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PDB: 46 results

5DQO
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BU of 5dqo by Molmil
Crystal structure of Y347F mutant of human primase p58 iron-sulfur cluster domain
Descriptor: DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Salay, L.E, Thompson, M.K, Chazin, W.J.
Deposit date:2015-09-15
Release date:2016-09-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport.
Science, 355, 2017
6XQ6
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BU of 6xq6 by Molmil
Receptor for Advanced Glycation End Products VC1 domain in complex with Fragment 11
Descriptor: 3-phenoxyphenol, ACETATE ION, Advanced glycosylation end product-specific receptor, ...
Authors:Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
Deposit date:2020-07-09
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
6XQ3
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BU of 6xq3 by Molmil
Receptor for Advanced Glycation End Products VC1 domain in complex with 3-(3-(((3-(4-Carboxyphenoxy)benzyl)oxy)methyl)phenyl)-1H-indole-2-carboxylic acid
Descriptor: 3-(3-{[3-(4-carboxyphenoxy)phenyl]methoxy}phenyl)-1H-indole-2-carboxylic acid, ACETATE ION, Advanced glycosylation end product-specific receptor, ...
Authors:Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
Deposit date:2020-07-09
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
6XQ8
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BU of 6xq8 by Molmil
Receptor for Advanced Glycation End Products VC1 domain in complex with Fragments 1 & 11
Descriptor: 3-phenoxyphenol, 7-methyl-3-phenyl-1H-indole-2-carboxylic acid, ACETATE ION, ...
Authors:Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
Deposit date:2020-07-09
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
6XQ5
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BU of 6xq5 by Molmil
Receptor for Advanced Glycation End Products VC1 domain in complex with Fragment 1
Descriptor: 7-methyl-3-phenyl-1H-indole-2-carboxylic acid, ACETATE ION, Advanced glycosylation end product-specific receptor, ...
Authors:Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
Deposit date:2020-07-09
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
6XQ7
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BU of 6xq7 by Molmil
Receptor for Advanced Glycation End Products VC1 domain in complex with Fragment 5
Descriptor: 5-bromo-3-methyl-1H-indole-2-carboxylic acid, ACETATE ION, Advanced glycosylation end product-specific receptor, ...
Authors:Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
Deposit date:2020-07-09
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
6XQ9
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BU of 6xq9 by Molmil
Receptor for Advanced Glycation End Products VC1 domain in complex with Fragments 1 & 13
Descriptor: 4-(3-hydroxyphenoxy)benzoic acid, 7-methyl-3-phenyl-1H-indole-2-carboxylic acid, ACETATE ION, ...
Authors:Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
Deposit date:2020-07-09
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
6XQ1
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BU of 6xq1 by Molmil
Receptor for Advanced Glycation End Products VC1 domain in complex with 3-(3-((4-(4-carboxyphenoxy)benzyl)oxy)phenyl)-1H-indole-2-carboxylic acid
Descriptor: 3-[3-({[3-(4-carboxyphenoxy)phenyl]methoxy}methyl)phenyl]-1H-indole-2-carboxylic acid, ACETATE ION, Advanced glycosylation end product-specific receptor, ...
Authors:Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
Deposit date:2020-07-09
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
8U5P
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BU of 8u5p by Molmil
Structure of Mango II aptamer bound to T01-6A-B
Descriptor: 3-[2,16-dioxo-20-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-6,9,12-trioxa-3,15-diazaicosan-1-yl]-2-{(E)-[6-(4-methoxyphenyl)-1-methylquinolin-4(1H)-ylidene]methyl}-1,3-benzothiazol-3-ium, Mango II, POTASSIUM ION
Authors:Passalacqua, L.F.M, Ferre-D'Amare, A.R.
Deposit date:2023-09-12
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of Mango II aptamer bound to T01-6A-B
To Be Published
8U5R
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BU of 8u5r by Molmil
Structure of Mango II variant aptamer bound to T01-6A
Descriptor: Mango II variant, POTASSIUM ION, SODIUM ION
Authors:Passalacqua, L.F.M, Ferre-D'Amare, A.R.
Deposit date:2023-09-12
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Mango II variant aptamer bound to T01-6A
To Be Published
8U60
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BU of 8u60 by Molmil
Structure of Mango II variant2 aptamer bound to T01-6A
Descriptor: 2-[(~{E})-[6-(4-methoxyphenyl)-1-methyl-quinolin-4-ylidene]methyl]-3-methyl-1,3-benzothiazole, POTASSIUM ION, RNA Mango II variant 2 aptamer
Authors:Passalacqua, L.F.M, Ferre-D'Amare, A.R.
Deposit date:2023-09-13
Release date:2024-03-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of Mango II variant2 aptamer bound to T01-6A
To Be Published
8U5T
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BU of 8u5t by Molmil
Structure of Mango II variant aptamer bound to T01-6A-B
Descriptor: 3-{2,16-dioxo-20-[(3aS,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-6,9,12-trioxa-3,15-diazaicosan-1-yl}-2-{(E)-[6-(4-methoxyphenyl)-1-methylquinolin-4(1H)-ylidene]methyl}-1,3-benzothiazol-3-ium, Mango II variant, POTASSIUM ION, ...
Authors:Passalacqua, L.F.M, Ferre-D'Amare, A.R.
Deposit date:2023-09-12
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Mango II variant aptamer bound to T01-6A-B
To Be Published
8U5K
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BU of 8u5k by Molmil
Structure of Mango II aptamer bound to T01-6A
Descriptor: 2-[(~{E})-[6-(4-methoxyphenyl)-1-methyl-quinolin-4-ylidene]methyl]-3-methyl-1,3-benzothiazole, Mango II, POTASSIUM ION
Authors:Passalacqua, L.F.M, Ferre-D'Amare, A.R.
Deposit date:2023-09-12
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Mango II aptamer bound to T01-6A
To Be Published
8U5Z
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BU of 8u5z by Molmil
Structure of Mango II variant aptamer bound to T01-7M-B
Descriptor: 2-[(E)-(1,7-dimethylquinolin-4(1H)-ylidene)methyl]-3-{2,16-dioxo-20-[(3aR,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-6,9,12-trioxa-3,15-diazaicosan-1-yl}-1,3-benzothiazol-3-ium, Mango II variant, POTASSIUM ION, ...
Authors:Passalacqua, L.F.M, Ferre-D'Amare, A.R.
Deposit date:2023-09-13
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Mango II variant aptamer bound to T01-7M-B
To Be Published
8FI8
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BU of 8fi8 by Molmil
Structure of Lettuce C20T bound to DFAME
Descriptor: Lettuce DNA aptamer, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Passalacqua, L.F.M, Ferre-D'Amare, A.R.
Deposit date:2022-12-15
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Intricate 3D architecture of a DNA mimic of GFP.
Nature, 618, 2023
8FHV
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BU of 8fhv by Molmil
Structure of Lettuce aptamer bound to DFHBI-1T with thallium I ions
Descriptor: (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, Lettuce DNA aptamer, MAGNESIUM ION, ...
Authors:Passalacqua, L.F.M, Ferre-D'Amare, A.R.
Deposit date:2022-12-15
Release date:2023-05-10
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Intricate 3D architecture of a DNA mimic of GFP.
Nature, 618, 2023
8FHZ
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BU of 8fhz by Molmil
Structure of Lettuce aptamer bound to DFHO
Descriptor: (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, Lettuce DNA aptamer, MAGNESIUM ION, ...
Authors:Passalacqua, L.F.M, Ferre-D'Amare, A.R.
Deposit date:2022-12-15
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Intricate 3D architecture of a DNA mimic of GFP.
Nature, 618, 2023
8FI2
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BU of 8fi2 by Molmil
Structure of Lettuce C20T bound to DFHBI-1T
Descriptor: (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, Lettuce DNA aptamer, MAGNESIUM ION, ...
Authors:Passalacqua, L.F.M, Ferre-D'Amare, A.R.
Deposit date:2022-12-15
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Intricate 3D architecture of a DNA mimic of GFP.
Nature, 618, 2023
8FI1
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BU of 8fi1 by Molmil
Structure of Lettuce C20G bound to DFHO
Descriptor: (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, Lettuce DNA aptamer, MAGNESIUM ION, ...
Authors:Passalacqua, L.F.M, Ferre-D'Amare, A.R.
Deposit date:2022-12-15
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Intricate 3D architecture of a DNA mimic of GFP.
Nature, 618, 2023
8FI0
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BU of 8fi0 by Molmil
Structure of Lettuce aptamer bound to DFAME
Descriptor: Lettuce DNA aptamer, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Passalacqua, L.F.M, Ferre-D'Amare, A.R.
Deposit date:2022-12-15
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Intricate 3D architecture of a DNA mimic of GFP.
Nature, 618, 2023
8FI7
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BU of 8fi7 by Molmil
Structure of Lettuce C20T bound to DFHO
Descriptor: (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, Lettuce DNA aptamer, MAGNESIUM ION, ...
Authors:Passalacqua, L.F.M, Ferre-D'Amare, A.R.
Deposit date:2022-12-15
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Intricate 3D architecture of a DNA mimic of GFP.
Nature, 618, 2023
8FHX
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BU of 8fhx by Molmil
Structure of Lettuce aptamer bound to DFHBI-1T
Descriptor: (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, Lettuce DNA aptamer, MAGNESIUM ION, ...
Authors:Passalacqua, L.F.M, Ferre-D'Amare, A.R.
Deposit date:2022-12-15
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Intricate 3D architecture of a DNA mimic of GFP.
Nature, 618, 2023
6DI6
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BU of 6di6 by Molmil
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Salay, L.E, Chazin, W.J.
Deposit date:2018-05-22
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DTV
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BU of 6dtv by Molmil
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain Y395F mutant
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Salay, L.E, Chazin, W.J.
Deposit date:2018-06-18
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DI2
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BU of 6di2 by Molmil
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain Y397L mutant
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Salay, L.E, Chazin, W.J.
Deposit date:2018-05-22
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

 

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