8V80
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![BU of 8v80 by Molmil](/molmil-images/mine/8v80) | Alpha7-nicotinic acetylcholine receptor bound to epibatidine and (-)-TQS | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (3aR,4S,9bS)-4-(naphthalen-1-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, ... | 著者 | Burke, S.M, Noviello, C.M, Hibbs, R.E. | 登録日 | 2023-12-04 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.34 Å) | 主引用文献 | Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation. Cell, 187, 2024
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8V8A
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![BU of 8v8a by Molmil](/molmil-images/mine/8v8a) | Alpha7-nicotinic acetylcholine receptor time resolved bound to epibatidine and PNU-120596 desensitized intermediate state | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Burke, S.M, Noviello, C.M, Hibbs, R.E. | 登録日 | 2023-12-05 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.19 Å) | 主引用文献 | Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation. Cell, 187, 2024
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8V8D
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![BU of 8v8d by Molmil](/molmil-images/mine/8v8d) | Alpha7-nicotinic acetylcholine receptor time resolved bound to epibatidine and PNU-120596 asymmetric state 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Burke, S.M, Noviello, C.M, Hibbs, R.E. | 登録日 | 2023-12-05 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation. Cell, 187, 2024
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8V89
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![BU of 8v89 by Molmil](/molmil-images/mine/8v89) | Alpha7-nicotinic acetylcholine receptor time resolved resting state | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Burke, S.M, Noviello, C.M, Hibbs, R.E. | 登録日 | 2023-12-05 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | 主引用文献 | Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation. Cell, 187, 2024
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8V86
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![BU of 8v86 by Molmil](/molmil-images/mine/8v86) | Alpha7-nicotinic acetylcholine receptor bound to GAT107 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (3aR,4S,9bS)-4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, ... | 著者 | Burke, S.M, Noviello, C.M, Hibbs, R.E. | 登録日 | 2023-12-04 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.47 Å) | 主引用文献 | Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation. Cell, 187, 2024
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5M56
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![BU of 5m56 by Molmil](/molmil-images/mine/5m56) | Monoclinic complex structure of human protein kinase CK2 catalytic subunit (isoform CK2alpha') with the inhibitor 4'-carboxy-6,8-chloro-flavonol (FLC21) | 分子名称: | 4-[6,8-bis(chloranyl)-3-oxidanyl-4-oxidanylidene-chromen-2-yl]benzoic acid, CHLORIDE ION, Casein kinase II subunit alpha', ... | 著者 | Niefind, K, Bischoff, N, Yarmoluk, S.M, Bdzhola, V.G, Golub, A.G, Balanda, A.O, Prykhod'ko, A.O. | 登録日 | 2016-10-20 | 公開日 | 2017-01-18 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.237 Å) | 主引用文献 | Structural Hypervariability of the Two Human Protein Kinase CK2 Catalytic Subunit Paralogs Revealed by Complex Structures with a Flavonol- and a Thieno[2,3-d]pyrimidine-Based Inhibitor. Pharmaceuticals, 10, 2017
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3KAE
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![BU of 3kae by Molmil](/molmil-images/mine/3kae) | Cdc27 N-terminus | 分子名称: | CHLORIDE ION, GLYCEROL, Possible protein of nuclear scaffold, ... | 著者 | Barford, D, Zhang, Z, Roe, S.M. | 登録日 | 2009-10-19 | 公開日 | 2010-03-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | 主引用文献 | Molecular structure of the N-terminal domain of the APC/C subunit Cdc27 reveals a homo-dimeric tetratricopeptide repeat architecture J.Mol.Biol., 397, 2010
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3K9P
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![BU of 3k9p by Molmil](/molmil-images/mine/3k9p) | The crystal structure of E2-25K and ubiquitin complex | 分子名称: | Ubiquitin, Ubiquitin-conjugating enzyme E2 K | 著者 | Kang, G.B, Ko, S, Song, S.M, Lee, W, Eom, S.H. | 登録日 | 2009-10-16 | 公開日 | 2010-09-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity J.Biol.Chem., 285, 2010
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3J1Q
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![BU of 3j1q by Molmil](/molmil-images/mine/3j1q) | Structure of AAV-DJ, a Retargeted Gene Therapy Vector: Cryo-Electron Microscopy at 4.5A resolution | 分子名称: | Adeno-associated virus DJ | 著者 | Lerch, T.F, O'Donnell, J.K, Meyer, N.L, Xie, Q, Taylor, K.A, Stagg, S.M, Chapman, M.S. | 登録日 | 2012-04-30 | 公開日 | 2012-08-22 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structure of AAV-DJ, a retargeted gene therapy vector: cryo-electron microscopy at 4.5 A resolution. Structure, 20, 2012
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3J31
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![BU of 3j31 by Molmil](/molmil-images/mine/3j31) | Life in the extremes: atomic structure of Sulfolobus Turreted Icosahedral Virus | 分子名称: | A223 penton base, A55 membrane protein, C381 turret protein, ... | 著者 | Veesler, D, Ng, T.S, Sendamarai, A.K, Eilers, B.J, Lawrence, C.M, Lok, S.M, Young, M.J, Johnson, J.E, Fu, C.-Y. | 登録日 | 2013-02-18 | 公開日 | 2013-05-01 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Atomic structure of the 75 MDa extremophile Sulfolobus turreted icosahedral virus determined by CryoEM and X-ray crystallography. Proc.Natl.Acad.Sci.USA, 110, 2013
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6NAC
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![BU of 6nac by Molmil](/molmil-images/mine/6nac) | Crystal structure of [FeFe]-hydrogenase I (CpI) solved with single pulse free electron laser data | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, IRON/SULFUR CLUSTER, ... | 著者 | Cohen, A.E, Davidson, C.M, Zadvornyy, O.A, Keable, S.M, Lyubimov, A.Y, Song, J, McPhillips, S.E, Soltis, S.M, Peters, J.W. | 登録日 | 2018-12-05 | 公開日 | 2019-12-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Tuning Catalytic Bias of Hydrogen Gas Producing Hydrogenases. J.Am.Chem.Soc., 142, 2020
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1UOT
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![BU of 1uot by Molmil](/molmil-images/mine/1uot) | HUMAN CD55 DOMAINS 3 & 4 | 分子名称: | COMPLEMENT DECAY-ACCELERATING FACTOR | 著者 | Williams, P, Chaudhry, Y, Goodfellow, I.G, Billington, J, Spiller, B, Evans, D.J, Lea, S.M. | 登録日 | 2003-09-23 | 公開日 | 2003-09-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A J.Biol.Chem., 278, 2003
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2VW5
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![BU of 2vw5 by Molmil](/molmil-images/mine/2vw5) | Structure Of The Hsp90 Inhibitor 7-O-carbamoylpremacbecin Bound To The N- Terminus Of Yeast Hsp90 | 分子名称: | (4E,8S,9R,10E,12S,13R,14S,16R)-13,20-dihydroxy-14-methoxy-4,8,10,12,16-pentamethyl-3-oxo-2-azabicyclo[16.3.1]docosa-1(22),4,10,18,20-pentaen-9-yl carbamate, ATP-DEPENDENT MOLECULAR CHAPERONE HSP82, SULFATE ION | 著者 | Roe, S.M, Prodromou, C, Pearl, L.H. | 登録日 | 2008-06-16 | 公開日 | 2008-09-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Optimizing Natural Products by Biosynthetic Engineering: Discovery of Nonquinone Hsp90 Inhibitors. J.Med.Chem., 51, 2008
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6N6P
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![BU of 6n6p by Molmil](/molmil-images/mine/6n6p) | Crystal structure of [FeFe]-hydrogenase in the presence of 7 mM Sodium dithionite | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, IRON/SULFUR CLUSTER, ... | 著者 | Zadvornyy, O.A, Keable, S.M, Peters, J.W. | 登録日 | 2018-11-26 | 公開日 | 2019-12-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Tuning Catalytic Bias of Hydrogen Gas Producing Hydrogenases. J.Am.Chem.Soc., 142, 2020
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1NKZ
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![BU of 1nkz by Molmil](/molmil-images/mine/1nkz) | Crystal structure of LH2 B800-850 from Rps. acidophila at 2.0 Angstrom resolution | 分子名称: | BACTERIOCHLOROPHYLL A, BENZAMIDINE, Light-harvesting protein B-800/850, ... | 著者 | Papiz, M.Z, Prince, S.M, Howard, T, Cogdell, R.J, Isaacs, N.W. | 登録日 | 2003-01-06 | 公開日 | 2003-02-25 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The structure and thermal motion of the B800-850 LH2 complex from Rps. acidophila at 2.0 A resolution and 100K : new structural features and functionally relevant motions. J.Mol.Biol., 326, 2003
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2HGX
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![BU of 2hgx by Molmil](/molmil-images/mine/2hgx) | |
2HHF
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![BU of 2hhf by Molmil](/molmil-images/mine/2hhf) | |
2HG8
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![BU of 2hg8 by Molmil](/molmil-images/mine/2hg8) | |
6N59
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![BU of 6n59 by Molmil](/molmil-images/mine/6n59) | 1.0 Angstrom crystal structure of [FeFe]-hydrogenase | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, IRON/SULFUR CLUSTER, ... | 著者 | Zadvornyy, O.A, Keable, S.M, Artz, J.H, Peters, J.W. | 登録日 | 2018-11-21 | 公開日 | 2019-12-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.02 Å) | 主引用文献 | Tuning Catalytic Bias of Hydrogen Gas Producing Hydrogenases. J.Am.Chem.Soc., 142, 2020
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5FD3
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![BU of 5fd3 by Molmil](/molmil-images/mine/5fd3) | Structure of Lin54 tesmin domain bound to DNA | 分子名称: | DNA (5'-D(*CP*AP*GP*TP*TP*TP*CP*AP*AP*AP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*TP*TP*TP*GP*AP*AP*AP*CP*T)-3'), Protein lin-54 homolog, ... | 著者 | Marceau, A.H, Felthousen, J.G, Goetsch, P.D, Lee, H, Tripathi, S.M, Strome, S, Litovchick, L, Rubin, S.M. | 登録日 | 2015-12-15 | 公開日 | 2016-08-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters. Nat Commun, 7, 2016
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2W5Z
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![BU of 2w5z by Molmil](/molmil-images/mine/2w5z) | Ternary Complex of the Mixed Lineage Leukaemia (MLL1) SET Domain with the cofactor product S-Adenosylhomocysteine and histone peptide. | 分子名称: | GLYCEROL, HISTONE PEPTIDE, HISTONE-LYSINE N-METHYLTRANSFERASE HRX, ... | 著者 | Southall, S.M, Wong, P.S, Odho, Z, Roe, S.M, Wilson, J.R. | 登録日 | 2008-12-15 | 公開日 | 2009-02-10 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Basis for the Requirement of Additional Factors for Mll1 Set Domain Activity and Recognition of Epigenetic Marks. Mol.Cell, 33, 2009
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3UGE
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![BU of 3uge by Molmil](/molmil-images/mine/3uge) | Silver Metallated Pseudomonas aeruginosa Azurin at 1.70 A | 分子名称: | Azurin, SILVER ION | 著者 | Panzner, M.J, Billinovich, S.M, Parker, J.A, Bladholm, E, Berry, S.M, Ziegler, C.J, Leeper, T.C. | 登録日 | 2011-11-02 | 公開日 | 2012-11-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Silver Metallation of Pseudomonas aeruginosa Azurin To be Published
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2W5Y
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![BU of 2w5y by Molmil](/molmil-images/mine/2w5y) | Binary Complex of the Mixed Lineage Leukaemia (MLL1) SET Domain with the cofactor product S-Adenosylhomocysteine. | 分子名称: | HISTONE-LYSINE N-METHYLTRANSFERASE HRX, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | 著者 | Southall, S.M, Wong, P.S, Odho, Z, Roe, S.M, WIlson, J.R. | 登録日 | 2008-12-15 | 公開日 | 2009-02-10 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Basis for the Requirement of Additional Factors for Mll1 Set Domain Activity and Recognition of Epigenetic Marks. Mol.Cell, 33, 2009
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2DSH
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![BU of 2dsh by Molmil](/molmil-images/mine/2dsh) | Crystal structure of Lys26 to Tyr mutant of Diphthine synthase | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Mizutani, H, Matsuura, Y, Saraboji, K, Malathy Sony, S.M, Ponnuswamy, M.N, Kumarevel, T.S, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-06-30 | 公開日 | 2006-12-30 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3 To be Published
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1USZ
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![BU of 1usz by Molmil](/molmil-images/mine/1usz) | SeMet AfaE-3 adhesin from Escherichia Coli | 分子名称: | AFIMBRIAL ADHESIN AFA-III, CHLORIDE ION, SULFATE ION | 著者 | Anderson, K.L, Billington, J, Pettigrew, D, Cota, E, Roversi, P, Simpson, P, Chen, H.A, Urvil, P, Dumerle, L, Barlow, P, Medof, E, Smith, R.A.G, Nowicki, B, Le Bouguenec, C, Lea, S.M, Matthews, S. | 登録日 | 2003-12-02 | 公開日 | 2004-08-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.28 Å) | 主引用文献 | High Resolution Studies of the Afa/Dr Adhesin Drae and its Interaction with Chloramphenicol J.Biol.Chem., 279, 2004
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