4CET
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![BU of 4cet by Molmil](/molmil-images/mine/4cet) | Crystal structure of the complex of the P187S variant of human NAD(P) H:quinone oxidoreductase with dicoumarol at 2.2 A resolution | Descriptor: | BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE], FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1 | Authors: | Lienhart, W.D, Gudipati, V, Uhl, M.K, Binter, A, Pulido, S, Saf, R, Zangger, K, Gruber, K, Macheroux, P. | Deposit date: | 2013-11-12 | Release date: | 2014-08-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Collapse of the Native Structure by a Single Amino Acid Exchange in Human Nad(P)H:Quinone Oxidoreductase (Nqo1). FEBS J., 281, 2014
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4CF6
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![BU of 4cf6 by Molmil](/molmil-images/mine/4cf6) | Crystal structure of the complex of the P187S variant of human NAD(P) H:quinone oxidoreductase with Cibacron blue at 2.7 A resolution | Descriptor: | CIBACRON BLUE, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1 | Authors: | Lienhart, W.D, Gudipati, V, Uhl, M.K, Binter, A, Pulido, S, Saf, R, Zangger, K, Gruber, K, Macheroux, P. | Deposit date: | 2013-11-13 | Release date: | 2014-08-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.694 Å) | Cite: | Collapse of the Native Structure by a Single Amino Acid Exchange in Human Nad(P)H:Quinone Oxidoreductase (Nqo1). FEBS J., 281, 2014
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3UGU
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![BU of 3ugu by Molmil](/molmil-images/mine/3ugu) | |
7R4S
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![BU of 7r4s by Molmil](/molmil-images/mine/7r4s) | |
7R56
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![BU of 7r56 by Molmil](/molmil-images/mine/7r56) | |
7R5N
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4ZRG
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![BU of 4zrg by Molmil](/molmil-images/mine/4zrg) | Visual arrestin mutant - R175E | Descriptor: | CARBON DIOXIDE, S-arrestin | Authors: | Granzin, J, Stadler, A, Cousin, A, Schlesinger, R, Batra-Safferling, R. | Deposit date: | 2015-05-12 | Release date: | 2015-11-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural evidence for the role of polar core residue Arg175 in arrestin activation. Sci Rep, 5, 2015
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5J4E
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5J3W
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6I8W
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![BU of 6i8w by Molmil](/molmil-images/mine/6i8w) | Crystal structure of a membrane phospholipase A, a novel bacterial virulence factor | Descriptor: | Alpha/beta fold hydrolase, CARBON DIOXIDE, ISOPROPYL ALCOHOL, ... | Authors: | Granzin, J, Batra-Safferling, R. | Deposit date: | 2018-11-21 | Release date: | 2019-11-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural, mechanistic, and physiological insights into phospholipase A-mediated membrane phospholipid degradation in Pseudomonas aeruginosa. Elife, 11, 2022
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6BWU
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![BU of 6bwu by Molmil](/molmil-images/mine/6bwu) | Crystal structure of carboxyhemoglobin in complex with beta Cys93 modifying agent, TD3 | Descriptor: | 1H-1,2,3-triazole-5-thiol, CARBON MONOXIDE, Hemoglobin subunit alpha, ... | Authors: | Musayev, F.N, Safo, R.M, Safo, M.K. | Deposit date: | 2017-12-15 | Release date: | 2018-01-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells. Mol. Pharm., 15, 2018
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6BWP
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![BU of 6bwp by Molmil](/molmil-images/mine/6bwp) | Crystal structure of Deoxy Hemoglobin in complex with beta Cys93 modifying agent, TD3 | Descriptor: | 1H-1,2,3-triazole-5-thiol, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | Authors: | Musayev, F.N, Safo, R.M, Safo, M.K. | Deposit date: | 2017-12-15 | Release date: | 2018-01-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells. Mol. Pharm., 15, 2018
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7ABY
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![BU of 7aby by Molmil](/molmil-images/mine/7aby) | Crystal structure of iLOV-Q489K mutant | Descriptor: | ACETATE ION, FLAVIN MONONUCLEOTIDE, Phototropin-2 | Authors: | Granzin, J, Batra-Safferling, R. | Deposit date: | 2020-09-09 | Release date: | 2021-04-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The molecular basis of spectral tuning in blue- and red-shifted flavin-binding fluorescent proteins. J.Biol.Chem., 296, 2021
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7A6P
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3UGX
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![BU of 3ugx by Molmil](/molmil-images/mine/3ugx) | Crystal Structure of Visual Arrestin | Descriptor: | 1,2-ETHANEDIOL, IMIDAZOLE, PENTANEDIAL, ... | Authors: | Batra-Safferling, R, Granzin, J. | Deposit date: | 2011-11-03 | Release date: | 2012-02-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.649 Å) | Cite: | Crystal Structure of p44, a Constitutively Active Splice Variant of Visual Arrestin. J.Mol.Biol., 416, 2012
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3R5I
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![BU of 3r5i by Molmil](/molmil-images/mine/3r5i) | Crystal structure of liganded Hemoglobin complexed with a potent Antisickling agent, INN-312 | Descriptor: | 5-methoxy-2-(pyridin-3-ylmethoxy)benzaldehyde, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | Authors: | Safo, M.K, Musayev, F.N, Safo, R.P, Daniels, D, Eseonu, D.N, Parra, J. | Deposit date: | 2011-03-18 | Release date: | 2011-04-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and in Vitro Chracterization of Pyridyl Derivatives of Benzaldehydes : Highly Potent Antisickling Agents To be Published
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4JGG
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![BU of 4jgg by Molmil](/molmil-images/mine/4jgg) | |
5LTL
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5LUV
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7YX0
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![BU of 7yx0 by Molmil](/molmil-images/mine/7yx0) | Crystal structure of the full-length short LOV protein SBW25-LOV from Pseudomonas fluorescens (light state) | Descriptor: | ACETATE ION, FLAVIN MONONUCLEOTIDE, Flavin mononucleotide (semi-quinone intermediate), ... | Authors: | Arinkin, V, Batra-Safferling, R, Granzin, J. | Deposit date: | 2022-02-15 | Release date: | 2023-05-24 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Conserved Signal Transduction Mechanisms and Dark Recovery Kinetic Tuning in the Pseudomonadaceae Short Light, Oxygen, Voltage (LOV) Protein Family. J.Mol.Biol., 2024
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7ZQU
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8A36
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![BU of 8a36 by Molmil](/molmil-images/mine/8a36) | |
8A33
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8A37
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8A3U
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![BU of 8a3u by Molmil](/molmil-images/mine/8a3u) | Crystal structure of a chimeric LOV-Histidine kinase SB2F1 (symmetrical variant, trigonal form with short c-axis) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, FLAVIN MONONUCLEOTIDE, Putative Sensory box protein,Sensor protein FixL | Authors: | Arinkin, V, Batra-Safferling, R, Granzin, J. | Deposit date: | 2022-06-09 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Crystal structure of a chimeric LOV-Histidine kinase SB2F1 (symmetrical variant, trigonal form
with short c-axis) To Be Published
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