3EDT
 
 | | Crystal structure of the mutated S328N hKLC2 TPR domain | | 分子名称: | Kinesin light chain 2, UNKNOWN ATOM OR ION | | 著者 | Zhu, H, Shen, Y, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2008-09-03 | | 公開日 | 2009-02-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of mutated S328N TPR domain of human kinesin light chain 2
To be published
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4EJS
 | | Structure of yeast elongator subcomplex Elp456 | | 分子名称: | Elongator complex protein 4, Elongator complex protein 5, Elongator complex protein 6 | | 著者 | Lin, Z, Zhao, W, Long, J, Shen, Y. | | 登録日 | 2012-04-07 | | 公開日 | 2012-05-02 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.606 Å) | | 主引用文献 | Crystal structure of elongator subcomplex Elp4-6
J.Biol.Chem., 287, 2012
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6URP
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6W6D
 | | Crystal Structure of Human Protein arginine N-methyltransferase 6 (PRMT6) in complex with SGC6870 inhibitor | | 分子名称: | (5R)-4-(5-bromothiophene-2-carbonyl)-5-(3,5-dimethylphenyl)-7-methyl-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one, Protein arginine N-methyltransferase 6, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Halabelian, L, Zeng, H, Dong, A, Jin, J, Shen, Y, Kaniskan, H.U, Hutchinson, A, Seitova, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Brown, P.J, Structural Genomics Consortium (SGC) | | 登録日 | 2020-03-16 | | 公開日 | 2020-04-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6.
J.Med.Chem., 64, 2021
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1KQM
 | | SCALLOP MYOSIN S1-AMPPNP IN THE ACTIN-DETACHED CONFORMATION | | 分子名称: | CALCIUM ION, MAGNESIUM ION, MYOSIN ESSENTIAL LIGHT CHAIN, ... | | 著者 | Himmel, D.M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, G, Cohen, C. | | 登録日 | 2002-01-07 | | 公開日 | 2002-11-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystallographic findings on the
internally uncoupled and near-rigor
states of myosin: Further insights into
the mechanics of the motor
Proc.Natl.Acad.Sci.USA, 99, 2002
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1L2O
 | | SCALLOP MYOSIN S1-ADP-p-PDM IN THE ACTIN-DETACHED CONFORMATION | | 分子名称: | 4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | | 著者 | Himmel, M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, G, Cohen, C. | | 登録日 | 2002-02-22 | | 公開日 | 2002-10-30 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1KK8
 | | SCALLOP MYOSIN (S1-ADP-BeFx) IN THE ACTIN-DETACHED CONFORMATION | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, ... | | 著者 | Himmel, M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, G, Cohen, C. | | 登録日 | 2001-12-06 | | 公開日 | 2002-10-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1KK7
 | | SCALLOP MYOSIN IN THE NEAR RIGOR CONFORMATION | | 分子名称: | CALCIUM ION, MAGNESIUM ION, MYOSIN ESSENTIAL LIGHT CHAIN, ... | | 著者 | Himmel, D.M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, A.G, Cohen, C. | | 登録日 | 2001-12-06 | | 公開日 | 2002-10-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1KWO
 | | SCALLOP MYOSIN S1-ATPgammaS-p-PDM IN THE ACTIN-DETACHED CONFORMATION | | 分子名称: | 4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID, CALCIUM ION, MAGNESIUM ION, ... | | 著者 | Himmel, D.M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, G, Cohen, C. | | 登録日 | 2002-01-30 | | 公開日 | 2002-11-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Crystallographic findings on the
internally uncoupled and near-rigor
states of myosin: Further insights into
the mechanics of the motor
Proc.Natl.Acad.Sci.USA, 99, 2002
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3GXA
 | | Crystal structure of GNA1946 | | 分子名称: | METHIONINE, Outer membrane lipoprotein GNA1946, SULFATE ION | | 著者 | Yang, X, Shen, Y. | | 登録日 | 2009-04-02 | | 公開日 | 2009-10-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal structure of lipoprotein GNA1946 from Neisseria meningitidis
J.Struct.Biol., 168, 2009
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1TE7
 | | Solution NMR Structure of Protein yqfB from Escherichia coli. Northeast Structural Genomics Consortium Target ET99 | | 分子名称: | Hypothetical UPF0267 protein yqfB | | 著者 | Atreya, H.S, Shen, Y, Yee, A, Arrowsmith, C, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2004-05-24 | | 公開日 | 2005-01-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | G-Matrix Fourier Transform NOESY-Based Protocol for High-Quality Protein Structure Determination
J.Am.Chem.Soc., 127, 2005
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3CBQ
 | | Crystal structure of the human REM2 GTPase with bound GDP | | 分子名称: | 1,2-ETHANEDIOL, GTP-binding protein REM 2, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Nedyalkova, L, Shen, Y, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2008-02-22 | | 公開日 | 2008-03-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Crystal structure of the human REM2 GTPase with bound GDP.
To be Published
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1SK6
 | | Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin, 3',5' cyclic AMP (cAMP), and pyrophosphate | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CALCIUM ION, Calmodulin, ... | | 著者 | Guo, Q, Shen, Y, Zhukovskaya, N.L, Tang, W.J. | | 登録日 | 2004-03-04 | | 公開日 | 2004-06-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural and kinetic analyses of the interaction of anthrax adenylyl cyclase toxin with reaction products cAMP and pyrophosphate.
J.Biol.Chem., 279, 2004
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1MI1
 | | Crystal Structure of the PH-BEACH Domain of Human Neurobeachin | | 分子名称: | Neurobeachin | | 著者 | Jogl, G, Shen, Y, Gebauer, D, Li, J, Wiegmann, K, Kashkar, H, Kroenke, M, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2002-08-21 | | 公開日 | 2002-09-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain.
EMBO J., 21, 2002
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1T77
 | | Crystal structure of the PH-BEACH domains of human LRBA/BGL | | 分子名称: | Lipopolysaccharide-responsive and beige-like anchor protein | | 著者 | Gebauer, D, Li, J, Jogl, G, Shen, Y, Myszka, D.G, Tong, L. | | 登録日 | 2004-05-08 | | 公開日 | 2004-12-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of the PH-BEACH Domains of Human LRBA/BGL
Biochemistry, 43, 2004
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1YRT
 | | Crystal Structure analysis of the adenylyl cyclaes catalytic domain of adenylyl cyclase toxin of Bordetella pertussis in presence of c-terminal calmodulin | | 分子名称: | Bifunctional hemolysin-adenylate cyclase, CALCIUM ION, Calmodulin | | 著者 | Guo, Q, Shen, Y, Lee, Y.S, Gibbs, C.S, Mrksich, M, Tang, W.J. | | 登録日 | 2005-02-04 | | 公開日 | 2006-01-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin.
Embo J., 24, 2005
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1YRU
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5CQR
 | | Dimerization of Elp1 is essential for Elongator complex assembly | | 分子名称: | Elongator complex protein 1 | | 著者 | Lin, Z, Xu, H, Li, F, Diao, W, Long, J, Shen, Y. | | 登録日 | 2015-07-22 | | 公開日 | 2015-08-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.015 Å) | | 主引用文献 | Dimerization of elongator protein 1 is essential for Elongator complex assembly.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5CQS
 | | Dimerization of Elp1 is essential for Elongator complex assembly | | 分子名称: | Elongator complex protein 1 | | 著者 | Lin, Z, Xu, H, Li, F, Diao, W, Long, J, Shen, Y. | | 登録日 | 2015-07-22 | | 公開日 | 2015-08-19 | | 最終更新日 | 2020-02-19 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Dimerization of elongator protein 1 is essential for Elongator complex assembly.
Proc.Natl.Acad.Sci.USA, 112, 2015
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1XN5
 | | Solution Structure of Bacillus halodurans Protein BH1534: The Northeast Structural Genomics Consortium Target BhR29 | | 分子名称: | BH1534 unknown conserved protein | | 著者 | Liu, G, Ma, L, Shen, Y, Acton, T, Atreya, H.S, Xiao, R, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2004-10-04 | | 公開日 | 2004-12-14 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of Bacillus halodurans Protein BH1534: The Northeast Structural Genomics Consortium Target BhR29
To be Published
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1ZNV
 | | How a His-metal finger endonuclease ColE7 binds and cleaves DNA with a transition metal ion cofactor | | 分子名称: | Colicin E7, Colicin E7 immunity protein, NICKEL (II) ION, ... | | 著者 | Doudeva, L.G, Huang, H, Hsia, K.C, Shi, Z, Li, C.L, Shen, Y, Yuan, H.S. | | 登録日 | 2005-05-12 | | 公開日 | 2006-03-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structural analysis and metal-dependent stability and activity studies of the ColE7 endonuclease domain in complex with DNA/Zn2+ or inhibitor/Ni2+
Protein Sci., 15, 2006
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1YX0
 | | Solution Structure of Bacillus subtilis Protein ysnE: The Northeast Structural Genomics Consortium Target SR220 | | 分子名称: | hypothetical protein ysnE | | 著者 | Liu, G, Ma, L, Shen, Y, Xiao, R, Acton, T, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2005-02-18 | | 公開日 | 2005-03-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of Bacillus subtilis Protein ysnE
To be Published
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1ZTS
 | | Solution Structure of Bacillus Subtilis Protein YQBG: Northeast Structural Genomics Consortium Target SR215 | | 分子名称: | Hypothetical protein yqbG | | 著者 | Liu, G, Shen, Y, Xiao, R, Acton, T, Ma, L, Joachimiak, A, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2005-05-27 | | 公開日 | 2005-07-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of protein yqbG from Bacillus subtilis reveals a novel alpha-helical protein fold.
Proteins, 62, 2006
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1ZNS
 | | Crystal structure of N-ColE7/12-bp DNA/Zn complex | | 分子名称: | 5'-D(*CP*GP*GP*GP*AP*TP*AP*TP*CP*CP*CP*G)-3', Colicin E7, ZINC ION | | 著者 | Doudeva, L.G, Huang, H, Hsia, K.C, Shi, Z, Li, C.L, Shen, Y, Yuan, H.S. | | 登録日 | 2005-05-12 | | 公開日 | 2006-03-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structural analysis and metal-dependent stability and activity studies of the ColE7 endonuclease domain in complex with DNA/Zn2+ or inhibitor/Ni2+
Protein Sci., 15, 2006
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1YWX
 | | Solution Structure of Methanococcus maripaludis Protein MMP0443: The Northeast Structural Genomics Consortium Target MrR16 | | 分子名称: | 30S ribosomal protein S24e | | 著者 | Yang, C.S, Acton, T, Shen, Y, Ma, L, Liu, G, Xiao, R, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2005-02-18 | | 公開日 | 2005-04-05 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of Methanococcus maripaludis Protein MMP0443: The Northeast Structural Genomics Consortium Target MrR16
To be Published
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