6BWZ
 
 | | SYSGYS from low-complexity domain of FUS, residues 37-42 | | 分子名称: | SYSGYS peptide from low-complexity domain of FUS | | 著者 | Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Tamir, G, Eisenberg, D.S. | | 登録日 | 2017-12-15 | | 公開日 | 2018-04-04 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.
Science, 359, 2018
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6C3T
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5TXJ
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5WHN
 | | Crystal structure of the segment, NFGAFS, from the low complexity domain of TDP-43, residues 312-317 | | 分子名称: | Segment of TAR DNA-binding protein 43 | | 著者 | Guenther, E.L, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2017-07-17 | | 公開日 | 2018-04-25 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
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6DJ0
 | | ASLTVS segment from Human Immunoglobulin Light-Chain Variable Domain, Residues 73-78, assembled as an amyloid fibril | | 分子名称: | ASLTVS segment from Light-Chain Variable Domain, Lambda Mcg | | 著者 | Brumshtein, B, Esswein, S.R, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2018-05-24 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis.
J. Biol. Chem., 293, 2018
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6C3S
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7N2L
 | | MicroED structure of a mutant mammalian prion segment | | 分子名称: | prion protein | | 著者 | Flores, M.D, Richards, L.S, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | | 登録日 | 2021-05-29 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (0.9 Å) | | 主引用文献 | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED.
Acs Bio Med Chem Au, 3, 2023
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7N2K
 | | MicroED structure of sequence variant of repeat segment of the yeast prion New1p phased by ARCIMBOLDO-BORGES | | 分子名称: | prion New1p | | 著者 | Flores, M.D, Richards, L.S, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | | 登録日 | 2021-05-29 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.301 Å) | | 主引用文献 | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED.
Acs Bio Med Chem Au, 3, 2023
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7N2H
 | | X-Ray structure of a sequence variant of a repeat segment of the yeast prion New1p | | 分子名称: | prion New1p | | 著者 | Richards, L.S, Flores, M.D, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | | 登録日 | 2021-05-29 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.102 Å) | | 主引用文献 | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED.
Acs Bio Med Chem Au, 3, 2023
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7N2G
 | | MicroED structure of human CPEB3 segment(154-161) kinked polymorph phased by ARCIMBOLDO-BORGES | | 分子名称: | CPEB3 | | 著者 | Flores, M.D, Richards, L.S, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | | 登録日 | 2021-05-29 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.201 Å) | | 主引用文献 | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED.
Acs Bio Med Chem Au, 3, 2023
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7N2J
 | | MicroED structure of a mutant mammalian prion segment phased by ARCIMBOLDO-BORGES | | 分子名称: | prion protein | | 著者 | Richards, L.S, Flores, M.D, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | | 登録日 | 2021-05-29 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.5 Å) | | 主引用文献 | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED.
Acs Bio Med Chem Au, 3, 2023
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7N2F
 | | MicroED structure of human CPEB3 segment (154-161) straight polymorph phased by ARCIMBOLDO-BORGES | | 分子名称: | CPEB3 | | 著者 | Flores, M.D, Richards, L.S, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | | 登録日 | 2021-05-29 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.2 Å) | | 主引用文献 | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED.
Acs Bio Med Chem Au, 3, 2023
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7N2D
 | | MicroED structure of human zinc finger protein 292 segment (534-542) phased by ARCIMBOLDO-BORGES | | 分子名称: | DIMETHYL SULFOXIDE, zinc finger protein 292 | | 著者 | Richards, L.S, Flores, M.D, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | | 登録日 | 2021-05-28 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.503 Å) | | 主引用文献 | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED.
Acs Bio Med Chem Au, 3, 2023
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7N2I
 | | MicroED structure of human LECT2 (45-53) phased by ARCIMBOLDO-BORGES | | 分子名称: | LECT2 | | 著者 | Richards, L.S, Flores, M.D, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | | 登録日 | 2021-05-29 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.402 Å) | | 主引用文献 | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED.
Acs Bio Med Chem Au, 3, 2023
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7N2E
 | | MicroED structure of human CPEB3 segment (154-161) straight polymorph | | 分子名称: | CPEB3 | | 著者 | Flores, M.D, Richards, L.S, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R. | | 登録日 | 2021-05-29 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1 Å) | | 主引用文献 | Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED.
Acs Bio Med Chem Au, 3, 2023
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7M61
 | | Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils seeded by patient extracted fibrils, polymorph 1 | | 分子名称: | Islet amyloid polypeptide | | 著者 | Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2021-03-25 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores
Nat.Struct.Mol.Biol., 28, 2021
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7M64
 | | Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils seeded by patient extracted fibrils, polymorph 3 | | 分子名称: | Islet amyloid polypeptide | | 著者 | Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2021-03-25 | | 公開日 | 2021-09-22 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores
Nat.Struct.Mol.Biol., 28, 2021
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3IA0
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6E75
 | | Structure of Human Transthyretin Asp38Ala Mutant | | 分子名称: | ACETATE ION, Transthyretin | | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. | | 登録日 | 2018-07-25 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural Variants of Transthyretin
To Be Published
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5UBO
 | | Mical-oxidized Actin complex with Gelsolin Segment 1 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | 著者 | Grintsevich, E.E, Sawaya, M.R, Reisler, E. | | 登録日 | 2016-12-21 | | 公開日 | 2017-12-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Catastrophic disassembly of actin filaments via Mical-mediated oxidation.
Nat Commun, 8, 2017
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3I96
 | | Ethanolamine Utilization Microcompartment Shell Subunit, EutS | | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CHLORIDE ION, Ethanolamine utilization protein eutS, ... | | 著者 | Tanaka, S, Sawaya, M.R, Yeates, T.O. | | 登録日 | 2009-07-10 | | 公開日 | 2010-01-12 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure and Mechanisms of a Protein-Based Organelle in Escherichia coli.
Science, 327, 2010
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6E6Z
 | | Structure of Wild Type Human Transthyretin in Complex with Tafamidis | | 分子名称: | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin | | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. | | 登録日 | 2018-07-25 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural Variants of Transthyretin
To Be Published
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6E77
 | | Structure of Human Transthyretin Asp38Ala Mutant in Complex with Tafamidis | | 分子名称: | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin | | 著者 | Saelices, L, Chung, K, Sawaya, M.R, Cascio, D, Eisenberg, D. | | 登録日 | 2018-07-25 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural Variants of Transthyretin
To Be Published
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6BXV
 | | SYSSYGQS from low-complexity domain of FUS, residues 54-61 | | 分子名称: | FUS | | 著者 | Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Gonen, T, Eisenberg, D.S. | | 登録日 | 2017-12-19 | | 公開日 | 2018-04-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.
Science, 359, 2018
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5W50
 | | Crystal structure of the segment, LIIKGI, from the RRM2 of TDP-43, residues 248-253 | | 分子名称: | TAR DNA-binding protein 43 | | 著者 | Guenther, E.L, Trinh, H, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2017-06-13 | | 公開日 | 2018-02-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2.
Nat. Struct. Mol. Biol., 25, 2018
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