3UG2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ug2 by Molmil](/molmil-images/mine/3ug2) | Crystal structure of the mutated EGFR kinase domain (G719S/T790M) in complex with gefitinib | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor, Gefitinib | Authors: | Parker, L.J, Handa, N, Yoshikawa, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. | Deposit date: | 2011-11-02 | Release date: | 2012-03-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor Oncogene, 32, 2013
|
|
2CW9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cw9 by Molmil](/molmil-images/mine/2cw9) | Crystal structure of human Tim44 C-terminal domain | Descriptor: | PENTAETHYLENE GLYCOL, translocase of inner mitochondrial membrane | Authors: | Handa, N, Kishishita, S, Morita, S, Kinoshita, Y, Nagano, Y, Uda, H, Terada, T, Uchikubo, T, Takemoto, C, Jin, Z, Chrzas, J, Chen, L, Liu, Z.-J, Wang, B.-C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-06-17 | Release date: | 2005-12-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the human Tim44 C-terminal domain in complex with pentaethylene glycol: ligand-bound form. Acta Crystallogr.,Sect.D, 63, 2007
|
|
2ZBX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zbx by Molmil](/molmil-images/mine/2zbx) | Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (wild type) with imidazole bound | Descriptor: | Cytochrome P450-SU1, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sugimoto, H, Shinkyo, R, Hayashi, K, Yoneda, S, Yamada, M, Kamakura, M, Ikushiro, S, Shiro, Y, Sakaki, T. | Deposit date: | 2007-10-30 | Release date: | 2008-04-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1alpha,25-Dihydroxyvitamin D3 Biochemistry, 47, 2008
|
|
2ZBZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zbz by Molmil](/molmil-images/mine/2zbz) | Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (R84A mutant) in complex with 1,25-dihydroxyvitamin D3 | Descriptor: | 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sugimoto, H, Shinkyo, R, Hayashi, K, Yoneda, S, Yamada, M, Kamakura, M, Ikushiro, S, Shiro, Y, Sakaki, T. | Deposit date: | 2007-10-30 | Release date: | 2008-04-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1alpha,25-Dihydroxyvitamin D3 Biochemistry, 47, 2008
|
|
3UG1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ug1 by Molmil](/molmil-images/mine/3ug1) | Crystal structure of the mutated EGFR kinase domain (G719S/T790M) in the apo form | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor | Authors: | Parker, L.J, Handa, N, Yoshikawa, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. | Deposit date: | 2011-11-02 | Release date: | 2012-03-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor Oncogene, 32, 2013
|
|
2MGZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mgz by Molmil](/molmil-images/mine/2mgz) | Solution structure of RBFOX family ASD-1 RRM and SUP-12 RRM in ternary complex with RNA | Descriptor: | Protein ASD-1, isoform a, Protein SUP-12, ... | Authors: | Takahashi, M, Kuwasako, K, Unzai, S, Tsuda, K, Yoshikawa, S, He, F, Kobayashi, N, Guntert, P, Shirouzu, M, Ito, T, Tanaka, A, Yokoyama, S, Hagiwara, M, Kuroyanagi, H, Muto, Y. | Deposit date: | 2013-11-12 | Release date: | 2014-08-13 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | RBFOX and SUP-12 sandwich a G base to cooperatively regulate tissue-specific splicing Nat.Struct.Mol.Biol., 21, 2014
|
|
6KQT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6kqt by Molmil](/molmil-images/mine/6kqt) | Crystal Structure of GH136 lacto-N-biosidase from Eubacterium ramulus - native protein | Descriptor: | SODIUM ION, TRIETHYLENE GLYCOL, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yamada, C, Arakawa, T, Pichler, M.J, Abou Hachem, M, Fushinobu, S. | Deposit date: | 2019-08-18 | Release date: | 2020-06-10 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways. Nat Commun, 11, 2020
|
|
6KQS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6kqs by Molmil](/molmil-images/mine/6kqs) | Crystal Structure of GH136 lacto-N-biosidase from Eubacterium ramulus - selenomethionine derivative | Descriptor: | GLYCEROL, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, lacto-N-biosidase | Authors: | Yamada, C, Arakawa, T, Pichler, M.J, Abou Hachem, M, Fushinobu, S. | Deposit date: | 2019-08-18 | Release date: | 2020-06-10 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways. Nat Commun, 11, 2020
|
|
3AXG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3axg by Molmil](/molmil-images/mine/3axg) | Structure of 6-aminohexanoate-oligomer hydrolase | Descriptor: | Endotype 6-aminohexanoat-oligomer hydrolase, SODIUM ION | Authors: | Negoro, S, Shibata, N, Tanaka, Y, Yasuhira, K, Shibata, H, Hashimoto, H, Lee, Y.H, Ohshima, S, Santa, R, Mochiji, K, Goto, Y, Ikegami, T, Nagai, K, Kato, D, Takeo, M, Higuchi, Y. | Deposit date: | 2011-04-04 | Release date: | 2011-12-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Three-dimensional structure of nylon hydrolase and mechanism of nylon-6 hydrolysis J.Biol.Chem., 287, 2012
|
|
2DTJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2dtj by Molmil](/molmil-images/mine/2dtj) | Crystal structure of regulatory subunit of aspartate kinase from Corynebacterium glutamicum | Descriptor: | Aspartokinase, CITRIC ACID, THREONINE | Authors: | Yoshida, A, Tomita, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M. | Deposit date: | 2006-07-12 | Release date: | 2007-05-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Structural Insight into Concerted Inhibition of alpha(2)beta(2)-Type Aspartate Kinase from Corynebacterium glutamicum J.Mol.Biol., 368, 2007
|
|
2E3V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2e3v by Molmil](/molmil-images/mine/2e3v) | Crystal structure of the first fibronectin type III domain of neural cell adhesion molecule splicing isoform from human muscle culture lambda-4.4 | Descriptor: | 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Nishino, A, Saijo, S, Kishishita, S, Chen, L, Liu, Z.J, Wang, B.C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-11-30 | Release date: | 2007-06-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of the first fibronectin type III domain of neural cell adhesion molecule splicing isoform from human muscle culture lambda-4.4 To be Published
|
|
2EDZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2edz by Molmil](/molmil-images/mine/2edz) | Solution structures of the PDZ domain of mus musculus PDZ domain-containing protein 1 | Descriptor: | PDZ domain-containing protein 1 | Authors: | Sato, M, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-15 | Release date: | 2008-01-29 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structures of the PDZ domain of mus musculus PDZ domain-containing protein 1 To be Published
|
|
2EEC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2eec by Molmil](/molmil-images/mine/2eec) | Solution structure of the 23th filamin domain from human Filamin-B | Descriptor: | Filamin-B | Authors: | Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-15 | Release date: | 2007-08-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the 23th filamin domain from human Filamin-B To be Published
|
|
6A3I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6a3i by Molmil](/molmil-images/mine/6a3i) | Levoglucosan dehydrogenase, complex with NADH and levoglucosan | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Levoglucosan, Putative dehydrogenase | Authors: | Sugiura, M, Yamada, C, Arakawa, T, Fushinobu, S. | Deposit date: | 2018-06-15 | Release date: | 2018-09-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Identification, functional characterization, and crystal structure determination of bacterial levoglucosan dehydrogenase. J. Biol. Chem., 293, 2018
|
|
2ELJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2elj by Molmil](/molmil-images/mine/2elj) | Solution structure of the SWIRM domain of baker's yeast Transcriptional adapter 2 | Descriptor: | Transcriptional adapter 2 | Authors: | Yoneyama, M, Tochio, N, Koshiba, S, Tomizawa, T, Watanabe, S, Harada, T, Umehara, T, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-27 | Release date: | 2007-10-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the SWIRM domain of baker's yeast Transcriptional adapter 2 To be Published
|
|
2E6J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2e6j by Molmil](/molmil-images/mine/2e6j) | Solution structure of the C-terminal PapD-like domain from human HYDIN protein | Descriptor: | HYDIN protein | Authors: | Li, H, Sato, M, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-12-27 | Release date: | 2007-07-03 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the C-terminal PapD-like domain from human HYDIN protein To be Published
|
|
6A3F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6a3f by Molmil](/molmil-images/mine/6a3f) | Levoglucosan dehydrogenase, apo form | Descriptor: | Putative dehydrogenase, SULFATE ION | Authors: | Sugiura, M, Yamada, C, Arakawa, T, Fushinobu, S. | Deposit date: | 2018-06-15 | Release date: | 2018-09-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Identification, functional characterization, and crystal structure determination of bacterial levoglucosan dehydrogenase. J. Biol. Chem., 293, 2018
|
|
2EA6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ea6 by Molmil](/molmil-images/mine/2ea6) | Solution Structure of the RING domain of the human ring finger protein 4 | Descriptor: | RING finger protein 4, ZINC ION | Authors: | Miyamoto, K, Yoneyama, M, Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-30 | Release date: | 2007-07-31 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution Structure of the RING domain of the human ring finger protein 4 To be Published
|
|
2EDY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2edy by Molmil](/molmil-images/mine/2edy) | Solution structures of the fn3 domain of human receptor-type tyrosine-protein phosphatase F | Descriptor: | Receptor-type tyrosine-protein phosphatase F | Authors: | Sato, M, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-15 | Release date: | 2007-08-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structures of the fn3 domain of human receptor-type tyrosine-protein phosphatase F To be Published
|
|
2EE4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ee4 by Molmil](/molmil-images/mine/2ee4) | Solution structure of the RhoGAP domain from human Rho GTPase activating protein 5 variant | Descriptor: | Rho GTPase activating protein 5 variant | Authors: | Tomizawa, T, Tochio, N, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-15 | Release date: | 2007-08-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the RhoGAP domain from human Rho GTPase activating protein 5 variant To be Published
|
|
2ELR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2elr by Molmil](/molmil-images/mine/2elr) | Solution structure of the 15th C2H2 zinc finger of human Zinc finger protein 406 | Descriptor: | ZINC ION, Zinc finger protein 406 | Authors: | Tochio, N, Yoneyama, M, Koshiba, S, Watanabe, S, Harada, T, Umehara, T, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-27 | Release date: | 2008-04-01 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the 15th C2H2 zinc finger of human Zinc finger protein 406 To be Published
|
|
2DZI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2dzi by Molmil](/molmil-images/mine/2dzi) | 2DZI/Solution Structure of the N-terminal Ubiquitin-like Domain in Human Ubiquitin-like Protein 4A (GDX) | Descriptor: | Ubiquitin-like protein 4A | Authors: | Zhao, C, Sato, M, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-09-29 | Release date: | 2007-03-29 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | 2DZI/Solution Structure of the N-terminal Ubiquitin-like Domain in Human Ubiquitin-like Protein 4A (GDX) To be Published
|
|
2ELH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2elh by Molmil](/molmil-images/mine/2elh) | Solution structure of the CENP-B N-terminal DNA-binding domain of fruit fly distal antenna CG11849-PA | Descriptor: | CG11849-PA | Authors: | Tochio, N, Koshiba, S, Watanabe, S, Harada, T, Umehara, T, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-27 | Release date: | 2008-04-01 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the CENP-B N-terminal DNA-binding domain of fruit fly distal antenna CG11849-PA To be Published
|
|
2E9G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2e9g by Molmil](/molmil-images/mine/2e9g) | Solution structure of the alpha adaptinC2 domain from human Adapter-related protein complex 1 gamma 2 subunit | Descriptor: | AP-1 complex subunit gamma-2 | Authors: | Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-25 | Release date: | 2007-07-31 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the alpha adaptinC2 domain from human Adapter-related protein complex 1 gamma 2 subunit To be Published
|
|
2ECJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ecj by Molmil](/molmil-images/mine/2ecj) | Solution structure of the RING domain of the human tripartite motif-containing protein 39 | Descriptor: | Tripartite motif-containing protein 39, ZINC ION | Authors: | Miyamoto, K, Sato, M, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-13 | Release date: | 2007-08-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the RING domain of the human tripartite motif-containing protein 39 To be Published
|
|