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PDB: 7 件
8B7H
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BU of 8b7h by Molmil
Crystal structure of human Gremlin-1 in complex with Fab
分子名称: Fab antibody fragment (heavy chain), Fab antibody fragment (light chain), Gremlin-1
著者Schulze, M.-S, Martinez-Fleites, C.
登録日2022-09-30
公開日2023-12-27
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Discovery of ginisortamab, a potent and novel anti-gremlin-1 antibody in clinical development for the treatment of cancer.
Mabs, 15, 2023
8CDG
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BU of 8cdg by Molmil
Crystal structure of human IL-17A cytokine in complex with macrocycle
分子名称: (9~{S},12~{R},19~{S})-9-[[4-[[(2~{S})-2-cyclohexyl-2-(2-phenylethanoylamino)ethanoyl]amino]phenyl]methyl]-12-methyl-7,10,13,21-tetrakis(oxidanylidene)-8,11,14,20-tetrazaspiro[4.17]docosane-19-carboxylic acid, Interleukin-17A
著者Schulze, M.-S.
登録日2023-01-30
公開日2023-12-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Modulation of IL-17 backbone dynamics reduces receptor affinity and reveals a new inhibitory mechanism.
Chem Sci, 14, 2023
4I5B
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BU of 4i5b by Molmil
Structure of human MHC class II protein HLA-DR1 carrying an influenza hemagglutinin peptide partially filling the binding groove
分子名称: HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
著者Schulze, M.-S.E.D.
登録日2012-11-28
公開日2013-12-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Disruption of hydrogen bonds between major histocompatibility complex class II and the peptide N-terminus is not sufficient to form a human leukocyte antigen-DM receptive state of major histocompatibility complex class II.
Plos One, 8, 2013
6GY1
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BU of 6gy1 by Molmil
rat COMT in complex with inhibitor
分子名称: 7-fluoranyl-5-(4-methylphenyl)sulfonyl-quinolin-8-ol, Catechol O-methyltransferase, DIMETHYL SULFOXIDE, ...
著者Schulze, M.-S.
登録日2018-06-27
公開日2018-10-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Optimization of 8-Hydroxyquinolines as Inhibitors of Catechol O-Methyltransferase.
J. Med. Chem., 61, 2018
8P3E
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BU of 8p3e by Molmil
Crystal structure of glucocerebrosidase in complex with allosteric activator
分子名称: 2-[[3-[(4-chlorophenyl)carbamoyl]phenyl]sulfonylamino]benzoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Schulze, M.-S.
登録日2023-05-17
公開日2024-03-06
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Identification of ss-Glucocerebrosidase Activators for Glucosylceramide hydrolysis.
Chemmedchem, 19, 2024
8P41
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Crystal structure of glucocerebrosidase in complex with allosteric activator
分子名称: 2-[2-[[3,5-bis(trifluoromethyl)phenyl]methylsulfanyl]ethanoylamino]-5-chloranyl-benzoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Schulze, M.-S.
登録日2023-05-18
公開日2024-03-06
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Identification of ss-Glucocerebrosidase Activators for Glucosylceramide hydrolysis.
Chemmedchem, 19, 2024
2V9U
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BU of 2v9u by Molmil
Rim domain of main porin from Mycobacteria smegmatis
分子名称: MSPA
著者Grueninger, D, Ziegler, M.O.P, Koetter, J.W.A, Treiber, N, Schulze, M.-S, Schulz, G.E.
登録日2007-08-27
公開日2008-01-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Designed Protein-Protein Association.
Science, 319, 2008

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件を2024-10-30に公開中

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