1WET
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![BU of 1wet by Molmil](/molmil-images/mine/1wet) | STRUCTURE OF THE PURR-GUANINE-PURF OPERATOR COMPLEX | Descriptor: | DNA (5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*TP*TP*TP*TP*CP*GP*T )-3'), GUANINE, PROTEIN (PURINE REPRESSOR) | Authors: | Schumacher, M.A, Glasfeld, A, Zalkin, H, Brennan, R.G. | Deposit date: | 1997-04-27 | Release date: | 1997-11-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The X-ray structure of the PurR-guanine-purF operator complex reveals the contributions of complementary electrostatic surfaces and a water-mediated hydrogen bond to corepressor specificity and binding affinity. J.Biol.Chem., 272, 1997
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8TPK
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![BU of 8tpk by Molmil](/molmil-images/mine/8tpk) | P6522 crystal form of C. crescentus DriD-ssDNA-DNA complex | Descriptor: | DNA (5'-D(*AP*TP*AP*CP*GP*AP*CP*AP*GP*TP*AP*AP*CP*TP*GP*TP*CP*GP*TP*AP*T)-3'), DNA (5'-D(*AP*TP*AP*CP*GP*AP*CP*AP*GP*TP*TP*AP*CP*TP*GP*TP*CP*GP*TP*AP*T)-3'), DNA (5'-D(P*GP*TP*C)-3'), ... | Authors: | Schumacher, M.A. | Deposit date: | 2023-08-04 | Release date: | 2023-11-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.46 Å) | Cite: | Structure of the WYL-domain containing transcription activator, DriD, in complex with ssDNA effector and DNA target site. Nucleic Acids Res., 52, 2024
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5K5O
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![BU of 5k5o by Molmil](/molmil-images/mine/5k5o) | Structure of AspA-26mer DNA complex | Descriptor: | AspA, DNA (26-MER) | Authors: | Schumacher, M. | Deposit date: | 2016-05-23 | Release date: | 2016-06-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Science, 349, 2015
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7U3A
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![BU of 7u3a by Molmil](/molmil-images/mine/7u3a) | Structure of the Streptomyces venezuelae GlgX-c-di-GMP complex | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Glycogen debranching enzyme GlgX | Authors: | Schumacher, M.A. | Deposit date: | 2022-02-26 | Release date: | 2022-10-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.34 Å) | Cite: | Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP. Nat Commun, 13, 2022
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3VEA
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![BU of 3vea by Molmil](/molmil-images/mine/3vea) | Crystal Structure of matP-matS23mer | Descriptor: | 5'-D(*AP*GP*TP*TP*CP*GP*TP*GP*AP*CP*AP*AP*TP*GP*TP*CP*AP*CP*GP*AP*AP*CP*T)-3', 5'-D(*AP*GP*TP*TP*CP*GP*TP*GP*AP*CP*AP*TP*TP*GP*TP*CP*AP*CP*GP*AP*AP*CP*T)-3', Macrodomain Ter protein | Authors: | Schumacher, M.A. | Deposit date: | 2012-01-07 | Release date: | 2012-11-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Molecular basis for a protein-mediated DNA-bridging mechanism that functions in condensation of the E. coli chromosome. Mol.Cell, 48, 2012
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6UEP
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![BU of 6uep by Molmil](/molmil-images/mine/6uep) | |
6UEO
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![BU of 6ueo by Molmil](/molmil-images/mine/6ueo) | Structure of A. thaliana TBP-AC mismatch DNA site | Descriptor: | DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*CP*TP*TP*TP*AP*TP*AP*GP*C)-3'), TATA-box-binding protein 1 | Authors: | Schumacher, M.A. | Deposit date: | 2019-09-22 | Release date: | 2020-09-02 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | DNA mismatches reveal conformational penalties in protein-DNA recognition. Nature, 587, 2020
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6UER
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![BU of 6uer by Molmil](/molmil-images/mine/6uer) | |
6UEQ
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![BU of 6ueq by Molmil](/molmil-images/mine/6ueq) | Structure of TBP bound to C-C mismatch containing TATA site | Descriptor: | DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*AP*CP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*C)-3'), SULFATE ION, ... | Authors: | Schumacher, M.A, Al-Hashimi, H. | Deposit date: | 2019-09-22 | Release date: | 2020-09-02 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | DNA mismatches reveal conformational penalties in protein-DNA recognition. Nature, 587, 2020
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5TZG
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![BU of 5tzg by Molmil](/molmil-images/mine/5tzg) | Structure of the BldD CTD(D116A)-(c-di-GMP)2, form 2 | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein, ZINC ION | Authors: | Schumacher, M.A. | Deposit date: | 2016-11-21 | Release date: | 2017-04-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex. Nucleic Acids Res., 45, 2017
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7TDV
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![BU of 7tdv by Molmil](/molmil-images/mine/7tdv) | |
7TZV
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![BU of 7tzv by Molmil](/molmil-images/mine/7tzv) | Structure of DriD C-domain bound to 9mer ssDNA | Descriptor: | DNA (5'-D(*TP*AP*GP*TP*CP*TP*AP*CP*T)-3'), WYL domain-containing protein | Authors: | Schumacher, M.A, Laub, M. | Deposit date: | 2022-02-16 | Release date: | 2022-06-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | ssDNA is an allosteric regulator of the C. crescentus SOS-independent DNA damage response transcription activator, DriD. Genes Dev., 36, 2022
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6WEG
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![BU of 6weg by Molmil](/molmil-images/mine/6weg) | |
2NTZ
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![BU of 2ntz by Molmil](/molmil-images/mine/2ntz) | |
2NZV
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![BU of 2nzv by Molmil](/molmil-images/mine/2nzv) | Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors G6P and FBP | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, Catabolite control protein, Phosphocarrier protein HPr, ... | Authors: | Schumacher, M.A, Hillen, W, Brennan, R.G. | Deposit date: | 2006-11-25 | Release date: | 2007-05-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Mechanism for the Fine-tuning of CcpA Function by The Small Molecule Effectors Glucose 6-Phosphate and Fructose 1,6-Bisphosphate. J.Mol.Biol., 368, 2007
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3VEB
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![BU of 3veb by Molmil](/molmil-images/mine/3veb) | Crystal Structure of Matp-matS | Descriptor: | 5'-D(*AP*CP*GP*TP*GP*AP*CP*AP*AP*TP*GP*TP*CP*AP*CP*G)-3', 5'-D(*TP*CP*GP*TP*GP*AP*CP*AP*TP*TP*GP*TP*CP*AP*CP*G)-3', CALCIUM ION, ... | Authors: | Schumacher, M.A. | Deposit date: | 2012-01-07 | Release date: | 2012-11-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular basis for a protein-mediated DNA-bridging mechanism that functions in condensation of the E. coli chromosome. Mol.Cell, 48, 2012
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2OEN
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![BU of 2oen by Molmil](/molmil-images/mine/2oen) | Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors glucose-6-phosphate and fructose-1,6-bisphosphate | Descriptor: | Catabolite control protein, Phosphocarrier protein HPr | Authors: | Schumacher, M.A, Seidel, G, Hillen, W, Brennan, R.G. | Deposit date: | 2006-12-30 | Release date: | 2007-05-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.17 Å) | Cite: | Structural Mechanism for the Fine-tuning of CcpA Function by The Small Molecule Effectors Glucose 6-Phosphate and Fructose 1,6-Bisphosphate. J.Mol.Biol., 368, 2007
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3TPB
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![BU of 3tpb by Molmil](/molmil-images/mine/3tpb) | Structure of HipA(S150A) | Descriptor: | CHLORIDE ION, PHOSPHATE ION, Serine/threonine-protein kinase HipA | Authors: | schumacher, M.A. | Deposit date: | 2011-09-07 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance. Cell Rep, 2, 2012
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3TPV
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![BU of 3tpv by Molmil](/molmil-images/mine/3tpv) | Structure of pHipA bound to ADP | Descriptor: | ADENINE, SULFATE ION, Serine/threonine-protein kinase HipA | Authors: | Schumacher, M.A, Link, T.M, Brennan, R.G. | Deposit date: | 2011-09-08 | Release date: | 2012-10-03 | Last modified: | 2012-10-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance. Cell Rep, 2, 2012
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6AMA
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![BU of 6ama by Molmil](/molmil-images/mine/6ama) | |
2GID
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![BU of 2gid by Molmil](/molmil-images/mine/2gid) | Crystal structures of trypanosoma bruciei MRP1/MRP2 | Descriptor: | mitochondrial RNA-binding protein 1, mitochondrial RNA-binding protein 2 | Authors: | Schumacher, M.A, Karamooz, E, Zikova, A, Trantirek, L, Lukes, J. | Deposit date: | 2006-03-28 | Release date: | 2006-09-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Crystal Structures of T. brucei MRP1/MRP2 Guide-RNA Binding Complex Reveal RNA Matchmaking Mechanism. Cell(Cambridge,Mass.), 126, 2006
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7TEA
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![BU of 7tea by Molmil](/molmil-images/mine/7tea) | Crystal structure of S. aureus GlnR-DNA complex | Descriptor: | CALCIUM ION, DNA (5'-D(*CP*GP*TP*GP*TP*CP*AP*GP*AP*TP*AP*AP*TP*CP*TP*GP*AP*CP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*GP*TP*CP*AP*GP*AP*TP*TP*AP*TP*CP*TP*GP*AP*CP*AP*CP*G)-3'), ... | Authors: | Schumacher, M.A. | Deposit date: | 2022-01-04 | Release date: | 2022-06-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nat Commun, 13, 2022
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7TDP
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![BU of 7tdp by Molmil](/molmil-images/mine/7tdp) | |
7TEN
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![BU of 7ten by Molmil](/molmil-images/mine/7ten) | |
5E1L
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![BU of 5e1l by Molmil](/molmil-images/mine/5e1l) | Structural and functional analysis of the E. coli FtsZ interacting protein, ZapC, reveals insight into molecular properties of a novel Z ring stabilizing protein | Descriptor: | Cell division protein ZapC | Authors: | Schumacher, M.A, Huang, K.-H, Tchorzewski, L, Zeng, W, Janakiraman, A. | Deposit date: | 2015-09-29 | Release date: | 2015-12-23 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural and Functional Analyses Reveal Insights into the Molecular Properties of the Escherichia coli Z Ring Stabilizing Protein, ZapC. J.Biol.Chem., 291, 2016
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