6XQ8

Receptor for Advanced Glycation End Products VC1 domain in complex with Fragments 1 & 11

Summary for 6XQ8

• Entry DOI: 10.2210/pdb6xq8/pdb
• Related: 6XQ1 6XQ3 6XQ5 6XQ6 6XQ7
• Descriptor: Advanced glycosylation end product-specific receptor, ACETATE ION, 7-methyl-3-phenyl-1H-indole-2-carboxylic acid, ... (6 entities in total)
• Functional Keywords: rage, ig-like domain, receptor, advanced glycation end products, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 47749.34

Authors

Salay, L.E.,Kozlyuk, N.,Gilston, B.A.,Gogliotti, R.D.,Christov, P.P.,Kim, K.,Ovee, M.,Waterson, A.G.,Chazin, W.J. (deposition date: 2020-07-09, release date: 2021-07-14, Last modification date: 2023-10-18)

• Primary citation: Kozlyuk, N.,Gilston, B.A.,Salay, L.E.,Gogliotti, R.D.,Christov, P.P.,Kim, K.,Ovee, M.,Waterson, A.G.,Chazin, W.J.; A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.; Proteins, 89:1399-1412, 2021; PubMed: 34156100; DOI: 10.1002/prot.26162

Experimental method

X-RAY DIFFRACTION (1.82 Å)