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PDB: 15 件

3ZKT
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SOLUTION STRUCTURE OF THE SOMATOSTATIN SST3 RECEPTOR ANTAGONIST TAU- CONOTOXIN CnVA
分子名称: TAU-CNVA
著者Petrel, C, Hocking, H.G, Reynaud, M, Favreau, P, Paolini-Bertrand, M, Peigneur, S, Upert, G, Tytgat, J, Gilles, N, Hartley, O, Boelens, R, Stocklin, R, Servent, D.
登録日2013-01-24
公開日2013-04-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Identification, Structural and Pharmacological Characterization of Tau-Cnva, a Conopeptide that Selectively Interacts with Somatostatin Sst3 Receptor.
Biochem.Pharmacol, 85, 2013
8AJ7
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Kunitz domain of Amblyomin-X
分子名称: 1,2-ETHANEDIOL, Kunitz domain of Amblyomin-X
著者Ciccone, L, Servent, D, Stura, E.A.
登録日2022-07-27
公開日2023-02-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and functional properties of the Kunitz-type and C-terminal domains of Amblyomin-X supporting its antitumor activity.
Front Mol Biosci, 10, 2023
1B45
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ALPHA-CNIA CONOTOXIN FROM CONUS CONSORS, NMR, 43 STRUCTURES
分子名称: ALPHA-CNIA
著者Favreau, P, Krimm, I, Le Gall, F, Bobenrieth, M.J, Lamthanh, H, Bouet, F, Servent, D, Molgo, J, Menez, A, Letourneux, Y, Lancelin, J.M.
登録日1999-01-05
公開日1999-07-09
最終更新日2024-10-09
実験手法SOLUTION NMR
主引用文献Biochemical characterization and nuclear magnetic resonance structure of novel alpha-conotoxins isolated from the venom of Conus consors.
Biochemistry, 38, 1999
1G2G
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MINIMAL CONFORMATION OF THE ALPHA-CONOTOXIN IMI FOR THE ALPHA7 NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR RECOGNITION
分子名称: ALPHA-CONOTOXIN IMI
著者Lamthanh, H, Jegou-Matheron, C, Servent, D, Menez, A, Lancelin, J.M.
登録日2000-10-19
公開日2000-11-08
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献Minimal conformation of the alpha-conotoxin ImI for the alpha7 neuronal nicotinic acetylcholine receptor recognition: correlated CD, NMR and binding studies.
FEBS Lett., 454, 1999
4DO8
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Crystal structure of the muscarinic toxin MT1
分子名称: ACETATE ION, Muscarinic toxin 1, THIOCYANATE ION
著者Fruchart-Gaillard, C, Mournier, G, Vera, L, Servent, D, Stura, E.A.
登録日2012-02-09
公開日2012-06-27
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Engineering of three-finger fold toxins creates ligands with original pharmacological profiles for muscarinic and adrenergic receptors.
Plos One, 7, 2012
3NEQ
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Crystal structure of the chimeric muscarinic toxin MT7 with loop 3 from MT1
分子名称: SULFATE ION, Three-finger muscarinic toxin 7
著者Stura, E.A, Servent, D, Menez, R, Mournier, G, Menez, A, Fruchart-Gaillard, C.
登録日2010-06-09
公開日2011-08-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Engineering of three-finger fold toxins creates ligands with original pharmacological profiles for muscarinic and adrenergic receptors.
Plos One, 7, 2012
6R5M
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Crystal structure of toxin MT9 from mamba venom
分子名称: ACETYL GROUP, Dendroaspis polylepis MT9, GLYCEROL, ...
著者Stura, E.A, Tepshi, L, Ciolek, J, Triquigneaux, M, Zoukimian, C, De Waard, M, Beroud, R, Servent, D, Gilles, N, Legrand, P, Ciccone, L.
登録日2019-03-25
公開日2020-02-12
最終更新日2022-05-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献MT9, a natural peptide from black mamba venom antagonizes the muscarinic type 2 receptor and reverses the M2R-agonist-induced relaxation in rat and human arteries
Biomed Pharmacother, 150, 2022
2LDE
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Solution structure of the long sarafotoxin srtx-i3
分子名称: Sarafotoxin-i3
著者Cordier, F, Zorba, A, Hajj, M, Ducancel, F, Servent, D, Delepierre, M.
登録日2011-05-24
公開日2011-09-21
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Pharmacological and structural characterization of long-sarafotoxins, a new family of endothelin-like peptides: Role of the C-terminus extension.
Biochimie, 94, 2012
2X00
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CRYSTAL STRUCTURE OF A-ACHBP IN COMPLEX WITH GYMNODIMINE A
分子名称: GYMNODIMINE A, SOLUBLE ACETYLCHOLINE RECEPTOR
著者Bourne, Y, Radic, Z, Araoz, R, Talley, T.T, Benoit, E, Servent, D, Taylor, P, Molgo, J, Marchot, P.
登録日2009-12-04
公開日2010-03-02
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Determinants in Phycotoxins and Achbp Conferring High Affinity Binding and Nicotinic Achr Antagonism.
Proc.Natl.Acad.Sci.USA, 107, 2010
2LDF
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Solution structure of the long sarafotoxin srtx-m
分子名称: Sarafotoxin-m
著者Cordier, F, Zorba, A, Hajj, M, Ducancel, F, Servent, D, Delepierre, M.
登録日2011-05-24
公開日2011-09-21
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Pharmacological and structural characterization of long-sarafotoxins, a new family of endothelin-like peptides: Role of the C-terminus extension.
Biochimie, 94, 2012
5MG9
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Putative Ancestral Mamba toxin 1 (AncTx1-W28R/I38S)
分子名称: 1,2-ETHANEDIOL, AncTx1-W28R/I38S, S-1,2-PROPANEDIOL, ...
著者Stura, E.A, Tepshi, L, Blanchet, G, Mourier, G, Servent, D.
登録日2016-11-21
公開日2017-05-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Ancestral protein resurrection and engineering opportunities of the mamba aminergic toxins.
Sci Rep, 7, 2017
2WZY
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Crystal structure of A-AChBP in complex with 13-desmethyl spirolide C
分子名称: 13-DESMETHYL SPIROLIDE C, SOLUBLE ACETYLCHOLINE RECEPTOR
著者Bourne, Y, Radic, Z, Araoz, R, Talley, T.T, Benoit, E, Servent, D, Taylor, P, Molgo, J, Marchot, P.
登録日2009-12-03
公開日2010-03-02
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural Determinants in Phycotoxins and Achbp Conferring High Affinity Binding and Nicotinic Achr Antagonism.
Proc.Natl.Acad.Sci.USA, 107, 2010
5DU1
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Crystal structure of Dendroaspis polylepis mambalgin-1 wild-type in P21 space group.
分子名称: Mambalgin-1
著者Stura, E.A, Tepshi, L, Mourier, G, Kessler, P, Servent, D.
登録日2015-09-18
公開日2015-12-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition.
J.Biol.Chem., 291, 2016
5DO6
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Crystal structure of Dendroaspis polylepis venom mambalgin-1 T23A mutant
分子名称: 1,2-ETHANEDIOL, IODIDE ION, Mambalgin-1, ...
著者Stura, E.A, Tepshi, L, Kessler, P, Gilles, M, Servent, D.
登録日2015-09-10
公開日2015-12-30
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.697 Å)
主引用文献Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition.
J.Biol.Chem., 291, 2016
5DZ5
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Crystal structure of Dendroaspis polylepis mambalgin-1 wild-type in P41212 space group
分子名称: Mambalgin-1
著者Stura, E.A, Tepshi, L, Mourier, G, Kessler, P, Servent, D.
登録日2015-09-25
公開日2015-12-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition.
J.Biol.Chem., 291, 2016

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