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PDB: 611 件

1JG2
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Crystal Structure of L-isoaspartyl (D-aspartyl) O-methyltransferase with adenosine
分子名称: ADENOSINE, SODIUM ION, protein-L-isoaspartate O-methyltransferase
著者Griffith, S.C, Sawaya, M.R, Boutz, D, Thapar, N, Katz, J, Clarke, S, Yeates, T.O.
登録日2001-06-22
公開日2001-11-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of a protein repair methyltransferase from Pyrococcus furiosus with its L-isoaspartyl peptide substrate.
J.Mol.Biol., 313, 2001
1JRK
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Crystal Structure of a Nudix Protein from Pyrobaculum aerophilum Reveals a Dimer with Intertwined Beta Sheets
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Nudix homolog
著者Wang, S, Mura, C, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2001-08-13
公開日2002-04-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of a Nudix protein from Pyrobaculum aerophilum reveals a dimer with two intersubunit beta-sheets.
Acta Crystallogr.,Sect.D, 58, 2002
6C3F
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AMYLOID FORMING PEPTIDE IYKVEI FROM TRANSTHYRETIN
分子名称: ILE-TYR-LYS-VAL-GLU-ILE, trifluoroacetic acid
著者Saelices, L, Sawaya, M.R, Eisenberg, D.S.
登録日2018-01-09
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.499 Å)
主引用文献Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
6C88
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STRUCTURE OF THE AMYLOID FORMING PEPTIDE VAVHVF FROM TRANSTHYRETIN
分子名称: GLYCEROL, VAL-ALA-VAL-HIS-VAL-PHE
著者Saelices, L, Sawaya, M.R, Eisenberg, D.S.
登録日2018-01-24
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
6C3G
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AMYLOID FORMING PEPTIDE KALGIS FROM TRANSTHYRETIN
分子名称: GLYCEROL, LYS-ALA-LEU-GLY-ILE-SER, SULFATE ION
著者Saelices, L, Sawaya, M.R, Eisenberg, D.S.
登録日2018-01-09
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
4M5T
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Disulfide trapped human alphaB crystallin core domain in complex with C-terminal peptide
分子名称: Alpha-crystallin B chain, SULFATE ION
著者Laganowsky, A, Cascio, D, Hochberg, G, Sawaya, M.R, Benesch, J.L.P, Robinson, C.V, Eisenberg, D.
登録日2013-08-08
公開日2014-04-09
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity.
Proc.Natl.Acad.Sci.USA, 111, 2014
4MJH
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Human Hsp27 core domain in complex with C-terminal peptide
分子名称: Heat shock protein beta-1
著者Laganowsky, A, Cascio, D, Sawaya, M.R, Eisenberg, D.
登録日2013-09-03
公開日2014-04-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.599 Å)
主引用文献The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NIN
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DSVISLS segment 101-107 from Human Superoxide Dismutase
分子名称: DSVISLS segment from Superoxide dismutase [Cu-Zn], ZINC ION
著者Sievers, S.A, Sawaya, M.R, Eisenberg, D.
登録日2013-11-06
公開日2013-12-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.402 Å)
主引用文献Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NIO
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GVTGIAQ segment 147-153 from Human Superoxide Dismutase with I149T mutation associated with a familial form of amyotrophic lateral sclerosis
分子名称: GVTGIAQ segment from Superoxide dismutase [Cu-Zn]
著者Sievers, S.A, Sawaya, M.R, Eisenberg, D, Ivanova, M.I.
登録日2013-11-06
公開日2013-12-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS.
Proc.Natl.Acad.Sci.USA, 111, 2014
3SEY
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Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form II)
分子名称: ACETATE ION, GLYCEROL, Maltose-binding periplasmic protein, ...
著者Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-11
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SB6
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Cu-mediated Dimer of T4 Lysozyme D61H/K65H/R76H/R80H by Synthetic Symmetrization
分子名称: CHLORIDE ION, COPPER (II) ION, Lysozyme
著者Soriaga, A.B, Laganowsky, A, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-03
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SEX
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Ni-mediated Dimer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form II)
分子名称: IODIDE ION, Maltose-binding periplasmic protein, NICKEL (II) ION, ...
著者Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-11
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SEU
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Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form III)
分子名称: ACETATE ION, GLYCEROL, Maltose-binding periplasmic protein, ...
著者Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-11
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SGP
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Amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-crystallin B chain
著者Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2011-06-15
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4016 Å)
主引用文献Atomic view of a toxic amyloid small oligomer.
Science, 335, 2012
4NP8
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Structure of an amyloid forming peptide VQIVYK from the second repeat region of tau (alternate polymorph)
分子名称: Microtubule-associated protein tau
著者Landau, M, Eisenberg, D, Sawaya, M.R, Dannenberg, J, Kobko, N.
登録日2013-11-20
公開日2013-12-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Molecular mechanisms for protein-encoded inheritance.
Nat.Struct.Mol.Biol., 16, 2009
3L1E
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Bovine AlphaA crystallin Zinc Bound
分子名称: Alpha-crystallin A chain, GLYCEROL, ZINC ION
著者Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2009-12-11
公開日2010-05-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function.
Protein Sci., 19, 2010
3L1G
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Human AlphaB crystallin
分子名称: Alpha-crystallin B chain, SULFATE ION
著者Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2009-12-11
公開日2010-05-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function.
Protein Sci., 19, 2010
4OIK
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(Quasi-)Racemic X-ray crystal structure of glycosylated chemokine Ser-CCL1.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1, CITRIC ACID, ...
著者Okamoto, R, Mandal, K, Sawaya, M.R, Kajihara, Y, Yeates, T.O, Kent, S.B.H.
登録日2014-01-19
公開日2014-05-07
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献(Quasi-)Racemic X-ray Structures of Glycosylated and Non-Glycosylated Forms of the Chemokine Ser-CCL1 Prepared by Total Chemical Synthesis.
Angew.Chem.Int.Ed.Engl., 53, 2014
3SB5
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Zn-mediated Trimer of T4 Lysozyme R125C/E128C by Synthetic Symmetrization
分子名称: CHLORIDE ION, GLYCEROL, Lysozyme, ...
著者Laganowsky, A, Soriaga, A.B, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-03
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SGS
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Amyloid-related segment of alphaB-crystallin residues 95-100
分子名称: Alpha-crystallin B chain
著者Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2011-06-15
公開日2012-03-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.703 Å)
主引用文献Atomic view of a toxic amyloid small oligomer.
Science, 335, 2012
4ONK
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[Leu-5]-Enkephalin mutant - YVVFL
分子名称: [Leu-5]-Enkephalin mutant - YVVFL
著者Sangwan, S, Eisenberg, D, Sawaya, M.R, Do, T.D, Bowers, M.T, Lapointe, N.E, Teplow, D.B, Feinstein, S.C.
登録日2014-01-28
公開日2014-07-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Factors that drive Peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants.
J.Phys.Chem.B, 118, 2014
3SEW
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Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form I)
分子名称: CHLORIDE ION, GLYCEROL, Maltose-binding periplasmic protein, ...
著者Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-11
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SBB
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Disulphide-mediated Tetramer of T4 Lysozyme R76C/R80C by Synthetic Symmetrization
分子名称: CHLORIDE ION, Lysozyme
著者Laganowsky, A, Soriaga, A.B, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-03
公開日2011-09-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.434 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
4OLP
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Ligand-free structure of the GrpU microcompartment shell protein from Pectobacterium wasabiae
分子名称: GrpU microcompartment shell protein
著者Wheatley, N.M, Thompson, M.C, Gidaniyan, S.D, Sawaya, M.R, Jorda, J, Yeates, T.O.
登録日2014-01-24
公開日2014-07-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Identification of a unique fe-s cluster binding site in a glycyl-radical type microcompartment shell protein.
J.Mol.Biol., 426, 2014
4OLR
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[Leu-5]-Enkephalin mutant - YVVFV
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, [Leu-5]-Enkephalin mutant - YVVFV
著者Sangwan, S, Eisenberg, D, Sawaya, M.R, Do, T.D, Bowers, M.T, Lapointe, N.E, Teplow, D.B, Feinstein, S.C.
登録日2014-01-24
公開日2014-07-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Factors that drive Peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants.
J.Phys.Chem.B, 118, 2014

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