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PDB: 217 results

2OCJ
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Human p53 core domain in the absence of DNA
Descriptor: P53 TUMOR SUPPRESSOR, ZINC ION
Authors:Wang, Y, Rosengarth, A, Luecke, H.
Deposit date:2006-12-20
Release date:2007-03-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the human p53 core domain in the absence of DNA.
Acta Crystallogr.,Sect.D, 63, 2007
2G9O
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Solution structure of the apo form of the third metal-binding domain of ATP7A protein (Menkes Disease protein)
Descriptor: Copper-transporting ATPase 1
Authors:Banci, L, Bertini, I, Cantini, F, DellaMalva, N, Rosato, A, Herrmann, T, Wuthrich, K, Structural Proteomics in Europe (SPINE)
Deposit date:2006-03-07
Release date:2006-08-01
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure and intermolecular interactions of the third metal-binding domain of ATP7A, the Menkes disease protein.
J.Biol.Chem., 281, 2006
7KTX
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BU of 7ktx by Molmil
Cryo-EM structure of Saccharomyces cerevisiae ER membrane protein complex bound to a Fab in DDM detergent
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ER membrane protein complex subunit 1, ER membrane protein complex subunit 2, ...
Authors:Miller-Vedam, L.E, Schirle Oakdale, N.S, Braeuning, B, Boydston, E.A, Sevillano, N, Popova, K.D, Bonnar, J.L, Shurtleff, M.J, Prabu, J.R, Stroud, R.M, Craik, C.S, Schulman, B.A, Weissman, J.S, Frost, A.
Deposit date:2020-11-24
Release date:2020-12-02
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.
Elife, 9, 2020
7KOD
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Cryo-EM structure of heavy chain mouse apoferritin
Descriptor: Ferritin heavy chain
Authors:Sun, M, Azumaya, C, Tse, E, Frost, A, Southworth, D, Verba, K.A, Cheng, Y, Agard, D.A.
Deposit date:2020-11-08
Release date:2020-12-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (1.655 Å)
Cite:Practical considerations for using K3 cameras in CDS mode for high-resolution and high-throughput single particle cryo-EM.
J.Struct.Biol., 213, 2021
2FZH
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New Insights into Dihydrofolate Reductase Interactions: Analysis of Pneumocystis carinii and Mouse DHFR Complexes with NADPH and Two Highly Potent Trimethoprim Derivatives
Descriptor: 2,4-DIAMINO-5-[2-METHOXY-5-(4-CARBOXYBUTYLOXY)BENZYL]PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Cody, V, Pace, J, Chisum, K, Rosowsky, A.
Deposit date:2006-02-09
Release date:2006-12-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions.
Proteins, 65, 2006
2GA7
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Solution structure of the copper(I) form of the third metal-binding domain of ATP7A protein (menkes disease protein)
Descriptor: COPPER (I) ION, Copper-transporting ATPase 1
Authors:Banci, L, Bertini, I, Cantini, F, DellaMalva, N, Rosato, A, Herrmann, T, Wuthrich, K, Structural Proteomics in Europe (SPINE)
Deposit date:2006-03-08
Release date:2006-08-01
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure and intermolecular interactions of the third metal-binding domain of ATP7A, the Menkes disease protein.
J.Biol.Chem., 281, 2006
2PE5
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BU of 2pe5 by Molmil
Crystal Structure of the Lac Repressor bound to ONPG in repressed state
Descriptor: 2-nitrophenyl beta-D-galactopyranoside, DNA (5'-D(*DAP*DAP*DTP*DTP*DGP*DTP*DGP*DAP*DGP*DCP*DGP*DCP*DTP*DCP*DAP*DCP*DAP*DAP*DTP*DT)-3'), Lactose operon repressor
Authors:Daber, R, Stayrook, S.E, Rosenberg, A, Lewis, M.
Deposit date:2007-04-02
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural analysis of lac repressor bound to allosteric effectors
J.Mol.Biol., 370, 2007
2FZI
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New Insights into DHFR Interactions: Analysis of Pneumocystis carinii and Mouse DHFR Complexes with NADPH and Two Highly Potent Trimethoprim Derivatives
Descriptor: 2,4-DIAMINO-5-[3',4'-DIMETHOXY-5'-(5-CARBOXYL-1-PENTYNYL)]BENZYL PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Cody, V, Pace, J, Chisum, K, Rosowsky, A.
Deposit date:2006-02-09
Release date:2006-12-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions.
Proteins, 65, 2006
2FZJ
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New Insights into DHFR Interactions: Analysis of Pneumocystis carinii and Mouse DHFR Complexes with NADPH and Two Highly Potent Trimethoprim Derivatives
Descriptor: 2,4-DIAMINO-5-[3',4'-DIMETHOXY-5'-(5-CARBOXYL-1-PENTYNYL)]BENZYL PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Cody, V, Pace, J, Chisum, K, Rosowsky, A.
Deposit date:2006-02-09
Release date:2006-12-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions.
Proteins, 65, 2006
7KRA
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Cryo-EM structure of Saccharomyces cerevisiae ER membrane protein complex bound to Fab-DH4 in lipid nanodiscs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ER membrane protein complex subunit 1, ER membrane protein complex subunit 2, ...
Authors:Miller-Vedam, L.E, Schirle Oakdale, N.S, Braeuning, B, Boydston, E.A, Sevillano, N, Popova, K.D, Bonnar, J.L, Shurtleff, M.J, Prabu, J.R, Stroud, R.M, Craik, C.S, Schulman, B.A, Weissman, J.S, Frost, A.
Deposit date:2020-11-19
Release date:2020-12-02
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.
Elife, 9, 2020
7L70
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BU of 7l70 by Molmil
The eukaryotic translation initiation factor 2B from Homo sapiens in its apo form
Descriptor: Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, ...
Authors:Wang, L, Schoof, M, Lawrence, R, Boone, M, Frost, A, Walter, P.
Deposit date:2020-12-24
Release date:2021-03-24
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:eIF2B conformation and assembly state regulates the integrated stress response.
Elife, 10, 2021
2JK5
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Potassium Channel KcsA in complex with Tetrabutylammonium in high K
Descriptor: (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, ...
Authors:Lenaeus, M.J, Focia, P.J, Wagner, T, Gross, A.
Deposit date:2008-08-15
Release date:2009-11-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site.
Biochemistry, 53, 2014
2OR8
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Tim-1
Descriptor: ACETATE ION, Hepatitis A virus cellular receptor 1 homolog
Authors:Santiago, C, Ballesteros, A, Kaplan, G.G, Casasnovas, J.M.
Deposit date:2007-02-02
Release date:2007-04-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of T Cell Immunoglobulin Mucin Receptors 1 and 2 Reveal Mechanisms for Regulation of Immune Responses by the TIM Receptor Family.
Immunity, 26, 2007
2P7C
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BU of 2p7c by Molmil
Solution structure of the bacillus licheniformis BlaI monomeric form in complex with the blaP half-operator.
Descriptor: Penicillinase repressor, Strand 1 of Twelve base-pair DNA, Strand 2 of Twelve base-pair DNA
Authors:Boudet, J, Duval, V, Van Melckebeke, H, Blackledge, M, Amoroso, A, Joris, B, Simorre, J.-P.
Deposit date:2007-03-20
Release date:2007-06-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Conformational and thermodynamic changes of the repressor/DNA operator complex upon monomerization shed new light on regulation mechanisms of bacterial resistance against beta-lactam antibiotics.
Nucleic Acids Res., 35, 2007
2OR7
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Tim-2
Descriptor: ACETATE ION, T-cell immunoglobulin and mucin domain-containing protein 2
Authors:Santiago, C, Ballesteros, A, Kaplan, G.G, Casasnovas, J.M.
Deposit date:2007-02-02
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structures of T Cell Immunoglobulin Mucin Receptors 1 and 2 Reveal Mechanisms for Regulation of Immune Responses by the TIM Receptor Family.
Immunity, 26, 2007
2GGP
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BU of 2ggp by Molmil
Solution structure of the Atx1-Cu(I)-Ccc2a complex
Descriptor: COPPER (I) ION, Metal homeostasis factor ATX1, Probable copper-transporting ATPase
Authors:Banci, L, Bertini, I, Cantini, F, Felli, I.C, Gonnelli, L, Hadjiliadis, N, Pierattelli, R, Rosato, A, Voulgaris, P, Structural Proteomics in Europe (SPINE)
Deposit date:2006-03-24
Release date:2006-08-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The Atx1-Ccc2 complex is a metal-mediated protein-protein interaction.
Nat.Chem.Biol., 2, 2006
2KMX
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Solution structure of the nucleotide binding domain of the human Menkes protein in the ATP-bound form
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Copper-transporting ATPase 1
Authors:Banci, L, Bertini, I, Cantini, F, Inagaki, S, Migliardi, M, Rosato, A.
Deposit date:2009-08-05
Release date:2009-12-01
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:The binding mode of ATP revealed by the solution structure of the N-domain of human ATP7A.
J.Biol.Chem., 2009

224004

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