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PDB: 12 件

6B5V
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BU of 6b5v by Molmil
Structure of TRPV5 in complex with econazole
分子名称: 1-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, CALCIUM ION, Transient receptor potential cation channel subfamily V member 5
著者Hughes, T.E.T, Lodowski, D.T, Huynh, K.W, Yazici, A, del Rosario, J, Kapoor, A, Basak, S, Samanta, A, Chakrapani, S, Zhou, Z.H, Filizola, M, Rohacs, T, Han, S, Moiseenkova-Bell, V.Y.
登録日2017-09-29
公開日2017-12-27
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
6PBF
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BU of 6pbf by Molmil
ZINC9155420-bound TRPV5 in nanodiscs
分子名称: (1S)-1-(4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)ethyl [(2S)-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl]acetate, Transient receptor potential cation channel subfamily V member 5
著者Hughes, T.E.T, Rosario, J.S.D, Kapoor, A, Yazici, A.T, Fluck, E.C, Filizola, M, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2019-06-13
公開日2019-11-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structure-based characterization of novel TRPV5 inhibitors.
Elife, 8, 2019
6PBE
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BU of 6pbe by Molmil
ZINC17988990-bound TRPV5 in nanodiscs
分子名称: (4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methyl 3-(3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)propanoate, Transient receptor potential cation channel subfamily V member 5
著者Hughes, T.E.T, Rosario, J.S.D, Kapoor, A, Yazici, A.T, Fluck, E.C, Filizola, M, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2019-06-13
公開日2019-11-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.78 Å)
主引用文献Structure-based characterization of novel TRPV5 inhibitors.
Elife, 8, 2019
7T6J
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BU of 7t6j by Molmil
Cryo-EM structure of TRPV5 at pH8 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6K
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BU of 7t6k by Molmil
Cryo-EM structure of TRPV5 at pH6 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6R
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BU of 7t6r by Molmil
Cryo-EM structure of TRPV5 T709D in nanodiscs in the presence of Calmodulin
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6M
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BU of 7t6m by Molmil
Cryo-EM structure of TRPV5 in nanodiscs with PI(4,5)P2 at pH6 state 1
分子名称: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6L
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BU of 7t6l by Molmil
Cryo-EM structure of TRPV5 at pH5 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6Q
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BU of 7t6q by Molmil
Cryo-EM structure of TRPV5 T709D with PI(4,5)P2 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6P
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BU of 7t6p by Molmil
Cryo-EM structure of TRPV5 T709D in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6O
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BU of 7t6o by Molmil
Cryo-EM structure of TRPV5 in nanodiscs at pH6 state 3
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6N
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BU of 7t6n by Molmil
Cryo-EM structure of TRPV5 in nanodiscs at pH6 state 2
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022

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件を2024-11-06に公開中

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