6MR1
 
 | | RbcS-like subdomain of CcmM | | 分子名称: | CHLORIDE ION, COBALT (II) ION, Carbon dioxide concentrating mechanism protein, ... | | 著者 | Ryan, P, Kimber, M.S. | | 登録日 | 2018-10-11 | | 公開日 | 2019-01-02 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | The small RbcS-like domains of the beta-carboxysome structural protein CcmM bind RubisCO at a site distinct from that binding the RbcS subunit.
J. Biol. Chem., 294, 2019
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6OSM
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6OSJ
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7LC9
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6UAI
 | | Imidazole-triggered RAS-specific subtilisin SUBT_BACAM complexed with YSAM peptide | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Toth, E.A, Bryan, P.N, Orban, J. | | 登録日 | 2019-09-10 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Engineering subtilisin proteases that specifically degrade active RAS.
Commun Biol, 4, 2021
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6UAO
 | | Imidazole-triggered RAS-specific subtilisin SUBT_BACAM complexed with the peptide EEYSAM | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Peptide EEYSAM, ... | | 著者 | Toth, E.A, Bryan, P.N, Orban, J. | | 登録日 | 2019-09-11 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Engineering subtilisin proteases that specifically degrade active RAS.
Commun Biol, 4, 2021
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1AJ0
 | | CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E. COLI DIHYDROPTEROATE SYNTHASE | | 分子名称: | 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, DIHYDROPTEROATE SYNTHASE, SULFANILAMIDE, ... | | 著者 | Achari, A, Somers, D.O, Champness, J.N, Bryant, P.K, Rosemond, J, Stammers, D.K. | | 登録日 | 1997-05-14 | | 公開日 | 1998-05-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase.
Nat.Struct.Biol., 4, 1997
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1AJZ
 | | STRUCTURE OF DIHYDROPTEROATE PYROPHOSPHORYLASE | | 分子名称: | DIHYDROPTEROATE SYNTHASE, SULFATE ION | | 著者 | Achari, A, Somers, D.O, Champness, J.N, Bryant, P.K, Rosemond, J, Stammers, D.K. | | 登録日 | 1997-05-13 | | 公開日 | 1998-05-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase.
Nat.Struct.Biol., 4, 1997
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1AJ2
 | | CRYSTAL STRUCTURE OF A BINARY COMPLEX OF E. COLI DIHYDROPTEROATE SYNTHASE | | 分子名称: | DIHYDROPTEROATE SYNTHASE, SULFATE ION, [7,8-DIHYDRO-PTERIN-6-YL METHANYL]-PHOSPHONOPHOSPHATE | | 著者 | Achari, A, Somers, D.O, Champness, J.N, Bryant, P.K, Rosemond, J, Stammers, D.K. | | 登録日 | 1997-05-14 | | 公開日 | 1998-05-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase.
Nat.Struct.Biol., 4, 1997
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6UBE
 | | Azide-triggered subtilisin SUBT_BACAM complexed with the peptide LFRAL | | 分子名称: | AZIDE ION, GLYCEROL, Peptide LFRAL, ... | | 著者 | Toth, E.A, Bryan, P.N, Orban, J, Gallagher, D.T, Custer, G. | | 登録日 | 2019-09-11 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Engineering subtilisin proteases that specifically degrade active RAS.
Commun Biol, 4, 2021
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6U9L
 | | Imidazole-triggered RAS-specific subtilisin SUBT_BACAM | | 分子名称: | GLYCEROL, POTASSIUM ION, SUBTILISIN BPN', ... | | 著者 | Toth, E.A, Bryan, P.N, Orban, J. | | 登録日 | 2019-09-09 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Engineering subtilisin proteases that specifically degrade active RAS.
Commun Biol, 4, 2021
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1DYR
 | | THE STRUCTURE OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE TO 1.9 ANGSTROMS RESOLUTION | | 分子名称: | DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TRIMETHOPRIM | | 著者 | Champness, J.N, Achari, A, Ballantine, S.P, Bryant, P.K, Delves, C.J, Stammers, D.K. | | 登録日 | 1994-09-14 | | 公開日 | 1995-10-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | The structure of Pneumocystis carinii dihydrofolate reductase to 1.9 A resolution.
Structure, 2, 1994
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1DY3
 | | Ternary complex of 7,8-dihydro-6-hydroxymethylpterinpyrophosphokinase from Escherichia coli with ATP and a substrate analogue. | | 分子名称: | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 7,8-DIHYDRO-6-HYDROXYMETHYL-7-METHYL-7-[2-PHENYLETHYL]-PTERIN, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Stammers, D.K, Achari, A, Somers, D.O, Bryant, P.K, Rosemond, J, Scott, D.L, Champness, J.N. | | 登録日 | 2000-01-21 | | 公開日 | 2000-08-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | 2.0A X-Ray Structure of the Ternary Complex of 7,8-Dihydro-6-Hydroxymethylpterinpyrophosphokinase from Escherichia Coli with ATP and a Substrate Analogue
FEBS Lett., 456, 1999
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2JWS
 | | Solution NMR structures of two designed proteins with 88% sequence identity but different fold and function | | 分子名称: | Ga88 | | 著者 | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | | 登録日 | 2007-10-24 | | 公開日 | 2008-09-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structures of two designed proteins with high sequence identity but different fold and function
Proc.Natl.Acad.Sci.Usa, 105, 2008
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1PGA
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7MN2
 | | Rules for designing protein fold switches and their implications for the folding code | | 分子名称: | Sb2 | | 著者 | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | | 登録日 | 2021-04-30 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Design and characterization of a protein fold switching network.
Nat Commun, 14, 2023
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7MP7
 | | Rules for designing protein fold switches and their implications for the folding code | | 分子名称: | Sb3 | | 著者 | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | | 登録日 | 2021-05-04 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Design and characterization of a protein fold switching network.
Nat Commun, 14, 2023
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7MN1
 | | Rules for designing protein fold switches and their implications for the folding code | | 分子名称: | Sa1 | | 著者 | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | | 登録日 | 2021-04-30 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Design and characterization of a protein fold switching network.
Nat Commun, 14, 2023
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7MQ4
 | | Rules for designing protein fold switches and their implications for the folding code | | 分子名称: | Sb1 | | 著者 | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | | 登録日 | 2021-05-05 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Design and characterization of a protein fold switching network.
Nat Commun, 14, 2023
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1PGB
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2LHG
 | | GB98-T25I solution structure | | 分子名称: | GB98 | | 著者 | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | | 登録日 | 2011-08-08 | | 公開日 | 2012-02-29 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mutational tipping points for switching protein folds and functions.
Structure, 20, 2012
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2LHC
 | | Ga98 solution structure | | 分子名称: | Ga98 | | 著者 | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | | 登録日 | 2011-08-08 | | 公開日 | 2012-02-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mutational tipping points for switching protein folds and functions.
Structure, 20, 2012
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2LHD
 | | GB98 solution structure | | 分子名称: | GB98 | | 著者 | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | | 登録日 | 2011-08-08 | | 公開日 | 2012-02-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mutational tipping points for switching protein folds and functions.
Structure, 20, 2012
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1SPB
 | | SUBTILISIN BPN' PROSEGMENT (77 RESIDUES) COMPLEXED WITH A MUTANT SUBTILISIN BPN' (266 RESIDUES). CRYSTAL PH 4.6. CRYSTALLIZATION TEMPERATURE 20 C DIFFRACTION TEMPERATURE-160 C | | 分子名称: | SODIUM ION, SUBTILISIN BPN', SUBTILISIN BPN' PROSEGMENT | | 著者 | Gallagher, D.T, Gilliland, G.L, Wang, L, Bryan, P.N. | | 登録日 | 1995-06-21 | | 公開日 | 1995-10-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The prosegment-subtilisin BPN' complex: crystal structure of a specific 'foldase'.
Structure, 3, 1995
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1SUB
 | | CALCIUM-INDEPENDENT SUBTILISIN BY DESIGN | | 分子名称: | ACETONE, CALCIUM ION, POTASSIUM ION, ... | | 著者 | Gallagher, T, Bryan, P, Gilliland, G.L. | | 登録日 | 1992-06-10 | | 公開日 | 1994-01-31 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Calcium-independent subtilisin by design.
Proteins, 16, 1993
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