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PDB: 24 件

2SAM
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STRUCTURE OF THE PROTEASE FROM SIMIAN IMMUNODEFICIENCY VIRUS: COMPLEX WITH AN IRREVERSIBLE NON-PEPTIDE INHIBITOR
分子名称: 3-(4-NITRO-PHENOXY)-PROPAN-1-OL, SIV PROTEASE
著者Rose, R.B, Rose, J.R, Salto, R, Craik, C.S, Stroud, R.M.
登録日1994-07-08
公開日1994-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the protease from simian immunodeficiency virus: complex with an irreversible nonpeptide inhibitor.
Biochemistry, 32, 1993
1AZ5
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UNLIGANDED SIV PROTEASE STRUCTURE IN AN "OPEN" CONFORMATION
分子名称: SIV PROTEASE
著者Rose, R.B, Craik, C.S, Stroud, R.M.
登録日1997-11-25
公開日1998-05-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Domain flexibility in retroviral proteases: structural implications for drug resistant mutations.
Biochemistry, 37, 1998
1G39
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WILD-TYPE HNF-1ALPHA DIMERIZATION DOMAIN
分子名称: HEPATOCYTE NUCLEAR FACTOR 1-ALPHA
著者Rose, R.B, Endrizzi, J.A, Cronk, J.D, Holton, J, Alber, T.
登録日2000-10-23
公開日2001-01-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献High-resolution structure of the HNF-1alpha dimerization domain.
Biochemistry, 39, 2000
1G2Z
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DIMERIZATION DOMAIN OF HNF-1ALPHA WITH A LEU 13 SELENOMETHIONINE SUBSTITUTION
分子名称: HEPATOCYTE NUCLEAR FACTOR 1-ALPHA
著者Rose, R.B, Endrizzi, J.A, Cronk, J.D, Holton, J, Alber, T.
登録日2000-10-23
公開日2001-01-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献High-resolution structure of the HNF-1alpha dimerization domain.
Biochemistry, 39, 2000
1G2Y
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HNF-1ALPHA DIMERIZATION DOMAIN, WITH SELENOMETHIONINE SUBSTITUED AT LEU 12
分子名称: HEPATOCYTE NUCLEAR FACTOR 1-ALPHA
著者Rose, R.B, Endrizzi, J.A, Cronk, J.D, Holton, J, Alber, T.
登録日2000-10-23
公開日2001-01-17
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献High-resolution structure of the HNF-1alpha dimerization domain.
Biochemistry, 39, 2000
1RU0
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Crystal structure of DCoH2, a paralog of DCoH, the Dimerization Cofactor of HNF-1
分子名称: DcoH-like protein DCoHm
著者Rose, R.B, Pullen, K.E, Bayle, J.H, Crabtree, G.R, Alber, T.
登録日2003-12-10
公開日2004-10-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Biochemical and structural basis for partially redundant enzymatic and transcriptional functions of DCoH and DCoH2
Biochemistry, 43, 2004
2QL2
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Crystal Structure of the basic-helix-loop-helix domains of the heterodimer E47/NeuroD1 bound to DNA
分子名称: DNA (5'-D(*DAP*DGP*DGP*DAP*DCP*DCP*DAP*DGP*DAP*DTP*DGP*DGP*DCP*DCP*DTP*DA)-3'), DNA (5'-D(*DTP*DAP*DGP*DGP*DCP*DCP*DAP*DTP*DCP*DTP*DGP*DGP*DTP*DCP*DCP*DT)-3'), Neurogenic differentiation factor 1, ...
著者Rose, R.B, Longo, A, Guanga, G.P.
登録日2007-07-12
公開日2008-11-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition.
Biochemistry, 47, 2008
1F93
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CRYSTAL STRUCTURE OF A COMPLEX BETWEEN THE DIMERIZATION DOMAIN OF HNF-1 ALPHA AND THE COACTIVATOR DCOH
分子名称: DIMERIZATION COFACTOR OF HEPATOCYTE NUCLEAR FACTOR 1-ALPHA, HEPATOCYTE NUCLEAR FACTOR 1-ALPHA
著者Rose, R.B, Bayle, J.H, Endrizzi, J.A, Cronk, J.D, Crabtree, G.R, Alber, T.
登録日2000-07-06
公開日2000-09-20
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of dimerization, coactivator recognition and MODY3 mutations in HNF-1alpha.
Nat.Struct.Biol., 7, 2000
1YTG
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SIV PROTEASE CRYSTALLIZED WITH PEPTIDE PRODUCT
分子名称: HIV PROTEASE, PEPTIDE PRODUCT
著者Rose, R.B, Craik, C.S, Douglas, N.L, Stroud, R.M.
登録日1996-08-01
公開日1997-03-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Three-dimensional structures of HIV-1 and SIV protease product complexes.
Biochemistry, 35, 1996
1YTJ
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SIV PROTEASE CRYSTALLIZED WITH PEPTIDE PRODUCT
分子名称: PEPTIDE PRODUCT, SIV PROTEASE
著者Rose, R.B, Craik, C.S, Douglas, N.L, Stroud, R.M.
登録日1996-08-01
公開日1997-03-12
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Three-dimensional structures of HIV-1 and SIV protease product complexes.
Biochemistry, 35, 1996
1YTH
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SIV PROTEASE CRYSTALLIZED WITH PEPTIDE PRODUCT
分子名称: HIV PROTEASE, PEPTIDE PRODUCT
著者Rose, R.B, Craik, C.S, Douglas, N.L, Stroud, R.M.
登録日1996-08-01
公開日1997-03-12
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Three-dimensional structures of HIV-1 and SIV protease product complexes.
Biochemistry, 35, 1996
1YTI
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SIV PROTEASE CRYSTALLIZED WITH PEPTIDE PRODUCT
分子名称: PEPTIDE PRODUCT, SIV PROTEASE
著者Rose, R.B, Craik, C.S, Douglas, N.L, Stroud, R.M.
登録日1996-08-01
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Three-dimensional structures of HIV-1 and SIV protease product complexes.
Biochemistry, 35, 1996
4WIL
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Crystal structure of DCoH2 S51T
分子名称: Pterin-4-alpha-carbinolamine dehydratase 2
著者Wang, D, Rose, R.B.
登録日2014-09-26
公開日2014-12-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Interactions with the Bifunctional Interface of the Transcriptional Coactivator DCoH1 Are Kinetically Regulated.
J.Biol.Chem., 290, 2015
3HXA
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Crystal Structure of DCoH1Thr51Ser
分子名称: GLYCEROL, Pterin-4-alpha-carbinolamine dehydratase, SULFATE ION
著者Rho, H.Y, Jones, C.N, Rose, R.B.
登録日2009-06-20
公開日2010-08-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of DCoH1Thr51Ser
To be Published
7KBL
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Biotin Carboxylase domain of Thermophilic 2-Oxoglutarate Carboxylase bound to Bicarbonate
分子名称: 2-oxoglutarate carboxylase small subunit, BICARBONATE ION
著者Buhrman, G.K, Rose, R.B, Enriquez, P, Truong, V.
登録日2020-10-02
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure, Function, and Thermal Adaptation of the Biotin Carboxylase Domain Dimer from Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase.
Biochemistry, 60, 2021
7KC7
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Biotin Carboxylase domain of Thermophilic 2-Oxoglutarate Carboxylase bound to ADP without Magnesium with disordered phosphate tail
分子名称: 2-oxoglutarate carboxylase small subunit, ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION
著者Buhrman, G.K, Rose, R.B, Enriquez, P, Truong, V.
登録日2020-10-05
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure, Function, and Thermal Adaptation of the Biotin Carboxylase Domain Dimer from Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase.
Biochemistry, 60, 2021
7KCT
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Crystal Structure of the Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase (OGC) Biotin Carboxylase (BC) Domain Dimer in Complex with Adenosine 5'-Diphosphate Magnesium Salt (MgADP), Adenosine 5'-Diphosphate (ADP, and Bicarbonate Anion (Hydrogen Carbonate/HCO3-)
分子名称: 2-oxoglutarate carboxylase small subunit, ADENOSINE-5'-DIPHOSPHATE, BICARBONATE ION, ...
著者Buhrman, G.K, Rose, R.B, Enriquez, P, Truong, V.
登録日2020-10-07
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structure, Function, and Thermal Adaptation of the Biotin Carboxylase Domain Dimer from Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase.
Biochemistry, 60, 2021
7LHY
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Caenorhabditis elegans SWSN-4 (SMARCA4-BRG1) ATPase Bromodomain in complex with a modified histone H3, N6-epsilon-acetyl-L-lysine 14 (H3K14ac) polypeptide
分子名称: H3(7-20)K14ac, SWI/SNF nucleosome remodeling complex component
著者Enriquez, P, Rose, R.B.
登録日2021-01-26
公開日2021-09-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Binding specificity and function of the SWI/SNF subunit SMARCA4 bromodomain interaction with acetylated histone H3K14.
J.Biol.Chem., 297, 2021
4EOT
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Crystal structure of the MafA homodimer bound to the consensus MARE
分子名称: 5'-D(*CP*CP*CP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP*GP*CP*AP*CP*CP*G)-3', 5'-D(*CP*CP*GP*GP*TP*GP*CP*TP*GP*AP*GP*TP*CP*AP*GP*CP*AP*GP*G)-3', SULFATE ION, ...
著者Lu, X, Guanga, G, Wan, C, Rose, R.B.
登録日2012-04-15
公開日2012-11-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.855 Å)
主引用文献A Novel DNA Binding Mechanism for maf Basic Region-Leucine Zipper Factors Inferred from a MafA-DNA Complex Structure and Binding Specificities.
Biochemistry, 51, 2012
2H1K
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Crystal structure of the Pdx1 homeodomain in complex with DNA
分子名称: 15-mer DNA, Pancreatic and duodenal homeobox 1
著者Longo, A, Guanga, G.P, Rose, R.B.
登録日2006-05-16
公開日2007-03-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural basis for induced fit mechanisms in DNA recognition by the pdx1 homeodomain
Biochemistry, 46, 2007
1KGB
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structure of ground-state bacteriorhodopsin
分子名称: 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, RETINAL, bacteriorhodopsin
著者Facciotti, M.T, Rouhani, S, Burkard, F.T, Betancourt, F.M, Downing, K.H, Rose, R.B, McDermott, G, Glaeser, R.M.
登録日2001-11-26
公開日2001-12-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of an early intermediate in the M-state phase of the bacteriorhodopsin photocycle.
Biophys.J., 81, 2001
1KG8
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X-ray structure of an early-M intermediate of bacteriorhodopsin
分子名称: 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, RETINAL, bacteriorhodopsin
著者Facciotti, M.T, Rouhani, S, Burkard, F.T, Betancourt, F.M, Downing, K.H, Rose, R.B, McDermott, G, Glaeser, R.M.
登録日2001-11-26
公開日2001-12-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of an early intermediate in the M-state phase of the bacteriorhodopsin photocycle.
Biophys.J., 81, 2001
1KG9
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Structure of a "mock-trapped" early-M intermediate of bacteriorhosopsin
分子名称: 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, RETINAL, bacteriorhodopsin
著者Facciotti, M.T, Rouhani, S, Burkard, F.T, Betancourt, F.M, Downing, K.H, Rose, R.B, McDermott, G, Glaeser, R.M.
登録日2001-11-26
公開日2001-12-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structure of an early intermediate in the M-state phase of the bacteriorhodopsin photocycle.
Biophys.J., 81, 2001
1W9G
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Structure of ERH (Enhencer of Rudimentary Gene)
分子名称: ENHANCER OF RUDIMENTARY HOMOLOG
著者Wan, C, Tempel, W, Liu, Z, Wang, B.-C, Rose, R.B.
登録日2004-10-13
公開日2005-04-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the Conserved Transcriptional Repressor Enhancer of Rudimentary Homolog
Biochemistry, 44, 2005

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