6ERA
 
 | |
4H1S
 | | Crystal Structure of a Truncated Soluble form of Human CD73 with Ecto-5'-Nucleotidase activity | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-nucleotidase, PHOSPHATE ION, ... | | 著者 | Heuts, D.P, Weissenborn, M.J, Olkhov, R.V, Shaw, A.M, Levy, C.W, Scrutton, N.S. | | 登録日 | 2012-09-11 | | 公開日 | 2012-10-03 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of a soluble form of human CD73 with ecto-5'-nucleotidase activity.
Chembiochem, 13, 2012
|
|
5NX6
 | | Crystal structure of 1,8-cineole synthase from Streptomyces clavuligerus in complex with 2-fluoroneryl diphosphate | | 分子名称: | (2E)-2-fluoro-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate, 2-ethyl-2-(hydroxymethyl)propane-1,3-diol, ETHYL DIMETHYL AMMONIO PROPANE SULFONATE, ... | | 著者 | Karuppiah, V, Leys, D, Scrutton, N.S. | | 登録日 | 2017-05-09 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase.
ACS Catal, 7, 2017
|
|
5NX5
 | | Crystal structure of Linalool/Nerolidol synthase from Streptomyces clavuligerus in complex with 2-fluorogeranyl diphosphate | | 分子名称: | (2Z)-2-fluoro-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate, CHLORIDE ION, GLYCEROL, ... | | 著者 | Karuppiah, V, Leys, D, Scrutton, N.S. | | 登録日 | 2017-05-09 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase.
ACS Catal, 7, 2017
|
|
1DJN
 | | STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF RECOMBINANT WILD TYPE TRIMETHYLAMINE DEHYDROGENASE FROM METHYLOPHILUS METHYLOTROPHUS (SP. W3A1) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... | | 著者 | Trickey, P, Basran, J, Lian, L.-Y, Chen, Z.-W, Barton, J.D, Sutcliffe, M.J, Scrutton, N.S, Mathews, F.S. | | 登録日 | 1999-12-03 | | 公開日 | 1999-12-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural and biochemical characterization of recombinant wild type and a C30A mutant of trimethylamine dehydrogenase from methylophilus methylotrophus (sp. W(3)A(1)).
Biochemistry, 39, 2000
|
|
1DJQ
 | | STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF RECOMBINANT C30A MUTANT OF TRIMETHYLAMINE DEHYDROGENASE FROM METHYLOPHILUS METHYLOTROPHUS (SP. W3A1) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... | | 著者 | Trickey, P, Basran, J, Lian, L.-Y, Chen, Z.-W, Barton, J.D, Sutcliffe, M.J, Scrutton, N.S, Mathews, F.S. | | 登録日 | 1999-12-03 | | 公開日 | 1999-12-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural and biochemical characterization of recombinant wild type and a C30A mutant of trimethylamine dehydrogenase from methylophilus methylotrophus (sp. W(3)A(1)).
Biochemistry, 39, 2000
|
|
4CSP
 | | Structure of the F306C mutant of nitrite reductase from Achromobacter xylosoxidans | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COPPER (II) ION, DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE, ... | | 著者 | Leferink, N.G.H, Antonyuk, S.V, Houwman, J.A, Scrutton, N.S, REady, R, Hasnain, S.S. | | 登録日 | 2014-03-09 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Impact of Residues Remote from the Catalytic Centre on Enzyme Catalysis of Copper Nitrite Reductase.
Nat.Commun., 5, 2014
|
|
4CSZ
 | | STRUCTURE OF F306C MUTANT OF NITRITE REDUCTASE FROM Achromobacter XYLOSOXIDANS WITH NITRITE BOUND | | 分子名称: | COPPER (II) ION, DI(HYDROXYETHYL)ETHER, DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE, ... | | 著者 | Leferink, N.G.H, Antonyuk, S.V, Houwman, J.A, Scrutton, N.S, REady, R, Hasnain, S.S. | | 登録日 | 2014-03-11 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Impact of Residues Remote from the Catalytic Centre on Enzyme Catalysis of Copper Nitrite Reductase.
Nat.Commun., 5, 2014
|
|
4KVQ
 | | Crystal Structure of Prochlorococcus marinus aldehyde-deformylating oxygenase wild type with palmitic acid bound | | 分子名称: | Aldehyde decarbonylase, FE (III) ION, PALMITIC ACID | | 著者 | Levy, C.W, Khara, B, Menon, N, Mansell, D, Das, D, Marsh, E.N.G, Leys, D, Scrutton, N.S. | | 登録日 | 2013-05-23 | | 公開日 | 2013-06-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.842 Å) | | 主引用文献 | Production of propane and other short-chain alkanes by structure-based engineering of ligand specificity in aldehyde-deformylating oxygenase.
Chembiochem, 14, 2013
|
|
3GSI
 | | Crystal structure of D552A dimethylglycine oxidase mutant of Arthrobacter globiformis in complex with tetrahydrofolate | | 分子名称: | (6S)-5,6,7,8-TETRAHYDROFOLATE, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ... | | 著者 | Tralau, T, Lafite, P, Levy, C, Combe, J.P, Scrutton, N.S, Leys, D. | | 登録日 | 2009-03-27 | | 公開日 | 2009-04-14 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | An internal reaction chamber in dimethylglycine oxidase provides efficient protection from exposure to toxic formaldehyde.
J.Biol.Chem., 284, 2009
|
|
3GX9
 | | Structure of morphinone reductase N189A mutant in complex with tetrahydroNAD | | 分子名称: | 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FLAVIN MONONUCLEOTIDE, Morphinone reductase | | 著者 | Lafite, P, Scrutton, N.S, Leys, D. | | 登録日 | 2009-04-02 | | 公開日 | 2009-05-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Parallel Pathways and Free-Energy Landscapes for Enzymatic Hydride Transfer Probed by Hydrostatic Pressure
Chembiochem, 10, 2009
|
|
2AGL
 | | Crystal structure of the phenylhydrazine adduct of aromatic amine dehydrogenase from Alcaligenes faecalis | | 分子名称: | 1-PHENYLHYDRAZINE, Aromatic amine dehydrogenase | | 著者 | Masgrau, L, Roujeinikova, A, Johannissen, L.O, Hothi, P, Basran, J, Ranaghan, K.E, Mulholland, A.J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. | | 登録日 | 2005-07-27 | | 公開日 | 2006-04-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Atomic description of an enzyme reaction dominated by proton tunneling
Science, 312, 2006
|
|
2AGY
 | | Crystal structure of the Schiff base intermediate in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with tryptamine. Monoclinic form | | 分子名称: | 2-(1H-INDOL-3-YL)ETHANIMINE, Aromatic amine dehydrogenase | | 著者 | Masgrau, L, Roujeinikova, A, Johannissen, L.O, Hothi, P, Basran, J, Ranaghan, K.E, Mulholland, A.J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. | | 登録日 | 2005-07-27 | | 公開日 | 2006-04-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Atomic description of an enzyme reaction dominated by proton tunneling
Science, 312, 2006
|
|
2AGX
 | | Crystal structure of the Schiff base intermediate in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with tryptamine. P212121 form | | 分子名称: | 2-(1H-INDOL-3-YL)ETHANIMINE, Aromatic amine dehydrogenase | | 著者 | Masgrau, L, Roujeinikova, A, Johannissen, L.O, Hothi, P, Basran, J, Ranaghan, K.E, Mulholland, A.J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. | | 登録日 | 2005-07-27 | | 公開日 | 2006-04-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Atomic description of an enzyme reaction dominated by proton tunneling
Science, 312, 2006
|
|
2AGW
 | | Crystal structure of tryptamine-reduced aromatic amine dehydrogenase (AADH) from Alcaligenes faecalis in complex with tryptamine | | 分子名称: | 2-(1H-INDOL-3-YL)ETHANAMINE, Aromatic amine dehydrogenase | | 著者 | Masgrau, L, Roujeinikova, A, Johannissen, L.O, Hothi, P, Basran, J, Ranaghan, K.E, Mulholland, A.J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. | | 登録日 | 2005-07-27 | | 公開日 | 2006-04-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Atomic description of an enzyme reaction dominated by proton tunneling
Science, 312, 2006
|
|
2AH0
 | | Crystal structure of the carbinolamine intermediate in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with tryptamine. Monoclinic form | | 分子名称: | (1S)-1-AMINO-2-(1H-INDOL-3-YL)ETHANOL, 2-(1H-INDOL-3-YL)ETHANIMINE, Aromatic amine dehydrogenase | | 著者 | Masgrau, L, Roujeinikova, A, Johannissen, L.O, Hothi, P, Basran, J, Ranaghan, K.E, Mulholland, A.J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. | | 登録日 | 2005-07-27 | | 公開日 | 2006-04-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Atomic description of an enzyme reaction dominated by proton tunneling
Science, 312, 2006
|
|
5C5U
 | | The crystal structure of viral collagen prolyl hydroxylase vCPH from Paramecium Bursaria Chlorella virus-1 - Truncated Construct | | 分子名称: | ACETATE ION, MANGANESE (II) ION, Prolyl 4-hydroxylase, ... | | 著者 | Longbotham, J.E, Levy, C.W, Johannisen, L.O, Tarhonskaya, H, Jiang, S, Loenarz, C, Flashman, E, Hay, S, Schofiled, C.J, Scrutton, N.S. | | 登録日 | 2015-06-22 | | 公開日 | 2015-09-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure and Mechanism of a Viral Collagen Prolyl Hydroxylase.
Biochemistry, 54, 2015
|
|
5CPL
 | | The crystal structure of Xenobiotic reductase A (XenA) from Pseudomonas putida in complex with a nicotinamide mimic (mNH2) | | 分子名称: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, 1-benzyl-1,4,5,6-tetrahydropyridine-3-carboxamide, CALCIUM ION, ... | | 著者 | Knaus, T, Paul, C.E, Levy, C.W, Mutti, F.G, Hollmann, F, Scrutton, N.S. | | 登録日 | 2015-07-21 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Better than Nature: Nicotinamide Biomimetics That Outperform Natural Coenzymes.
J.Am.Chem.Soc., 138, 2016
|
|
5CPN
 | | Crystal structure of XenA from Pseudomonas putida in complex with an NADH mimic (mAc) | | 分子名称: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, 1-[(3S)-1-benzylpiperidin-3-yl]ethanone, Xenobiotic reductase | | 著者 | Knaus, T, Paul, C.E, Levy, C.W, Mutti, F.G, Hollmann, F, Scrutton, N.S. | | 登録日 | 2015-07-21 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Better than Nature: Nicotinamide Biomimetics That Outperform Natural Coenzymes.
J.Am.Chem.Soc., 138, 2016
|
|
5CPM
 | | XenA from Pseudomonas putida in complex with NADPH4. | | 分子名称: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Xenobiotic reductase | | 著者 | Knaus, T, Paul, C.E, Levy, C.W, Mutti, F.G, Hollmann, F, Scrutton, N.S. | | 登録日 | 2015-07-21 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Better than Nature: Nicotinamide Biomimetics That Outperform Natural Coenzymes.
J.Am.Chem.Soc., 138, 2016
|
|
1T9G
 | | Structure of the human MCAD:ETF complex | | 分子名称: | ADENOSINE MONOPHOSPHATE, Acyl-CoA dehydrogenase, medium-chain specific, ... | | 著者 | Toogood, H.S, van Thiel, A, Basran, J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. | | 登録日 | 2004-05-17 | | 公開日 | 2004-06-08 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Extensive domain motion and electron transfer in the human electron transferring flavoprotein-medium chain Acyl-CoA dehydrogenase complex
J.Biol.Chem., 279, 2004
|
|
1S24
 | | Rubredoxin domain II from Pseudomonas oleovorans | | 分子名称: | CADMIUM ION, Rubredoxin 2 | | 著者 | Perry, A, Tambyrajah, W, Grossmann, J.G, Lian, L.Y, Scrutton, N.S. | | 登録日 | 2004-01-08 | | 公開日 | 2004-05-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the two-iron rubredoxin of Pseudomonas oleovorans determined by NMR spectroscopy and solution X-ray scattering and interactions with rubredoxin reductase.
Biochemistry, 43, 2004
|
|
2A1U
 | | Crystal structure of the human ETF E165betaA mutant | | 分子名称: | ADENOSINE MONOPHOSPHATE, Electron transfer flavoprotein alpha-subunit, mitochondrial precursor, ... | | 著者 | Toogood, H.S, Van Thiel, A, Scrutton, N.S, Leys, D. | | 登録日 | 2005-06-21 | | 公開日 | 2005-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Stabilization of Non-productive Conformations Underpins Rapid Electron Transfer to Electron-transferring Flavoprotein
J.Biol.Chem., 280, 2005
|
|
2ABA
 | | Structure of reduced PETN reductase in complex with progesterone | | 分子名称: | FLAVIN MONONUCLEOTIDE, ISOPROPYL ALCOHOL, PROGESTERONE, ... | | 著者 | Khan, H, Barna, T, Bruce, N.C, Munro, A.W, Leys, D, Scrutton, N.S. | | 登録日 | 2005-07-15 | | 公開日 | 2005-10-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Proton transfer in the oxidative half-reaction of pentaerythritol tetranitrate reductase
Febs J., 272, 2005
|
|
2ABB
 | | Structure of PETN reductase Y186F in complex with cyanide | | 分子名称: | FLAVIN MONONUCLEOTIDE, ISOPROPYL ALCOHOL, THIOCYANATE ION, ... | | 著者 | Khan, H, Barna, T, Bruce, N.C, Munro, A.W, Leys, D, Scrutton, N.S. | | 登録日 | 2005-07-15 | | 公開日 | 2005-10-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Proton transfer in the oxidative half-reaction of pentaerythritol tetranitrate reductase
Febs J., 272, 2005
|
|
