8XGR
 
 | | ETB-eGt complex bound to endothelin-1 | | 分子名称: | Camelid antibody VHH fragment, Endothelin receptor type B, Endothelin-1, ... | | 著者 | Oshima, H.S, Sano, F.K, Akasaka, H, Iwama, A, Shihoya, W, Nureki, O. | | 登録日 | 2023-12-15 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Optimizing cryo-EM structural analysis of G i -coupling receptors via engineered G t and Nb35 application.
Biochem.Biophys.Res.Commun., 693, 2024
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7C86
 | | Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin: Dark state structure | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RETINAL, ... | | 著者 | Oda, K, Nomura, T, Nakane, T, Yamashita, K, Inoue, K, Ito, S, Vierock, J, Hirata, K, Maturana, A.D, Katayama, K, Ikuta, T, Ishigami, I, Izume, T, Umeda, R, Eguma, R, Oishi, S, Kasuya, G, Kato, T, Kusakizako, T, Shihoya, W, Shimada, H, Takatsuji, T, Takemoto, M, Taniguchi, R, Tomita, A, Nakamura, R, Fukuda, M, Miyauchi, H, Lee, Y, Nango, E, Tanaka, R, Tanaka, T, Sugahara, M, Kimura, T, Shimamura, T, Fujiwara, T, Yamanaka, Y, Owada, S, Joti, Y, Tono, K, Ishitani, R, Hayashi, S, Kandori, H, Hegemann, P, Iwata, S, Kubo, M, Nishizawa, T, Nureki, O. | | 登録日 | 2020-05-28 | | 公開日 | 2021-04-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin.
Elife, 10, 2021
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8YEL
 | | Cryo-EM structure of the channelrhodopsin GtCCR4 | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cation channel rhodopsin 4, RETINAL | | 著者 | Tanaka, T, Iida, W, Sano, F.K, Oda, K, Shihoya, W, Nureki, O. | | 登録日 | 2024-02-22 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | | 主引用文献 | The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4.
Mol.Cell, 84, 2024
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8YEJ
 | | Cryo-EM structure of the channelrhodopsin GtCCR2 focused on the monomer | | 分子名称: | GtCCR2, RETINAL | | 著者 | Tanaka, T, Iida, W, Sano, F.K, Oda, K, Shihoya, W, Nureki, O. | | 登録日 | 2024-02-22 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | | 主引用文献 | The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4.
Mol.Cell, 84, 2024
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8YEK
 | | Cryo-EM structure of the channelrhodopsin GtCCR2 | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GtCCR2, RETINAL | | 著者 | Tanaka, T, Iida, W, Sano, F.K, Oda, K, Shihoya, W, Nureki, O. | | 登録日 | 2024-02-22 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | | 主引用文献 | The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4.
Mol.Cell, 84, 2024
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1J1N
 | | Structure Analysis of AlgQ2, A Macromolecule(Alginate)-Binding Periplasmic Protein Of Sphingomonas Sp. A1., Complexed with an Alginate Tetrasaccharide | | 分子名称: | AlgQ2, CALCIUM ION, beta-D-mannopyranuronic acid-(1-4)-alpha-D-mannopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-D-mannopyranuronic acid | | 著者 | Momma, K, Mikami, B, Mishima, Y, Hashimoto, W, Murata, K. | | 登録日 | 2002-12-11 | | 公開日 | 2003-06-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of AlgQ2, a macromolecule (alginate)-binding protein of Sphingomonas sp. A1, complexed with an alginate tetrasaccharide at 1.6-A resolution
J.BIOL.CHEM., 278, 2003
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8I2Z
 | | Cryo-EM structure of the zeaxanthin-bound kin4B8 | | 分子名称: | RETINAL, Xanthorhodopsin, Zeaxanthin | | 著者 | Murakoshi, S, Chazan, A, Shihoya, W, Beja, O, Nureki, O. | | 登録日 | 2023-01-15 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (2 Å) | | 主引用文献 | Phototrophy by antenna-containing rhodopsin pumps in aquatic environments.
Nature, 615, 2023
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1QXH
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7DB6
 | | human melatonin receptor MT1 - Gi1 complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Okamoto, H.H, Kusakizako, T, Shihioya, W, Yamashita, K, Nishizawa, T, Nureki, O. | | 登録日 | 2020-10-19 | | 公開日 | 2021-08-18 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structure of the human MT 1 -G i signaling complex.
Nat.Struct.Mol.Biol., 28, 2021
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2RGK
 | | Functional annotation of Escherichia coli yihS-encoded protein | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Uncharacterized sugar isomerase yihS | | 著者 | Itoh, T, Mikami, B, Hashimoto, W, Murata, K. | | 登録日 | 2007-10-03 | | 公開日 | 2008-08-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of YihS in complex with D-mannose: structural annotation of Escherichia coli and Salmonella enterica yihS-encoded proteins to an aldose-ketose isomerase
J.Mol.Biol., 377, 2008
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7D3S
 | | Human SECR in complex with an engineered Gs heterotrimer | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Fukuhara, S, Kobayashi, K, Kusakizako, T, Shihoya, W, Nureki, O. | | 登録日 | 2020-09-20 | | 公開日 | 2020-11-04 | | 最終更新日 | 2020-12-30 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure of the human secretin receptor coupled to an engineered heterotrimeric G protein.
Biochem.Biophys.Res.Commun., 533, 2020
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1KWH
 | | Structure Analysis AlgQ2, a Macromolecule(alginate)-Binding Periplasmic Protein of Sphingomonas sp. A1. | | 分子名称: | CALCIUM ION, Macromolecule-Binding Periplasmic Protein | | 著者 | Momma, K, Mikami, B, Mishima, Y, Hashimoto, W, Murata, K. | | 登録日 | 2002-01-29 | | 公開日 | 2002-02-13 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of AlgQ2, a macromolecule (alginate)-binding protein of Sphingomonas sp. A1 at 2.0A resolution.
J.Mol.Biol., 316, 2002
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2A0X
 | | Structure of human purine nucleoside phosphorylase H257F mutant | | 分子名称: | 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, Purine nucleoside phosphorylase, SULFATE ION | | 著者 | Murkin, A.S, Shi, W, Schramm, V.L. | | 登録日 | 2005-06-17 | | 公開日 | 2006-06-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Neighboring group participation in the transition state of human purine nucleoside phosphorylase.
Biochemistry, 46, 2007
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2GH4
 | | YteR/D143N/dGalA-Rha | | 分子名称: | 2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid-(1-2)-alpha-L-rhamnopyranose, Putative glycosyl hydrolase yteR | | 著者 | Itoh, T, Ochiai, A, Mikami, B, Hashimoto, W, Murata, K. | | 登録日 | 2006-03-25 | | 公開日 | 2006-08-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of unsaturated rhamnogalacturonyl hydrolase complexed with substrate
Biochem.Biophys.Res.Commun., 347, 2006
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6A6U
 | | Crystal structure of the modified fructosyl peptide oxidase from Aspergillus nidulans with R61G mutation, in complex with FSA | | 分子名称: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, 1-S-(carboxymethyl)-1-thio-beta-D-fructopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Ogawa, N, Maruyama, Y, Itoh, T, Hashimoto, W, Murata, K. | | 登録日 | 2018-06-29 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.945 Å) | | 主引用文献 | Creation of haemoglobin A1c direct oxidase from fructosyl peptide oxidase by combined structure-based site specific mutagenesis and random mutagenesis.
Sci Rep, 9, 2019
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6A6T
 | | Crystal structure of the modified fructosyl peptide oxidase from Aspergillus nidulans with R61G mutation | | 分子名称: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, FLAVIN-ADENINE DINUCLEOTIDE, Fructosyl amine: oxygen oxidoreductase, ... | | 著者 | Ogawa, N, Maruyama, Y, Itoh, T, Hashimoto, W, Murata, K. | | 登録日 | 2018-06-29 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | Creation of haemoglobin A1c direct oxidase from fructosyl peptide oxidase by combined structure-based site specific mutagenesis and random mutagenesis.
Sci Rep, 9, 2019
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6A6V
 | | Crystal structure of the modified fructosyl peptide oxidase from Aspergillus nidulans with 7 additional mutations, in complex with FSA | | 分子名称: | 1-S-(carboxymethyl)-1-thio-beta-D-fructopyranose, FLAVIN-ADENINE DINUCLEOTIDE, Fructosyl amine: oxygen oxidoreductase | | 著者 | Ogawa, N, Maruyama, Y, Itoh, T, Hashimoto, W, Murata, K. | | 登録日 | 2018-06-29 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Creation of haemoglobin A1c direct oxidase from fructosyl peptide oxidase by combined structure-based site specific mutagenesis and random mutagenesis.
Sci Rep, 9, 2019
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6A6R
 | | Crystal structure of the modified fructosyl peptide oxidase from Aspergillus nidulans, Seleno-methionine Derivative | | 分子名称: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, FLAVIN-ADENINE DINUCLEOTIDE, Fructosyl amine: oxygen oxidoreductase, ... | | 著者 | Ogawa, N, Maruyama, Y, Itoh, T, Hashimoto, W, Murata, K. | | 登録日 | 2018-06-29 | | 公開日 | 2019-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.609 Å) | | 主引用文献 | Creation of haemoglobin A1c direct oxidase from fructosyl peptide oxidase by combined structure-based site specific mutagenesis and random mutagenesis.
Sci Rep, 9, 2019
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6LRY
 | | Crystal structure of human endothelin ETB receptor in complex with sarafotoxin S6b | | 分子名称: | Endothelin receptor type B,Endolysin,Endothelin receptor type B, Sarafotoxin-B | | 著者 | Izume, T, Miyauchi, H, Shihoya, W, Nureki, O. | | 登録日 | 2020-01-16 | | 公開日 | 2020-02-12 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of human endothelin ETBreceptor in complex with sarafotoxin S6b.
Biochem.Biophys.Res.Commun., 528, 2020
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4F13
 | | Alginate lyase A1-III Y246F complexed with tetrasaccharide | | 分子名称: | 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid, Alginate lyase, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid | | 著者 | Mikami, B, Ban, M, Suzuki, S, Yoon, H.-J, Miyake, O, Yamasaki, M, Ogura, K, Maruyama, Y, Hashimoto, W, Murata, K. | | 登録日 | 2012-05-06 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.208 Å) | | 主引用文献 | Induced-fit motion of a lid loop involved in catalysis in alginate lyase A1-III
Acta Crystallogr.,Sect.D, 68, 2012
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5GX7
 | | Crystal structure of solute-binding protein complexed with unsaturated chondroitin disaccharide with a sulfate group at C-6 position of GalNAc | | 分子名称: | 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-6-O-sulfo-beta-D-galactopyranose, CALCIUM ION, Extracellular solute-binding protein family 1 | | 著者 | Oiki, S, Mikami, B, Murata, K, Hashimoto, W. | | 登録日 | 2016-09-15 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.991 Å) | | 主引用文献 | A bacterial ABC transporter enables import of mammalian host glycosaminoglycans
Sci Rep, 7, 2017
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5GUB
 | | Crystal structure of solute-binding protein complexed with sulfate group-free unsaturated chondroitin disaccharide | | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ... | | 著者 | Oiki, S, Mikami, B, Murata, K, Hashimoto, W. | | 登録日 | 2016-08-26 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | A bacterial ABC transporter enables import of mammalian host glycosaminoglycans
Sci Rep, 7, 2017
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4F10
 | | Alginate lyase A1-III H192A complexed with tetrasaccharide | | 分子名称: | 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid, Alginate lyase, alpha-L-gulopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid | | 著者 | Mikami, B, Ban, M, Suzuki, S, Yoon, H.-J, Miyake, O, Yamasaki, M, Ogura, K, Maruyama, Y, Hashimoto, W, Murata, K. | | 登録日 | 2012-05-05 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Induced-fit motion of a lid loop involved in catalysis in alginate lyase A1-III
Acta Crystallogr.,Sect.D, 68, 2012
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5GX8
 | | Crystal structure of solute-binding protein related to glycosaminoglycans | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, D(-)-TARTARIC ACID, ... | | 著者 | Oiki, S, Mikami, B, Murata, K, Hashimoto, W. | | 登録日 | 2016-09-15 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.778 Å) | | 主引用文献 | A bacterial ABC transporter enables import of mammalian host glycosaminoglycans
Sci Rep, 7, 2017
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5GX6
 | | Crystal structure of solute-binding protein complexed with unsaturated chondroitin disaccharide with a sulfate group at C-4 position of GalNAc | | 分子名称: | 1,2-ETHANEDIOL, 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, CALCIUM ION, ... | | 著者 | Oiki, S, Mikami, B, Murata, K, Hashimoto, W. | | 登録日 | 2016-09-15 | | 公開日 | 2017-07-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | A bacterial ABC transporter enables import of mammalian host glycosaminoglycans
Sci Rep, 7, 2017
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