6WO0
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![BU of 6wo0 by Molmil](/molmil-images/mine/6wo0) | human Artemis/SNM1C catalytic domain, crystal form 1 | 分子名称: | GLYCEROL, Protein artemis, ZINC ION | 著者 | Karim, F, Liu, S, Laciak, A.R, Volk, L, Rosenblum, M, Curtis, R, Huang, N, Carr, G, Zhu, G. | 登録日 | 2020-04-23 | 公開日 | 2020-07-01 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Structural analysis of the catalytic domain of Artemis endonuclease/SNM1C reveals distinct structural features. J.Biol.Chem., 295, 2020
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6WNL
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![BU of 6wnl by Molmil](/molmil-images/mine/6wnl) | human Artemis/SNM1C catalytic domain, crystal form 2 | 分子名称: | Protein artemis, ZINC ION | 著者 | Karim, F, Liu, S, Laciak, A.R, Volk, L, Rosenblum, M, Curtis, R, Huang, N, Carr, G, Zhu, G. | 登録日 | 2020-04-22 | 公開日 | 2020-07-01 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Structural analysis of the catalytic domain of Artemis endonuclease/SNM1C reveals distinct structural features. J.Biol.Chem., 295, 2020
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7OE7
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![BU of 7oe7 by Molmil](/molmil-images/mine/7oe7) | Apo-structure of Lassa virus L protein (well-resolved alpha ribbon) [APO-RIBBON] | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | 登録日 | 2021-05-01 | 公開日 | 2021-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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7OJK
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![BU of 7ojk by Molmil](/molmil-images/mine/7ojk) | Lassa virus L protein bound to the distal promoter duplex [DISTAL-PROMOTER] | 分子名称: | 3' RNA, 5' RNA, RNA-directed RNA polymerase L, ... | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | 登録日 | 2021-05-16 | 公開日 | 2021-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.89 Å) | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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7OEA
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![BU of 7oea by Molmil](/molmil-images/mine/7oea) | Lassa virus L protein bound to 3' promoter RNA (well-resolved polymerase core) [3END-CORE] | 分子名称: | 3' vRNA, MAGNESIUM ION, RNA-directed RNA polymerase L, ... | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | 登録日 | 2021-05-02 | 公開日 | 2021-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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7OCH
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![BU of 7och by Molmil](/molmil-images/mine/7och) | Apo-structure of Lassa virus L protein (well-resolved polymerase core) [APO-CORE] | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | 登録日 | 2021-04-26 | 公開日 | 2021-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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7OJN
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![BU of 7ojn by Molmil](/molmil-images/mine/7ojn) | Lassa virus L protein in an elongation conformation [ELONGATION] | 分子名称: | 3' RNA, 5' RNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | 登録日 | 2021-05-16 | 公開日 | 2021-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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7OE3
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![BU of 7oe3 by Molmil](/molmil-images/mine/7oe3) | Apo-structure of Lassa virus L protein (well-resolved endonuclease) [APO-ENDO] | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | 登録日 | 2021-05-01 | 公開日 | 2021-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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7OEB
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![BU of 7oeb by Molmil](/molmil-images/mine/7oeb) | Lassa virus L protein bound to 3' promoter RNA (well-resolved endonuclease) [3END-ENDO] | 分子名称: | 3' vRNA, MAGNESIUM ION, RNA-directed RNA polymerase L, ... | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | 登録日 | 2021-05-02 | 公開日 | 2021-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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7OJJ
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![BU of 7ojj by Molmil](/molmil-images/mine/7ojj) | Lassa virus L protein with endonuclease and C-terminal domains in close proximity [MID-LINK] | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | 登録日 | 2021-05-16 | 公開日 | 2021-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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7OJL
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![BU of 7ojl by Molmil](/molmil-images/mine/7ojl) | Lassa virus L protein in a pre-initiation conformation [PREINITIATION] | 分子名称: | 3' RNA, 5' RNA, MANGANESE (II) ION, ... | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | 登録日 | 2021-05-16 | 公開日 | 2021-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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6ISV
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![BU of 6isv by Molmil](/molmil-images/mine/6isv) | Structure of acetophenone reductase from Geotrichum candidum NBRC 4597 in complex with NAD | 分子名称: | Acetophenone reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION | 著者 | Koesoema, A.A, Sugiyama, Y, Senda, M, Senda, T, Matsuda, T. | 登録日 | 2018-11-19 | 公開日 | 2019-09-11 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for a highly (S)-enantioselective reductase towards aliphatic ketones with only one carbon difference between side chain. Appl.Microbiol.Biotechnol., 103, 2019
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8PXV
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![BU of 8pxv by Molmil](/molmil-images/mine/8pxv) | Targeting extended blood antigens by Akkermansia muciniphila enzymes unveils a missing link for generating universal donor blood | 分子名称: | Beta-N-acetylhexosaminidase, GLYCEROL, SODIUM ION, ... | 著者 | Weikum, J, Jensen, M, Abou Hachem, M, Morth, J.P. | 登録日 | 2023-07-24 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Akkermansia muciniphila exoglycosidases target extended blood group antigens to generate ABO-universal blood. Nat Microbiol, 9, 2024
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8OXA
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![BU of 8oxa by Molmil](/molmil-images/mine/8oxa) | Cryo-EM structure of ATP8B1-CDC50A in E2-Pi conformation with occluded PS | 分子名称: | (2~{S})-2-azanyl-3-[[(2~{R})-3-hexadecanoyloxy-2-[(~{Z})-octadec-9-enoyl]oxy-propoxy]-oxidanyl-phosphoryl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell cycle control protein 50A, ... | 著者 | Dieudonne, T, Kummerer, F, Juknaviciute Laursen, M, Stock, C, Kock Flygaard, R, Khalid, S, Lenoir, G, Lyons, J.A, Lindorff-Larsen, K, Nissen, P. | 登録日 | 2023-05-01 | 公開日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Activation and substrate specificity of the human P4-ATPase ATP8B1. Nat Commun, 14, 2023
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8OX7
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![BU of 8ox7 by Molmil](/molmil-images/mine/8ox7) | Cryo-EM structure of ATP8B1-CDC50A in E2P autoinhibited "closed" conformation | 分子名称: | (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell cycle control protein 50A, ... | 著者 | Dieudonne, T, Kummerer, F, Juknaviciute Laursen, M, Stock, C, Kock Flygaard, R, Khalid, S, Lenoir, G, Lyons, J.A, Lindorff-Larsen, K, Nissen, P. | 登録日 | 2023-05-01 | 公開日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | 主引用文献 | Activation and substrate specificity of the human P4-ATPase ATP8B1. Nat Commun, 14, 2023
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8OX6
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![BU of 8ox6 by Molmil](/molmil-images/mine/8ox6) | Cryo-EM structure of ATP8B1-CDC50A in E1P conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell cycle control protein 50A, MAGNESIUM ION, ... | 著者 | Dieudonne, T, Kummerer, F, Juknaviciute Laursen, M, Stock, C, Kock Flygaard, R, Khalid, S, Lenoir, G, Lyons, J.A, Lindorff-Larsen, K, Nissen, P. | 登録日 | 2023-05-01 | 公開日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (2.39 Å) | 主引用文献 | Activation and substrate specificity of the human P4-ATPase ATP8B1. Nat Commun, 14, 2023
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8OX8
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![BU of 8ox8 by Molmil](/molmil-images/mine/8ox8) | Cryo-EM structure of ATP8B1-CDC50A in E2P autoinhibited "open" conformation | 分子名称: | (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell cycle control protein 50A, ... | 著者 | Dieudonne, T, Kummerer, F, Juknaviciute Laursen, M, Stock, C, Kock Flygaard, R, Khalid, S, Lenoir, G, Lyons, J.A, Lindorff-Larsen, K, Nissen, P. | 登録日 | 2023-05-01 | 公開日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Activation and substrate specificity of the human P4-ATPase ATP8B1. Nat Commun, 14, 2023
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8OXB
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![BU of 8oxb by Molmil](/molmil-images/mine/8oxb) | Cryo-EM structure of ATP8B1-CDC50A in E2-Pi conformation with occluded PC | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell cycle control protein 50A, ... | 著者 | Dieudonne, T, Kummerer, F, Juknaviciute Laursen, M, Stock, C, Kock Flygaard, R, Khalid, S, Lenoir, G, Lyons, J.A, Lindorff-Larsen, K, Nissen, P. | 登録日 | 2023-05-01 | 公開日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | 主引用文献 | Activation and substrate specificity of the human P4-ATPase ATP8B1. Nat Commun, 14, 2023
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8OX5
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![BU of 8ox5 by Molmil](/molmil-images/mine/8ox5) | Cryo-EM structure of ATP8B1-CDC50A in E1P-ADP conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Cell cycle control protein 50A, ... | 著者 | Dieudonne, T, Kummerer, F, Juknaviciute Laursen, M, Stock, C, Kock Flygaard, R, Khalid, S, Lenoir, G, Lyons, J.A, Lindorff-Larsen, K, Nissen, P. | 登録日 | 2023-05-01 | 公開日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Activation and substrate specificity of the human P4-ATPase ATP8B1. Nat Commun, 14, 2023
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8OXC
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![BU of 8oxc by Molmil](/molmil-images/mine/8oxc) | Cryo-EM structure of ATP8B1-CDC50A in E2-Pi conformation with occluded PI | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell cycle control protein 50A, ... | 著者 | Dieudonne, T, Kummerer, F, Juknaviciute Laursen, M, Stock, C, Kock Flygaard, R, Khalid, S, Lenoir, G, Lyons, J.A, Lindorff-Larsen, K, Nissen, P. | 登録日 | 2023-05-01 | 公開日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | 主引用文献 | Activation and substrate specificity of the human P4-ATPase ATP8B1. Nat Commun, 14, 2023
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8OX4
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![BU of 8ox4 by Molmil](/molmil-images/mine/8ox4) | Cryo-EM structure of ATP8B1-CDC50A in E1-ATP conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell cycle control protein 50A, MAGNESIUM ION, ... | 著者 | Dieudonne, T, Kummerer, F, Juknaviciute Laursen, M, Stock, C, Kock Flygaard, R, Khalid, S, Lenoir, G, Lyons, J.A, Lindorff-Larsen, K, Nissen, P. | 登録日 | 2023-05-01 | 公開日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Activation and substrate specificity of the human P4-ATPase ATP8B1. Nat Commun, 14, 2023
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8OX9
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![BU of 8ox9 by Molmil](/molmil-images/mine/8ox9) | Cryo-EM structure of ATP8B1-CDC50A in E2P active conformation with bound PC | 分子名称: | (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Dieudonne, T, Kummerer, F, Juknaviciute Laursen, M, Stock, C, Kock Flygaard, R, Khalid, S, Lenoir, G, Lyons, J.A, Lindorff-Larsen, K, Nissen, P. | 登録日 | 2023-05-01 | 公開日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | 主引用文献 | Activation and substrate specificity of the human P4-ATPase ATP8B1. Nat Commun, 14, 2023
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6Q88
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![BU of 6q88 by Molmil](/molmil-images/mine/6q88) | RT structure of HEWL at 5 kGy | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Lysozyme C | 著者 | de la Mora, E, Coquelle, N, Bury, C.S, Rosenthal, M, Garman, E.F, Burghammer, M, Colletier, J.P, Weik, M. | 登録日 | 2018-12-14 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.74007058 Å) | 主引用文献 | Radiation damage and dose limits in serial synchrotron crystallography at cryo- and room temperatures. Proc.Natl.Acad.Sci.USA, 117, 2020
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6Q8T
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![BU of 6q8t by Molmil](/molmil-images/mine/6q8t) | Cryo structure of HEWL at 81 kGy | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Lysozyme C | 著者 | de la Mora, E, Coquelle, N, Bury, C.S, Rosenthal, M, Garman, E.F, Burghammer, M, Colletier, J.P, Weik, M. | 登録日 | 2018-12-16 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.74008667 Å) | 主引用文献 | Radiation damage and dose limits in serial synchrotron crystallography at cryo- and room temperatures. Proc.Natl.Acad.Sci.USA, 117, 2020
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6XYA
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![BU of 6xya by Molmil](/molmil-images/mine/6xya) | Cap-binding domain of SFTSV L protein | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, RNA-dependent RNA polymerase, SODIUM ION | 著者 | Gogrefe, N, Guenther, S, Rosenthal, M. | 登録日 | 2020-01-30 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structural and functional characterization of the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res., 48, 2020
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