6VBS
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8FXQ
| The Crystal Sturucture of Rhizopuspepsin with a bound modified peptide inhibitor generated by de novo drug design. | Descriptor: | ALA-CYS-VAL-LYS, CYCLOHEXANE, Rhizopuspepsin, ... | Authors: | Satyshur, K.A, Rich, D.H, Ripka, A.S. | Deposit date: | 2023-01-25 | Release date: | 2023-02-08 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Aspartic protease inhibitors designed from computer-generated templates bind as predicted. Org Lett, 3, 2001
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6DGD
| PriA helicase bound to dsDNA of a DNA replication fork | Descriptor: | DNA (5'-D(P*AP*GP*CP*AP*CP*GP*CP*CP*GP*AP*CP*T)-3'), DNA (5'-D(P*GP*AP*GP*CP*AP*CP*GP*CP*CP*GP*AP*CP*T)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*CP*GP*TP*GP*CP*TP*C)-3'), ... | Authors: | Satyshur, K.A, Windgassen, T.A, Keck, J.L. | Deposit date: | 2018-05-17 | Release date: | 2018-09-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.823 Å) | Cite: | Structure-specific DNA replication-fork recognition directs helicase and replication restart activities of the PriA helicase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6D9R
| The substrate-bound crystal structure of HPRT (hypoxanthine phosphoribosyltransferase) | Descriptor: | 1,2-ETHANEDIOL, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 9-DEAZAGUANINE, ... | Authors: | Satyshur, K.A, Wolak, C, Anderson, B, Dubiel, K, Keck, J.L. | Deposit date: | 2018-04-30 | Release date: | 2019-05-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction. Elife, 8, 2019
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6D9S
| The (p)ppGpp-bound crystal structure of HPRT (hypoxanthine phosphoribosyltransferase) | Descriptor: | DI(HYDROXYETHYL)ETHER, GUANOSINE-5',3'-TETRAPHOSPHATE, Hypoxanthine phosphoribosyltransferase, ... | Authors: | Satyshur, K.A, Dubiel, K, Anderson, B, Wolak, C, Keck, J.L. | Deposit date: | 2018-04-30 | Release date: | 2019-05-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.105 Å) | Cite: | Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction. Elife, 8, 2019
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2EWW
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2EWV
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2EYU
| The Crystal Structure of the C-terminal Domain of Aquifex aeolicus PilT | Descriptor: | SULFATE ION, twitching motility protein PilT | Authors: | Satyshur, K.A, Worzalla, G.A, Meyer, L.S, Heiniger, E.K, Aukema, K.G, Forest, K.T. | Deposit date: | 2005-11-09 | Release date: | 2006-11-21 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Crystal structures of the pilus retraction motor PilT suggest large domain movements and subunit cooperation drive motility. Structure, 15, 2007
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3IPN
| Crystal Structure of fluorine and methyl modified collagen: (mepFlpgly)7 | Descriptor: | CARBONATE ION, Non-natural Collagen | Authors: | Satyshur, K.A, Shoulders, M.D, Raines, R.T, Forest, K.T. | Deposit date: | 2009-08-18 | Release date: | 2010-02-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Stereoelectronic and steric effects in side chains preorganize a protein main chain. Proc.Natl.Acad.Sci.USA, 107, 2010
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3HL8
| Crystal structure of exonuclease I in complex with inhibitor BCBP | Descriptor: | (5R)-3-tert-butyl-1-(6-chloro-1,3-benzothiazol-2-yl)-4,5-dihydro-1H-pyrazol-5-ol, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... | Authors: | Satyshur, K.A. | Deposit date: | 2009-05-27 | Release date: | 2010-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Small-molecule tools for dissecting the roles of SSB/protein interactions in genome maintenance Proc.Natl.Acad.Sci.USA, 107, 2010
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3HP9
| Crystal structure of SSB/Exonuclease I in complex with inhibitor CFAM | Descriptor: | 1,2-ETHANEDIOL, 2-{[2-chloro-5-(trifluoromethyl)phenyl]amino}-5-methoxybenzoic acid, DIMETHYL SULFOXIDE, ... | Authors: | Satyshur, K.A. | Deposit date: | 2009-06-03 | Release date: | 2010-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Small-molecule tools for dissecting the roles of SSB/protein interactions in genome maintenance Proc.Natl.Acad.Sci.USA, 107, 2010
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6VBT
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6W1I
| Re-interpretation of ppGpp (G4P) electron density in the deposited crystal structure of Xanthine phosphoribosyltransferase (XPRT) (1Y0B). | Descriptor: | GUANOSINE-5',3'-TETRAPHOSPHATE, SODIUM ION, Xanthine phosphoribosyltransferase | Authors: | Satyshur, K.A, Anderson, B.W, Keck, J.L, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2020-03-04 | Release date: | 2020-07-29 | Last modified: | 2021-04-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular Mechanism of Regulation of the Purine Salvage Enzyme XPRT by the Alarmones pppGpp, ppGpp, and pGpp. J.Mol.Biol., 432, 2020
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6D9Q
| The sulfate-bound crystal structure of HPRT (hypoxanthine phosphoribosyltransferase) | Descriptor: | GLYCEROL, Hypoxanthine phosphoribosyltransferase, SULFATE ION | Authors: | Satyshur, K.A, Dubiel, K, Anderson, B, Wolak, C, Keck, J.L. | Deposit date: | 2018-04-30 | Release date: | 2019-05-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.056 Å) | Cite: | Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction. Elife, 8, 2019
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6DCR
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3MXN
| Crystal structure of the RMI core complex | Descriptor: | BENZAMIDINE, RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2 | Authors: | Hoadley, K.A, Xu, D, Xue, Y, Satyshur, K.A, Wang, W, Keck, J.L. | Deposit date: | 2010-05-07 | Release date: | 2010-09-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure and cellular roles of the RMI core complex from the bloom syndrome dissolvasome. Structure, 18, 2010
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3NCT
| X-ray crystal structure of the bacterial conjugation factor PsiB, a negative regulator of reca | Descriptor: | Protein psiB | Authors: | Petrova, V, Satyshur, K.A, George, N.P, McCaslin, D, Cox, M.M, Keck, J.L. | Deposit date: | 2010-06-05 | Release date: | 2010-07-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | X-ray crystal structure of the bacterial conjugation factor PsiB, a negative regulator of RecA. J.Biol.Chem., 285, 2010
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5IC5
| Bacteriophytochrome response regulator RtBRR | Descriptor: | CACODYLATE ION, Candidate response regulator, CheY, ... | Authors: | Baker, A.W, Satyshur, K.A, Forest, K.T. | Deposit date: | 2016-02-22 | Release date: | 2016-03-02 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Arm-in-Arm Response Regulator Dimers Promote Intermolecular Signal Transduction. J.Bacteriol., 198, 2016
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2GSZ
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6D52
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4QRH
| Molecular mechanism and evolution of guanylate kinase regulation by (p)ppGpp | Descriptor: | 1,2-ETHANEDIOL, Guanylate kinase, MAGNESIUM ION, ... | Authors: | Liu, K, Krasny, K, Myers, A.R, Satyshur, K.A, Keck, J.L, Wnag, J.D. | Deposit date: | 2014-07-01 | Release date: | 2015-02-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Molecular Mechanism and Evolution of Guanylate Kinase Regulation by (p)ppGpp. Mol.Cell, 57, 2015
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6NQC
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6NIV
| Racemic Phenol-Soluble Modulin Alpha 3 Peptide | Descriptor: | Phenol-soluble modulin PSM-alpha-3 | Authors: | Yao, Z, Cary, B.P, Bingman, C.A, Wang, C, Kreitler, D.F, Satyshur, K.A, Forest, K.T, Gellman, S.H. | Deposit date: | 2018-12-31 | Release date: | 2019-05-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Use of a Stereochemical Strategy To Probe the Mechanism of Phenol-Soluble Modulin alpha 3 Toxicity. J.Am.Chem.Soc., 141, 2019
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7R7J
| Crystal structure of RadD with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative DNA repair helicase RadD, ... | Authors: | Osorio Garcia, M.A, Satyshur, K.A, Keck, J.L, Cox, M.M. | Deposit date: | 2021-06-24 | Release date: | 2022-04-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | X-ray crystal structure of the Escherichia coli RadD DNA repair protein bound to ADP reveals a novel zinc ribbon domain. Plos One, 17, 2022
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8FAK
| DNA replication fork binding triggers structural changes in the PriA DNA helicase that regulate the PriA-PriB replication restart pathway in E. coli | Descriptor: | DNA (5'-D(P*CP*AP*GP*AP*CP*TP*CP*AP*TP*TP*TP*AP*GP*CP*CP*CP*TP*TP*AP*TP*CP*CP*G)-3'), DNA (5'-D(P*CP*GP*GP*AP*TP*AP*AP*GP*GP*GP*CP*TP*GP*AP*GP*CP*AP*CP*GP*CP*CP*GP*A)-3'), DNA (5'-D(P*TP*CP*GP*GP*CP*GP*TP*GP*CP*TP*C)-3'), ... | Authors: | Duckworth, A.T, Ducos, P.L, McMillan, S.D, Satyshur, K.A, Blumenthal, K.H, Deorio, H.R, Larson, J.A, Sandler, S.J, Grant, T, Keck, J.L. | Deposit date: | 2022-11-28 | Release date: | 2023-05-10 | Last modified: | 2023-05-24 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Replication fork binding triggers structural changes in the PriA helicase that govern DNA replication restart in E. coli. Nat Commun, 14, 2023
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