2BNX
 
 | | Crystal structure of the dimeric regulatory domain of mouse diaphaneous-related formin (DRF), mDia1 | | Descriptor: | CHLORIDE ION, DIAPHANOUS PROTEIN HOMOLOG 1 | | Authors: | Otomo, T, Otomo, C, Tomchick, D.R, Machius, M, Rosen, M.K. | | Deposit date: | 2005-04-05 | | Release date: | 2005-06-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Basis of Rho Gtpase-Mediated Activation of the Formin Mdia1
Mol.Cell, 18, 2005
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1FKT
 | | SOLUTION STRUCTURE OF FKBP, A ROTAMASE ENZYME AND RECEPTOR FOR FK506 AND RAPAMYCIN | | Descriptor: | FK506 AND RAPAMYCIN-BINDING PROTEIN | | Authors: | Michnick, S.W, Rosen, M.K, Wandless, T.J, Karplus, M, Schreiber, S.L. | | Deposit date: | 1992-03-05 | | Release date: | 1994-01-31 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin.
Science, 252, 1991
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1FKR
 | | SOLUTION STRUCTURE OF FKBP, A ROTAMASE ENZYME AND RECEPTOR FOR FK506 AND RAPAMYCIN | | Descriptor: | FK506 AND RAPAMYCIN-BINDING PROTEIN | | Authors: | Michnick, S.W, Rosen, M.K, Wandless, T.J, Karplus, M, Schreiber, S.L. | | Deposit date: | 1992-03-05 | | Release date: | 1994-01-31 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin.
Science, 252, 1991
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1UHG
 | | Crystal Structure of S-Ovalbumin At 1.9 Angstrom Resolution | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ovalbumin, ... | | Authors: | Yamasaki, M, Takahashi, N, Hirose, M. | | Deposit date: | 2003-07-03 | | Release date: | 2003-07-22 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal Structure of S-ovalbumin as a Non-loop-inserted Thermostabilized Serpin Form
J.Biol.Chem., 278, 2003
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2JRE
 | | C60-1, a PDZ domain designed using statistical coupling analysis | | Descriptor: | C60-1 PDZ domain peptide | | Authors: | Larson, C, Stiffler, M, Li, P, Rosen, M, MacBeath, G, Ranganathan, R. | | Deposit date: | 2007-06-25 | | Release date: | 2008-07-01 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | C60-1, a PDZ domain designed using statistical coupling analysis
To be Published
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1ZZV
 | | Solution NMR Structure of the Periplasmic Signaling Domain of the Outer Membrane Iron Transporter FecA from Escherichia coli. | | Descriptor: | Iron(III) dicitrate transport protein fecA | | Authors: | Ferguson, A.D, Amezcua, C.A, Chelliah, Y, Rosen, M.K, Deisenhofer, J. | | Deposit date: | 2005-06-14 | | Release date: | 2006-09-26 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Signal transduction pathway of TonB-dependent transporters.
Proc.Natl.Acad.Sci.Usa, 2, 2006
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2A02
 | | Solution NMR Structure of the Periplasmic Signaling Domain of the Outer Membrane Iron Transporter PupA from Pseudomonas putida. | | Descriptor: | Ferric-pseudobactin 358 receptor | | Authors: | Ferguson, A.D, Amezcua, C.A, Chelliah, Y, Rosen, M.K, Deisenhofer, J. | | Deposit date: | 2005-06-15 | | Release date: | 2006-09-26 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Signal transduction pathway of TonB-dependent transporters.
Proc.Natl.Acad.Sci.Usa, 2, 2006
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4M63
 | | Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ... | | Authors: | Tomchick, D.R, Zahm, J.A, Rosen, M.K. | | Deposit date: | 2013-08-08 | | Release date: | 2013-10-23 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.748 Å) | | Cite: | The Bacterial Effector VopL Organizes Actin into Filament-like Structures.
Cell(Cambridge,Mass.), 155, 2013
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1OVT
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1JBY
 | | CRYSTAL STRUCTURE ANALYSIS OF A DUAL-WAVELENGTH EMISSION GREEN FLUORESCENT PROTEIN VARIANT AT LOW PH | | Descriptor: | GREEN FLUORESCENT PROTEIN | | Authors: | Hanson, G.T, McAnaney, T.B, Park, E.S, Rendell, M.E.P, Yarbrough, D.K, Chu, S, Xi, L, Boxer, S.G, Montrose, M.H, Remington, S.J. | | Deposit date: | 2001-06-07 | | Release date: | 2003-01-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Green Fluorescent Protein Variants as Ratiometric Dual Emission pH Sensors. 1. Structural Characterization and Preliminary Application.
Biochemistry, 41, 2002
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1T84
 | | Solution structure of the Wiskott-Aldrich Syndrome Protein (WASP) autoinhibited core domain complexed with (S)-wiskostatin, a small molecule inhibitor | | Descriptor: | (2S)-1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL, Wiskott-Aldrich syndrome protein | | Authors: | Peterson, J.R, Bickford, L.C, Morgan, D, Kim, A.S, Ouerfelli, O, Kirschner, M.W, Rosen, M.K. | | Deposit date: | 2004-05-11 | | Release date: | 2004-07-13 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation.
Nat.Struct.Mol.Biol., 11, 2004
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1JBZ
 | | CRYSTAL STRUCTURE ANALYSIS OF A DUAL-WAVELENGTH EMISSION GREEN FLUORESCENT PROTEIN VARIANT AT HIGH PH | | Descriptor: | 1,2-ETHANEDIOL, GREEN FLUORESCENT PROTEIN, MAGNESIUM ION | | Authors: | Hanson, G.T, McAnaney, T.B, Park, E.S, Rendell, M.E.P, Yarbrough, D.K, Chu, S, Xi, L, Boxer, S.G, Montrose, M.H, Remington, S.J. | | Deposit date: | 2001-06-07 | | Release date: | 2003-01-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Green Fluorescent Protein Variants as Ratiometric Dual Emission pH Sensors. 1. Structural Characterization and Preliminary Application.
Biochemistry, 41, 2002
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3SEO
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2ZQ3
 | | The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.6 angstroms resolution | | Descriptor: | Lysozyme C, SODIUM ION | | Authors: | Aibara, S, Suzuki, A, Kidera, A, Shibata, K, Hirose, M. | | Deposit date: | 2008-08-03 | | Release date: | 2008-09-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.5 angstroms resolution
To be Published
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2ZQ4
 | | The crystal structure of the orthorhombic form of hen egg white lysozyme at 2.0 angstroms resolution | | Descriptor: | Lysozyme C | | Authors: | Aibara, S, Suzuki, A, Kidera, A, Shibata, K, Yamane, T, Hirose, M. | | Deposit date: | 2008-08-03 | | Release date: | 2008-09-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.5 angstroms resolution
To be Published
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3Q0W
 | | ETHR From mycobacterium tuberculosis in complex with compound BDM33066 | | Descriptor: | (2S)-2-amino-3-methyl-1-{4-[3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}butan-1-one, GLYCEROL, HTH-type transcriptional regulator EthR | | Authors: | Flipo, M, Desrose, M, Dirie, B, Carette, X, Leroux, F, Lens, Z, Rucktooa, P, Piveteau, C, Demirkaya, F, Locht, C, Villeret, V, Christophe, T, Jeon, H.K, Brodin, P, Deprez, B, Baulard, A, Willand, N. | | Deposit date: | 2010-12-16 | | Release date: | 2011-12-21 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands.
Nucleic Acids Res., 40, 2012
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1NFT
 | | OVOTRANSFERRIN, N-TERMINAL LOBE, IRON LOADED OPEN FORM | | Descriptor: | FE (III) ION, NITRILOTRIACETIC ACID, PROTEIN (OVOTRANSFERRIN), ... | | Authors: | Mizutani, K, Yamashita, H, Kurokawa, H, Mikami, B, Hirose, M. | | Deposit date: | 1999-01-07 | | Release date: | 1999-01-13 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Alternative structural state of transferrin. The crystallographic analysis of iron-loaded but domain-opened ovotransferrin N-lobe.
J.Biol.Chem., 274, 1999
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3O8H
 | | EthR from Mycobacterium tuberculosis in complex with compound BDM14950 | | Descriptor: | 4-iodo-N-[(1-{2-oxo-2-[4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)piperidin-1-yl]ethyl}-1H-1,2,3-triazol-4-yl)methyl]benzenesulfonamide, Transcriptional Regulatory Repressor protein (TETR-Family) EthR | | Authors: | Willand, N, Desroses, M, Toto, P, Diri, B, Lens, Z, Villeret, V, Rucktooa, P, Locht, C, Baulard, A, Deprez, B. | | Deposit date: | 2010-08-03 | | Release date: | 2010-09-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Exploring drug target flexibility using in situ click chemistry: application to a mycobacterial transcriptional regulator.
Acs Chem.Biol., 5, 2010
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1SRL
 | | 1H AND 15N ASSIGNMENTS AND SECONDARY STRUCTURE OF THE SRC SH3 DOMAIN | | Descriptor: | SRC TYROSINE KINASE SH3 DOMAIN | | Authors: | Yu, H, Rosen, M.K, Shin, T.B, Seidel-Dugan, C, Brugge, J.S, Schreiber, S.L. | | Deposit date: | 1994-03-07 | | Release date: | 1994-05-31 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | 1H and 15N assignments and secondary structure of the Src SH3 domain.
FEBS Lett., 324, 1993
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1IEJ
 | | OVOTRANSFERRIN, N-TERMINAL LOBE, HOLO FORM, AT 1.65 A RESOLUTION | | Descriptor: | CARBONATE ION, FE (III) ION, OVOTRANSFERRIN | | Authors: | Mizutani, K, Mikami, B, Hirose, M. | | Deposit date: | 2001-04-10 | | Release date: | 2001-06-20 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Domain closure mechanism in transferrins: new viewpoints about the hinge structure and motion as deduced from high resolution crystal structures of ovotransferrin N-lobe.
J.Mol.Biol., 309, 2001
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1IQ7
 | | Ovotransferrin, C-Terminal Lobe, Apo Form | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Ovotransferrin, SULFATE ION | | Authors: | Mizutani, K, Muralidhara, B.K, Yamashita, H, Tabata, S, Mikami, B, Hirose, M. | | Deposit date: | 2001-07-06 | | Release date: | 2001-11-28 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Anion-mediated Fe3+ release mechanism in ovotransferrin C-lobe: a structurally identified SO4(2-) binding site and its implications for the kinetic pathway.
J.Biol.Chem., 276, 2001
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1SRM
 | | 1H AND 15N ASSIGNMENTS AND SECONDARY STRUCTURE OF THE SRC SH3 DOMAIN | | Descriptor: | SRC TYROSINE KINASE SH3 DOMAIN | | Authors: | Yu, H, Rosen, M.K, Shin, T.B, Seidel-Dugan, C, Brugge, J.S, Schreiber, S.L. | | Deposit date: | 1994-03-07 | | Release date: | 1994-05-31 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | 1H and 15N assignments and secondary structure of the Src SH3 domain.
FEBS Lett., 324, 1993
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1TFA
 | | OVOTRANSFERRIN, N-TERMINAL LOBE, APO FORM | | Descriptor: | PROTEIN (OVOTRANSFERRIN), SULFATE ION | | Authors: | Mizutani, K, Yamashita, H, Mikami, B, Hirose, M. | | Deposit date: | 1999-01-07 | | Release date: | 1999-01-13 | | Last modified: | 2018-04-04 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Alternative structural state of transferrin. The crystallographic analysis of iron-loaded but domain-opened ovotransferrin N-lobe.
J.Biol.Chem., 274, 1999
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1VDP
 | | The crystal structure of the monoclinic form of hen egg white lysozyme at 1.7 angstroms resolution in space | | Descriptor: | Lysozyme C | | Authors: | Aibara, S, Suzuki, A, Kidera, A, Shibata, K, Yamane, T, DeLucas, L.J, Hirose, M. | | Deposit date: | 2004-03-24 | | Release date: | 2004-04-13 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The crystal structure of the monoclinic form of hen egg white lysozyme at 1.7 angstroms resolution in space
to be published
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1EJ5
 | | SOLUTION STRUCTURE OF THE AUTOINHIBITED CONFORMATION OF WASP | | Descriptor: | WISKOTT-ALDRICH SYNDROME PROTEIN | | Authors: | Kim, A.S, Kakalis, L.T, Abdul-Manan, N, Liu, G.A, Rosen, M.K. | | Deposit date: | 2000-02-29 | | Release date: | 2000-04-05 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein.
Nature, 404, 2000
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