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PDB: 100 件

5L51
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Menthone neomenthol reductase from Mentha piperita
分子名称: (-)-menthone:(+)-neomenthol reductase
著者Karuppiah, V, Toogood, H.S, Leys, D, Scrutton, N.S.
登録日2016-05-27
公開日2016-08-31
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases.
Angew.Chem.Int.Ed.Engl., 55, 2016
2O2K
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Crystal Structure of the Activation Domain of Human Methionine Synthase Isoform/Mutant D963E/K1071N
分子名称: Methionine synthase
著者Wolthers, K.R, Toogood, H.S, Jowitt, T.A, Marshall, K.R, Leys, D, Scrutton, N.S.
登録日2006-11-30
公開日2006-12-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure and solution characterization of the activation domain of human methionine synthase
Febs J., 274, 2007
2QTL
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Crystal Structure of the FAD-containing FNR-like Module of Human Methionine Synthase Reductase
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Methionine synthase reductase
著者Wolthers, K.R, Lou, X, Toogood, H.S, Leys, D, Scrutton, N.S.
登録日2007-08-02
公開日2007-11-13
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanism of Coenzyme Binding to Human Methionine Synthase Reductase Revealed through the Crystal Structure of the FNR-like Module and Isothermal Titration Calorimetry
Biochemistry, 46, 2007
2QTZ
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Crystal Structure of the NADP+-bound FAD-containing FNR-like Module of Human Methionine Synthase Reductase
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Methionine synthase reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Wolthers, K.R, Lou, X, Toogood, H.S, Leys, D, Scrutton, N.S.
登録日2007-08-02
公開日2007-11-13
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanism of Coenzyme Binding to Human Methionine Synthase Reductase Revealed through the Crystal Structure of the FNR-like Module and Isothermal Titration Calorimetry
Biochemistry, 46, 2007
2R14
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Structure of morphinone reductase in complex with tetrahydroNAD
分子名称: 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FLAVIN MONONUCLEOTIDE, Morphinone reductase
著者Costello, C.L, Scrutton, N.S, Leys, D.
登録日2007-08-22
公開日2008-07-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Mutagenesis of morphinone reductase induces multiple reactive configurations and identifies potential ambiguity in kinetic analysis of enzyme tunneling mechanisms.
J.Am.Chem.Soc., 129, 2007
2XX1
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STRUCTURE OF THE N90S MUTANT OF NITRITE REDUCTASE FROM ALCALIGENES XYLOSOXIDANS complexed with nitrite
分子名称: COPPER (II) ION, DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE, NITRITE ION, ...
著者Antonyuk, S.V, Leferink, N.G.H, Han, C, Heyes, D.J, Rigby, S.E.J, Hough, M.A, Eady, R.R, Scrutton, N.S, Hasnain, S.S.
登録日2010-11-07
公開日2011-05-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Proton-Coupled Electron Transfer in the Catalytic Cycle of Alcaligenes Xylosoxidans Copper-Dependent Nitrite Reductase.
Biochemistry, 50, 2011
2XX0
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STRUCTURE OF THE N90S-H254F MUTANT OF NITRITE REDUCTASE FROM ALCALIGENES XYLOSOXIDANS
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COPPER (II) ION, DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE, ...
著者Antonyuk, S.V, Leferink, N.G.H, Han, C, Heyes, D.J, Rigby, S.E.J, Hough, M.A, Eady, R.R, Scrutton, N.S, Hasnain, S.S.
登録日2010-11-07
公開日2011-05-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Proton-Coupled Electron Transfer in the Catalytic Cycle of Alcaligenes Xylosoxidans Copper-Dependent Nitrite Reductase.
Biochemistry, 50, 2011
2XWZ
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BU of 2xwz by Molmil
STRUCTURE OF THE RECOMBINANT NATIVE NITRITE REDUCTASE FROM ALCALIGENES XYLOSOXIDANS complexed with nitrite
分子名称: ACETATE ION, COPPER (II) ION, DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE, ...
著者Antonyuk, S.V, Leferink, N.G.H, Han, C, Heyes, D.J, Rigby, S.E.J, Hough, M.A, Eady, R.R, Scrutton, N.S, Hasnain, S.S.
登録日2010-11-06
公開日2011-05-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Proton-Coupled Electron Transfer in the Catalytic Cycle of Alcaligenes Xylosoxidans Copper-Dependent Nitrite Reductase.
Biochemistry, 50, 2011
6ER9
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BU of 6er9 by Molmil
Crystal structure of cyclohexanone monooxygenase from Rhodococcus sp. Phi1 bound to NADP+
分子名称: Cyclohexanone monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Karuppiah, V, Scrutton, N.S.
登録日2017-10-17
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Biocatalytic Routes to Lactone Monomers for Polymer Production.
Biochemistry, 57, 2018
3P62
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Wild-type pentaerythritol tetranitrate reductase containing a C-terminal 8-histidine tag
分子名称: ACETATE ION, FLAVIN MONONUCLEOTIDE, Pentaerythritol tetranitrate reductase
著者Toogood, H.S, Hulley, M.E, Scrutton, N.S.
登録日2010-10-11
公開日2010-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Focused Directed Evolution of Pentaerythritol Tetranitrate Reductase by Using Automated Anaerobic Kinetic Screening of Site-Saturated Libraries
Chembiochem, 11, 2010
3P80
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Pentaerythritol tetranitrate reductase co-crystal structure containing bound (E)-1-(3'-hydroxyphenyl)-2-nitroethene
分子名称: 3-[(E)-2-nitroethenyl]phenol, FLAVIN MONONUCLEOTIDE, Pentaerythritol tetranitrate reductase
著者Toogood, H.S, Scrutton, N.S.
登録日2010-10-13
公開日2011-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献A Site-Saturated Mutagenesis Study of Pentaerythritol Tetranitrate Reductase Reveals that Residues 181 and 184 Influence Ligand Binding, Stereochemistry and Reactivity.
Chembiochem, 12, 2011
3P8I
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Y351F mutant of pentaerythritol tetranitrate reductase containing a bound acetate molecule
分子名称: ACETATE ION, FLAVIN MONONUCLEOTIDE, Pentaerythritol tetranitrate reductase
著者Toogood, H.S, Scrutton, N.S.
登録日2010-10-14
公開日2011-04-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Active site modifications in pentaerythritol tetranitrate reductase can lead to improved product enantiopurity, decreased by-product formation and altered stereochemical outcome in reactions with a,b-unsaturated nitroolefins
Catalysis Science and Technology, 2011
3P82
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H184N mutant of pentaerythritol tetranitrate reductase containing bound acetate ion
分子名称: ACETATE ION, FLAVIN MONONUCLEOTIDE, Pentaerythritol tetranitrate reductase
著者Toogood, H.S, Scrutton, N.S.
登録日2010-10-13
公開日2011-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A Site-Saturated Mutagenesis Study of Pentaerythritol Tetranitrate Reductase Reveals that Residues 181 and 184 Influence Ligand Binding, Stereochemistry and Reactivity.
Chembiochem, 12, 2011
3P7Y
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BU of 3p7y by Molmil
Pentaerythritol tetranitrate reductase co-crystal structure with bound (E)-1-(2'-hydroxyphenyl)-2-nitroethene
分子名称: 2-[(E)-2-nitroethenyl]phenol, FLAVIN MONONUCLEOTIDE, Pentaerythritol tetranitrate reductase
著者Toogood, H.S, Scrutton, N.S.
登録日2010-10-13
公開日2011-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献A Site-Saturated Mutagenesis Study of Pentaerythritol Tetranitrate Reductase Reveals that Residues 181 and 184 Influence Ligand Binding, Stereochemistry and Reactivity.
Chembiochem, 12, 2011
3P81
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Pentaerythritol tetranitrate reductase co-crystal structure containing a bound (E)-1-(4'-hydroxyphenyl)-2-nitroethene molecule
分子名称: 4-[(E)-2-nitroethenyl]phenol, FLAVIN MONONUCLEOTIDE, Pentaerythritol tetranitrate reductase
著者Toogood, H.S, Scrutton, N.S.
登録日2010-10-13
公開日2011-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献A Site-Saturated Mutagenesis Study of Pentaerythritol Tetranitrate Reductase Reveals that Residues 181 and 184 Influence Ligand Binding, Stereochemistry and Reactivity.
Chembiochem, 12, 2011
3P67
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T26S mutant of pentaerythritol tetranitrate reductase containing a bound acetate molecule
分子名称: ACETATE ION, FLAVIN MONONUCLEOTIDE, Pentaerythritol tetranitrate reductase
著者Toogood, H.S, Scrutton, N.S.
登録日2010-10-11
公開日2010-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Focused Directed Evolution of Pentaerythritol Tetranitrate Reductase by Using Automated Anaerobic Kinetic Screening of Site-Saturated Libraries
Chembiochem, 11, 2010
3P74
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H181N mutant of pentaerythritol tetranitrate reductase containing a C-terminal His8-tag
分子名称: FLAVIN MONONUCLEOTIDE, Pentaerythritol tetranitrate reductase
著者Toogood, H.S, Scrutton, N.S.
登録日2010-10-12
公開日2011-03-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献A Site-Saturated Mutagenesis Study of Pentaerythritol Tetranitrate Reductase Reveals that Residues 181 and 184 Influence Ligand Binding, Stereochemistry and Reactivity.
Chembiochem, 12, 2011
3P8J
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BU of 3p8j by Molmil
Y351S mutant of pentaerythritol tetranitrate reductase containing a bound acetate molecule
分子名称: ACETATE ION, FLAVIN MONONUCLEOTIDE, Pentaerythritol tetranitrate reductase
著者Toogood, H.S, Scrutton, N.S.
登録日2010-10-14
公開日2011-04-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Active site modifications in pentaerythritol tetranitrate reductase can lead to improved product enantiopurity, decreased by-product formation and altered stereochemical outcome in reactions with a,b-unsaturated nitroolefins
Catalysis Science and Technology, 2011
3P84
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Y351A mutant of pentaerythritol tetranitrate reductase containing a bound acetate molecule
分子名称: ACETATE ION, FLAVIN MONONUCLEOTIDE, Pentaerythritol tetranitrate reductase
著者Toogood, H.S, Scrutton, N.S.
登録日2010-10-13
公開日2011-04-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Active site modifications in pentaerythritol tetranitrate reductase can lead to improved product enantiopurity, decreased by-product formation and altered stereochemical outcome in reactions with a,b-unsaturated nitroolefins
Catalysis Science and Technology, 2011
4HFN
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X-ray Crystal Structure of a Ternary Complex of Double Bond Reductase from Nicotiana tabacum
分子名称: (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enal, Allyl alcohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Toogood, H.S, Scrutton, N.S.
登録日2012-10-05
公開日2013-01-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Biocatalytic Asymmetric Alkene Reduction: Crystal Structure and Characterization of a Double Bond Reductase fromNicotiana tabacum.
ACS Catal, 3, 2013
4J31
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Crystal Structure of kynurenine 3-monooxygenase (KMO-396Prot)
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
著者Amaral, M, Levy, C, Heyes, D.J, Lafite, P, Outeiro, T.F, Giorgini, F, Leys, D, Scrutton, N.S.
登録日2013-02-05
公開日2013-04-10
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of kynurenine 3-monooxygenase inhibition.
Nature, 496, 2013
4J2W
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Crystal Structure of kynurenine 3-monooxygenase (KMO-396Prot-Se)
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
著者Amaral, M, Levy, C, Heyes, D.J, Lafite, P, Outeiro, T.F, Giorgini, F, Leys, D, Scrutton, N.S.
登録日2013-02-05
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of kynurenine 3-monooxygenase inhibition.
Nature, 496, 2013
4HFM
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X-ray Crystal Structure of a NADP(H)-bound Double Bond Reductase from Nicotiana tabacum
分子名称: Allyl alcohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Toogood, H.S, Scrutton, N.S.
登録日2012-10-05
公開日2013-01-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Biocatalytic Asymmetric Alkene Reduction: Crystal Structure and Characterization of a Double Bond Reductase fromNicotiana tabacum.
ACS Catal, 3, 2013
4GU5
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BU of 4gu5 by Molmil
Structure of Full-length Drosophila Cryptochrome
分子名称: Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION
著者Zoltowski, B.D, Vaidya, A.T, Top, D, Widom, J, Young, M.W, Levy, C, Jones, A.R, Scrutton, N.S, Leys, D, Crane, B.R.
登録日2012-08-29
公開日2012-09-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Updated structure of Drosophila cryptochrome.
Nature, 495, 2013
4HFJ
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BU of 4hfj by Molmil
X-ray Crystal Structure of a Double Bond Reductase from Nicotiana tabacum
分子名称: Allyl alcohol dehydrogenase
著者Toogood, H.S, Scrutton, N.S.
登録日2012-10-05
公開日2013-01-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Biocatalytic Asymmetric Alkene Reduction: Crystal Structure and Characterization of a Double Bond Reductase fromNicotiana tabacum.
ACS Catal, 3, 2013

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