4IDM
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4IHI
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6BNU
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1CGP
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![BU of 1cgp by Molmil](/molmil-images/mine/1cgp) | CATABOLITE GENE ACTIVATOR PROTEIN (CAP)/DNA COMPLEX + ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA (5'-D(*GP*CP*GP*AP*AP*AP*AP*GP*TP*GP*TP*GP*AP*CP*AP*TP*AP*T)-3'), DNA (5'-D(*GP*TP*CP*AP*CP*AP*CP*TP*TP*TP*TP*CP*G)-3'), ... | Authors: | Schultz, S.C, Shields, G.C, Steitz, T.A. | Deposit date: | 1991-08-12 | Release date: | 1994-01-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of a CAP-DNA complex: the DNA is bent by 90 degrees. Science, 253, 1991
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4JDC
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3T9I
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![BU of 3t9i by Molmil](/molmil-images/mine/3t9i) | Pim1 complexed with a novel 3,6-disubstituted indole at 2.6 Ang Resolution | Descriptor: | 2-methoxy-4-(3-phenyl-2H-pyrazolo[3,4-b]pyridin-6-yl)phenol, Proto-oncogene serine/threonine-protein kinase pim-1 | Authors: | Bellamacina, C, Shu, W, Le, V, Nishiguchi, G, Bussiere, D. | Deposit date: | 2011-08-02 | Release date: | 2011-10-12 | Last modified: | 2011-11-02 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Discovery of novel 3,5-disubstituted indole derivatives as potent inhibitors of Pim-1, Pim-2, and Pim-3 protein kinases. Bioorg.Med.Chem.Lett., 21, 2011
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3JBK
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![BU of 3jbk by Molmil](/molmil-images/mine/3jbk) | Cryo-EM reconstruction of the metavinculin-actin interface | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Kim, L.Y, Thompson, P.M, Lee, H.T, Pershad, M, Campbell, S.L, Alushin, G.M. | Deposit date: | 2015-09-03 | Release date: | 2015-11-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (8.2 Å) | Cite: | The Structural Basis of Actin Organization by Vinculin and Metavinculin. J.Mol.Biol., 428, 2016
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3JBI
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![BU of 3jbi by Molmil](/molmil-images/mine/3jbi) | MDFF model of the vinculin tail domain bound to F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Kim, L.Y, Thompson, P.M, Lee, H.T, Pershad, M, Campbell, S.L, Alushin, G.M. | Deposit date: | 2015-09-02 | Release date: | 2015-11-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (8.5 Å) | Cite: | The Structural Basis of Actin Organization by Vinculin and Metavinculin. J.Mol.Biol., 428, 2016
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4LEM
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1MI4
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![BU of 1mi4 by Molmil](/molmil-images/mine/1mi4) | Glyphosate insensitive G96A mutant EPSP synthase liganded with shikimate-3-phosphate | Descriptor: | 5-enolpyruvylshikimate-3-phosphate synthase, FORMIC ACID, SHIKIMATE-3-PHOSPHATE | Authors: | Eschenburg, S, Healy, M.L, Priestman, M.A, Lushington, G.H, Schonbrunn, E. | Deposit date: | 2002-08-21 | Release date: | 2002-12-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | How the mutation glycine96 to alanine confers glyphosate insensitivity to 5-enolpyruvyl
shikimate-3-phosphate synthase from Escherichia coli. PLANTA, 216, 2002
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1G9V
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![BU of 1g9v by Molmil](/molmil-images/mine/1g9v) | HIGH RESOLUTION CRYSTAL STRUCTURE OF DEOXY HEMOGLOBIN COMPLEXED WITH A POTENT ALLOSTERIC EFFECTOR | Descriptor: | 2-{4-[(3,5-DIMETHYLANILINO)-CARBONYL-METHYL]-PHENOXY}-2-METHYLPROPIONIC ACID, HEMOGLOBIN ALPHA CHAIN, HEMOGLOBIN BETA CHAIN, ... | Authors: | Safo, M.K, Moure, C.M, Burnett, J.C, Joshi, G.S, Abraham, D.J. | Deposit date: | 2000-11-28 | Release date: | 2000-12-06 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | High-resolution crystal structure of deoxy hemoglobin complexed with a potent allosteric effector. Protein Sci., 10, 2001
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4NS3
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1K0Y
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![BU of 1k0y by Molmil](/molmil-images/mine/1k0y) | X-ray Crystallographic Analyses of Symmetrical Allosteric Effectors of Hemoglobin. Compounds Designed to Link Primary and Secondary Binding Sites | Descriptor: | 2-{4-[(3{2-[4-(1-CARBOXY-1-METHYL-ETHOXY)-PHENYL]-ACETYLAMINO}-PHENYLCARBAMOYL)-METHYL]-PHENOXY}-2-METHYL-PROPIONIC ACID, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... | Authors: | Safo, M.K, Boyiri, T, Burnett, J.C, Danso-Danquah, R, Moure, C.M, Joshi, G.S, Abraham, D.J. | Deposit date: | 2001-09-21 | Release date: | 2001-10-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | X-ray crystallographic analyses of symmetrical allosteric effectors of hemoglobin: compounds designed to link primary and secondary binding sites. Acta Crystallogr.,Sect.D, 58, 2002
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3JBJ
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![BU of 3jbj by Molmil](/molmil-images/mine/3jbj) | Cryo-EM reconstruction of F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Kim, L.Y, Thompson, P.M, Lee, H.T, Pershad, M, Campbell, S.L, Alushin, G.M. | Deposit date: | 2015-09-03 | Release date: | 2015-11-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (7.6 Å) | Cite: | The Structural Basis of Actin Organization by Vinculin and Metavinculin. J.Mol.Biol., 428, 2016
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3JZI
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![BU of 3jzi by Molmil](/molmil-images/mine/3jzi) | Crystal structure of biotin carboxylase from E. Coli in complex with benzimidazole series | Descriptor: | 7-amino-2-[(2-chlorobenzyl)amino]-1-{[(1S,2S)-2-hydroxycycloheptyl]methyl}-1H-benzimidazole-5-carboxamide, Biotin carboxylase | Authors: | Cheng, C, Shipps, G.W, Yang, Z, Sun, B, Kawahata, N, Soucy, K, Soriano, A, Orth, P, Xiao, L, Mann, P, Black, T. | Deposit date: | 2009-09-23 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Discovery and optimization of antibacterial AccC inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
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5ZDP
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![BU of 5zdp by Molmil](/molmil-images/mine/5zdp) | Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ferulenol | Descriptor: | 4-oxidanyl-3-[(2~{E},6~{E})-3,7,11-trimethyldodeca-2,6,10-trienyl]chromen-2-one, Alternative oxidase, mitochondrial, ... | Authors: | Shiba, T, Inaoka, D.K, Takahashi, G, Tsuge, C, Kido, Y, Young, L, Ueda, S, Balogun, E.O, Nara, T, Honma, T, Tanaka, A, Inoue, M, Saimoto, H, Harada, S, Moore, A.L, Kita, K. | Deposit date: | 2018-02-23 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Insights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase. Biochim Biophys Acta Bioenerg, 1860, 2019
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3W54
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![BU of 3w54 by Molmil](/molmil-images/mine/3w54) | Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with colletochlorin B | Descriptor: | 3-chloro-5-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-4,6-dihydroxy-2-methylbenzaldehyde, Alternative oxidase, mitochondrial, ... | Authors: | Shiba, T, Kido, Y, Sakamoto, K, Inaoka, D.K, Tsuge, C, Tatsumi, R, Takahashi, G, Balogun, E.O, Nara, T, Aoki, T, Honma, T, Tanaka, A, Inoue, M, Matsuoka, S, Saimoto, H, Moore, A.L, Harada, S, Kita, K. | Deposit date: | 2013-01-21 | Release date: | 2013-03-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the trypanosome cyanide-insensitive alternative oxidase Proc.Natl.Acad.Sci.USA, 110, 2013
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7UDU
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![BU of 7udu by Molmil](/molmil-images/mine/7udu) | cryo-EM structure of the ADP state wild type myosin-15-F-actin complex (symmetry expansion and re-centering) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Gong, R, Reynolds, M.J, Alushin, G.M. | Deposit date: | 2022-03-20 | Release date: | 2022-08-03 | Method: | ELECTRON MICROSCOPY (4.15 Å) | Cite: | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia. Sci Adv, 8, 2022
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7UDT
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![BU of 7udt by Molmil](/molmil-images/mine/7udt) | cryo-EM structure of the rigor state wild type myosin-15-F-actin complex (symmetry expansion and re-centering) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Gong, R, Reynolds, M.J, Alushin, G.M. | Deposit date: | 2022-03-20 | Release date: | 2022-08-03 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia. Sci Adv, 8, 2022
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1QXE
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![BU of 1qxe by Molmil](/molmil-images/mine/1qxe) | Structural Basis for the Potent Antisickling Effect of a Novel Class of 5-Membered Heterocyclic Aldehydic Compounds | Descriptor: | 5-HYDROXYMETHYL-FURFURAL, Hemoglobin alpha chain, Hemoglobin beta chain, ... | Authors: | Safo, M.K, Abdulmalik, O, Danso-Danquah, R, Nokuri, S, Joshi, G.S, Musayev, F.N, Asakura, T, Abraham, D.J. | Deposit date: | 2003-09-05 | Release date: | 2003-09-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis for the potent antisickling effect of a novel class of five-membered heterocyclic aldehydic compounds J.Med.Chem., 47, 2004
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1QXD
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![BU of 1qxd by Molmil](/molmil-images/mine/1qxd) | Structural Basis for the Potent Antisickling Effect of a Novel Class of 5-Membered Heterocyclic Aldehydic Compounds | Descriptor: | FURFURAL, Hemoglobin alpha chain, Hemoglobin beta chain, ... | Authors: | Safo, M.K, Abdulmalik, O, Danso-Danquah, R, Nokuri, S, Joshi, G.S, Musayev, F.N, Asakura, T, Abraham, D.J. | Deposit date: | 2003-09-05 | Release date: | 2003-09-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural basis for the potent antisickling effect of a novel class of five-membered heterocyclic aldehydic compounds J.Med.Chem., 47, 2004
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1X26
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![BU of 1x26 by Molmil](/molmil-images/mine/1x26) | Solution structure of the AA-mismatch DNA complexed with naphthyridine-azaquinolone | Descriptor: | 5'-D(*CP*AP*TP*TP*CP*AP*GP*TP*TP*AP*G)-3', 5'-D(*CP*TP*AP*AP*CP*AP*GP*AP*AP*TP*G)-3', N~3~-{3-[(7-METHYL-1,8-NAPHTHYRIDIN-2-YL)AMINO]-3-OXOPROPYL}-N~1~-[(7-OXO-7,8-DIHYDRO-1,8-NAPHTHYRIDIN-2-YL)METHYL]-BET A-ALANINAMIDE | Authors: | Nakatani, K, Hagihara, S, Goto, Y, Kobori, A, Hagihara, M, Hayashi, G, Kyo, M, Nomura, M, Mishima, M, Kojima, C. | Deposit date: | 2005-04-20 | Release date: | 2006-04-04 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Small-molecule ligand induces nucleotide flipping in (CAG)n trinucleotide repeats Nat.Chem.Biol., 1, 2005
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