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PDB: 2512 件

4UBF
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HsMCAK motor domain complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF2C, MAGNESIUM ION
著者Welburn, J.P.I, Talapatra, S.K.
登録日2014-08-12
公開日2015-05-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch.
Elife, 4, 2015
2I0O
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Crystal structure of Anopheles gambiae Ser/Thr phosphatase complexed with Zn2+
分子名称: Ser/Thr phosphatase, ZINC ION
著者Jin, X, Sauder, J.M, Burley, S.K, Shapiro, L, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-08-10
公開日2006-10-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007
2I52
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Crystal structure of protein PTO0218 from Picrophilus torridus, Pfam DUF372
分子名称: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
著者Ramagopal, U.A, Gilmore, J, Toro, R, Bain, K.T, McKenzie, C, Reyes, C, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-08-23
公開日2006-09-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structure of hypothetical protein PTO0218 from Picrophilus torridus
To be Published
4UOQ
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Nucleophile mutant (E324A) of beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04
分子名称: BETA-GALACTOSIDASE, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ...
著者Viborg, A.H, Fredslund, F, Katayama, T, Nielsen, S.K, Svensson, B, Kitaoka, M, Lo Leggio, L, Abou Hachem, M.
登録日2014-06-09
公開日2014-10-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A beta 1-6/ beta 1-3 galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 gives insight into sub-specificities of beta-galactoside catabolism within Bifidobacterium.
Mol. Microbiol., 2014
2I6E
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Crystal structure of protein DR0370 from Deinococcus radiodurans, Pfam DUF178
分子名称: Hypothetical protein, SULFATE ION
著者Tyagi, R, Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-08-28
公開日2006-09-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-ray structures of two proteins belonging to Pfam DUF178 revealed unexpected structural similarity to the DUF191 Pfam family.
Bmc Struct.Biol., 7, 2007
2I9U
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Crystal Structure of Guanine Deaminase from C. acetobutylicum with bound guanine in the active site
分子名称: Cytosine/guanine deaminase related protein, FE (III) ION, GLYCEROL, ...
著者Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-09-06
公開日2006-09-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure of Guanine Deaminase from C. acetobutylicum with bound guanine in the active site
To be Published
5KZ7
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Mark2 complex with 7-[(1S)-1-(4-fluorophenyl)ethyl]-5,5-dimethyl-2-(3-pyridylamino)pyrrolo[2,3-d]pyrimidin-6-one
分子名称: 7-[(1~{S})-1-(4-fluorophenyl)ethyl]-5,5-dimethyl-2-(pyridin-3-ylamino)pyrrolo[2,3-d]pyrimidin-6-one, Serine/threonine-protein kinase MARK2
著者Su, H.P, Munshi, S.K.
登録日2016-07-23
公開日2017-05-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
1VTL
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CO-CRYSTAL STRUCTURE OF TBP RECOGNIZING THE MINOR GROOVE OF A TATA ELEMENT
分子名称: DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*C)-3'), TATA BINDING PROTEIN (TBP)
著者Kim, J.L, Nikolov, D.B, Burley, S.K.
登録日1993-12-17
公開日2011-07-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Co-Crystal Structure of TBP Recognizing the Minor Groove of a TATA Element
Nature, 365, 1993
8FAZ
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Cryo-EM structure of the human BCDX2 complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA repair protein RAD51 homolog 2, DNA repair protein RAD51 homolog 3, ...
著者Jia, L, Wasmuth, E.V, Ruben, E.A, Sung, P, Rawal, Y, Greene, E.C, Meir, A, Olsen, S.K.
登録日2022-11-29
公開日2023-06-21
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structural insights into BCDX2 complex function in homologous recombination.
Nature, 619, 2023
4UOZ
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beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 nucleophile mutant E324A in complex with galactose
分子名称: BETA-GALACTOSIDASE, TRIETHYLENE GLYCOL, ZINC ION, ...
著者Viborg, A.H, Fredslund, F, Katayama, T, Nielsen, S.K, Svensson, B, Kitaoka, M, Lo Leggio, L, Abou Hachem, M.
登録日2014-06-11
公開日2014-10-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A beta 1-6/ beta 1-3 galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 gives insight into sub-specificities of beta-galactoside catabolism within Bifidobacterium.
Mol. Microbiol., 2014
5KUG
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Human mitochondrial calcium uniporter (residues 72-189) crystal structure with lithium
分子名称: Calcium uniporter protein, mitochondrial
著者Mok, M.C.Y, Lee, S.K, Junop, M.S, Stathopulos, P.B.
登録日2016-07-13
公開日2016-09-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations.
Cell Chem Biol, 23, 2016
2I8T
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GDP-mannose mannosyl hydrolase-calcium-GDP-mannose complex
分子名称: CALCIUM ION, GDP-mannose mannosyl hydrolase, GLYCEROL, ...
著者Zou, Y, Li, C, Brunzelle, J.S, Nair, S.K.
登録日2006-09-03
公開日2007-06-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Molecular basis for substrate selectivity and specificity by an LPS biosynthetic enzyme
Biochemistry, 46, 2007
1VOK
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ARABIDOPSIS THALIANA TBP (DIMER)
分子名称: SULFATE ION, TATA-BOX-BINDING PROTEIN
著者Nikolov, D.B, Burley, S.K.
登録日1996-04-29
公開日1996-11-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献2.1 A resolution refined structure of a TATA box-binding protein (TBP).
Nat.Struct.Biol., 1, 1994
2I76
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Crystal structure of protein TM1727 from Thermotoga maritima
分子名称: Hypothetical protein, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Madegowda, M, Eswaramoorthy, S, Seetharaman, J, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-08-30
公開日2006-10-03
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of hypothetical protein TM1727 from Thermatoga maritima
TO BE PUBLISHED
5KUJ
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Human mitochondrial calcium uniporter (residues 72-189) crystal structure with magnesium.
分子名称: Calcium uniporter protein, mitochondrial, MAGNESIUM ION
著者Mok, M.C.Y, Lee, S.K, Junop, M.S, Stathopulos, P.B.
登録日2016-07-13
公開日2016-09-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations.
Cell Chem Biol, 23, 2016
5DOO
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BU of 5doo by Molmil
The structure of PKMT2 from Rickettsia typhi
分子名称: CALCIUM ION, protein lysine methyltransferase 2
著者Noinaj, N, Abeykoon, A, He, Y, Yang, D.C, Buchanan, S.K.
登録日2015-09-11
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.133 Å)
主引用文献Structural Insights into Substrate Recognition and Catalysis in Outer Membrane Protein B (OmpB) by Protein-lysine Methyltransferases from Rickettsia.
J.Biol.Chem., 291, 2016
7SOM
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BU of 7som by Molmil
Ciliary C2 central pair apparatus isolated from Chlamydomonas reinhardtii
分子名称: Cilia- and flagella-associated protein 20, FAP147, FAP178, ...
著者Gui, M, Wang, X, Dutcher, S.K, Brown, A, Zhang, R.
登録日2021-11-01
公開日2022-04-13
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ciliary central apparatus structure reveals mechanisms of microtubule patterning.
Nat.Struct.Mol.Biol., 29, 2022
7SQC
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Ciliary C1 central pair apparatus isolated from Chlamydomonas reinhardtii
分子名称: ADENOSINE-5'-DIPHOSPHATE, CPC1, Calmodulin, ...
著者Gui, M, Wang, X, Dutcher, S.K, Brown, A, Zhang, R.
登録日2021-11-05
公開日2022-04-13
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Ciliary central apparatus structure reveals mechanisms of microtubule patterning.
Nat.Struct.Mol.Biol., 29, 2022
1YSN
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Solution structure of the anti-apoptotic protein Bcl-xL complexed with an acyl-sulfonamide-based ligand
分子名称: 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-X
著者Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H.
登録日2005-02-08
公開日2005-06-07
最終更新日2023-11-29
実験手法SOLUTION NMR
主引用文献An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
2IMH
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Crystal structure of protein SPO2555 from Silicibacter pomeroyi, Pfam DUF1028
分子名称: Hypothetical protein UNP Q5LQD5_SILPO
著者Bonanno, J.B, Dickey, M, Bain, K.T, Slocombe, A, Ozyurt, S, Wasserman, S, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-10-04
公開日2006-10-17
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Crystal structure of hypothetical protein from Silicibacter pomeroyi
To be Published
2IMR
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Crystal structure of amidohydrolase DR_0824 from Deinococcus radiodurans
分子名称: Hypothetical protein DR_0824, ZINC ION
著者Eswaramoorthy, S, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-10-04
公開日2006-10-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal structure of a hypothetical protein DR_0824 from Deinococcus radiodurans
To be Published
7OD3
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SARS CoV-2 Spike protein, Bristol UK Deletion variant, Closed conformation, C3 symmetry
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, Spike glycoprotein
著者Toelzer, C, Gupta, K, Yadav, S.K.N, Borucu, U, Schaffitzel, C, Berger, I.
登録日2021-04-28
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2.
Nat Commun, 13, 2022
7ODL
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SARS CoV-2 Spike protein, Bristol UK Deletion variant, Closed conformation, C1 symmetry
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, Spike glycoprotein
著者Toelzer, C, Gupta, K, Yadav, S.K.N, Borucu, U, Schaffitzel, C, Berger, I.
登録日2021-04-29
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2.
Nat Commun, 13, 2022
6WIM
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CdiB from Escherichia coli
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Outer membrane transporter CdiB
著者Guerin, J, Botos, I, Buchanan, S.K.
登録日2020-04-10
公開日2020-11-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insight into toxin secretion by contact dependent growth inhibition transporters.
Elife, 9, 2020
7NWG
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Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by Blasticidin S.
分子名称: 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ...
著者Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C.
登録日2021-03-16
公開日2021-07-07
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA.
Nucleic Acids Res., 49, 2021

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