7JSK
 
 | | Structure of the NaCT-Citrate complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, SODIUM ION, ... | | Authors: | Sauer, D.B, Wang, B, Song, J, Rice, W.J, Wang, D.N. | | Deposit date: | 2020-08-14 | | Release date: | 2021-02-24 | | Last modified: | 2021-03-10 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Structure and inhibition mechanism of the human citrate transporter NaCT.
Nature, 591, 2021
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7JSJ
 | | Structure of the NaCT-PF2 complex | | Descriptor: | (2R)-2-[2-(4-tert-butylphenyl)ethyl]-2-hydroxybutanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ... | | Authors: | Sauer, D.B, Wang, B, Song, J, Rice, W.J, Wang, D.N. | | Deposit date: | 2020-08-14 | | Release date: | 2021-02-24 | | Last modified: | 2021-03-10 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Structure and inhibition mechanism of the human citrate transporter NaCT.
Nature, 591, 2021
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6WTX
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6WW5
 | | Structure of VcINDY-Na-Fab84 in nanodisc | | Descriptor: | 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, DASS family sodium-coupled anion symporter, Fab84 Heavy Chain, ... | | Authors: | Sauer, D.B, Marden, J, Song, J.M, Koide, A, Koide, S, Wang, D.N. | | Deposit date: | 2020-05-07 | | Release date: | 2020-09-16 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
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6WTW
 | | Structure of LaINDY crystallized in the presence of alpha-ketoglutarate and malate | | Descriptor: | DASS family sodium-coupled anion symporter | | Authors: | Sauer, D.B, Cocco, N, Marden, J.J, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2020-05-04 | | Release date: | 2020-09-16 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
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6WU1
 | | Structure of apo LaINDY | | Descriptor: | DASS family sodium-coupled anion symporter, DECANE, HEXANE, ... | | Authors: | Sauer, D.B, Marden, J.J, Cocco, N.C, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2020-05-04 | | Release date: | 2020-09-16 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
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6WU2
 | | Structure of the LaINDY-malate complex | | Descriptor: | DASS family sodium-coupled anion symporter, DECANE, HEXANE, ... | | Authors: | Sauer, D.B, Marden, J.J, Cocco, N, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2020-05-04 | | Release date: | 2020-09-16 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.36 Å) | | Cite: | Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
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6WU3
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6WU4
 | | Structure of the LaINDY-alpha-ketoglutarate complex | | Descriptor: | DASS family sodium-coupled anion symporter | | Authors: | Sauer, D.B, Marden, J.J, Cocco, N, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2020-05-04 | | Release date: | 2020-09-16 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.71 Å) | | Cite: | Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
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7T9F
 | | Structure of VcINDY-apo | | Descriptor: | DASS family sodium-coupled anion symporter | | Authors: | Sauer, D.B, Marden, J.J, Song, J.M, Wang, D.N. | | Deposit date: | 2021-12-19 | | Release date: | 2022-05-25 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | Structural basis of ion - substrate coupling in the Na + -dependent dicarboxylate transporter VcINDY.
Nat Commun, 13, 2022
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7T9G
 | | Structure of VcINDY-Na+ | | Descriptor: | DASS family sodium-coupled anion symporter, SODIUM ION | | Authors: | Sauer, D.B, Marden, J.J, Song, J.M, Wang, D.N. | | Deposit date: | 2021-12-19 | | Release date: | 2022-05-25 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.83 Å) | | Cite: | Structural basis of ion - substrate coupling in the Na + -dependent dicarboxylate transporter VcINDY.
Nat Commun, 13, 2022
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6OL0
 | | Structure of VcINDY bound to Malate | | Descriptor: | (2S)-2-hydroxybutanedioic acid, SODIUM ION, Transporter, ... | | Authors: | Sauer, D.B, Marden, J.J, Wang, D.N. | | Deposit date: | 2019-04-15 | | Release date: | 2020-10-28 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.502 Å) | | Cite: | Elevator mechanism dynamics in a sodium-coupled dicarboxylate transporter
Biorxiv, 2022
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6OL1
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6OKZ
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3TET
 | | Crystal Structure of NaK2K Channel Y66F Mutant | | Descriptor: | POTASSIUM ION, Potassium channel protein | | Authors: | Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y. | | Deposit date: | 2011-08-15 | | Release date: | 2011-10-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3T4Z
 | | Crystal Structure of NaK2K Channel Y55W Mutant | | Descriptor: | POTASSIUM ION, Potassium channel protein | | Authors: | Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y. | | Deposit date: | 2011-07-26 | | Release date: | 2011-10-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.901 Å) | | Cite: | Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3TCU
 | | Crystal Structure of NaK2K Channel D68E Mutant | | Descriptor: | POTASSIUM ION, Potassium channel protein | | Authors: | Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y. | | Deposit date: | 2011-08-09 | | Release date: | 2011-10-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3T1C
 | | Crystal Structure of NaK Channel D66Y Mutant | | Descriptor: | POTASSIUM ION, Potassium channel protein | | Authors: | Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y. | | Deposit date: | 2011-07-21 | | Release date: | 2011-10-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.802 Å) | | Cite: | Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3T2M
 | | Crystal Structure of NaK Channel N68D Mutant | | Descriptor: | POTASSIUM ION, Potassium channel protein | | Authors: | Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y. | | Deposit date: | 2011-07-22 | | Release date: | 2011-10-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.953 Å) | | Cite: | Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3T4D
 | | Crystal Structure of NaK2K Channel Y55F Mutant | | Descriptor: | POTASSIUM ION, Potassium channel protein | | Authors: | Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y. | | Deposit date: | 2011-07-25 | | Release date: | 2011-10-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation.
Proc.Natl.Acad.Sci.USA, 108, 2011
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4GX1
 | | Crystal structure of the GsuK bound to ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, PHOSPHATE ION, ... | | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | | Deposit date: | 2012-09-03 | | Release date: | 2012-12-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel.
elife, 1, 2012
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4GX2
 | | GsuK channel bound to NAD | | Descriptor: | CALCIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, ... | | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | | Deposit date: | 2012-09-03 | | Release date: | 2012-12-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel.
elife, 1, 2012
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7LO8
 | | NorA in complex with Fab36 | | Descriptor: | Fab36 Heavy Chain, Fab36 Light Chain, Quinolone resistance protein NorA | | Authors: | Brawley, D.N, Sauer, D.B, Song, J.M, Koide, A, Koide, S, Traaseth, N.J, Wang, D.N. | | Deposit date: | 2021-02-09 | | Release date: | 2022-04-20 | | Last modified: | 2022-07-13 | | Method: | ELECTRON MICROSCOPY (3.16 Å) | | Cite: | Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus.
Nat.Chem.Biol., 18, 2022
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7LO7
 | | NorA in complex with Fab25 | | Descriptor: | Fab25 Heavy Chain, Fab25 Light Chain, Quinolone resistance protein NorA | | Authors: | Brawley, D.N, Sauer, D.B, Song, J.M, Koide, A, Koide, S, Traaseth, N.J, Wang, D.N. | | Deposit date: | 2021-02-09 | | Release date: | 2022-04-20 | | Last modified: | 2022-07-13 | | Method: | ELECTRON MICROSCOPY (3.74 Å) | | Cite: | Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus.
Nat.Chem.Biol., 18, 2022
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7BBM
 | | Mutant nitrobindin M75L/H76L/Q96C/M148L (NB4H) from Arabidopsis thaliana with cofactor MnPPIX | | Descriptor: | 1,2-ETHANEDIOL, MANGANESE PROTOPORPHYRIN IX, UPF0678 fatty acid-binding protein-like protein At1g79260 | | Authors: | Minges, A, Sauer, D.F, Wittwer, M, Markel, U, Spiertz, M, Schiffels, J, Davari, M.D, Okuda, J, Schwaneberg, U, Groth, G. | | Deposit date: | 2020-12-18 | | Release date: | 2021-05-26 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.14 Å) | | Cite: | Chemogenetic engineering of nitrobindin toward an artificial epoxygenase
Catalysis Science And Technology, 2021
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