3WHP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3whp by Molmil](/molmil-images/mine/3whp) | Crystal structure of the C-terminal domain of Themus thermophilus LitR in complex with cobalamin | Descriptor: | COBALAMIN, Probable transcriptional regulator | Authors: | Agari, Y, Takano, H, Beppu, T, Ueda, K, Shinkai, A. | Deposit date: | 2013-08-30 | Release date: | 2014-09-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Crystal structure of the C-terminal domain of Themus thermophilus LitR in complex with cobalamin To be Published
|
|
3WPY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wpy by Molmil](/molmil-images/mine/3wpy) | Microbacterium saccharophilum K-1 beta-fructofuranosidase mutant T47S/S200T/F447V/P500S | Descriptor: | Beta-fructofuranosidase | Authors: | Yokoi, G, Mori, M, Sato, S, Miyazaki, T, Nishikawa, A, Tonozuka, T. | Deposit date: | 2014-01-17 | Release date: | 2014-03-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Enhancing thermostability and the structural characterization of Microbacterium saccharophilum K-1 beta-fructofuranosidase Appl.Microbiol.Biotechnol., 98, 2014
|
|
3WPZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wpz by Molmil](/molmil-images/mine/3wpz) | Microbacterium saccharophilum K-1 beta-fructofuranosidase mutant T47S/S200T/F447P/F470Y/P500S | Descriptor: | Beta-fructofuranosidase | Authors: | Yokoi, G, Mori, M, Sato, S, Miyazaki, T, Nishikawa, A, Tonozuka, T. | Deposit date: | 2014-01-17 | Release date: | 2014-03-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Enhancing thermostability and the structural characterization of Microbacterium saccharophilum K-1 beta-fructofuranosidase Appl.Microbiol.Biotechnol., 98, 2014
|
|
1SF8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1sf8 by Molmil](/molmil-images/mine/1sf8) | Crystal structure of the carboxy-terminal domain of htpG, the E. coli Hsp90 | Descriptor: | CHLORIDE ION, Chaperone protein htpG, NICKEL (II) ION | Authors: | Harris, S.F, Shiau, A.K, Agard, D.A. | Deposit date: | 2004-02-19 | Release date: | 2004-06-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The crystal structure of the carboxy-terminal dimerization domain of htpG, the Escherichia coli Hsp90, reveals a potential substrate binding site. Structure, 12, 2004
|
|
7VBU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vbu by Molmil](/molmil-images/mine/7vbu) | Crystal structure of human pyruvate dehydrogenase kinase 2 in complex with compound 5 | Descriptor: | 8-cyclopropyl-2-methyl-9H-pyrido[2,3-b]indole, ACETATE ION, CHLORIDE ION, ... | Authors: | Orita, T, Doi, S, Iwanaga, T, Fujishima, A, Adachi, T. | Deposit date: | 2021-09-01 | Release date: | 2022-02-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structure-based drug design of novel and highly potent pyruvate dehydrogenase kinase inhibitors. Bioorg.Med.Chem., 52, 2021
|
|
1VB9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1vb9 by Molmil](/molmil-images/mine/1vb9) | Crystal structure of Thermoactinomyces vulgaris R-47 alpha-amylase II (TVA II) complexed with transglycosylated product | Descriptor: | CALCIUM ION, alpha-D-glucopyranose-(1-6)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-[alpha-D-glucopyranose-(1-6)]alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-amylase II | Authors: | Mizuno, M, Tonozuka, T, Uechi, A, Ohtaki, A, Ichikawa, K, Kamitori, S, Nishikawa, A, Sakano, Y. | Deposit date: | 2004-02-25 | Release date: | 2005-03-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The crystal structure of Thermoactinomyces vulgaris R-47 alpha-amylase II (TVA II) complexed with transglycosylated product EUR.J.BIOCHEM., 271, 2004
|
|
2Z8G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2z8g by Molmil](/molmil-images/mine/2z8g) | Aspergillus niger ATCC9642 isopullulanase complexed with isopanose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Isopullulanase, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-6)-beta-D-glucopyranose | Authors: | Mizuno, M, Koide, A, Yamamura, A, Akeboshi, H, Yoshida, H, Kamitori, S, Sakano, Y, Nishikawa, A, Tonozuka, T. | Deposit date: | 2007-09-05 | Release date: | 2007-12-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of Aspergillus niger Isopullulanase, a Member of Glycoside Hydrolase Family 49 J.Mol.Biol., 376, 2008
|
|
7Y13
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y13 by Molmil](/molmil-images/mine/7y13) | Cryo-EM structure of apo-state MrgD-Gi complex (local) | Descriptor: | PALMITIC ACID, Soluble cytochrome b562,Mas-related G-protein coupled receptor member D | Authors: | Suzuki, S, Iida, M, Kawamoto, A, Oshima, A. | Deposit date: | 2022-06-06 | Release date: | 2022-07-20 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insight into the activation mechanism of MrgD with heterotrimeric Gi-protein revealed by cryo-EM. Commun Biol, 5, 2022
|
|
7Y12
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y12 by Molmil](/molmil-images/mine/7y12) | Cryo-EM structure of MrgD-Gi complex with beta-alanine | Descriptor: | BETA-ALANINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Suzuki, S, Iida, M, Kawamoto, A, Oshima, A. | Deposit date: | 2022-06-06 | Release date: | 2022-07-20 | Last modified: | 2023-02-15 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insight into the activation mechanism of MrgD with heterotrimeric Gi-protein revealed by cryo-EM. Commun Biol, 5, 2022
|
|
7Y14
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y14 by Molmil](/molmil-images/mine/7y14) | Cryo-EM structure of MrgD-Gi complex with beta-alanine (local) | Descriptor: | BETA-ALANINE, PALMITIC ACID, Soluble cytochrome b562,Mas-related G-protein coupled receptor member D | Authors: | Suzuki, S, Iida, M, Kawamoto, A, Oshima, A. | Deposit date: | 2022-06-06 | Release date: | 2022-07-20 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural insight into the activation mechanism of MrgD with heterotrimeric Gi-protein revealed by cryo-EM. Commun Biol, 5, 2022
|
|
7Y15
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y15 by Molmil](/molmil-images/mine/7y15) | Cryo-EM structure of apo-state MrgD-Gi complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Suzuki, S, Iida, M, Kawamoto, A, Oshima, A. | Deposit date: | 2022-06-06 | Release date: | 2022-07-20 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural insight into the activation mechanism of MrgD with heterotrimeric Gi-protein revealed by cryo-EM. Commun Biol, 5, 2022
|
|
7VBV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vbv by Molmil](/molmil-images/mine/7vbv) | Crystal structure of human pyruvate dehydrogenase kinase 2 in complex with compound 7 | Descriptor: | ACETATE ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | Authors: | Orita, T, Doi, S, Iwanaga, T, Fujishima, A, Adachi, T. | Deposit date: | 2021-09-01 | Release date: | 2022-02-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structure-based drug design of novel and highly potent pyruvate dehydrogenase kinase inhibitors. Bioorg.Med.Chem., 52, 2021
|
|
1X2J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x2j by Molmil](/molmil-images/mine/1x2j) | Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2 | Descriptor: | Kelch-like ECH-associated protein 1, SULFATE ION | Authors: | Padmanabhan, B, Tong, K.I, Nakamura, Y, Ohta, T, Scharlock, M, Kobayashi, A, Ohtsuji, M, Kang, M.-I, Yamamoto, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-04-25 | Release date: | 2006-03-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis for defects of keap1 activity provoked by its point mutations in lung cancer Mol.Cell, 21, 2006
|
|
1X2R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x2r by Molmil](/molmil-images/mine/1x2r) | Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2 | Descriptor: | Kelch-like ECH-associated protein 1, Nuclear factor erythroid 2 related factor 2, SULFATE ION | Authors: | Padmanabhan, B, Tong, K.I, Nakamura, Y, Ohta, T, Scharlock, M, Kobayashi, A, Ohtsuji, M, Kang, M.-I, Yamamoto, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-04-26 | Release date: | 2006-03-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for defects of keap1 activity provoked by its point mutations in lung cancer Mol.Cell, 21, 2006
|
|
3A3U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3a3u by Molmil](/molmil-images/mine/3a3u) | Crystal structure of MqnD (TTHA1568), a menaquinone biosynthetic enzyme from Thermus thermophilus HB8 | Descriptor: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, L(+)-TARTARIC ACID, Menaquinone biosynthetic enzyme, ... | Authors: | Arai, R, Nishino, A, Nagano, K, Uchikubo-Kamo, T, Katsura, K, Nishimoto, M, Toyama, M, Terada, T, Kuramitsu, S, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2009-06-20 | Release date: | 2009-07-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of MqnD (TTHA1568), a menaquinone biosynthetic enzyme from Thermus thermophilus HB8. J.Struct.Biol., 168, 2009
|
|
1UG9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ug9 by Molmil](/molmil-images/mine/1ug9) | Crystal Structure of Glucodextranase from Arthrobacter globiformis I42 | Descriptor: | CALCIUM ION, GLYCEROL, glucodextranase | Authors: | Mizuno, M, Tonozuka, T, Suzuki, S, Uotsu-Tomita, R, Ohtaki, A, Kamitori, S, Nishikawa, A, Sakano, Y. | Deposit date: | 2003-06-16 | Release date: | 2003-12-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into substrate specificity and function of glucodextranase J.Biol.Chem., 279, 2004
|
|
5OL8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ol8 by Molmil](/molmil-images/mine/5ol8) | Structure of human mitochondrial transcription elongation factor (TEFM) C-terminal domain | Descriptor: | GLYCEROL, Transcription elongation factor, mitochondrial | Authors: | Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D. | Deposit date: | 2017-07-27 | Release date: | 2017-10-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanism of Transcription Anti-termination in Human Mitochondria. Cell, 171, 2017
|
|
1ULV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ulv by Molmil](/molmil-images/mine/1ulv) | Crystal Structure of Glucodextranase Complexed with Acarbose | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, CALCIUM ION, glucodextranase | Authors: | Mizuno, M, Tonozuka, T, Suzuki, S, Uotsu-Tomita, R, Kamitori, S, Nishikawa, A, Sakano, Y. | Deposit date: | 2003-09-16 | Release date: | 2003-12-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Structural insights into substrate specificity and function of glucodextranase J.Biol.Chem., 279, 2004
|
|
1SPX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1spx by Molmil](/molmil-images/mine/1spx) | Crystal Structure of Glucose Dehydrogenase of Caenorhabditis Elegans in the Apo-Form | Descriptor: | short-chain reductase family member (5L265) | Authors: | Schormann, N, Zhou, J, McCombs, D, Bray, T, Symersky, J, Huang, W.-Y, Luan, C.-H, Gray, R, Luo, D, Arabashi, A, Bunzel, B, Nagy, L, Lu, S, Li, S, Lin, G, Zhang, Y, Qiu, S, Tsao, J, Luo, M, Carson, M, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2004-03-17 | Release date: | 2004-03-23 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of Glucose Dehydrogenase of Caenorhabditis Elegans in the Apo-Form: A Member of the SDR-Family To be Published
|
|
1T9F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1t9f by Molmil](/molmil-images/mine/1t9f) | Structural genomics of Caenorhabditis elegans: Structure of a protein with unknown function | Descriptor: | MALONATE ION, protein 1d10 | Authors: | Symersky, J, Li, S, Bunzel, R, Schormann, N, Luo, D, Huang, W.Y, Qiu, S, Gray, R, Zhang, Y, Arabashi, A, Lu, S, Luan, C.H, Tsao, J, DeLucas, L, Luo, M, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2004-05-16 | Release date: | 2004-05-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural genomics of Caenorhabditis elegans: Structure of a protein with unknown function. To be Published
|
|
7WT1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wt1 by Molmil](/molmil-images/mine/7wt1) | |
5OL9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ol9 by Molmil](/molmil-images/mine/5ol9) | Structure of human mitochondrial transcription elongation factor (TEFM) N-terminal domain | Descriptor: | ACETATE ION, Transcription elongation factor, mitochondrial | Authors: | Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D. | Deposit date: | 2017-07-27 | Release date: | 2017-10-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.302 Å) | Cite: | Mechanism of Transcription Anti-termination in Human Mitochondria. Cell, 171, 2017
|
|
5OLA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ola by Molmil](/molmil-images/mine/5ola) | Structure of mitochondrial transcription elongation complex in complex with elongation factor TEFM | Descriptor: | DNA (30-MER), DNA (5'-D(P*AP*TP*GP*GP*TP*GP*TP*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*GP*AP*AP*C)-3'), DNA-directed RNA polymerase, ... | Authors: | Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D. | Deposit date: | 2017-07-27 | Release date: | 2017-10-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.904 Å) | Cite: | Mechanism of Transcription Anti-termination in Human Mitochondria. Cell, 171, 2017
|
|
1ROW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1row by Molmil](/molmil-images/mine/1row) | Structure of SSP-19, an MSP-domain protein like family member in Caenorhabditis elegans | Descriptor: | MSP-domain protein like family member | Authors: | Schormann, N, Symersky, J, Carson, M, Luo, M, Lin, G, Li, S, Qiu, S, Arabashi, A, Bunzel, B, Luo, D, Nagy, L, Gray, R, Luan, C.-H, Zhang, J, Lu, S, DeLucas, L, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2003-12-02 | Release date: | 2003-12-23 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of sperm-specific protein SSP-19 from Caenorhabditis elegans. Acta Crystallogr.,Sect.D, 60, 2004
|
|
3D3I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d3i by Molmil](/molmil-images/mine/3d3i) | Crystal structural of Escherichia coli K12 YgjK, a glucosidase belonging to glycoside hydrolase family 63 | Descriptor: | CALCIUM ION, GLYCEROL, Uncharacterized protein ygjK | Authors: | Kurakata, Y, Uechi, A, Yoshida, H, Kamitori, S, Sakano, Y, Nishikawa, A, Tonozuka, T. | Deposit date: | 2008-05-12 | Release date: | 2008-06-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structural insights into the substrate specificity and function of Escherichia coli K12 YgjK, a glucosidase belonging to the glycoside hydrolase family 63. J.Mol.Biol., 381, 2008
|
|