6PZN
 
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6PZM
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6WPR
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6NRP
 | | Putative short-chain dehydrogenase/reductase (SDR) from Acinetobacter baumannii | | Descriptor: | 3-oxoacyl-ACP reductase FabG | | Authors: | Cross, E.M, Smith, K.M, Shaw, K.I, Aragao, D, Forwood, J.K. | | Deposit date: | 2019-01-23 | | Release date: | 2019-02-27 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Insights into Acinetobacter baumannii fatty acid synthesis 3-oxoacyl-ACP reductases.
Sci Rep, 11, 2021
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8F2Q
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8SUD
 | | JC Polyomavirus LTA NLS bound to importin alpha 2 | | Descriptor: | Importin subunit alpha-1, Large T antigen | | Authors: | Cross, E.M, Forwood, J.K, Alvisi, G. | | Deposit date: | 2023-05-12 | | Release date: | 2024-02-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
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8TUU
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8TUV
 | | Merkel Cell Polyomavirus LTA NLSm bound to importin alpha 2 | | Descriptor: | 30S ribosomal protein S11, Importin subunit alpha-1, SER-ARG-LYS-ARG-LYS-PHE | | Authors: | Cross, E.M, Forwood, J.K, Alvisi, G. | | Deposit date: | 2023-08-17 | | Release date: | 2024-02-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
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8TUT
 | | Merkel Cell Polyomavirus LTA NLSct bound to importin alpha 2 | | Descriptor: | Importin subunit alpha-1, PRO-PRO-LYS-PRO-LYS-LYS-ASN-ARG-GLU | | Authors: | Cross, E.M, Forwood, J.K, Alvisi, G. | | Deposit date: | 2023-08-17 | | Release date: | 2024-02-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
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8QXX
 | | HCMV DNA polymerase processivity factor UL44 phosphorylated NLS 410-433 bound to mouse importin alpha 2 | | Descriptor: | DNA polymerase processivity factor, Importin subunit alpha-1 | | Authors: | Cross, E.M, Marin, O, Ariawan, D, Aragao, D, Cozza, G, Di Iorio, E, Forwood, J.K, Alvisi, G. | | Deposit date: | 2023-10-25 | | Release date: | 2023-11-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44.
Febs Lett., 598, 2024
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8QXW
 | | HCMV DNA polymerase processivity factor UL44 unphosphorylated NLS 410-433 bound to mouse importin alpha 2 | | Descriptor: | DNA polymerase processivity factor, Importin subunit alpha-1 | | Authors: | Cross, E.M, Marin, O, Ariawan, D, Aragao, D, Cozza, G, Di Iorio, E, Forwood, J.K, Alvisi, G. | | Deposit date: | 2023-10-25 | | Release date: | 2023-11-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44.
Febs Lett., 598, 2024
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8Q8K
 | | KI Polyomavirus LTA NLS bound to importin alpha 2 | | Descriptor: | Importin subunit alpha-1, Large T antigen | | Authors: | Cross, E.M, Forwood, J.K, Alvisi, G. | | Deposit date: | 2023-08-18 | | Release date: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
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8TUR
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6UUV
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6UUT
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1SVS
 | | Structure of the K180P mutant of Gi alpha subunit bound to GppNHp. | | Descriptor: | Guanine nucleotide-binding protein G(i), alpha-1 subunit, MAGNESIUM ION, ... | | Authors: | Thomas, C.J, Du, X, Li, P, Wang, Y, Ross, E.M, Sprang, S.R. | | Deposit date: | 2004-03-29 | | Release date: | 2004-06-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein {alpha}-subunit.
Proc.Natl.Acad.Sci.USA, 101, 2004
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1SVK
 | | Structure of the K180P mutant of Gi alpha subunit bound to AlF4 and GDP | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ... | | Authors: | Thomas, C.J, Du, X, Li, P, Wang, Y, Ross, E.M, Sprang, S.R. | | Deposit date: | 2004-03-29 | | Release date: | 2004-06-01 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein {alpha}-subunit.
Proc.Natl.Acad.Sci.USA, 101, 2004
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6BVV
 | | Nipah virus W protein C-terminus in complex with Importin alpha 3 | | Descriptor: | Importin subunit alpha-3, Protein W | | Authors: | Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | | Deposit date: | 2017-12-13 | | Release date: | 2018-07-04 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
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6BVT
 | | Importin alpha 1 in cargo free state | | Descriptor: | Importin subunit alpha-1 | | Authors: | Smith, K.M, Tsimablyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | | Deposit date: | 2017-12-13 | | Release date: | 2018-07-04 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
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6BW1
 | | Hendra virus W protein C-terminus in complex with Importin alpha 1 | | Descriptor: | Importin subunit alpha-1, Protein W | | Authors: | Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | | Deposit date: | 2017-12-14 | | Release date: | 2018-07-04 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
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6BW0
 | | Nipah virus W protein C-terminus in complex with Importin alpha 1 | | Descriptor: | Importin subunit alpha-1, Protein W | | Authors: | Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | | Deposit date: | 2017-12-14 | | Release date: | 2018-07-04 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
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6BWB
 | | Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 3 | | Descriptor: | Importin subunit alpha-3, Protein W | | Authors: | Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | | Deposit date: | 2017-12-14 | | Release date: | 2018-07-04 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
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6BW9
 | | Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 1 | | Descriptor: | Importin subunit alpha-3, Protein W | | Authors: | Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | | Deposit date: | 2017-12-14 | | Release date: | 2018-07-04 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
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6BWA
 | | Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 2 | | Descriptor: | Importin subunit alpha-3, Protein W | | Authors: | Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | | Deposit date: | 2017-12-14 | | Release date: | 2018-07-04 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
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6BVZ
 | | Importin alpha 3 in cargo free state | | Descriptor: | Importin subunit alpha-3 | | Authors: | Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | | Deposit date: | 2017-12-14 | | Release date: | 2018-07-04 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
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