7MJA
 
 | | HLA-A*24:02 bound to Neuroblastoma derived PHOX2B peptide | | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | 著者 | Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G. | | 登録日 | 2021-04-19 | | 公開日 | 2021-08-18 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Nature, 599, 2021
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7MJ8
 | | HLA-A*02:01 bound to Neuroblastoma Derived IGFBPL1 peptide | | 分子名称: | Beta-2-microglobulin, GLYCEROL, Insulin-like growth factor-binding protein-like 1 peptide, ... | | 著者 | Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G. | | 登録日 | 2021-04-19 | | 公開日 | 2021-08-18 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Nature, 599, 2021
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4ZPC
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8GKC
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6NBL
 | | Cytochrome P450cam-putidaredoxin complex bound to camphor and cyanide | | 分子名称: | 1,1'-hexane-1,6-diyldipyrrolidine-2,5-dione, CALCIUM ION, CAMPHOR, ... | | 著者 | Follmer, A.H, Tripathi, S.M, Poulos, T.L. | | 登録日 | 2018-12-07 | | 公開日 | 2019-03-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Ligand and Redox Partner Binding Generates a New Conformational State in Cytochrome P450cam (CYP101A1).
J. Am. Chem. Soc., 141, 2019
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6BJK
 | | Human ABO(H) blood group glycosyltransferase GTB D302C mutant | | 分子名称: | ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase), ... | | 著者 | Gagnon, S.M.L, Legg, M.S.G, Evans, S.V. | | 登録日 | 2017-11-06 | | 公開日 | 2018-09-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Glycobiology, 28, 2018
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6APM
 | | Hen egg-white lysozyme (WT), solved with serial millisecond crystallography using synchrotron radiation | | 分子名称: | Lysozyme C, SODIUM ION | | 著者 | Lyubimov, A.Y, Mathews, I.I, Uervivojnangkoorn, M, Soltis, S.M, Cohen, A.E. | | 登録日 | 2017-08-17 | | 公開日 | 2018-04-04 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The Conformational Flexibility of the Acyltransferase from the Disorazole Polyketide Synthase Is Revealed by an X-ray Free-Electron Laser Using a Room-Temperature Sample Delivery Method for Serial Crystallography.
Biochemistry, 56, 2017
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5WEG
 | | Crystal Structure of UDP-glucose pyrophosphorylase from Sugarcane | | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, UTP--glucose-1-phosphate uridylyltransferase | | 著者 | Cotrim, C.A, Soares, J.S.M, Kobe, B, Menossi, M. | | 登録日 | 2017-07-10 | | 公開日 | 2018-03-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure and insights into the oligomeric state of UDP-glucose pyrophosphorylase from sugarcane.
PLoS ONE, 13, 2018
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8GN3
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8GN4
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1HWG
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7LVO
 | | Cryptococcus neoformans GAR synthetase | | 分子名称: | 1,2-ETHANEDIOL, phosphoribosyl-glycinamide (GAR) synthetase | | 著者 | Chua, S.M.H, Luo, Z, Lim, B.Y.J, Kobe, B, Fraser, J.A. | | 登録日 | 2021-02-26 | | 公開日 | 2021-08-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets.
J.Biol.Chem., 297, 2021
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7LVP
 | | Cryptococcus neoformans AIR synthetase | | 分子名称: | 1,2-ETHANEDIOL, AIR synthase, GLYCINE, ... | | 著者 | Chua, S.M.H, Luo, Z, Lim, B.Y.J, Kobe, B, Fraser, J.A. | | 登録日 | 2021-02-26 | | 公開日 | 2021-08-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets.
J.Biol.Chem., 297, 2021
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5DD1
 | | Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques | | 分子名称: | ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB LIGHT CHAIN | | 著者 | Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F. | | 登録日 | 2015-08-24 | | 公開日 | 2016-05-11 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.597 Å) | | 主引用文献 | Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
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5UQE
 | | Multidomain structure of human kidney-type glutaminase(KGA/GLS) | | 分子名称: | Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide) | | 著者 | Pasquali, C.C, Dias, S.M.G, Ambrosio, A.L.B. | | 登録日 | 2017-02-08 | | 公開日 | 2017-05-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
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6NPR
 | | Crystal structure of H-2Dd with C84-C139 disulfide in complex with gp120 derived peptide P18-I10 | | 分子名称: | ARG-GLY-PRO-GLY-ARG-ALA-PHE-VAL-THR-ILE, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | | 著者 | Toor, J, McShan, A.C, Tripathi, S.M, Sgourakis, N.G. | | 登録日 | 2019-01-18 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection.
Proc.Natl.Acad.Sci.USA, 116, 2019
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7MGQ
 | | AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans | | 分子名称: | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase, MAGNESIUM ION | | 著者 | Wizrah, M.S, Chua, S.M.H, Luo, Z, Manik, M.K, Pan, M, Whyte, J.M, Robertson, A.B, Kappler, U, Kobe, B, Fraser, J.A. | | 登録日 | 2021-04-13 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans.
J.Biol.Chem., 298, 2022
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2YLJ
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6APK
 | | Trans-acting transferase from Disorazole synthase solved by serial femtosecond XFEL crystallography | | 分子名称: | DisD protein | | 著者 | Lyubimov, A.Y, Mathews, I.I, Uervivojnangkoorn, M, Khosla, C, Soltis, S.M, Cohen, A.E. | | 登録日 | 2017-08-17 | | 公開日 | 2018-04-04 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The Conformational Flexibility of the Acyltransferase from the Disorazole Polyketide Synthase Is Revealed by an X-ray Free-Electron Laser Using a Room-Temperature Sample Delivery Method for Serial Crystallography.
Biochemistry, 56, 2017
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3IGS
 | | Structure of the Salmonella enterica N-acetylmannosamine-6-phosphate 2-epimerase | | 分子名称: | 2-acetamido-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, N-acetylmannosamine-6-phosphate 2-epimerase 2, ... | | 著者 | Anderson, S.M, Wawrzak, Z, Gordon, E, Skarina, T, Papazisi, L, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2009-07-28 | | 公開日 | 2009-08-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 |
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3UF1
 | | Crystal Structure of Vimentin (fragment 144-251) from Homo sapiens, Northeast Structural Genomics Consortium Target HR4796B | | 分子名称: | Vimentin | | 著者 | Kuzin, A, Abashidze, M, Vorobiev, S.M, Patel, P, Xiao, R, Ciccosanti, C, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2011-10-31 | | 公開日 | 2011-11-30 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | The structure of vimentin linker 1 and rod 1B domains characterized by site-directed spin-labeling electron paramagnetic resonance (SDSL-EPR) and X-ray crystallography.
J.Biol.Chem., 287, 2012
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3UFL
 | | Discovery of Pyrrolidine-based b-Secretase Inhibitors: Lead Advancement through Conformational Design for Maintenance of Ligand Binding Efficiency | | 分子名称: | (1R,4'S)-3,4-dihydro-2H-spiro[naphthalene-1,3'-pyrrolidin]-4'-yl[(2S,4R)-2,4-diphenylpiperidin-1-yl]methanone, Beta-secretase 1, GLYCEROL, ... | | 著者 | Allison, T, Munshi, S, Soisson, S.M. | | 登録日 | 2011-11-01 | | 公開日 | 2012-01-18 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery of pyrrolidine-based beta-secretase inhibitors: Lead advancement through conformational design for maintenance of ligand binding efficiency.
Bioorg.Med.Chem.Lett., 22, 2012
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6APG
 | | Trans-acting transferase from Disorazole synthase with malonate | | 分子名称: | CALCIUM ION, DisD protein, GLYCEROL, ... | | 著者 | Mathews, I.I, Lyubimov, A.Y, Soltis, S.M, Khosla, C, Robbins, T, Cohen, A.E. | | 登録日 | 2017-08-17 | | 公開日 | 2018-04-04 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Conformational Flexibility of the Acyltransferase from the Disorazole Polyketide Synthase Is Revealed by an X-ray Free-Electron Laser Using a Room-Temperature Sample Delivery Method for Serial Crystallography.
Biochemistry, 56, 2017
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5BPA
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3GOA
 | | Crystal structure of the Salmonella typhimurium FadA 3-ketoacyl-CoA thiolase | | 分子名称: | 3-ketoacyl-CoA thiolase, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Anderson, S.M, Skarina, T, Onopriyenko, O, Wawrzak, Z, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2009-03-18 | | 公開日 | 2009-03-31 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 |
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