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PDB: 369 results

1Y51
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X-ray crystal structure of Bacillus stearothermophilus Histidine phosphocarrier protein (Hpr) F29W mutant
Descriptor: Phosphocarrier protein HPr, SULFATE ION
Authors:Sridharan, S, Razvi, A, Scholtz, J.M, Sacchettini, J.C.
Deposit date:2004-12-01
Release date:2005-02-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The HPr proteins from the thermophile Bacillus stearothermophilus can form domain-swapped dimers.
J.Mol.Biol., 346, 2005
1YNV
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BU of 1ynv by Molmil
Asp79 makes a large, unfavorable contribution to the stability of RNase Sa
Descriptor: Guanyl-specific ribonuclease Sa, SULFATE ION
Authors:Trevino, S.R, Gokulan, K, Newsom, S, Thurlkill, R.L, Shaw, K.L, Mitkevich, V.A, Makarov, A.A, Sacchettini, J.C, Scholtz, J.M, Pace, C.N.
Deposit date:2005-01-25
Release date:2005-07-19
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Asp79 Makes a Large, Unfavorable Contribution to the Stability of RNase Sa.
J.Mol.Biol., 354, 2005
1YNL
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BU of 1ynl by Molmil
Identification of Key residues of the NC6.8 Fab antibody fragment binding to synthetic sweeterners: Crystal structure of NC6.8 co-crystalized with high potency sweetener compound SC45647
Descriptor: 2-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-ETHANESULFONIC ACID, Ig gamma heavy chain, Ig gamma light chain
Authors:Gokulan, K, Khare, S, Ronning, D.R, Linthicum, S.D, Sacchettini, J.C, Rupp, B.
Deposit date:2005-01-24
Release date:2005-08-16
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Cocrystal Structures of NC6.8 Fab Identify Key Interactions for High Potency Sweetener Recognition: Implications for the Design of Synthetic Sweeteners
Biochemistry, 44, 2005
1DIH
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BU of 1dih by Molmil
THREE-DIMENSIONAL STRUCTURE OF E. COLI DIHYDRODIPICOLINATE REDUCTASE
Descriptor: DIHYDRODIPICOLINATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Scapin, G, Blanchard, J.S, Sacchettini, J.C.
Deposit date:1994-09-14
Release date:1995-09-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase.
Biochemistry, 34, 1995
1ZXX
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BU of 1zxx by Molmil
The crystal structure of phosphofructokinase from Lactobacillus delbrueckii
Descriptor: 6-phosphofructokinase, SULFATE ION
Authors:Paricharttanakul, N.M, Ye, S, Menefee, A.L, Javid-Majd, F, Sacchettini, J.C, Reinhart, G.D.
Deposit date:2005-06-09
Release date:2005-11-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Kinetic and Structural Characterization of Phosphofructokinase from Lactobacillus bulgaricus.
Biochemistry, 44, 2005
4ISB
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BU of 4isb by Molmil
Crystal Structure of Apo Mtb FadD10
Descriptor: Long chain fatty acid CoA ligase FadD10, SULFATE ION
Authors:Liu, Z, Wang, F, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2013-01-16
Release date:2013-05-08
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of Mycobacterium tuberculosis FadD10 protein reveal a new type of adenylate-forming enzyme.
J.Biol.Chem., 288, 2013
1UCL
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BU of 1ucl by Molmil
Mutants of RNase Sa
Descriptor: Guanyl-specific ribonuclease Sa, SULFATE ION
Authors:Takano, K, Scholtz, J.M, Sacchettini, J.C, Pace, C.N.
Deposit date:2003-04-15
Release date:2003-09-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:The contribution of polar group burial to protein stability is strongly context-dependent
J.Biol.Chem., 278, 2003
4JAQ
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BU of 4jaq by Molmil
Crystal Structure of Mycobacterium tuberculosis PKS11 Reveals Intermediates in the Synthesis of Methyl-branched Alkylpyrones
Descriptor: 3,5-dioxoicosanoic acid, Alpha-pyrone synthesis polyketide synthase-like Pks11, COENZYME A, ...
Authors:Gokulan, K, Sacchettini, J.C, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
Deposit date:2013-02-19
Release date:2013-04-24
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones.
J.Biol.Chem., 288, 2013
4JD3
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BU of 4jd3 by Molmil
Crystal Structure of Mycobacterium tuberculosis PKS11 Reveals Intermediates in the Synthesis of Methyl-branched Alkylpyrones
Descriptor: Alpha-pyrone synthesis polyketide synthase-like Pks11, COENZYME A, PALMITIC ACID
Authors:Gokulan, K, Sacchettini, J.C, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
Deposit date:2013-02-22
Release date:2013-04-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones.
J.Biol.Chem., 288, 2013
5V3W
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BU of 5v3w by Molmil
Crystal Structure of the Apo form of Thioesterase domain of Mtb Pks13
Descriptor: (2R)-2-{[(2R)-2-{[(2S)-2-{[(2R)-2-hydroxypropyl]oxy}propyl]oxy}propyl]oxy}propan-1-ol, Polyketide synthase Pks13 (Termination polyketide synthase)
Authors:Aggarwal, A, Sacchettini, J.C.
Deposit date:2017-03-08
Release date:2017-07-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.723 Å)
Cite:Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.
Cell, 170, 2017
5V40
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BU of 5v40 by Molmil
Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor TAM6
Descriptor: Polyketide synthase Pks13 (Termination polyketide synthase), ethyl 4-[(dimethylamino)methyl]-5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate
Authors:Aggarwal, A, Sacchettini, J.C.
Deposit date:2017-03-08
Release date:2017-07-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.991 Å)
Cite:Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.
Cell, 170, 2017
1R1V
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BU of 1r1v by Molmil
Crystal structure of the metal-sensing transcriptional repressor CzrA from Staphylococcus aureus in the Zn2-form
Descriptor: ZINC ION, repressor protein
Authors:Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P.
Deposit date:2003-09-25
Release date:2004-05-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
1R22
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BU of 1r22 by Molmil
Crystal structure of the cyanobacterial metallothionein repressor SmtB (C14S/C61S/C121S mutant) in the Zn2alpha5-form
Descriptor: Transcriptional repressor smtB, ZINC ION
Authors:Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P.
Deposit date:2003-09-25
Release date:2004-05-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
1R1U
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BU of 1r1u by Molmil
Crystal structure of the metal-sensing transcriptional repressor CzrA from Staphylococcus aureus in the apo-form
Descriptor: repressor protein
Authors:Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P.
Deposit date:2003-09-25
Release date:2004-05-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
1R23
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BU of 1r23 by Molmil
Crystal structure of the cyanobacterial metallothionein repressor SmtB in the Zn1-form (one Zn(II) per dimer)
Descriptor: Transcriptional repressor smtB, ZINC ION
Authors:Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P.
Deposit date:2003-09-25
Release date:2004-05-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
1R8J
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BU of 1r8j by Molmil
Crystal Structure of Circadian Clock Protein KaiA from Synechococcus elongatus
Descriptor: KaiA
Authors:Ye, S, Vakonakis, I, Sacchettini, J.C, LiWang, A.C.
Deposit date:2003-10-26
Release date:2004-06-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystal structure of circadian clock protein KaiA from Synechococcus elongatus
J.Biol.Chem., 279, 2004
4IR7
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BU of 4ir7 by Molmil
Crystal Structure of Mtb FadD10 in Complex with Dodecanoyl-AMP
Descriptor: 5'-O-[(S)-(dodecanoyloxy)(hydroxy)phosphoryl]adenosine, Long chain fatty acid CoA ligase FadD10, MAGNESIUM ION
Authors:Liu, Z, Wang, F, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2013-01-14
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of Mycobacterium tuberculosis FadD10 protein reveal a new type of adenylate-forming enzyme.
J.Biol.Chem., 288, 2013
1SFR
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BU of 1sfr by Molmil
Crystal Structure of the Mycobacterium tuberculosis Antigen 85A Protein
Descriptor: Antigen 85-A
Authors:Ronning, D.R, Vissa, V, Besra, G.S, Belisle, J.T, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-02-20
Release date:2004-07-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mycobacterium tuberculosis Antigen 85A and 85C Structures Confirm Binding Orientation and Conserved Substrate Specificity
J.Biol.Chem., 279, 2004
1UCI
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BU of 1uci by Molmil
Mutants of RNase Sa
Descriptor: Guanyl-specific ribonuclease Sa, SULFATE ION
Authors:Takano, K, Scholtz, J.M, Sacchettini, J.C, Pace, C.N.
Deposit date:2003-04-15
Release date:2003-09-09
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The contribution of polar group burial to protein stability is strongly context-dependent
J.Biol.Chem., 278, 2003
5V42
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BU of 5v42 by Molmil
Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor TAM3
Descriptor: Polyketide synthase Pks13 (Termination polyketide synthase), ethyl 5-hydroxy-2-phenyl-4-(pyrrolidin-1-ylmethyl)-1-benzofuran-3-carboxylate
Authors:Aggarwal, A, Sacchettini, J.C.
Deposit date:2017-03-08
Release date:2017-07-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.987 Å)
Cite:Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.
Cell, 170, 2017
5V3Y
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BU of 5v3y by Molmil
Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor TAM16
Descriptor: 2-(4-hydroxyphenyl)-~{N}-methyl-5-oxidanyl-4-(piperidin-1-ylmethyl)-1-benzofuran-3-carboxamide, Polyketide synthase Pks13 (Termination polyketide synthase), SULFATE ION
Authors:Aggarwal, A, Sacchettini, J.C.
Deposit date:2017-03-08
Release date:2017-07-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.
Cell, 170, 2017
1R1T
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BU of 1r1t by Molmil
Crystal structure of the cyanobacterial metallothionein repressor SmtB in the apo-form
Descriptor: Transcriptional repressor smtB
Authors:Eicken, C, Pennella, M.A, Chen, X, Koshlap, K.M, VanZile, M.L, Sacchettini, J.C, Giedroc, D.P.
Deposit date:2003-09-25
Release date:2004-05-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
J.Mol.Biol., 333, 2003
5V41
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BU of 5v41 by Molmil
Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor TAM5
Descriptor: Polyketide synthase Pks13 (Termination polyketide synthase), ethyl 5-hydroxy-4-(morpholin-4-ylmethyl)-2-phenyl-1-benzofuran-3-carboxylate
Authors:Aggarwal, A, Sacchettini, J.C.
Deposit date:2017-03-08
Release date:2017-07-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.051 Å)
Cite:Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.
Cell, 170, 2017
4KBJ
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BU of 4kbj by Molmil
Structure of Mtb RNAP Beta subunit B1 and B2 domains
Descriptor: DNA-directed RNA polymerase subunit beta
Authors:Gulten, G, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2013-04-23
Release date:2013-10-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4532 Å)
Cite:Structure of the Mtb CarD/RNAP beta-Lobes Complex Reveals the Molecular Basis of Interaction and Presents a Distinct DNA-Binding Domain for Mtb CarD.
Structure, 21, 2013
5V3Z
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BU of 5v3z by Molmil
Crystal Structure of the D1607N mutant form of Thioesterase domain of Mtb Pks13
Descriptor: PENTAETHYLENE GLYCOL, Polyketide synthase Pks13 (Termination polyketide synthase), SULFATE ION
Authors:Aggarwal, A, Sacchettini, J.C.
Deposit date:2017-03-08
Release date:2017-07-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.881 Å)
Cite:Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.
Cell, 170, 2017

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