nishida, C, Ogura, H, Ortiz de Montellano, P.R, Poulos, T.L. | Deposit date: | 2003-08-06 | Release date: | 2003-10-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Crystal structures of epothilone D-bound, epothilone B-bound, and substrate-free forms of cytochrome P450epoK J.Biol.Chem., 278, 2003
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1Q5E
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![BU of 1q5e by Molmil](/molmil-images/mine/1q5e) | Substrate-free Cytochrome P450epoK | Descriptor: | P450 epoxidase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Nagano, S, Li, H, Shimizu, H, Nishida, C, Ogura, H, Ortiz de Montellano, P.R, Poulos, T.L. | Deposit date: | 2003-08-06 | Release date: | 2003-10-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Crystal structures of epothilone D-bound, epothilone B-bound, and substrate-free forms of cytochrome P450epoK J.Biol.Chem., 278, 2003
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1OM4
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![BU of 1om4 by Molmil](/molmil-images/mine/1om4) | STRUCTURE OF RAT NEURONAL NOS HEME DOMAIN WITH L-ARGININE BOUND | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ARGININE, ... | Authors: | Li, H, Martasek, P, Shimizu, H, Masters, B.S.S, Poulos, T.L, Raman, C.S. | Deposit date: | 2003-02-24 | Release date: | 2003-03-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of Rat Neuronal NOS Heme Domain with L-Arginine Bound To be Published
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5FHI
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![BU of 5fhi by Molmil](/molmil-images/mine/5fhi) | Crystallographic structure of PsoE without Co | Descriptor: | GLUTATHIONE, Glutathione S-transferase, putative | Authors: | Hara, K, Hashimoto, H, Yamamoto, T, Tsunematsu, Y, Watanabe, K. | Deposit date: | 2015-12-22 | Release date: | 2016-04-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Oxidative trans to cis Isomerization of Olefins in Polyketide Biosynthesis. Angew. Chem. Int. Ed. Engl., 55, 2016
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5B13
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![BU of 5b13 by Molmil](/molmil-images/mine/5b13) | Crystal structure of phycoerythrin | Descriptor: | PHYCOCYANOBILIN, PHYCOUROBILIN, Phycoerythrin alpha subunit, ... | Authors: | Tanaka, Y, Gai, Z, Kishimura, H. | Deposit date: | 2015-11-18 | Release date: | 2016-10-05 | Last modified: | 2020-02-26 | Method: | X-RAY DIFFRACTION (2.094 Å) | Cite: | Structural properties of phycoerythrin from dulse palmaria palmata J FOOD BIOCHEM., 2016
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