1JLJ
 
 | | 1.6 Angstrom crystal structure of the human neuroreceptor anchoring and molybdenum cofactor biosynthesis protein gephyrin | | Descriptor: | FORMIC ACID, SODIUM ION, gephyrin | | Authors: | Schwarz, G, Schrader, N, Mendel, R.R, Hecht, H.-J, Schindelin, H. | | Deposit date: | 2001-07-16 | | Release date: | 2001-09-21 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structures of human gephyrin and plant Cnx1 G domains: comparative analysis and functional implications.
J.Mol.Biol., 312, 2001
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7PVN
 | | Crystal Structure of Human UBA6 in Complex with ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Truongvan, N, Li, S, Schindelin, H. | | Deposit date: | 2021-10-05 | | Release date: | 2022-08-31 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Structures of UBA6 explain its dual specificity for ubiquitin and FAT10.
Nat Commun, 13, 2022
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1RGC
 | | THE COMPLEX BETWEEN RIBONUCLEASE T1 AND 3'-GUANYLIC ACID SUGGESTS GEOMETRY OF ENZYMATIC REACTION PATH. AN X-RAY STUDY | | Descriptor: | CALCIUM ION, GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE T1 | | Authors: | Heydenreich, A, Koellner, G, Choe, H.W, Cordes, F, Kisker, C, Schindelin, H, Adamiak, R, Hahn, U, Saenger, W. | | Deposit date: | 1993-05-12 | | Release date: | 1994-01-31 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The complex between ribonuclease T1 and 3'GMP suggests geometry of enzymic reaction path. An X-ray study.
Eur.J.Biochem., 218, 1993
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7POE
 | | Phosphoglycolate Phosphatase with Inhibitor CP1 | | Descriptor: | 2-[[4-[4-[(2-carboxyphenyl)carbamoyl]phenoxy]phenyl]carbonylamino]benzoic acid, GLYCEROL, Glycerol-3-phosphate phosphatase, ... | | Authors: | Schloetzer, J, Fratz, S, Schindelin, H. | | Deposit date: | 2021-09-08 | | Release date: | 2022-12-21 | | Last modified: | 2024-07-03 | | Method: | X-RAY DIFFRACTION (3.16 Å) | | Cite: | Glycolytic flux control by drugging phosphoglycolate phosphatase.
Nat Commun, 13, 2022
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3ESW
 | | Complex of yeast PNGase with GlcNAc2-IAc. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase, UV excision repair protein RAD23, ... | | Authors: | Zhao, G, Zhou, X, Lennarz, W.J, Schindelin, H. | | Deposit date: | 2008-10-06 | | Release date: | 2008-11-11 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural and mutational studies on the importance of oligosaccharide binding for the activity of yeast PNGase.
Glycobiology, 19, 2009
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5YPY
 | | Crystal structure of IlvN. Val-1c | | Descriptor: | Acetolactate synthase isozyme 1 small subunit, VALINE | | Authors: | Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B. | | Deposit date: | 2017-11-04 | | Release date: | 2018-09-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.966 Å) | | Cite: | Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases.
Biochemistry, 58, 2019
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4MT7
 | | Crystal structure of collybistin I | | Descriptor: | Rho guanine nucleotide exchange factor 9 | | Authors: | Schneeberger, D, Schindelin, H. | | Deposit date: | 2013-09-19 | | Release date: | 2014-08-13 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | A conformational switch in collybistin determines the differentiation of inhibitory postsynapses.
Embo J., 33, 2014
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4MT6
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3TIW
 | | Crystal structure of p97N in complex with the C-terminus of gp78 | | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase AMFR, Transitional endoplasmic reticulum ATPase | | Authors: | Haenzelmann, P, Schindelin, H. | | Deposit date: | 2011-08-22 | | Release date: | 2011-09-14 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.802 Å) | | Cite: | The Structural and Functional Basis of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM): MUTUALLY EXCLUSIVE BINDING OF COFACTORS TO THE N-TERMINAL DOMAIN OF p97.
J.Biol.Chem., 286, 2011
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6HSN
 | | Crystal structure of the ternary complex of GephE-ADP-GABA(A) receptor derived peptide | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,1'-[ethane-1,2-diylbis(oxyethane-2,1-diyl)]bis(1H-pyrrole-2,5-dione), ACETATE ION, ... | | Authors: | Kasaragod, V.B, Schindelin, H. | | Deposit date: | 2018-10-01 | | Release date: | 2019-01-16 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins.
Neuron, 101, 2019
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6GXG
 | | Tryparedoxin from Trypanosoma brucei in complex with CFT | | Descriptor: | 5-(4-fluorophenyl)-2-methyl-3~{H}-thieno[2,3-d]pyrimidin-4-one, GLYCEROL, Tryparedoxin | | Authors: | Bader, N, Wagner, A, Hellmich, U, Schindelin, H. | | Deposit date: | 2018-06-27 | | Release date: | 2019-01-16 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Inhibitor-Induced Dimerization of an Essential Oxidoreductase from African Trypanosomes.
Angew. Chem. Int. Ed. Engl., 58, 2019
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6HSO
 | | Crystal structure of the ternary complex of GephE-ADP-Glycine receptor derived peptide | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,1'-benzene-1,4-diylbis(1H-pyrrole-2,5-dione), ACETATE ION, ... | | Authors: | Kasaragod, V.B, Schindelin, H. | | Deposit date: | 2018-10-01 | | Release date: | 2019-01-16 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins.
Neuron, 101, 2019
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6HRS
 | | Structure of the TRPML2 ELD at pH 4.5 | | Descriptor: | GLYCEROL, Mucolipin-2 | | Authors: | Bader, N, Viet, K.K, Wagner, A, Hellmich, U.A, Schindelin, H. | | Deposit date: | 2018-09-28 | | Release date: | 2019-06-19 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Structure of the Human TRPML2 Ion Channel Extracytosolic/Lumenal Domain.
Structure, 27, 2019
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5YUM
 | | Crystallographic structures of IlvN.Val/Ile complexes:Conformational selectivity for feedback inhibition of AHASs | | Descriptor: | Acetolactate synthase isozyme 1 small subunit, COBALT (II) ION, ISOLEUCINE | | Authors: | Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B. | | Deposit date: | 2017-11-22 | | Release date: | 2018-09-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.432 Å) | | Cite: | Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases.
Biochemistry, 58, 2019
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2HBB
 | | Crystal Structure of the N-terminal Domain of Ribosomal Protein L9 (NTL9) | | Descriptor: | 50S ribosomal protein L9, ZINC ION | | Authors: | Cho, J.-H, Kim, E.Y, Schindelin, H, Raleigh, D.P. | | Deposit date: | 2006-06-14 | | Release date: | 2007-05-29 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Energetically significant networks of coupled interactions within an unfolded protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4F9Z
 | | Crystal Structure of human ERp27 | | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ACETATE ION, ... | | Authors: | Kober, F.X, Koelmel, W, Kuper, J, Schindelin, H. | | Deposit date: | 2012-05-21 | | Release date: | 2012-12-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Crystal Structure of the Protein-Disulfide Isomerase Family Member ERp27 Provides Insights into Its Substrate Binding Capabilities.
J.Biol.Chem., 288, 2013
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6I0Q
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5AES
 | | Crystal Structure of murine Chronophin (Pyridoxal Phosphate Phosphatase) in Complex with a PNP-derived Inhibitor | | Descriptor: | GLYCEROL, MAGNESIUM ION, PYRIDOXAL PHOSPHATE PHOSPHATASE, ... | | Authors: | Knobloch, G, Jabari, N, Koehn, M, Gohla, A, Schindelin, H. | | Deposit date: | 2015-01-09 | | Release date: | 2015-04-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.751 Å) | | Cite: | Synthesis of Hydrolysis-Resistant Pyridoxal 5'-Phosphate Analogs and Their Biochemical and X-Ray Crystallographic Characterization with the Pyridoxal Phosphatase Chronophin.
Bioorg.Med.Chem., 23, 2015
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5C1B
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2HBA
 | | Crystal Structure of N-terminal Domain of Ribosomal Protein L9 (NTL9) K12M | | Descriptor: | 50S ribosomal protein L9, CHLORIDE ION, IMIDAZOLE, ... | | Authors: | Cho, J.-H, Kim, E.Y, Schindelin, H, Raleigh, D.P. | | Deposit date: | 2006-06-14 | | Release date: | 2007-05-29 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Energetically significant networks of coupled interactions within an unfolded protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
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5C18
 | | p97-delta709-728 in complex with ATP-gamma-S | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Haenzelmann, P, Schindelin, H. | | Deposit date: | 2015-06-13 | | Release date: | 2016-01-13 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structural Basis of ATP Hydrolysis and Intersubunit Signaling in the AAA+ ATPase p97.
Structure, 24, 2016
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5C19
 | | p97 variant 2 in the apo state | | Descriptor: | SULFATE ION, Transitional endoplasmic reticulum ATPase | | Authors: | Haenzelmann, P, Schindelin, H. | | Deposit date: | 2015-06-13 | | Release date: | 2016-01-13 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (4.2 Å) | | Cite: | Structural Basis of ATP Hydrolysis and Intersubunit Signaling in the AAA+ ATPase p97.
Structure, 24, 2016
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2HVF
 | | Crystal Structure of N-terminal Domain of Ribosomal Protein L9 (NTL9), G34dA | | Descriptor: | 50S ribosomal protein L9, ACETIC ACID, CHLORIDE ION, ... | | Authors: | Anil, B, Kim, E.Y, Cho, J.H, Schindelin, H, Raleigh, D.P. | | Deposit date: | 2006-07-28 | | Release date: | 2007-06-12 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | Detecting and quantifying strain in protein folding
To be Published
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1SOX
 | | SULFITE OXIDASE FROM CHICKEN LIVER | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, MOLYBDENUM ATOM, ... | | Authors: | Kisker, C, Schindelin, H, Rees, D.C. | | Deposit date: | 1997-12-31 | | Release date: | 1998-04-29 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Molecular basis of sulfite oxidase deficiency from the structure of sulfite oxidase.
Cell(Cambridge,Mass.), 91, 1997
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3R3M
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