5L9N
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![BU of 5l9n by Molmil](/molmil-images/mine/5l9n) | Structure of uridylylated GlnB from Escherichia coli bound to ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Nitrogen regulatory protein P-II 1 | Authors: | Rubio, V, Palanca, C. | Deposit date: | 2016-06-10 | Release date: | 2017-04-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Effects of T-loop modification on the PII-signalling protein: structure of uridylylated Escherichia coli GlnB bound to ATP. Environ Microbiol Rep, 9, 2017
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2YFK
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7QDH
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![BU of 7qdh by Molmil](/molmil-images/mine/7qdh) | SARS-CoV-2 S protein S:D614G mutant 1-up | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin | Authors: | Ginex, T, Marco-Marin, C, Wieczor, M, Mata, C.P, Krieger, J, Lopez-Redondo, M.L, Frances-Gomez, C, Ruiz-Rodriguez, P, Melero, R, Sanchez-Sorzano, C.O, Martinez, M, Gougeard, N, Forcada-Nadal, A, Zamora-Caballero, S, Gozalbo-Rovira, R, Sanz-Frasquet, C, Bravo, J, Rubio, V, Marina, A, Geller, R, Comas, I, Gil, C, Coscolla, M, Orozco, M, LLacer, J.L, Carazo, J.M. | Deposit date: | 2021-11-27 | Release date: | 2022-05-25 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: The case of the spike A222V mutation. Plos Pathog., 18, 2022
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7QDG
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![BU of 7qdg by Molmil](/molmil-images/mine/7qdg) | SARS-CoV-2 S protein S:A222V + S:D614G mutant 1-up | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ginex, T, Marco-Marin, C, Wieczor, M, Mata, C.P, Krieger, J, Lopez-Redondo, M.L, Frances-Gomez, C, Ruiz-Rodriguez, P, Melero, R, Sanchez-Sorzano, C.O, Martinez, M, Gougeard, N, Forcada-Nadal, A, Zamora-Caballero, S, Gozalbo-Rovira, R, Sanz-Frasquet, C, Bravo, J, Rubio, V, Marina, A, Geller, R, Comas, I, Gil, C, Coscolla, M, Orozco, M, LLacer, J.L, Carazo, J.M. | Deposit date: | 2021-11-27 | Release date: | 2022-05-25 | Last modified: | 2022-08-24 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: The case of the spike A222V mutation. Plos Pathog., 18, 2022
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1GSJ
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![BU of 1gsj by Molmil](/molmil-images/mine/1gsj) | Selenomethionine substituted N-acetyl-L-glutamate kinase from Escherichia coli complexed with its substrate n-acetyl-L-glutamate and its substrate analog AMPPNP | Descriptor: | ACETYLGLUTAMATE KINASE, MAGNESIUM ION, N-ACETYL-L-GLUTAMATE, ... | Authors: | Ramon-Maiques, S, Marina, A, Gil-Ortiz, F, Fita, I, Rubio, V. | Deposit date: | 2002-01-07 | Release date: | 2002-05-16 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of Acetylglutamate Kinase, a Key Enzyme for Arginine Biosynthesis and a Prototype for the Amino Acid Kinase Enzyme Family, During Catalysis Structure, 10, 2002
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4X1E
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![BU of 4x1e by Molmil](/molmil-images/mine/4x1e) | Crystal structure of unliganded E. coli transcriptional regulator RutR, W167A mutant | Descriptor: | HTH-type transcriptional regulator RutR | Authors: | Nguyen Le Minh, P, de Cima, S, Bervoets, I, Maes, D, Rubio, V, Charlier, D. | Deposit date: | 2014-11-24 | Release date: | 2015-01-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Ligand binding specificity of RutR, a member of the TetR family of transcription regulators in Escherichia coli. Febs Open Bio, 5, 2015
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1GS5
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![BU of 1gs5 by Molmil](/molmil-images/mine/1gs5) | N-acetyl-L-glutamate kinase from Escherichia coli complexed with its substrate N-acetylglutamate and its substrate analog AMPPNP | Descriptor: | ACETYLGLUTAMATE KINASE, MAGNESIUM ION, N-ACETYL-L-GLUTAMATE, ... | Authors: | Ramon-Maiques, S, Marina, A, Gil-Ortiz, F, Fita, I, Rubio, V. | Deposit date: | 2001-12-28 | Release date: | 2002-05-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of Acetylglutamate Kinase, a Key Enzyme for Arginine Biosynthesis and a Prototype for the Amino Acid Kinase Enzyme Family, During Catalysis Structure, 10, 2002
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2BUF
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![BU of 2buf by Molmil](/molmil-images/mine/2buf) | Arginine Feed-Back Inhibitable Acetylglutamate Kinase | Descriptor: | ACETYLGLUTAMATE KINASE, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Ramon-Maiques, S, Fernandez-Murga, M.L, Vagin, A, Fita, I, Rubio, V. | Deposit date: | 2005-06-12 | Release date: | 2005-12-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural Bases of Feed-Back Control of Arginine Biosynthesis, Revealed by the Structure of Two Hexameric N-Acetylglutamate Kinases, from Thermotoga Maritima and Pseudomonas Aeruginosa J.Mol.Biol., 356, 2006
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1B7B
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![BU of 1b7b by Molmil](/molmil-images/mine/1b7b) | Carbamate kinase from Enterococcus faecalis | Descriptor: | CARBAMATE KINASE, SULFATE ION | Authors: | Marina, A, Alzari, P.M, Bravo, J, Uriarte, M, Barcelona, B, Fita, I, Rubio, V. | Deposit date: | 1999-01-20 | Release date: | 2000-01-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Carbamate kinase: New structural machinery for making carbamoyl phosphate, the common precursor of pyrimidines and arginine. Protein Sci., 8, 1999
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1E19
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![BU of 1e19 by Molmil](/molmil-images/mine/1e19) | Structure of the carbamate kinase-like carbamoyl phosphate synthetase from the hyperthermophilic archaeon Pyrococcus furiosus bound to ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CARBAMATE KINASE, MAGNESIUM ION | Authors: | Ramon-Maiques, S, Marina, A, Uriarte, M, Fita, I, Rubio, V. | Deposit date: | 2000-04-28 | Release date: | 2000-07-04 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The 1.5-A Resolution Crystal Structure of the Carbamate Kinase-Like Carbamoyl Phosphate Synthetase from the Hyperthermophilic Archaeon Pyrococcus Furiosus, Bound to Adp, Confirms that This Thermoestable Enzyme is a Carbamate Kinase, and Provides Insights Into Substrate Binding and Stability in Carbamate Kinases J.Mol.Biol., 299, 2000
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5DOU
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![BU of 5dou by Molmil](/molmil-images/mine/5dou) | Crystal Structure of Human Carbamoyl phosphate synthetase I (CPS1), ligand-bound form | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | de Cima, S, Polo, L.M, Fita, I, Rubio, V. | Deposit date: | 2015-09-11 | Release date: | 2015-12-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of human carbamoyl phosphate synthetase: deciphering the on/off switch of human ureagenesis. Sci Rep, 5, 2015
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1OHB
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![BU of 1ohb by Molmil](/molmil-images/mine/1ohb) | Acetylglutamate kinase from Escherichia coli complexed with ADP and sulphate | Descriptor: | ACETATE ION, ACETYLGLUTAMATE KINASE, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Gil-Ortiz, F, Ramon-Maiques, S, Fita, I, Rubio, V. | Deposit date: | 2003-05-23 | Release date: | 2003-07-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Course of Phosphorus in the Reaction of N-Acetyl-L-Glutamate Kinase, Determined from the Structures of Crystalline Complexes, Including a Complex with an Alf(4)(-) Transition State Mimic J.Mol.Biol., 331, 2003
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1OH9
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![BU of 1oh9 by Molmil](/molmil-images/mine/1oh9) | Acetylglutamate kinase from Escherichia coli complexed with MgADP, N-acetyl-L-glutamate and the transition-state mimic AlF4- | Descriptor: | ACETYLGLUTAMATE KINASE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Gil-Ortiz, F, Ramon-Maiques, S, Fita, I, Rubio, V. | Deposit date: | 2003-05-23 | Release date: | 2003-07-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | The Course of Phosphorus in the Reaction of N-Acetyl-L-Glutamate Kinase, Determined from the Structures of Crystalline Complexes, Including a Complex with an Alf(4)(-) Transition State Mimic J.Mol.Biol., 331, 2003
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1OHA
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![BU of 1oha by Molmil](/molmil-images/mine/1oha) | Acetylglutamate kinase from Escherichia coli complexed with MgADP and N-acetyl-L-glutamate | Descriptor: | ACETATE ION, ACETYLGLUTAMATE KINASE, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Gil-Ortiz, F, Ramon-Maiques, S, Fita, I, Rubio, V. | Deposit date: | 2003-05-23 | Release date: | 2003-07-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Course of Phosphorus in the Reaction of N-Acetyl-L-Glutamate Kinase, Determined from the Structures of Crystalline Complexes, Including a Complex with an Alf(4)(-) Transition State Mimic J.Mol.Biol., 331, 2003
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5DY0
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4OZN
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![BU of 4ozn by Molmil](/molmil-images/mine/4ozn) | GlnK2 from Haloferax mediterranei complexed with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Nitrogen regulatory protein P-II, SULFATE ION | Authors: | Palanca, C, Pedro-Roig, L, Llacer, J.L, Camacho, M, Bonete, M.J, Rubio, V. | Deposit date: | 2014-02-17 | Release date: | 2014-07-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The structure of a PII signaling protein from a halophilic archaeon reveals novel traits and high-salt adaptations. Febs J., 281, 2014
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4OZJ
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![BU of 4ozj by Molmil](/molmil-images/mine/4ozj) | GlnK2 from Haloferax mediterranei complexed with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Nitrogen regulatory protein P-II | Authors: | Palanca, C, Pedro-Roig, L, Llacer, J.L, Camacho, M, Bonete, M.J, Rubio, V. | Deposit date: | 2014-02-17 | Release date: | 2014-07-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The structure of a PII signaling protein from a halophilic archaeon reveals novel traits and high-salt adaptations. Febs J., 281, 2014
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4OZL
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![BU of 4ozl by Molmil](/molmil-images/mine/4ozl) | GlnK2 from Haloferax mediterranei complexed with AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Nitrogen regulatory protein P-II, SULFATE ION | Authors: | Palanca, C, Pedro-Roig, L, Llacer, J.L, Camacho, M, Bonete, M.J, Rubio, V. | Deposit date: | 2014-02-17 | Release date: | 2014-07-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.4942 Å) | Cite: | The structure of a PII signaling protein from a halophilic archaeon reveals novel traits and high-salt adaptations. Febs J., 281, 2014
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2J5T
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![BU of 2j5t by Molmil](/molmil-images/mine/2j5t) | Glutamate 5-kinase from Escherichia coli complexed with glutamate | Descriptor: | CHLORIDE ION, GLUTAMATE 5-KINASE, GLUTAMIC ACID, ... | Authors: | Marco-Marin, C, Gil-Ortiz, F, Perez-Arellano, I, Cervera, J, Fita, I, Rubio, V. | Deposit date: | 2006-09-19 | Release date: | 2007-03-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A Novel Two-Domain Architecture within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia Coli Glutamate 5-Kinase. J.Mol.Biol., 367, 2007
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2BRX
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2BTY
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![BU of 2bty by Molmil](/molmil-images/mine/2bty) | Acetylglutamate kinase from Thermotoga maritima complexed with its inhibitor arginine | Descriptor: | ACETYLGLUTAMATE KINASE, ARGININE, N-ACETYL-L-GLUTAMATE, ... | Authors: | Gil-Ortiz, F, Fernandez-Murga, M.L, Fita, I, Rubio, V. | Deposit date: | 2005-06-08 | Release date: | 2005-12-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural Bases of Feed-Back Control of Arginine Biosynthesis, Revealed by the Structure of Two Hexameric N-Acetylglutamate Kinases, from Thermotoga Maritima and Pseudomonas Aeruginosa J.Mol.Biol., 356, 2006
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2BMU
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![BU of 2bmu by Molmil](/molmil-images/mine/2bmu) | UMP KINASE FROM PYROCOCCUS FURIOSUS COMPLEXED WITH ITS SUBSTRATE UMP AND ITS SUBSTRATE ANALOG AMPPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, URIDINE-5'-MONOPHOSPHATE, ... | Authors: | Marco-Marin, C, Gil-Ortiz, F, Rubio, V. | Deposit date: | 2005-03-16 | Release date: | 2005-07-25 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | The Crystal Structure of Pyrococcus Furiosus Ump Kinase Provides Insight Into Catalysis and Regulation in Microbial Pyrimidine Nucleotide Biosynthesis. J.Mol.Biol., 352, 2005
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2WE4
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![BU of 2we4 by Molmil](/molmil-images/mine/2we4) | Carbamate kinase from Enterococcus faecalis bound to a sulfate ion and two water molecules, which mimic the substrate carbamyl phosphate | Descriptor: | CARBAMATE KINASE 1, SULFATE ION | Authors: | Ramon-Maiques, S, Marina, A, Gil-Ortiz, F, Rubio, V. | Deposit date: | 2009-03-27 | Release date: | 2010-03-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Substrate Binding and Catalysis in Carbamate Kinase Ascertained by Crystallographic and Site-Directed Mutagenesis Studies. Movements and Significance of a Unique Globular Subdomain of This Key Enzyme for Fermentative ATP Production in Bacteria. J.Mol.Biol., 397, 2010
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2BRI
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3GL9
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![BU of 3gl9 by Molmil](/molmil-images/mine/3gl9) | The structure of a histidine kinase-response regulator complex sheds light into two-component signaling and reveals a novel cis autophosphorylation mechanism | Descriptor: | MAGNESIUM ION, Response regulator, SULFATE ION | Authors: | Casino, P, Rubio, V, Marina, A. | Deposit date: | 2009-03-11 | Release date: | 2009-10-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Insight into Partner Specificity and Phosphoryl Transfer in Two-Component Signal Transduction Cell(Cambridge,Mass.), 139, 2009
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