2I7K
 
 | | Solution Structure of the Bromodomain of Human BRD7 Protein | | 分子名称: | Bromodomain-containing protein 7 | | 著者 | Sun, H, Liu, J, Zhang, J, Huang, H, Wu, J, Shi, Y. | | 登録日 | 2006-08-31 | | 公開日 | 2007-07-10 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of BRD7 bromodomain and its interaction with acetylated peptides from histone H3 and H4
Biochem.Biophys.Res.Commun., 358, 2007
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4XPJ
 | | Crystal structure of Nerve growth factor in complex with lysophosphatidylinositol | | 分子名称: | (2R)-2-hydroxy-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl tridecanoate, Beta-nerve growth factor | | 著者 | Sun, H.L, Jiang, T. | | 登録日 | 2015-01-17 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.605 Å) | | 主引用文献 | The structure of nerve growth factor in complex with lysophosphatidylinositol
Acta Crystallogr.,Sect.F, 71, 2015
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1MIF
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5C71
 | | The structure of Aspergillus oryzae a-glucuronidase complexed with glycyrrhetinic acid monoglucuronide | | 分子名称: | (3BETA,5BETA,14BETA)-3-HYDROXY-11-OXOOLEAN-12-EN-29-OIC ACID, Glucuronidase, alpha-D-glucopyranuronic acid | | 著者 | Sun, H.L, Lv, B, Huang, S, Li, C, Jiang, T. | | 登録日 | 2015-06-24 | | 公開日 | 2016-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Structure-guided engineering of the substrate specificity of a fungal beta-glucuronidase toward triterpenoid saponins.
J.Biol.Chem., 293, 2018
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2NZW
 | | Crystal Structure of alpha1,3-Fucosyltransferase | | 分子名称: | Alpha1,3-fucosyltransferase, SULFATE ION | | 著者 | Sun, H.Y, Ko, T.P. | | 登録日 | 2006-11-27 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure and mechanism of Helicobacter pylori fucosyltransferase. A basis for lipopolysaccharide variation and inhibitor design.
J. Biol. Chem., 282, 2007
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2NZY
 | | Crystal Structure of alpha1,3-Fucosyltransferase with GDP-fucose | | 分子名称: | Alpha1,3-Fucosyltransferase, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, ... | | 著者 | Sun, H.Y, Ko, T.P. | | 登録日 | 2006-11-27 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure and mechanism of Helicobacter pylori fucosyltransferase. A basis for lipopolysaccharide variation and inhibitor design.
J. Biol. Chem., 282, 2007
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5WTD
 | | Structure of human serum transferrin bound ruthenium at N-lobe | | 分子名称: | FE (III) ION, MALONATE ION, RUTHENIUM ION, ... | | 著者 | Sun, H, Wang, M, Lai, T.P, Zhang, H, Hao, Q. | | 登録日 | 2016-12-11 | | 公開日 | 2017-12-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake.
J.Inorg.Biochem., 234, 2022
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5X5P
 | | Human serum transferrin bound to ruthenium NTA | | 分子名称: | FE (III) ION, MALONATE ION, NITRILOTRIACETIC ACID, ... | | 著者 | Sun, H, Wang, M. | | 登録日 | 2017-02-17 | | 公開日 | 2018-02-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake.
J.Inorg.Biochem., 234, 2022
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5C70
 | | The structure of Aspergillus oryzae beta-glucuronidase | | 分子名称: | Glucuronidase | | 著者 | Sun, H.L, Lv, B, Huang, S, Sun, Q.F, Li, C, Jiang, T. | | 登録日 | 2015-06-24 | | 公開日 | 2016-06-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Enhancing the Thermostability of beta-Glucuronidase by Rationally Redesigning the Catalytic Domain Based on Sequence Alignment Strategy
Ind Eng Chem Res, 55, 2016
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8IV5
 | | Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 8H12 and 1C4 (local refinement) | | 分子名称: | Spike protein S1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, heavy chain of 1C4, ... | | 著者 | Sun, H, Jiang, Y, Zheng, Q, Li, S, Xia, N. | | 登録日 | 2023-03-26 | | 公開日 | 2023-08-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.77 Å) | | 主引用文献 | Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD.
Protein Cell, 15, 2024
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8IV8
 | | Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 3E2 and 1C4 (local refinement) | | 分子名称: | Spike protein S1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, heavy chain of 1C4, ... | | 著者 | Sun, H, Jiang, Y, Zheng, Q, Li, S, Xia, N. | | 登録日 | 2023-03-26 | | 公開日 | 2023-08-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | | 主引用文献 | Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD.
Protein Cell, 15, 2024
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8IVA
 | | Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs XMA01 and 3E2 (local refinement) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, heavy chain of 3E2, ... | | 著者 | Sun, H, Jiang, Y, Zheng, Q, Li, S, Xia, N. | | 登録日 | 2023-03-26 | | 公開日 | 2023-08-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.95 Å) | | 主引用文献 | Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD.
Protein Cell, 15, 2024
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8IV4
 | | Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 8H12 and 3E2 (local refinement) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, heavy chain of 3E2, ... | | 著者 | Sun, H, Jiang, Y, Zheng, Q, Li, S, Xia, N. | | 登録日 | 2023-03-26 | | 公開日 | 2023-08-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | | 主引用文献 | Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD.
Protein Cell, 15, 2024
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8IX3
 | | Cryo-EM structure of SARS-CoV-2 BA.4/5 spike protein in complex with 1G11 (local refinement) | | 分子名称: | BA.4/5 variant spike protein, heavy chain of 1G11, light chain of 1G11 | | 著者 | Sun, H, Jiang, Y, Zheng, Z, Zheng, Q, Li, S. | | 登録日 | 2023-03-31 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | | 主引用文献 | Structural basis for broad neutralization of human antibody against Omicron sublineages and evasion by XBB variant.
J.Virol., 97, 2023
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2NZX
 | | Crystal Structure of alpha1,3-Fucosyltransferase with GDP | | 分子名称: | Alpha1,3-fucosyltransferase, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION | | 著者 | Sun, H.Y, Ko, T.P. | | 登録日 | 2006-11-27 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure and mechanism of Helicobacter pylori fucosyltransferase. A basis for lipopolysaccharide variation and inhibitor design.
J. Biol. Chem., 282, 2007
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2AZK
 | | Crystal structure for the mutant W136E of Sulfolobus solfataricus hexaprenyl pyrophosphate synthase | | 分子名称: | Geranylgeranyl pyrophosphate synthetase | | 著者 | Sun, H.Y, Ko, T.P, Kuo, C.J, Guo, R.T, Chou, C.C, Liang, P.H, Wang, A.H.J. | | 登録日 | 2005-09-12 | | 公開日 | 2006-03-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures
J.Bacteriol., 187, 2005
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2AZL
 | | Crystal structure for the mutant F117E of Thermotoga maritima octaprenyl pyrophosphate synthase | | 分子名称: | octoprenyl-diphosphate synthase | | 著者 | Sun, H.Y, Ko, T.P, Kuo, C.J, Guo, R.T, Chou, C.C, Liang, P.H, Wang, A.H. | | 登録日 | 2005-09-12 | | 公開日 | 2006-03-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures
J.Bacteriol., 187, 2005
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2AZJ
 | | Crystal structure for the mutant D81C of Sulfolobus solfataricus hexaprenyl pyrophosphate synthase | | 分子名称: | Geranylgeranyl pyrophosphate synthetase | | 著者 | Sun, H.Y, Ko, T.P, Kuo, C.J, Guo, R.T, Chou, C.C, Liang, P.H, Wang, A.H.J. | | 登録日 | 2005-09-11 | | 公開日 | 2006-03-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures
J.Bacteriol., 187, 2005
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2DK9
 | | Solution structure of Calponin Homology domain of Human MICAL-1 | | 分子名称: | NEDD9-interacting protein with calponin homology and LIM domains | | 著者 | Sun, H, Dai, H, Zhang, J, Xiong, S, Wu, J, Shi, Y. | | 登録日 | 2006-04-07 | | 公開日 | 2006-09-19 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of calponin homology domain of Human MICAL-1
J.Biomol.Nmr, 36, 2006
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8GTA
 | | Cryo-EM structure of the marine siphophage vB_Dshs-R4C capsid | | 分子名称: | Major capsid protein | | 著者 | Sun, H, Huang, Y, Zheng, Q, Li, S, Zhang, R, Xia, N. | | 登録日 | 2022-09-07 | | 公開日 | 2023-07-12 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | | 主引用文献 | Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
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7DEA
 | | Structure of an avian influenza H5 hemagglutinin from the influenza virus A/duck Northern China/22/2017 (H5N6) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | | 著者 | Sun, H, Sun, H, Song, J, Zhang, W, Wei, X, Qi, J, Gao, G.F, Liu, J. | | 登録日 | 2020-11-03 | | 公開日 | 2021-11-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Haemagglutinin and neuraminidase acid stability in H5N6 avian influenza virus confers infection adaptation in mammals
To Be Published
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7DEB
 | | Structure of an avian influenza H5 hemagglutinin from the influenza virus A/duck/Eastern China/L0230/2010 (H5N2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Sun, H, Sun, H, Song, J, Zhang, W, Qi, J, Gao, G.F, Liu, J. | | 登録日 | 2020-11-03 | | 公開日 | 2021-11-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Haemagglutinin and neuraminidase acid stability in H5N6 avian influenza virus confers infection adaptation in mammals
To Be Published
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7XH0
 | | crystal structure of Csn-PD from Paenibacillus dendritiformis | | 分子名称: | 1,2-ETHANEDIOL, CITRATE ANION, Chitosanase | | 著者 | Sun, H.H, Cheng, Y.M, Cao, R, Liu, Q, Zhao, L. | | 登録日 | 2022-04-07 | | 公開日 | 2022-06-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | crystal structure of Csn-PD from Paenibacillus dendritiformis
To Be Published
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7X7T
 | | Cryo-EM structure of SARS-CoV-2 spike protein in complex with three nAbs X01, X10 and X17 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, X01 heavy chain, ... | | 著者 | Sun, H, Liu, L, Zheng, Q, Li, S, Zhang, T, Xia, N. | | 登録日 | 2022-03-10 | | 公開日 | 2022-08-17 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7X7V
 | | Cryo-EM structure of SARS-CoV spike protein in complex with three nAbs X01, X10 and X17 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, X01 heavy chain, ... | | 著者 | Sun, H, Liu, L, Zhang, T, Zheng, Q, Li, S, Xia, N. | | 登録日 | 2022-03-10 | | 公開日 | 2022-08-17 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.83 Å) | | 主引用文献 | The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 119, 2022
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