5LOD
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![BU of 5lod by Molmil](/molmil-images/mine/5lod) | |
5CIY
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![BU of 5ciy by Molmil](/molmil-images/mine/5ciy) | Structural basis of the recognition of H3K36me3 by DNMT3B PWWP domain | Descriptor: | DNA (5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(3DR)P*GP*CP*AP*TP*GP*G)-3'), Modification methylase HhaI, ... | Authors: | Rondelet, G, DAL MASO, T, Willems, L, Wouters, J. | Deposit date: | 2015-07-13 | Release date: | 2016-03-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.594 Å) | Cite: | Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B. J.Struct.Biol., 194, 2016
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5CIU
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![BU of 5ciu by Molmil](/molmil-images/mine/5ciu) | Structural basis of the recognition of H3K36me3 by DNMT3B PWWP domain | Descriptor: | DNA (cytosine-5)-methyltransferase 3B, GLYCEROL, Histone H3.2 | Authors: | Rondelet, G, DAL MASO, T, Willems, L, Wouters, J. | Deposit date: | 2015-07-13 | Release date: | 2016-03-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B. J.Struct.Biol., 194, 2016
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6R3E
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![BU of 6r3e by Molmil](/molmil-images/mine/6r3e) | Human DNMT3B PWWP domain in complex with triisopropanolamine | Descriptor: | DNA (cytosine-5)-methyltransferase 3B,DNA (cytosine-5)-methyltransferase 3B, SULFATE ION, Triisopropanolamine | Authors: | Rondelet, G, Dal Maso, T, Wouters, J. | Deposit date: | 2019-03-20 | Release date: | 2020-04-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.269 Å) | Cite: | Targeting PWWP domain of DNMT3B for epigenetic cancer therapy: identification and structural characterization of potential protein-protein interaction inhibitors To be published
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5NV0
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![BU of 5nv0 by Molmil](/molmil-images/mine/5nv0) | Human DNMT3B PWWP domain in complex with 4-(dipropylamino)butyronitrile | Descriptor: | 4-(dipropylamino)butanenitrile, DNA (cytosine-5)-methyltransferase 3B, SULFATE ION | Authors: | Rondelet, G, Wouters, J. | Deposit date: | 2017-05-03 | Release date: | 2018-05-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.399 Å) | Cite: | Targeting PWWP domain of DNA methyltransferase 3B for epigenetic cancer therapy: Identification and structural characterization of new potential protein-protein interaction inhibitors To Be Published
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5NV7
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![BU of 5nv7 by Molmil](/molmil-images/mine/5nv7) | |
5NRS
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![BU of 5nrs by Molmil](/molmil-images/mine/5nrs) | Human DNMT3B PWWP domain in complex with N,N-bis(2-hydroxypropyl)ethanolamine | Descriptor: | (2~{S})-1-[2-hydroxyethyl-[(2~{S})-2-oxidanylpropyl]amino]propan-2-ol, DNA (cytosine-5)-methyltransferase 3B, SULFATE ION | Authors: | Rondelet, G, Wouters, J. | Deposit date: | 2017-04-25 | Release date: | 2018-05-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Targeting PWWP domain of DNA methyltransferase 3B for epigenetic cancer therapy: Identification and structural characterization of new potential protein-protein interaction inhibitors To be published
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5NR3
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![BU of 5nr3 by Molmil](/molmil-images/mine/5nr3) | Human DNMT3B PWWP domain in complex with ethambutol | Descriptor: | DNA (cytosine-5)-methyltransferase 3B, Ethambutol, SULFATE ION | Authors: | Rondelet, G, Wouters, J. | Deposit date: | 2017-04-21 | Release date: | 2018-05-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Targeting PWWP domain of DNA methyltransferase 3B for epigenetic cancer therapy: Identification and structural characterization of new potential protein-protein interaction inhibitors To be published
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5NRV
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![BU of 5nrv by Molmil](/molmil-images/mine/5nrv) | Human DNMT3B PWWP domain in complex with 6-dipropylamino-1-hexanol | Descriptor: | 6-dipropylamino-1-hexanol, DNA (cytosine-5)-methyltransferase 3B, SULFATE ION | Authors: | Rondelet, G, Wouters, J. | Deposit date: | 2017-04-25 | Release date: | 2018-06-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.075 Å) | Cite: | Targeting PWWP domain of DNA methyltransferase 3B for epigenetic cancer therapy: Identification and structural characterization of new potential protein-protein interaction inhibitors To be published
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5NRR
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![BU of 5nrr by Molmil](/molmil-images/mine/5nrr) | |
5NV2
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5NVO
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![BU of 5nvo by Molmil](/molmil-images/mine/5nvo) | Human DNMT3B PWWP domain in complex with choline | Descriptor: | CHOLINE ION, DNA (cytosine-5)-methyltransferase 3B, SULFATE ION | Authors: | Rondelet, G, Wouters, J. | Deposit date: | 2017-05-04 | Release date: | 2018-05-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Targeting PWWP domain of DNA methyltransferase 3B for epigenetic cancer therapy: Identification and structural characterization of new potential protein-protein interaction inhibitors To be published
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