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PDB: 11 件
1DMB
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REFINED 1.8 ANGSTROMS STRUCTURE REVEALS THE MECHANISM OF BINDING OF A CYCLIC SUGAR, BETA-CYCLODEXTRIN, TO THE MALTODEXTRIN BINDING PROTEIN
分子名称: Cycloheptakis-(1-4)-(alpha-D-glucopyranose), D-MALTODEXTRIN BINDING PROTEIN
著者Sharff, A.J, Quiocho, F.A.
登録日1993-06-10
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Refined 1.8-A structure reveals the mode of binding of beta-cyclodextrin to the maltodextrin binding protein.
Biochemistry, 32, 1993
1MDQ
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REFINED STRUCTURES OF TWO INSERTION(SLASH)DELETION MUTANTS PROBE FUNCTION OF THE MALTODEXTRIN BINDING PROTEIN
分子名称: MALTODEXTRIN BINDING PROTEIN, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Sharff, A.J, Quiocho, F.A.
登録日1994-08-10
公開日1994-11-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Refined structures of two insertion/deletion mutants probe function of the maltodextrin binding protein.
J.Mol.Biol., 246, 1995
1MDP
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BU of 1mdp by Molmil
REFINED STRUCTURES OF TWO INSERTION(SLASH)DELETION MUTANTS PROBE FUNCTION OF THE MALTODEXTRIN BINDING PROTEIN
分子名称: MALTODEXTRIN BINDING PROTEIN, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Sharff, A.J, Quiocho, F.A.
登録日1994-08-10
公開日1994-11-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Refined structures of two insertion/deletion mutants probe function of the maltodextrin binding protein.
J.Mol.Biol., 246, 1995
1OMP
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BU of 1omp by Molmil
CRYSTALLOGRAPHIC EVIDENCE OF A LARGE LIGAND-INDUCED HINGE-TWIST MOTION BETWEEN THE TWO DOMAINS OF THE MALTODEXTRIN-BINDING PROTEIN INVOLVED IN ACTIVE TRANSPORT AND CHEMOTAXIS
分子名称: D-MALTODEXTRIN BINDING PROTEIN
著者Sharff, A.J, Quiocho, F.A.
登録日1992-09-14
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystallographic evidence of a large ligand-induced hinge-twist motion between the two domains of the maltodextrin binding protein involved in active transport and chemotaxis.
Biochemistry, 31, 1992
2Q15
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BU of 2q15 by Molmil
Structure of BACE complexed to compound 3a
分子名称: (4S)-4-(2-AMINO-6-PHENOXYQUINAZOLIN-3(4H)-YL)-N,4-DICYCLOHEXYL-N-METHYLBUTANAMIDE, Beta-secretase 1
著者Sharff, A.J.
登録日2007-05-23
公開日2007-08-14
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-Site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead.
J.Med.Chem., 50, 2007
2Q11
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Structure of BACE complexed to compound 1
分子名称: 3-(2-AMINO-6-BENZOYLQUINAZOLIN-3(4H)-YL)-N-CYCLOHEXYL-N-METHYLPROPANAMIDE, Beta-secretase 1
著者Sharff, A.J.
登録日2007-05-23
公開日2007-08-14
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-Site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead.
J.Med.Chem., 50, 2007
1EK9
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BU of 1ek9 by Molmil
2.1A X-RAY STRUCTURE OF TOLC: AN INTEGRAL OUTER MEMBRANE PROTEIN AND EFFLUX PUMP COMPONENT FROM ESCHERICHIA COLI
分子名称: OUTER MEMBRANE PROTEIN TOLC
著者Koronakis, V, Sharff, A.J, Koronakis, E, Luisi, B, Hughes, C.
登録日2000-03-07
公開日2000-06-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export.
Nature, 405, 2000
6CDS
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BU of 6cds by Molmil
Human neurofibromin 2/merlin/schwannomin residues 1-339 in complex with PIP2
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Merlin, ...
著者Chinthalapudi, K, Sharff, A.J, Bricogne, G, Izard, T.
登録日2018-02-09
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2.
Nat Commun, 9, 2018
3U8Z
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human merlin FERM domain
分子名称: Merlin
著者Yogesha, S.D, Sharff, A.J, Giovannini, M, Bricogne, G, Izard, T.
登録日2011-10-17
公開日2011-11-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Unfurling of the band 4.1, ezrin, radixin, moesin (FERM) domain of the merlin tumor suppressor.
Protein Sci., 20, 2011
3P39
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Crystal structure of the NS1 effector domain W182A mutant from influenza A/Vietnam/1203/2004 (H5N1) virus
分子名称: Nonstructural protein 1
著者Chen, S, Xiao, Y.B, Bricogne, G, Sharff, A.J, Hilgenfeld, R.
登録日2010-10-04
公開日2011-10-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献X-ray structures of the NS1 effector domain from highly pathogenic influenza A/Vietnam/1203/2004 (H5N1) virus
To be Published
3P38
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Crystal structure of the NS1 effector domain W182A mutant from influenza A/Vietnam/1203/2004 (H5N1) virus
分子名称: Nonstructural protein 1
著者Chen, S, Xiao, Y.B, Bricogne, G, Sharff, A.J, Hilgenfeld, R.
登録日2010-10-04
公開日2011-10-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献X-ray structures of the NS1 effector domain from highly pathogenic influenza A/Vietnam/1203/2004 (H5N1) virus
To be Published

227111

件を2024-11-06に公開中

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