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PDB: 2 results

7R3Y
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BU of 7r3y by Molmil
The crystal structure of the V426L variant of Pol2CORE in complex with DNA and an incoming nucleotide
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA Primer, ...
Authors:Barbari, S.R, Beach, A.K, Markgren, J.G, Parkash, V, Johansson, E, Shcherbakova, P.V.
Deposit date:2022-02-08
Release date:2022-07-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Enhanced polymerase activity permits efficient synthesis by cancer-associated DNA polymerase ε variants at low dNTP levels.
Nucleic Acids Res., 50, 2022
7R3X
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BU of 7r3x by Molmil
The crystal structure of the L439V variant of Pol2CORE in complex with DNA and an incoming nucleotide
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ACETATE ION, CALCIUM ION, ...
Authors:Barbari, S.R, Beach, A.K, Markgren, J.G, Parkash, V, Johansson, E, Shcherbakova, P.V.
Deposit date:2022-02-08
Release date:2022-07-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Enhanced polymerase activity permits efficient synthesis by cancer-associated DNA polymerase ε variants at low dNTP levels.
Nucleic Acids Res., 50, 2022

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