6IXI
| structure of Cd-bound periplasmic metal binding protein from candidatus liberibacter asiaticus | Descriptor: | ACETATE ION, CADMIUM ION, GLYCEROL, ... | Authors: | Kumar, P, Sharma, N, Dalal, V, Ghosh, D.K, Kumar, P, Sharma, A.K. | Deposit date: | 2018-12-10 | Release date: | 2020-01-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Characterization of the heavy metal binding properties of periplasmic metal uptake protein CLas-ZnuA2. Metallomics, 12, 2020
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3ZC8
| Crystal Structure of Murraya koenigii Miraculin-Like Protein at 2.2 A resolution at pH 7.0 | Descriptor: | TRYPSIN INHIBITOR | Authors: | Selvakumar, P, Sharma, N, Tomar, P.P.S, Kumar, P, Sharma, A.K. | Deposit date: | 2012-11-19 | Release date: | 2013-12-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structural Insights Into the Aggregation Behavior of Murraya Koenigii Miraculin-Like Protein Below Ph 7.5. Proteins, 82, 2014
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3ZC9
| Crystal Structure of Murraya koenigii Miraculin-Like Protein at 2.2 A resolution at pH 4.6 | Descriptor: | TRYPSIN INHIBITOR | Authors: | Selvakumar, P, Sharma, N, Tomar, P.P.S, Kumar, P, Sharma, A.K. | Deposit date: | 2012-11-19 | Release date: | 2013-12-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structural Insights Into the Aggregation Behavior of Murraya Koenigii Miraculin-Like Protein Below Ph 7.5. Proteins, 82, 2014
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5Z35
| Structure of Y68F mutant metal free periplasmic metal binding protein from candidatus liberibacter asiaticus | Descriptor: | ACETATE ION, GLYCEROL, Periplasmic solute binding protein, ... | Authors: | Saini, G, Sharma, N, Dalal, V, Kumar, P, Sharma, A.K. | Deposit date: | 2018-01-05 | Release date: | 2018-10-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The analysis of subtle internal communications through mutation studies in periplasmic metal uptake protein CLas-ZnuA2 J. Struct. Biol., 204, 2018
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2WZX
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5Z2K
| Structure of S38A mutant Mn-bound periplasmic metal binding protein from candidatus liberibacter asiaticus | Descriptor: | ACETATE ION, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Saini, G, Sharma, N, Dalal, V, Kumar, P, Sharma, A.K. | Deposit date: | 2018-01-02 | Release date: | 2018-10-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The analysis of subtle internal communications through mutation studies in periplasmic metal uptake protein CLas-ZnuA2 J. Struct. Biol., 204, 2018
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5Z2J
| structure of S38A mutant metal-free periplasmic metal binding protein from candidatus liberibacter asiaticus | Descriptor: | ACETATE ION, GLYCEROL, Periplasmic solute binding protein, ... | Authors: | Saini, G, Sharma, N, Dalal, V, Kumar, P, Sharma, A.K. | Deposit date: | 2018-01-02 | Release date: | 2018-10-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | The analysis of subtle internal communications through mutation studies in periplasmic metal uptake protein CLas-ZnuA2 J. Struct. Biol., 204, 2018
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5ZHA
| Structure of Y68F mutant Mn-Bound periplasmic metal binding protein from candidatus liberibacter asiaticus | Descriptor: | ACETATE ION, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Saini, G, Sharma, N, Dalal, V, Kumar, P, Sharma, A.K. | Deposit date: | 2018-03-12 | Release date: | 2018-10-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | The analysis of subtle internal communications through mutation studies in periplasmic metal uptake protein CLas-ZnuA2 J. Struct. Biol., 204, 2018
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1XP9
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1XP6
| HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 16 | Descriptor: | (2S,3R)-2-(4-{2-[(3S,4S)-3,4-DIMETHYLPYRROLIDIN-1-YL]ETHOXY}PHENYL)-3-(4-HYDROXYPHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6-OL, Estrogen receptor | Authors: | Fitzgerald, P.M.D, Sharma, N. | Deposit date: | 2004-10-08 | Release date: | 2004-12-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers. Bioorg.Med.Chem.Lett., 15, 2005
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1XP1
| HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 15 | Descriptor: | (2S,3R)-2-(4-{2-[(3R,4R)-3,4-DIMETHYLPYRROLIDIN-1-YL]ETHOXY}PHENYL)-3-(4-HYDROXYPHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6- OL, Estrogen receptor | Authors: | Fitzgerald, P.M.D, Sharma, N. | Deposit date: | 2004-10-07 | Release date: | 2004-12-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers. Bioorg.Med.Chem.Lett., 15, 2005
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1XPC
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1YIM
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1YIN
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1SJ0
| Human Estrogen Receptor Alpha Ligand-binding Domain in Complex with the Antagonist Ligand 4-D | Descriptor: | (2S,3R)-2-(4-(2-(PIPERIDIN-1-YL)ETHOXY)PHENYL)-2,3-DIHYDRO-3-(4-HYDROXYPHENYL)BENZO[B][1,4]OXATHIIN-6-OL, Estrogen receptor | Authors: | Kim, S, Wu, J.Y, Birzin, E.T, Chan, W, Pai, L.Y, Yang, Y.T, Mosley, R.T, Fitzgerald, P.M, Sharma, N, DiNinno, F, Rohrer, S.P, Schaeffer, J.M, Hammond, M.L. | Deposit date: | 2004-03-02 | Release date: | 2004-04-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Estrogen Receptor Ligands. II. Discovery of Benzoxathiins as Potent, Selective Estrogen Receptor alpha Modulators. J.Med.Chem., 47, 2004
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2GIU
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3S22
| AMP-C BETA-LACTAMASE (PSEUDOMONAS AERUGINOSA) in complex with an inhibitor | Descriptor: | Beta-lactamase, CHLORIDE ION, [(2S,3R)-2-formyl-1-{[4-(methylamino)butyl]carbamoyl}pyrrolidin-3-yl]sulfamic acid | Authors: | Scapin, G, Lu, J, Fitzgerald, P.M.D, Sharma, N. | Deposit date: | 2011-05-16 | Release date: | 2011-06-29 | Last modified: | 2013-06-26 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Side chain SAR of bicyclic Beta-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712 Bioorg.Med.Chem.Lett., 21, 2011
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3S1Y
| AMP-C BETA-LACTAMASE (PSEUDOMONAS AERUGINOSA) in complex with a beta-lactamase inhibitor | Descriptor: | Beta-lactamase, CHLORIDE ION, ISOPROPYL ALCOHOL, ... | Authors: | Scapin, G, Lu, J, Fitzgerald, P.M.D, Sharma, N. | Deposit date: | 2011-05-16 | Release date: | 2011-06-29 | Last modified: | 2013-06-26 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Side chain SAR of bicyclic Beta-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712 Bioorg.Med.Chem.Lett., 21, 2011
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4I14
| Crystal Structure of Mtb-ribA2 (Rv1415) | Descriptor: | Riboflavin biosynthesis protein RibBA, SULFATE ION, ZINC ION | Authors: | Singh, M, Kumar, P, Yadav, S, Gautam, R, Sharma, N, Karthikeyan, S. | Deposit date: | 2012-11-20 | Release date: | 2013-08-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The crystal structure reveals the molecular mechanism of bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II (Rv1415) from Mycobacterium tuberculosis Acta Crystallogr.,Sect.D, 69, 2013
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5TN9
| Crystal Structure of the ER-alpha Ligand-binding Domain (L372S,L536S) in Complex with the OBHS-BSC, 4-bromophenyl (1R,2R,4S)-5-(4-hydroxyphenyl)-6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate | Descriptor: | 4-bromophenyl (1S,2R,4S)-5-(4-hydroxyphenyl)-6-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate, Estrogen receptor | Authors: | Nwachukwu, J.C, Sharma, N, Carlson, K.E, Srinivasan, S, Sharma, A, Katzenellenbogen, J.A, Nettles, K.W. | Deposit date: | 2016-10-13 | Release date: | 2017-02-15 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.253 Å) | Cite: | Exploring the Structural Compliancy versus Specificity of the Estrogen Receptor Using Isomeric Three-Dimensional Ligands. ACS Chem. Biol., 12, 2017
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2IOG
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2IOK
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