6XQ1
Receptor for Advanced Glycation End Products VC1 domain in complex with 3-(3-((4-(4-carboxyphenoxy)benzyl)oxy)phenyl)-1H-indole-2-carboxylic acid
Summary for 6XQ1
Entry DOI | 10.2210/pdb6xq1/pdb |
Descriptor | Advanced glycosylation end product-specific receptor, ACETATE ION, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | rage, inhibitor, receptor, advanced glycation end products, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 47734.22 |
Authors | Salay, L.E.,Kozlyuk, N.,Gilston, B.A.,Gogliotti, R.D.,Christov, P.P.,Kim, K.,Ovee, M.,Waterson, A.G.,Chazin, W.J. (deposition date: 2020-07-09, release date: 2021-07-14, Last modification date: 2023-10-18) |
Primary citation | Kozlyuk, N.,Gilston, B.A.,Salay, L.E.,Gogliotti, R.D.,Christov, P.P.,Kim, K.,Ovee, M.,Waterson, A.G.,Chazin, W.J. A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors. Proteins, 89:1399-1412, 2021 Cited by PubMed: 34156100DOI: 10.1002/prot.26162 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.51 Å) |
Structure validation
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